Amygdala central nucleus lesions disrupt increments, but not decrements, in conditioned stimulus processing.

Abstract:

:The effects of neurotoxic lesions of the amygdala central nucleus (CN) on changes in the associability of a conditioned stimulus (CS) in appetitive Pavlovian conditioning were examined in 2 experiments with rats. In Experiment 1, CN lesions had no effect on the reduction in the associability of a CS produced by preexposure to that cue (latent inhibition). In Experiment 2, CN lesions prevented the enhancement of the associability of a CS that is normally observed when an inconsistent predictive relation is arranged between that CS and another cue. The results support previous claims that the amygdala CN is involved in broad-based incremental, but not decremental, changes in the processing of CSs in Pavlovian conditioning.

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Holland PC,Gallagher M

doi

10.1037//0735-7044.107.2.246

subject

Has Abstract

pub_date

1993-04-01 00:00:00

pages

246-53

issue

2

eissn

0735-7044

issn

1939-0084

journal_volume

107

pub_type

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