Abstract:
:In order to measure tinnitus induced by sodium salicylate injections, 84 pigmented rats, distributed among 14 groups in five experiments, were used in a conditioned suppression paradigm. In Experiment 1, all groups were trained with a conditioned stimulus (CS) consisting of the offset of a continuous background noise. One group began salicylate injections before Pavlovian training, a second group started injections after training, and a control group received daily saline injections. Resistance to extinction was profound when injections started before training, but minimal when initiated after training, which suggests that salicylate-induced effects acquired differential conditioned value. In Experiment 2 we mimicked the salicylate treatments by substituting a 7 kHz tone in place of respective injections, resulting in effects equivalent to salicylate-induced behavior. In a third experiment we included a 3 kHz CS, and again replicated the salicylate findings. In Experiment 4 we decreased the motivational level, and the sequential relation between salicylate-induced effects and suppression training was retained. Finally, no salicylate effects emerged when the visual modality was used. These findings support the demonstration of phantom auditory sensations in animals.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Jastreboff PJ,Brennan JF,Coleman JK,Sasaki CTdoi
10.1037//0735-7044.102.6.811subject
Has Abstractpub_date
1988-12-01 00:00:00pages
811-22issue
6eissn
0735-7044issn
1939-0084journal_volume
102pub_type
杂志文章abstract::Past work has demonstrated robust brain changes in cholecystokinin (CCK-8) following social defeat. Here the authors analyzed brain regional, CCK-8, substance P, corticotropin releasing factor (CRF), and neuropeptide Y levels in adult male Long-Evans rats defeated in a resident-intruder social aggression paradigm, as ...
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pub_type: 杂志文章
doi:10.1037/0735-7044.121.6.1364
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.99.1.22
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pub_type: 杂志文章
doi:10.1037//0735-7044.106.1.172
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.116.5.912
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.115.3.614
更新日期:2001-06-01 00:00:00
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pub_type: 杂志文章
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.97.2.323
更新日期:1983-04-01 00:00:00
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更新日期:2015-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:1995-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000142
更新日期:2016-06-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.111.5.873
更新日期:1997-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1037/a0015334
更新日期:2009-06-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.101.3.333
更新日期:1987-06-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.118.4.730
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pub_type: 杂志文章
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2001-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2009-10-01 00:00:00
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更新日期:2008-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.105.2.223
更新日期:1991-04-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.99.4.765
更新日期:1985-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2009-08-01 00:00:00