Learning and retrieval of concurrently presented spatial discrimination tasks: role of the fornix.

Abstract:

:In macaque monkeys (Macaco mulatta), memory for scenes presented on touch screens is fornix dependent. However, scene learning is not a purely spatial task, and existing direct evidence for a fornix role in spatial memory comes exclusively from tasks involving learning about food-reward locations. Here the authors demonstrate that fornix transection impairs learning about spatial stimuli presented on touch screens. Using a new concurrent spatial discrimination learning task, they found that fornix transection did not impair recall of preoperatively learned problems. Relearning, on the other hand, was mildly impaired, and new learning was strongly impaired. New learning of smaller sets of harder problems was also markedly impaired, as was spatial configured learning. This pattern supports a functional specialization according to stimulus domain in the medial temporal lobe.

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Buckley MJ,Charles DP,Browning PG,Gaffan D

doi

10.1037/0735-7044.118.1.138

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

138-49

issue

1

eissn

0735-7044

issn

1939-0084

pii

2004-10963-013

journal_volume

118

pub_type

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