Motor cortex lesions do not affect learning or performance of the eyeblink response in rabbits.

Abstract:

:The possible modulatory role of motor cortex in classical conditioning of the eyeblink response was examined by ablating anterior neocortex in rabbits and training them with an auditory conditioned stimulus (CS) and an airpuff unconditioned stimulus (US) in either a delay (Experiment 1) or a trace (Experiment 2) conditioning paradigm. Topographic measures such as amplitude and onset latency were assessed during conditioning sessions for conditioned responses (CRs) and on separate test days for unconditioned responses (URs) by using a range of US intensities. No lesion effects were observed for learning or performance measures in acquisition or retention of either delay or trace conditioning. During trace conditioning, lesioned rabbits did, however, exhibit a trend toward impairment and demonstrated significantly longer CR latencies. Damage to motor and frontal cortex does not significantly affect eyeblink response performance or learning in either a delay or a trace conditioning paradigm.

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Ivkovich D,Thompson RF

doi

10.1037//0735-7044.111.4.727

subject

Has Abstract

pub_date

1997-08-01 00:00:00

pages

727-38

issue

4

eissn

0735-7044

issn

1939-0084

journal_volume

111

pub_type

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