Mapping the substrate for brain stimulation reward by means of current-number trade-off functions.

abstract：:The authors measured food reinforcement, polymorphisms of the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes, and laboratory energy intake in 29 obese and 45 nonobese humans 18-40 years old. Food reinforcement was greater in obese than in nonobese individuals, especially in obese individuals with th...

journal_title：Behavioral neuroscience

authors： Epstein LH,Temple JL,Neaderhiser BJ,Salis RJ,Erbe RW,Leddy JJ

更新日期：2007-10-01 00:00:00

abstract：:This study examined the hypothesis that defensive responsiveness induced by threatening stimuli of biological origin is mediated by the action of endogenous corticotropin-releasing factor (CRF). Rats were exposed for 15 min to a large open field containing a small chamber. Twenty-four hours later, rats received intrac...

journal_title：Behavioral neuroscience

authors： Takahashi LK,Kalin NH,Baker EW

更新日期：1990-04-01 00:00:00

abstract：:This series of experiments investigated the role of a prefrontal cortical-dorsal striatal circuit in attention, using a continuous performance task of sustained and spatially divided visual attention. A unilateral excitotoxic lesion of the medial prefrontal cortex and a contralateral lesion of the medial caudate-putam...

journal_title：Behavioral neuroscience

authors： Christakou A,Robbins TW,Everitt BJ

更新日期：2001-08-01 00:00:00

abstract：:The present series of three experiments was concerned with the effects of morphine and the morphine antagonist naloxone on the development of a classical aversive heart rate (HR) conditioned response (CR) to a tone conditioned stimulus (CS) paired with an electric shock unconditioned stimulus (US). In the first study,...

journal_title：Behavioral neuroscience

authors： Mahalik T,Fitzgerald RD

更新日期：1988-04-01 00:00:00

abstract：:Amiloride-sensitive sodium channels in taste buds appear to play a key role in the response to NaCl stimulation, at least in adult rats. The researchers examined whether neonatal rats, which display an exaggerated preference for hypertonic NaCl solutions, lack functional amiloride-sensitive sodium channels. NaCl intak...

journal_title：Behavioral neuroscience

authors： Sollars SI,Bernstein IL

更新日期：1994-10-01 00:00:00

abstract：:Transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) from olfactory sensory neurons to the olfactory bulb as well as odor detection and discrimination were examined in rats in which each nasal epithelium had been irrigated with 0.1-0.5 ml 5% zinc sulfate. After treatment, rats showed few or no deficits ...

journal_title：Behavioral neuroscience

authors： Slotnick B,Glover P,Bodyak N

更新日期：2000-08-01 00:00:00

abstract：:The addition of a dual runway configuration did not disrupt the successful performance of normal animals, nor did it improve the deficit of septal rats on the Maier three-table spatial integration task. Both groups of animals displayed a preference for the outside runway configuration during exploration. During testin...

journal_title：Behavioral neuroscience

authors： Herrmann T,Poucet B,Ellen P

更新日期：1985-08-01 00:00:00

abstract：:Single unit activity was recorded from the rat hippocampal CA1 and CA3 subfields, dentate gyrus (DG), entorhinal cortex (EC), subicular complex (SB), motor cortex (MC), prefrontal cortex (PFC), and dorsomedial thalamus (DMT) during performance of a continuous non-matching-to-sample task. The rats made go and no-go res...

journal_title：Behavioral neuroscience

authors： Sakurai Y

更新日期：1990-04-01 00:00:00

abstract：:These studies were designed to determine the dose-response autonomic and behavioral thermoregulatory effects and the motor effects of dopamine (DA) and prostaglandin E1 (PGE1) injected into the lateral cerebral ventricles of rats. These studies were made possible with a computer-controlled thermocline that permits fre...

journal_title：Behavioral neuroscience

authors： Marques PR,Spencer RL,Burks TF,McDougal JN

更新日期：1984-10-01 00:00:00

abstract：:Adult male rats consumed 50-150% more 0.5 M NaCl solution than females did during a 7-hr drinking test when robust salt appetite was elicited by dietary sodium deprivation for 8 days, daily injections of deoxycorticosterone, or adrenalectomy followed by 2 days of sodium deprivation. In contrast, male rats drank much l...

journal_title：Behavioral neuroscience

authors： Scheidler MG,Verbalis JG,Stricker EM

更新日期：1994-02-01 00:00:00

abstract：:Four experiments were conducted in rats within 2 hr of cesarean delivery to assess antinociception at birth and its possible opioid bases. Morphine antinociception was established in a dose-dependent fashion (0.0625-5.0 mg/kg bw). Analgesia was naloxone (1.0 mg/kg) reversible. In succeeding experiments, antinociceptio...

journal_title：Behavioral neuroscience

authors： Blass EM,Jackson AM,Smotherman WP

更新日期：1991-10-01 00:00:00

abstract：:Preadolescent mice have been shown to be differentially susceptible to the effects of both acute and chronic nicotine exposure on contextual fear learning relative to adults. For this study, we tested the effects of chronic nicotine exposure in preadolescence on adulthood extinction and spontaneous recovery of fear me...

journal_title：Behavioral neuroscience

authors： Zeid D,Gould TJ

更新日期：2018-08-01 00:00:00

abstract：:Although decorticated rats are able to engage in play, their play is abnormal in three ways. First, decorticates do not display the normal, age-related shifts in defensive strategies during development. Second, decorticates do not modify their defensive tactics in response to the social identity of their partners. Thi...

journal_title：Behavioral neuroscience

authors： Bell HC,McCaffrey DR,Forgie ML,Kolb B,Pellis SM

更新日期：2009-12-01 00:00:00

abstract：:Guinea pig pups that were separated from their mothers and placed into a novel environment for 90 min showed an increase in dopamine (DA) turnover (ratio of metabolites to DA) in the septum compared with undisturbed baseline controls. Pups placed into the novel environment with their mothers exhibited an intermediate ...

journal_title：Behavioral neuroscience

authors： Tamborski A,Lucot JB,Hennessy MB

更新日期：1990-08-01 00:00:00

abstract：:The ontogeny of associative learning in delay (750-ms conditional stimulus [CS], 650-ms interstimulus interval [ISI]), long-delay (1,350-ms CS, 1,250-ms ISI), and trace (750-ms CS, 500-ms trace interval, 1,250-ms ISI) eyeblink conditioning was examined in 5-month-old human infants and adults. Infants and adults showed...

journal_title：Behavioral neuroscience

authors： Herbert JS,Eckerman CO,Stanton ME

更新日期：2003-12-01 00:00:00

abstract：:Anterograde amnesia (AA), forgetting of events that occur following a traumatic episode, has recently been demonstrated by using a mild decrease in temperature (hypothermia) as the amnestic agent. However, no data currently exist to indicate if an increase in body temperature (hyperthermia) might affect memory process...

journal_title：Behavioral neuroscience

authors： Ahlers ST,Riccio DC

更新日期：1987-06-01 00:00:00

abstract：:Mother rabbits nurse once daily with circadian periodicity. The authors investigated brain structures involved in regulating this activity by quantifying c-FOS-immunoreactive (IR) cells in the forebrain of: (1) mothers killed on postpartum Day 1 (PPD 1) after nursing (Group 1) or not given pups (Group 2); (2) mothers ...

journal_title：Behavioral neuroscience

authors： González-Mariscal G,Jiménez A,Chirino R,Beyer C

更新日期：2009-08-01 00:00:00

abstract：:Mice with genetically associated variations in the number and density of granule cells in the dentate gyrus were tested for open-field activity, spatial maze learning, and two-way avoidance conditioning. The number of granule cells was not associated with any behavior measured. Only avoidance conditioning was related ...

journal_title：Behavioral neuroscience

authors： Wimer C,Wimer RE,Wimer JS

更新日期：1983-12-01 00:00:00

abstract：:The spontaneously hypertensive rat (SHR) has been suggested as a possible animal model of attention-deficit/hyperactivity disorder (ADHD). Reductions in the volume of the cerebellum and impairments in cerebellar-dependent eyeblink conditioning have been observed in ADHD, prompting investigation into whether SHRs also ...

journal_title：Behavioral neuroscience

authors： Chess AC,Green JT

更新日期：2008-02-01 00:00:00

abstract：:Prenatal testosterone exposure may be protective against disordered eating. However, prior studies have produced mixed results. Developmental differences in prenatal testosterone's protective effects on disordered eating may explain these discrepancies. Indeed, studies have differed in the age of participants assessed...

journal_title：Behavioral neuroscience

authors： Culbert KM,Breedlove SM,Sisk CL,Keel PK,Neale MC,Boker SM,Burt SA,Klump KL

更新日期：2015-02-01 00:00:00

abstract：:The defensive withdrawal reflex of the mantle organs (gill, siphon, and mantle shelf) of the marine mollusc Aplysia californica has been the subject of numerous studies investigating the cellular and molecular mechanisms of learning. In behavioral experiments, the reflex has been monitored by means of two different re...

journal_title：Behavioral neuroscience

authors： Stopfer M,Carew TJ

更新日期：1987-04-01 00:00:00

abstract：:The role of the pedunculopontine tegmental nucleus (PPTg) in stimulus-reward learning was assessed by testing the effects of PPTg lesions on performance in visual autoshaping and conditioned reinforcement (CRf) paradigms. Rats with PPTg lesions were unable to learn an association between a conditioned stimulus (CS) an...

journal_title：Behavioral neuroscience

authors： Inglis WL,Olmstead MC,Robbins TW

更新日期：2000-04-01 00:00:00

abstract：:Supplemental choline during early stages of development can result in long-lasting improvements to memory function. In addition, pre- or postnatal choline has been shown to be protective against some of the adverse effects of early alcohol exposure. The present experiment examined whether supplemental choline given to...

journal_title：Behavioral neuroscience

authors： Hunt PS

更新日期：2012-08-01 00:00:00

abstract：:In the separated arms conditioned cue preference (CCP) task rats are trained by confining them in one arm of an eight-arm radial maze with food and in another arm on the opposite side of the maze with no food on alternate days. After two such trials, rats prefer the food-paired arm when allowed to move freely between ...

journal_title：Behavioral neuroscience

authors： Naeem M,White NM

更新日期：2011-02-01 00:00:00

abstract：:PDAPP transgenic mice have been shown to develop age dependently much of the cerebral histopathology associated with Alzheimer's disease. PDAPP mice (3-10 months old) were tested in a battery of memory tasks to determine whether they develop memory-behavioral deficits and whether these deficits occur before or after a...

journal_title：Behavioral neuroscience

authors： Dodart JC,Meziane H,Mathis C,Bales KR,Paul SM,Ungerer A

更新日期：1999-10-01 00:00:00

abstract：:Function of the central nucleus of the amygdala (CeA) is critical to 2 aspects of attention in associative learning: the conditioning of orienting responses (ORs) to cues paired with food, and the enhancement of cue salience by the surprising omission of expected events. Such salience enhancements have been found to d...

journal_title：Behavioral neuroscience

authors： Esber GR,Torres-Tristani K,Holland PC

更新日期：2015-04-01 00:00:00

abstract：:Large neocortical injuries can interfere with the initial performance of many previously learned behaviors. This dysfunction, however, may not be attributable to the loss of the memories of learned behaviors but to a failure to access memories that are spared. The results of this experiment support this hypothesis by ...

journal_title：Behavioral neuroscience

authors： LeVere TE,Brugler T,Sandin M,Gray-Silva S

更新日期：1989-06-01 00:00:00

abstract：:The present experiment monitored bilateral eyelid responses during eyeblink conditioning in rats trained with a unilateral unconditioned stimulus (US). Three groups of rats were used to determine if cross-modal savings occurs when the location of the US is switched from one eye to the other. Rats in each group first r...

journal_title：Behavioral neuroscience

authors： Campolattaro MM,Buss EW,Freeman JH

更新日期：2015-12-01 00:00:00

abstract：:Microstructural analysis of licking behavior in the rat was conducted (a) to describe in detail the characteristics of benzodiazepine-induced changes in ingestion and (b) to determine if the changes are consistent with an alteration in palatability. The effects of the benzodiazepine receptor (BZR) agonist midazolam (0...

journal_title：Behavioral neuroscience

authors： Higgs S,Cooper SJ

更新日期：1998-04-01 00:00:00

abstract：:Dopamine in the medial preoptic area (MPOA) facilitates copulation in male rats, and nitric oxide (NO) regulates basal and female-stimulated MPOA dopamine release. Microinjection of L-nitro-arginine methyl ester (L-NAME, an NO synthesis inhibitor) into the MPOA blocked copulation in naive rats and impaired copulation ...

journal_title：Behavioral neuroscience

authors： Lagoda G,Muschamp JW,Vigdorchik A,Hull EM

更新日期：2004-12-01 00:00:00