Temporal coding of sensation: mimicking taste quality with electrical stimulation of the brain.

Abstract:

:Two experiments suggested that the temporal pattern of a taste response in the brain can convey meaningful information. In Experiment 1, rats avoided lick-contingent electrical stimulation of the nucleus of the solitary tract (NTS; the first synaptic relay for taste) when the temporal pattern of pulses mimicked the electrophysiological response to quinine, but not when the temporal pattern was randomized. In Experiment 2, rats avoided lick-contingent electrical stimulation of the NTS that mimicked the temporal pattern of a sucrose response following stimulation-illness pairings. This aversion generalized to sucrose but not to the other tastants; extinction of the aversion to electrical stimulation also extinguished the aversion to sucrose. Results replicate and extend previous findings (P. M. Di Lorenzo & G. S. Hecht, 1993).

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Di Lorenzo PM,Hallock RM,Kennedy DP

doi

10.1037/0735-7044.117.6.1423

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

1423-33

issue

6

eissn

0735-7044

issn

1939-0084

pii

2003-10460-028

journal_volume

117

pub_type

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