A genetic dissociation of learning and recall in Caenorhabditis elegans.

Abstract:

:A learning event can be dissociated into 3 components: acquisition, storage, and recall. When the laboratory wild-type strain of Caenorhabditis elegans (N2 strain) is exposed to benzaldehyde in the absence of food, the worms display a reduction of their attractive response to this volatile odorant. This results from the association between benzaldehyde and a nutrient-deficient environment. Another wild-type isolate, the CB4856 strain, fails to display this decreased response to benzaldehyde after exposure to benzaldehyde in the absence of food. However, like the N2 strain, when tested to isoamyl alcohol after benzaldehyde conditioning, the CB4856 strain displays a decreased isoamyl alcohol response. Therefore, the CB4856 strain does not have an acquisition deficit, but it suffers from a recall deficit specific to benzaldehyde.

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Atkinson-Leadbeater K,Nuttley WM,van der Kooy D

doi

10.1037/0735-7044.118.6.1206

subject

Has Abstract

pub_date

2004-12-01 00:00:00

pages

1206-13

issue

6

eissn

0735-7044

issn

1939-0084

pii

2004-21410-006

journal_volume

118

pub_type

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