DREADDS: Use and application in behavioral neuroscience.

abstract：:Neonatal handling induces long-lasting effects on behaviors and stress responses. The objective of the present study was to analyze the effects of neonatal handling (from the 1st to the 10th day after delivery) on the number of cells and volume of locus coeruleus (LC) nucleus in male and female rats at 4 different age...

journal_title：Behavioral neuroscience

authors： Lucion AB,Pereira FM,Winkelman EC,Sanvitto GL,Anselmo-Franci JA

更新日期：2003-10-01 00:00:00

abstract：:A discrete stimulus (flashing light) was paired with cocaine (20 mg/kg) to induce conditioned locomotion. To identify brain regions activated during this response, Fos was measured with immunohistochemistry. Although paired subjects displayed robust conditioned locomotion, Fos was not increased in any limbic brain reg...

journal_title：Behavioral neuroscience

authors： Hotsenpiller G,Horak BT,Wolf ME

更新日期：2002-08-01 00:00:00

abstract：:Appetitive behaviors of rats were monitored in a runway situation following central infusions of neuroactive substances into brain areas implicated in electrical self-stimulation. Microinjections of the dopamine antagonist cis-flupentixol or the cholinergic antagonist atropine into the nucleus accumbens (Acb) severely...

journal_title：Behavioral neuroscience

authors： Ikemoto S,Panksepp J

更新日期：1996-04-01 00:00:00

abstract：:The possible modulatory role of motor cortex in classical conditioning of the eyeblink response was examined by ablating anterior neocortex in rabbits and training them with an auditory conditioned stimulus (CS) and an airpuff unconditioned stimulus (US) in either a delay (Experiment 1) or a trace (Experiment 2) condi...

journal_title：Behavioral neuroscience

authors： Ivkovich D,Thompson RF

更新日期：1997-08-01 00:00:00

abstract：:This study examines the effects of positive and negative feedback on performance during choice reaction time tasks to assess whether they differentially affect phasic arousal and tonic activation. Participants (N = 96) received either no feedback or signals of reward, punishment, or both during a semantic and a visuos...

journal_title：Behavioral neuroscience

authors： De Brabander B,Declerck CH,Boone C

更新日期：2002-06-01 00:00:00

abstract：:This study examined the effects of intense emotional learning on the sleep-wake state-specific electroencephalographic (EEG) activities of the basolateral (BLA) and central (CeA) nuclei of the amygdala. Rats were trained on a passive-avoidance learning (PAL) protocol that was followed by 6 hr of undisturbed polygraphi...

journal_title：Behavioral neuroscience

authors： Mavanji V,Siwek DF,Patterson EH,Spoley EE,Datta S

更新日期：2003-08-01 00:00:00

abstract：:Female rats exhibit a conditioned place preference (CPP) for a context paired with mating. The present experiment tested the hypothesis that the activation of the pelvic nerve mediates the reinforcing effects of mating for female rats. Rats underwent bilateral pelvic nerve or sham transection and then received paced m...

journal_title：Behavioral neuroscience

authors： Meerts SH,Clark AS

更新日期：2009-06-01 00:00:00

abstract：:The effects of neurotoxic lesions of the amygdala central nucleus (CN) on changes in the associability of a conditioned stimulus (CS) in appetitive Pavlovian conditioning were examined in 2 experiments with rats. In Experiment 1, CN lesions had no effect on the reduction in the associability of a CS produced by preexp...

journal_title：Behavioral neuroscience

authors： Holland PC,Gallagher M

更新日期：1993-04-01 00:00:00

abstract：:The catechol-O-methyltransferase (COMT) val158met polymorphism has received attention in schizophrenia due to its role in prefrontal dopamine catabolism. Given the rich dopaminergic innervations of the olfactory bulb and the influence of dopamine on the transmission of olfactory signals, the authors examined the influ...

journal_title：Behavioral neuroscience

authors： Kamath V,Moberg PJ,Gur RE,Doty RL,Turetsky BI

更新日期：2012-02-01 00:00:00

abstract：:This experiment was conducted to determine whether the amount of preoperative training influences the effects, on retention, of amygdala lesions induced 30 days after escape training. Rats received 1 or 10 footshock-motivated escape training trials; 30 days later, sham or neurotoxic amygdala lesions were induced. Resu...

journal_title：Behavioral neuroscience

authors： Parent MB,West M,McGaugh JL

更新日期：1994-12-01 00:00:00

abstract：:Supplemental choline during early stages of development can result in long-lasting improvements to memory function. In addition, pre- or postnatal choline has been shown to be protective against some of the adverse effects of early alcohol exposure. The present experiment examined whether supplemental choline given to...

journal_title：Behavioral neuroscience

authors： Hunt PS

更新日期：2012-08-01 00:00:00

abstract：:Previous results from our laboratory have demonstrated that 3-day-old rats given dopamine (DA)-depleting brain lesions are spared the severe behavioral dysfunctions seen after comparable brain damage in adults. This behavioral sparing is accompanied by a sprouting of serotonin (5-HT)-containing neurons in the striatum...

journal_title：Behavioral neuroscience

authors： Bruno JP,Jackson D,Zigmond MJ,Stricker EM

更新日期：1987-12-01 00:00:00

abstract：:The rat's willingness to ingest glucose after an initial intraoral intake test was probed by beginning a 2nd intraoral intake test at variable durations (1-120 min). In Experiment 1, after an initial meal of 12.5% glucose solution averaging 26.9 +/- 1.7 ml (SEM, n = 10), the size of the 2nd (probe) meal of the same st...

journal_title：Behavioral neuroscience

authors： Kaplan JM,Seeley RJ,Grill HJ

更新日期：1994-04-01 00:00:00

abstract：:The effects of various doses (40 microg/kg/hr, 300 microg/kg/hr, 600 microg/kg/hr or placebo) of hydrocortisone on tasks assessing working and declarative memory function were measured in 4 groups of 10 young men. During the infusion, participants were given an item-recognition working memory task, a paired-associate ...

journal_title：Behavioral neuroscience

authors： Lupien SJ,Gillin CJ,Hauger RL

更新日期：1999-06-01 00:00:00

abstract：:Large neocortical injuries can interfere with the initial performance of many previously learned behaviors. This dysfunction, however, may not be attributable to the loss of the memories of learned behaviors but to a failure to access memories that are spared. The results of this experiment support this hypothesis by ...

journal_title：Behavioral neuroscience

authors： LeVere TE,Brugler T,Sandin M,Gray-Silva S

更新日期：1989-06-01 00:00:00

abstract：:A previous study reported that power in the delta band of the amygdala is selectively elevated when primates are exposed to affectively ladened stimuli (Kling, Steklis, & Deutsch, 1979). Radiotelemetric recordings suggested that this elevation was greatest when the animal was confronted with conspecific behaviors that...

journal_title：Behavioral neuroscience

authors： Lloyd RL,Kling AS

更新日期：1991-04-01 00:00:00

abstract：:Previous research emphasized the impact of traumatic brain injury on cholinergic systems and associated cognitive functions. Here we addressed the converse question: Because of the available evidence indicating cognitive and neuronal vulnerabilities in humans expressing low-capacity cholinergic systems or with declini...

journal_title：Behavioral neuroscience

authors： Koshy Cherian A,Tronson NC,Parikh V,Kucinski A,Blakely RD,Sarter M

更新日期：2019-08-01 00:00:00

abstract：:Quipazine is a 5-HT2A-receptor agonist that has been used to induce motor activity and promote recovery of function after spinal cord injury in neonatal and adult rodents. Sensory stimulation also activates sensory and motor circuits and promotes recovery after spinal cord injury. In rats, tail pinching is an effectiv...

journal_title：Behavioral neuroscience

authors： Swann HE,Kauer SD,Allmond JT,Brumley MR

更新日期：2017-02-01 00:00:00

abstract：:The influence of 4-hydroxyamphetamine (4-OHAM) on food and water intake and in vivo brown adipose thermogenesis was examined in two experiments. In Experiment 1, female rats were treated with 0.00, 0.25, 0.50, 1.00, or 2.00 mg/kg 4-OHAM (ip) prior to assessment of interscapular brown adipose tissue (IBAT) thermogenesi...

journal_title：Behavioral neuroscience

authors： Wellman PJ,Watkins-Freeman PA

更新日期：1984-12-01 00:00:00

abstract：:The acoustic startle reflex (ASR) in rats is attenuated by a light paired with food or, in humans, by "pleasant" pictures. Rats were trained to barpress for lateral hypothalamus (LH) stimulation. ASR amplitudes were then measured at 4 intensities, with or without a light. Control rats that did not receive brain-stimul...

journal_title：Behavioral neuroscience

authors： Steidl S,Li L,Yeomans JS

更新日期：2001-06-01 00:00:00

abstract：:The sensitivity of several inbred strains of mice was assessed for ethanol's effects on activity, body temperature, ataxia, balance, and the righting reflex. Genotypic correlations among the mean responses for the strains were estimated as indexes of pleiotropic influences of genes on drug responses. Three major group...

journal_title：Behavioral neuroscience

authors： Crabbe JC

更新日期：1983-04-01 00:00:00

abstract：:Electrolytic microlesions aimed at the dorsomedial portion of the ventromedial nucleus (VMN) of the hypothalamus were generated, and effects on copulation, 50-kHz vocalizations, scent marking, and sexual motivation were measured. Male rats were tested before and after lesions, after castration, and after testosterone ...

journal_title：Behavioral neuroscience

authors： Harding SM,McGinnis MY

更新日期：2005-10-01 00:00:00

abstract：:Cutaneous desensitization of the upper, rostral snout by bilateral section of the infraorbital nerves in lactating Norway rat dams markedly, but transiently, disrupted retrieval and licking of pups, nursing behavior, and fighting with a strange male intruder. Removal of the mystacial vibrissae, which provide major inp...

journal_title：Behavioral neuroscience

authors： Stern JM,Kolunie JM

更新日期：1991-12-01 00:00:00

abstract：:Function of the central nucleus of the amygdala (CeA) is critical to 2 aspects of attention in associative learning: the conditioning of orienting responses (ORs) to cues paired with food, and the enhancement of cue salience by the surprising omission of expected events. Such salience enhancements have been found to d...

journal_title：Behavioral neuroscience

authors： Esber GR,Torres-Tristani K,Holland PC

更新日期：2015-04-01 00:00:00

abstract：:The neurexins are a family of presynaptic cell adhesion molecules. Human genetic studies have found heterozygous deletions affecting NRXN1 and NRXN2, encoding α-neurexin I (Nrxn1α) and α-neurexin II (Nrxn2α), in individuals with autism spectrum disorders and schizophrenia. However, the link between α-neurexin deficien...

journal_title：Behavioral neuroscience

authors： Dachtler J,Ivorra JL,Rowland TE,Lever C,Rodgers RJ,Clapcote SJ

更新日期：2015-12-01 00:00:00

abstract：:Fluoxetine is the only selective serotonin reuptake inhibitor registered for the treatment of major depressive disorder in pediatric populations, despite reports that it is disproportionately associated with an array of adverse side effects that include agitation, hostility, and overt acts of pathological aggression a...

journal_title：Behavioral neuroscience

authors： Ricci LA,Melloni RH Jr

更新日期：2012-10-01 00:00:00

abstract：:Extant research findings allow several conclusions regarding the relationship between estrogen and cognitive functioning across the female life span. First, performance on tests of verbal memory fluctuates in concert with physiological changes in ovarian hormone production during the menstrual cycle and during pregnan...

journal_title：Behavioral neuroscience

authors： Sherwin BB

更新日期：2012-02-01 00:00:00

abstract：:The cAMP-responsive element binding protein (CREB) is a transcription factor that regulates synaptic plasticity and memory formation. Studies that have used conditioned fear models have established that CREB is important for the acquisition and consolidation of fear learning. The authors demonstrate that overexpressio...

journal_title：Behavioral neuroscience

authors： Jasnow AM,Shi C,Israel JE,Davis M,Huhman KL

更新日期：2005-08-01 00:00:00

abstract：:With the use of controls not included in previous studies, evidence is presented for the existence of water-induced central excitatory state (w-CES) from analyses of pure-breeding high- and low-CES lines in the blow fly, Phormia regina. The CES lines differed in base-level responsiveness to distilled water (and to sal...

journal_title：Behavioral neuroscience

authors： Tully T,Hirsch J

更新日期：1983-02-01 00:00:00

abstract：:The hippocampus has been implicated in anxiety, novelty detection, spatial- contextual processing, and hyperactivity. Accordingly, the authors contrasted the role of the dorsal hippocampus (DH) and the basolateral amygdala complex (BLA) in an open field task that presents the onset and termination of a bright light gr...

journal_title：Behavioral neuroscience

authors： Godsil BP,Stefanacci L,Fanselow MS

更新日期：2005-10-01 00:00:00