Oral methylphenidate improves spatial learning and memory in pre- and periadolescent rats.

abstract：:Stages of formation of memory and the roles of different forebrain structures in memory formation were investigated by injecting various agents into the brains of chicks close to the time of peck-avoidance training. With L-glutamate injected bilaterally into the hyperstriatum 5 min pretraining, retention was good 1 mi...

journal_title：Behavioral neuroscience

authors： Patterson TA,Alvarado MC,Warner IT,Bennett EL,Rosenzweig MR

更新日期：1986-12-01 00:00:00

abstract：:Reactivation of an already consolidated memory makes it labile for a period of several hrs, which are required for its reconsolidation. Evidence suggests that the return of conditioned fear through spontaneous recovery, reinstatement, or renewal can be prevented by blockading this reconsolidation process using pharmac...

journal_title：Behavioral neuroscience

authors： Meir Drexler S,Merz CJ,Hamacher-Dang TC,Marquardt V,Fritsch N,Otto T,Wolf OT

更新日期：2014-08-01 00:00:00

abstract：:Previous research shows that prenatal binge ethanol exposure during gestation days (GD) 17 to 20 of the rat, increases postnatal ethanol intake and enhances ethanol's palatability, both effects being mediated by the opioid system. The amniotic fluid of the last period of gestation (GD 20) of the rat has been found to ...

journal_title：Behavioral neuroscience

authors： Díaz-Cenzano E,Chotro MG

更新日期：2010-06-01 00:00:00

abstract：:The role of the hippocampus in associative learning was investigated in 3 experiments with rats as subjects. Hippocampal rats were impaired in the acquisition of conditioned responding both when food was signaled by the insertion of a lever (Experiment 1) and when the presentation of auditory or visual events served a...

journal_title：Behavioral neuroscience

authors： Good M,Honey RC

更新日期：1991-08-01 00:00:00

abstract：:The effects of peripherally administered leucine-enkephalin on the acquisition and retention of active avoidance behavior was studied in mice. Mice received 4 training trials on Day 1, 24 test trials on Day 2, and 10 test trials on Day 5. Leucine-enkephalin impaired the aquisition of avoidance behavior when administer...

journal_title：Behavioral neuroscience

authors： Dana RC,Martinez JL Jr

更新日期：1986-04-01 00:00:00

abstract：:Cutaneous desensitization of the upper, rostral snout by bilateral section of the infraorbital nerves in lactating Norway rat dams markedly, but transiently, disrupted retrieval and licking of pups, nursing behavior, and fighting with a strange male intruder. Removal of the mystacial vibrissae, which provide major inp...

journal_title：Behavioral neuroscience

authors： Stern JM,Kolunie JM

更新日期：1991-12-01 00:00:00

abstract：:The female steroid hormone 17beta-estradiol enhances synaptic transmission and the magnitude of longterm potentiation (LTP) in adult rodent hippocampal slices. Long-term depression (LTD), another form of synaptic plasticity, occurs more prominently in hippocampal slices from aged rodents. A decrease in LTP has been re...

journal_title：Behavioral neuroscience

authors： Foy MR,Baudry M,Foy JG,Thompson RF

更新日期：2008-04-01 00:00:00

abstract：:Behavioral changes induced by inescapable shock were examined in six strains of mice. Exposure to shock provoked time-dependent disturbances of shuttle escape performance. In some strains the shock treatment did not affect escape performance, whereas in others profound performance deficits were evident. The inescapabl...

journal_title：Behavioral neuroscience

authors： Shanks N,Anisman H

更新日期：1988-12-01 00:00:00

abstract：:In different experiments, pairings of a drug (pentobarbital or morphine) or place as the conditioned stimulus (CS) with lithium-induced sickness as the unconditioned stimulus (US) were given to rats to produce Pavlovian conditioning. Control rats received unpaired exposures. In the test, each rat was exposed to the CS...

journal_title：Behavioral neuroscience

authors： Lett BT

更新日期：1992-02-01 00:00:00

abstract：:Acute mid-thoracic spinal cord transection eliminates hindlimb air-stepping in neonatal rats suspended in harnesses and administered L-DOPA. Because spinal cord transection eliminates all descending inputs to the hindlimb locomotor circuits, this experiment determined if coadministration of L-DOPA and quipazine (serot...

journal_title：Behavioral neuroscience

authors： McEwen ML,Van Hartesveldt C,Stehouwer DJ

更新日期：1997-08-01 00:00:00

abstract：:Dopaminergic blocking agents have been known to suppress intracranial self-stimulation, but whether the suppression results from a reduction in the rewarding value of stimulation or from motor deficits has remained controversial. We have resolved this controversy by developing an operant technique minimally dependent ...

journal_title：Behavioral neuroscience

authors： Fantie BD,Nakajima S

更新日期：1987-10-01 00:00:00

abstract：:A unilateral microinjection of morphine into the amygdala impaired fear conditioning to both a conditioned stimulus (CS) paired with shock and the context where shock occurred, whereas a microinjection of morphine into the nucleus accumbens (NA) spared fear conditioning to the CS but impaired, in a dose-dependent and ...

journal_title：Behavioral neuroscience

authors： Westbrook RF,Good AJ,Kiernan MJ

更新日期：1997-10-01 00:00:00

abstract：:Odor mixture perception can be configural (the mixture is qualitatively different from the components) or elemental (the components are recognizable). Some have argued that configural properties are dependent on chemical similarity and possible overlap at the receptor level. The authors show that a binary mixture in w...

journal_title：Behavioral neuroscience

authors： Kay LM,Lowry CA,Jacobs HA

更新日期：2003-10-01 00:00:00

abstract：:The present experiment was designed to determine whether infusions of naloxone into specific brain sites can block sexual reinforcement as evaluated with the conditioned place preference procedure. Methylnaloxonium (5 micrograms/cannula) was infused bilaterally either into the medial preoptic area (MPOA) or into the n...

journal_title：Behavioral neuroscience

authors： Agmo A,Gómez M

更新日期：1993-10-01 00:00:00

abstract：:Rats with 192 IgG-saporin lesions of the nucleus basalis magnocellularis (NBM) and sham-operated rats were trained in either a simple discrimination paradigm assessing simple association learning or a negative patterning paradigm assessing configural association learning. In the simple discrimination task, rats were r...

journal_title：Behavioral neuroscience

authors： Butt AE,Noble MM,Rogers JL,Rea TE

更新日期：2002-04-01 00:00:00

abstract：:This study assessed the activity of head direction (HD) cells during performance of a spatial reference memory task on a radial arm maze. Rats were trained to select a maze arm located in a constant position in relation to a salient extramaze visual landmark. HD cell discharge properties remained relatively stable acr...

journal_title：Behavioral neuroscience

authors： Dudchenko PA,Taube JS

更新日期：1997-02-01 00:00:00

abstract：:Fluoxetine is the only selective serotonin reuptake inhibitor registered for the treatment of major depressive disorder in pediatric populations, despite reports that it is disproportionately associated with an array of adverse side effects that include agitation, hostility, and overt acts of pathological aggression a...

journal_title：Behavioral neuroscience

authors： Ricci LA,Melloni RH Jr

更新日期：2012-10-01 00:00:00

abstract：:In Experiment 1, Long-Evans rat pups received fimbria-fornix transections or sham surgery on Postnatal Day 10 (PND10) and were then trained on PND23 to perform either a discrete-trials delayed alternation (DA) or a simple position discrimination (PD) task in a T maze. Rat pups in both surgical conditions learned the P...

journal_title：Behavioral neuroscience

authors： Freeman JH Jr,Stanton ME

更新日期：1991-06-01 00:00:00

abstract：:We used the tail-flick response of rats to study the role of opioid receptors in illness-induced hyperalgesia. An intraperitoneal injection of lithium chloride (LiCl) produced hyperalgesia that was blocked in a dose-dependent manner by subcutaneous injection of the opioid antagonist naloxone. Neither hyperalgesia nor ...

journal_title：Behavioral neuroscience

authors： McNally GP,Johnston IN,Westbrook RF

更新日期：2000-12-01 00:00:00

abstract：:Two experiments measured the response-enhancing effects of oral stimulation in young rats with no feeding experience. In Experiment 1, pups were implanted with oral cannulas and deprived for 0, 6, or 24 hr. In nondeprived rats, sucrose exposure transiently sensitized oral responding to subsequent stimuli for several m...

journal_title：Behavioral neuroscience

authors： Myers KP,Arnold HM,Hall WG

更新日期：1997-04-01 00:00:00

abstract：:In humans, congenital deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT) results in a disorder known as the Lesch-Nyhan syndrome. Patients with this disorder exhibit a prominent neurobehavioral phenotype that results in part from dysfunction of catecholaminergic systems in the striatum. HPR...

journal_title：Behavioral neuroscience

authors： Jinnah HA,Gage FH,Friedmann T

更新日期：1991-12-01 00:00:00

abstract：:These experiments examined the sufficiency of pairing an odor with either intrabulbar activation of noradrenergic beta-receptors or pharmacological stimulation of the locus coeruleus to support learned odor preferences in Postnatal Day 6-7 rat pups. The results showed that pups exposed to odor paired with beta-recepto...

journal_title：Behavioral neuroscience

authors： Sullivan RM,Stackenwalt G,Nasr F,Lemon C,Wilson DA

更新日期：2000-10-01 00:00:00

abstract：:This study investigated the role of the endogenous opioid system in maternal and affiliative behavior of group-living rhesus macaque (Macaca mulatta) mothers with a history of abusive parenting. Eighteen mothers received an injection of the opioid antagonist naltrexone or saline for 5 days per week for the first 4 wee...

journal_title：Behavioral neuroscience

authors： Graves FC,Wallen K,Maestripieri D

更新日期：2002-06-01 00:00:00

abstract：:Female ovariectomized (OVX) and sham-OVX rats were trained in a task designed to assess sustained attention. After achieving asymptotic performance, OVX rats did not exhibit the impairment in performance over blocks of trials (i.e., the vigilance decrement) observed in sham-OVX rats. Furthermore, OVX rats' performance...

journal_title：Behavioral neuroscience

authors： McGaughy J,Sarter M

更新日期：1999-12-01 00:00:00

abstract：:The acquisition and performance of a self-paced test of spatial divided attention linked with frontal cortex function were assessed in postpubertal (> 60 days) normal or gonadectomized male and female rats. Males were more accurate at detecting relatively brief visual stimuli than females, but this difference was elim...

journal_title：Behavioral neuroscience

authors： Jentsch JD,Taylor JR

更新日期：2003-02-01 00:00:00

abstract：:Prenatal testosterone exposure may be protective against disordered eating. However, prior studies have produced mixed results. Developmental differences in prenatal testosterone's protective effects on disordered eating may explain these discrepancies. Indeed, studies have differed in the age of participants assessed...

journal_title：Behavioral neuroscience

authors： Culbert KM,Breedlove SM,Sisk CL,Keel PK,Neale MC,Boker SM,Burt SA,Klump KL

更新日期：2015-02-01 00:00:00

abstract：:An influential view in the field of spatial cognition is that an obligatory geometric module constrains spatial learning and memory. In this issue, P. M. Jones, J. M. Pearce, V. J. Davies, M. A. Good, and A. McGregor (2007) showed that learning based on the geometry, or shape, of the environment requires the hippocamp...

journal_title：Behavioral neuroscience

authors： Dudchenko PA

更新日期：2007-12-01 00:00:00

abstract：:Previous studies in Long-Evans rats demonstrated a significant relationship between variation in pup licking/grooming and arched-back nursing (LG-ABN) and offspring development. However, maternal care is dynamic and exhibits significant temporal variation. In the current study, we assessed temporal variation in LG and...

journal_title：Behavioral neuroscience

authors： Jensen Peña C,Champagne FA

更新日期：2013-02-01 00:00:00

abstract：:Rats were injected with naloxone hydrochloride (3 mg/kg) or saline and subjected to preshock or no preshock prior to receiving a test shock that elicited defensive burying. Preshock was administered in a context different from, or the same as, that in which the test shock was delivered. The combination of naloxone and...

journal_title：Behavioral neuroscience

authors： Whiteside DA,Devenport LD

更新日期：1985-06-01 00:00:00

abstract：:Appetitive behaviors of rats were monitored in a runway situation following central infusions of neuroactive substances into brain areas implicated in electrical self-stimulation. Microinjections of the dopamine antagonist cis-flupentixol or the cholinergic antagonist atropine into the nucleus accumbens (Acb) severely...

journal_title：Behavioral neuroscience

authors： Ikemoto S,Panksepp J

更新日期：1996-04-01 00:00:00