Abstract:
:The effects of peripherally administered leucine-enkephalin on the acquisition and retention of active avoidance behavior was studied in mice. Mice received 4 training trials on Day 1, 24 test trials on Day 2, and 10 test trials on Day 5. Leucine-enkephalin impaired the aquisition of avoidance behavior when administered before testing on Day 2. Impairment of retention was demonstrated on Day 2 and Day 5 when leucine-enkephalin was administered immediately after training on Day 1, results indicating the long-term nature of the enkephalin effect. There was no effect of leucine-enkephalin when administered just prior to testing on Day 5. The impairing effect was attenuated but not blocked by naloxone. The pattern of the results from the different tests supports the hypothesis that leucine-enkephalin impairs both acquisition of learning and memory consolidation.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Dana RC,Martinez JL Jrdoi
10.1037//0735-7044.100.2.185subject
Has Abstractpub_date
1986-04-01 00:00:00pages
185-9issue
2eissn
0735-7044issn
1939-0084journal_volume
100pub_type
杂志文章abstract::Six females rats were trained to lever press under a free operant shock-postponement schedule. Each subject had a yoked control which received shock whenever the subject did. The shock-postponement interval (R-S) was varied from 5, 10, 20, 40, to 80 s over blocks of sessions. Corticosteroid levels were taken prior to ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.98.6.1094
更新日期:1984-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.108.1.44
更新日期:1994-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2009-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2005-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.121.6.1364
更新日期:2007-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.117.6.1318
更新日期:2003-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.108.5.981
更新日期:1994-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:1991-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:1990-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2014-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1037//0735-7044.97.4.541
更新日期:1983-08-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2015-08-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.105.2.272
更新日期:1991-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.113.1.103
更新日期:1999-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2008-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:1994-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2012-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.101.4.489
更新日期:1987-08-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.103.5.1028
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.101.5.626
更新日期:1987-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.109.2.305
更新日期:1995-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:1994-06-01 00:00:00