Dissociations between appetitive and consummatory responses by pharmacological manipulations of reward-relevant brain regions.

abstract：:The hippocampus is important for the acquisition of new memories. It is also one of the few regions in the adult mammalian brain that can generate new nerve cells. The authors tested the hypothesis that voluntary exercise increases neurogenesis and enhances spatial learning in mice selectively bred for high levels of ...

journal_title：Behavioral neuroscience

authors： Rhodes JS,van Praag H,Jeffrey S,Girard I,Mitchell GS,Garland T Jr,Gage FH

更新日期：2003-10-01 00:00:00

abstract：:Rhesus monkeys were trained on 2 versions of delayed nonmatching-to-sample, one with multiple pairs of objects and the other with a single pair, to evaluate their ability to remember objects. They then received either bilateral aspiration lesions of the anterior rhinal cortex or bilateral excitotoxic lesions of the am...

journal_title：Behavioral neuroscience

authors： Murray EA,Gaffan EA,Flint RW Jr

更新日期：1996-02-01 00:00:00

abstract：:The striatum is implicated in response selection and performance, the dorsal striatum in sensorimotor control and habit learning, and the ventral striatum in motivation and rewarded behaviors. Ventral striatal lesions produce performance changes on food-reinforced, progressive-ratio (PR) schedules, but the effects of ...

journal_title：Behavioral neuroscience

authors： Eagle DM,Humby T,Dunnett SB,Robbins TW

更新日期：1999-08-01 00:00:00

abstract：:The present series of three experiments was concerned with the effects of morphine and the morphine antagonist naloxone on the development of a classical aversive heart rate (HR) conditioned response (CR) to a tone conditioned stimulus (CS) paired with an electric shock unconditioned stimulus (US). In the first study,...

journal_title：Behavioral neuroscience

authors： Mahalik T,Fitzgerald RD

更新日期：1988-04-01 00:00:00

abstract：:Two different strains of mice, C57BL/6J and BALB/c, with hippocampal, cortical, or sham lesions, underwent contextual fear conditioning. In both strains, contextual fear, as measured by the freezing response, was significantly impaired in hippocampus-lesioned animals compared with sham control animals. Fear conditioni...

journal_title：Behavioral neuroscience

authors： Chen C,Kim JJ,Thompson RF,Tonegawa S

更新日期：1996-10-01 00:00:00

abstract：:Acetylcholine (ACh) and noradrenaline (NA) release in the olfactory bulb (OB) of ewes was monitored using microdialysis. Both ACh and NA release increased at parturition in multiparous but not in primiparous ewes. However, vaginocervical stimulation performed 6 hr postpartum induced an increase of ACh and NA release i...

journal_title：Behavioral neuroscience

authors： Lévy F,Guevara-Guzman R,Hinton MR,Kendrick KM,Keverne EB

更新日期：1993-08-01 00:00:00

abstract：:The authors have recently shown that attenuation of an external response feedback leads to excessive lever-pressing that is not associated with attempts to collect reward, and they have suggested that this may be an analogue to "unreasonable" excessive behavior characteristic of obsessive-compulsive disorder. The pres...

journal_title：Behavioral neuroscience

authors： Joel D,Avisar A,Doljansky J

更新日期：2001-12-01 00:00:00

abstract：:An acoustic stimulus previously paired with footshock elicits stereotyped increases in arterial pressure and heart rate and induces freezing behavior in freely behaving rats. Although the arterial pressure and freezing responses differ between groups given paired and random presentations of the tone and shock, the inc...

journal_title：Behavioral neuroscience

authors： Iwata J,LeDoux JE

更新日期：1988-02-01 00:00:00

abstract：:The sensitivity of several inbred strains of mice was assessed for ethanol's effects on activity, body temperature, ataxia, balance, and the righting reflex. Genotypic correlations among the mean responses for the strains were estimated as indexes of pleiotropic influences of genes on drug responses. Three major group...

journal_title：Behavioral neuroscience

authors： Crabbe JC

更新日期：1983-04-01 00:00:00

abstract：:Female rats drink more 3% NaCl solution than do males, both when they need sodium (need-induced sodium intake or sodium appetite) and when they do not (need-free sodium intake). The sexual dimorphism of sodium intake is a secondary sexual characteristic because after castration at 1 day of age male rats drank 3% NaCl ...

journal_title：Behavioral neuroscience

authors： Chow SY,Sakai RR,Witcher JA,Adler NT,Epstein AN

更新日期：1992-02-01 00:00:00

abstract：:Only the function relating the required pulse frequency to the interburst interval discriminates between the priming effect and the rewarding effect: Separating two short bursts of pulses has no effect on their combined rewarding effect, but it enhances their priming effect. There are significant nonscalar differences...

journal_title：Behavioral neuroscience

authors： Sax L,Gallistel CR

更新日期：1991-12-01 00:00:00

abstract：:There is evidence that the nitric oxide (NO)/soluble guanylyl cyclase (sGC)/cGMP-dependent protein kinase (PKG) signaling pathway in the basal lateral amygdala and hippocampus plays a key role in memory processing, but it is not known if this NO signaling pathway in the nucleus accumbens (Gomes et al., 2006), a known ...

journal_title：Behavioral neuroscience

authors： Shen F,Wang N,Qi C,Li YJ,Cui CL

更新日期：2014-08-01 00:00:00

abstract：:Two experiments used an associative blocking design to study the role of dopamine receptors in the nucleus accumbens shell (AcbSh) and core (AcbC) in fear prediction error. Rats in the experimental groups were trained to a visual fear-conditioned stimulus (conditional stimulus [CS]) A in Stage I, whereas rats in the c...

journal_title：Behavioral neuroscience

authors： Li SS,McNally GP

更新日期：2015-08-01 00:00:00

abstract：:In humans and some nonhuman vertebrates, a sound containing brief silent gaps can be rendered perceptually continuous by inserting noise into the gaps. This so-called "continuity illusion" arises from a phenomenon known as "auditory induction" and results in the perception of complete auditory objects despite fragment...

journal_title：Behavioral neuroscience

authors： Baugh AT,Ryan MJ,Bernal XE,Rand AS,Bee MA

更新日期：2016-02-01 00:00:00

abstract：:The authors have previously demonstrated that Purkinje cell-degeneration (pcd) mutant mice are impaired in eyeblink conditioning (L. Chen et al., 1996a). The present study addresses the following 3 questions: (a) whether pcd mice perceive the conditioned and unconditioned stimuli as well as the wild-type mice, (b) whe...

journal_title：Behavioral neuroscience

authors： Chen L,Bao S,Thompson RF

更新日期：1999-02-01 00:00:00

abstract：:In order to examine a possible interaction between thyroxine and estradiol in the control of feeding, 14 ovariectomized adult female rats were given daily injections of 9.8 micrograms/100 g of body weight of 1-thyroxine (T). Another 14 rats received 0.15 ml of saline (S) subcutaneously each day, and food intake was me...

journal_title：Behavioral neuroscience

authors： Young JK

更新日期：1986-04-01 00:00:00

abstract：:The role of the pedunculopontine tegmental nucleus (PPTg) in stimulus-reward learning was assessed by testing the effects of PPTg lesions on performance in visual autoshaping and conditioned reinforcement (CRf) paradigms. Rats with PPTg lesions were unable to learn an association between a conditioned stimulus (CS) an...

journal_title：Behavioral neuroscience

authors： Inglis WL,Olmstead MC,Robbins TW

更新日期：2000-04-01 00:00:00

abstract：:Amnesic patients (n = 8), who have severely impaired declarative memory, learned a probabilistic classification task at the same rate as normal subjects (n = 16) but subsequently were impaired on transfer tests that required flexible use of their task knowledge. A second group of controls (n = 20) rated the questions ...

journal_title：Behavioral neuroscience

authors： Reber PJ,Knowlton BJ,Squire LR

更新日期：1996-10-01 00:00:00

abstract：:It has been proposed that the cognitive dysfunction observed in patients with schizophrenia reflects a failure in cognitive control, in particular an inability to use task-relevant information to guide behavior. Using a prefrontal-dependent task designed to reflect aspects of cue and response conflict seen in human co...

journal_title：Behavioral neuroscience

authors： Haddon JE,Killcross S

更新日期：2011-06-01 00:00:00

abstract：:The role of the thalamus in memory is potentially very complex. However, most studies on the memory impairments of thalamic lesions have focused on retrospective memory, rarely on prospective memory. To explore the effect of thalamic lesions on event-based prospective memory (EBPM) and time-based prospective memory (T...

journal_title：Behavioral neuroscience

authors： Cheng H,Tian Y,Hu P,Wang J,Wang K

更新日期：2010-02-01 00:00:00

abstract：:Supplemental choline during early stages of development can result in long-lasting improvements to memory function. In addition, pre- or postnatal choline has been shown to be protective against some of the adverse effects of early alcohol exposure. The present experiment examined whether supplemental choline given to...

journal_title：Behavioral neuroscience

authors： Hunt PS

更新日期：2012-08-01 00:00:00

abstract：:Relations between sleep and memory were examined as a function of aging in rats. Sleep (24 hr), passive avoidance retention, and choline acetyltransferase (CAT) activity were assessed in 3 age-groups (6, 15, and 24 months old). Age-related alterations were evident in sleep, memory, and cortical and striatal CAT activi...

journal_title：Behavioral neuroscience

authors： Stone WS,Altman HJ,Berman RF,Caldwell DF,Kilbey MM

更新日期：1989-08-01 00:00:00

abstract：:Adult rats that were isolated from the mother and nest for 1 hr per day from Postnatal Day 2 to 9 were studied. Controls consisted of handled littermates as well as separate litters that were never handled. As adults, animals were given either a pharmacological challenge (1.0 or 2.0 mg/kg amphetamine) or an environmen...

journal_title：Behavioral neuroscience

authors： Kehoe P,Shoemaker WJ,Triano L,Callahan M,Rappolt G

更新日期：1998-02-01 00:00:00

abstract：:Donoghue and Wise (1982) identified an area AGm in the rat that they take to be a nonprimary motor area. In the present experiments, therefore, this area was removed bilaterally in rats. The animals were poor at relearning a visual conditional motor task but were able to learn spatial delayed alternation as rapidly as...

journal_title：Behavioral neuroscience

authors： Passingham RE,Myers C,Rawlins N,Lightfoot V,Fearn S

更新日期：1988-02-01 00:00:00

abstract：:Two experiments were conducted to determine the effectiveness of strychnine sulfate in attenuating the amnesia induced in mice by small doses of cycloheximide (CYC). Previously, reversal of CYC-induced amnesia catecholamine agonists has been taken as evidence that protein synthesis inhibitors induce amnesia via an inh...

journal_title：Behavioral neuroscience

authors： Leccese AP,Quinton EE

更新日期：1983-04-01 00:00:00

abstract：:Methylphenidate (MPD) is widely prescribed for attention-deficit/hyperactivity disorder in the United States. Patients, mostly school-age children, are taking the drug orally. To simulate the human condition, the authors used a cracker to administer methylphenidate orally (without the stress of handling) from Postnata...

journal_title：Behavioral neuroscience

authors： Zhu N,Weedon J,Dow-Edwards DL

更新日期：2007-12-01 00:00:00

abstract：:Infusing conscious unrestrained rats with either 0.5 M NaCl-CSF or 0.7 M sucrose-CSF into the lateral cerebral ventricle (IVT) at 38 microliters/hr for 4 hr induced drinking. Although the infusates were nearly equiosmotic, water drinking during the 0.5 M NaCl-CSF was greater than during 0.7 M sucrose-CSF. However, IVT...

journal_title：Behavioral neuroscience

authors： Osborne PG,Denton DA,Weisinger RS

更新日期：1987-06-01 00:00:00

abstract：:A discrete stimulus (flashing light) was paired with cocaine (20 mg/kg) to induce conditioned locomotion. To identify brain regions activated during this response, Fos was measured with immunohistochemistry. Although paired subjects displayed robust conditioned locomotion, Fos was not increased in any limbic brain reg...

journal_title：Behavioral neuroscience

authors： Hotsenpiller G,Horak BT,Wolf ME

更新日期：2002-08-01 00:00:00

abstract：:Similar to elderly humans, aged Long-Evans rats exhibit individual differences in performance on tasks that critically depend on the medial temporal lobe memory system. Although reduced memory performance is common, close to half of aged rats in this outbred rodent population perform within the range of young subjects...

journal_title：Behavioral neuroscience

authors： Haberman RP,Monasterio A,Branch A,Gallagher M

更新日期：2019-10-01 00:00:00

abstract：:Neuromuscular impairment by ethanol likely involves complex effects on balance, gait, muscle strength, and other features of motor coordination. The present experiments showed that relative sensitivity to ethanol-induced motor impairment in serotonin 1B (5-HT(1B)) null mutant and control mice was task dependent. We fo...

journal_title：Behavioral neuroscience

authors： Boehm SL 2nd,Schafer GL,Phillips TJ,Browman KE,Crabbe JC

更新日期：2000-04-01 00:00:00