Medial prefrontal lesions impair performance in an operant delayed nonmatch to sample working memory task.

abstract：:Stages of formation of memory and the roles of different forebrain structures in memory formation were investigated by injecting various agents into the brains of chicks close to the time of peck-avoidance training. With L-glutamate injected bilaterally into the hyperstriatum 5 min pretraining, retention was good 1 mi...

journal_title：Behavioral neuroscience

authors： Patterson TA,Alvarado MC,Warner IT,Bennett EL,Rosenzweig MR

更新日期：1986-12-01 00:00:00

abstract：:An acoustic stimulus previously paired with footshock elicits stereotyped increases in arterial pressure and heart rate and induces freezing behavior in freely behaving rats. Although the arterial pressure and freezing responses differ between groups given paired and random presentations of the tone and shock, the inc...

journal_title：Behavioral neuroscience

authors： Iwata J,LeDoux JE

更新日期：1988-02-01 00:00:00

abstract：:Neuropsin (kallikrein-related peptidase 8) is concentrated in the hippocampus, amygdala, olfactory bulb, and prefrontal cortex. Earlier studies showed that protease deficiency causes a significant impairment of early-phase long-term potentiation in the Schaffer collateral pathway and hippocampus-dependent memory in th...

journal_title：Behavioral neuroscience

authors： Horii Y,Yamasaki N,Miyakawa T,Shiosaka S

更新日期：2008-06-01 00:00:00

abstract：:The effects of neurotoxic lesions of the amygdala central nucleus (CN) on changes in the associability of a conditioned stimulus (CS) in appetitive Pavlovian conditioning were examined in 2 experiments with rats. In Experiment 1, CN lesions had no effect on the reduction in the associability of a CS produced by preexp...

journal_title：Behavioral neuroscience

authors： Holland PC,Gallagher M

更新日期：1993-04-01 00:00:00

abstract：:Multi-unit recording of siphon nerve activity in intact Aplysia california with chronically implanted cuff electrodes provided a monitor of activity in a central pattern generator, the Interneuron II (Int II) network, which produces large siphon and gill contractions both spontaneously and after tactile stimulation of...

journal_title：Behavioral neuroscience

authors： Eberly LB,Pinsker HM

更新日期：1984-08-01 00:00:00

abstract：:Female rats exhibit a conditioned place preference (CPP) for a context paired with mating. The present experiment tested the hypothesis that the activation of the pelvic nerve mediates the reinforcing effects of mating for female rats. Rats underwent bilateral pelvic nerve or sham transection and then received paced m...

journal_title：Behavioral neuroscience

authors： Meerts SH,Clark AS

更新日期：2009-06-01 00:00:00

abstract：:Previous results from our laboratory have demonstrated that 3-day-old rats given dopamine (DA)-depleting brain lesions are spared the severe behavioral dysfunctions seen after comparable brain damage in adults. This behavioral sparing is accompanied by a sprouting of serotonin (5-HT)-containing neurons in the striatum...

journal_title：Behavioral neuroscience

authors： Bruno JP,Jackson D,Zigmond MJ,Stricker EM

更新日期：1987-12-01 00:00:00

abstract：:A differentiation was made between dispositional memory and representational memory. A delayed-nonmatching-to-sample task in a T-maze operationalized this distinction. Experimental brain lesions in posterior septum and in prelimbic cortex resulted in amnesia for representational memories. The amnesia ameliorated as a ...

journal_title：Behavioral neuroscience

authors： Thomas GJ,Spafford PS

更新日期：1984-06-01 00:00:00

abstract：:The rat's willingness to ingest glucose after an initial intraoral intake test was probed by beginning a 2nd intraoral intake test at variable durations (1-120 min). In Experiment 1, after an initial meal of 12.5% glucose solution averaging 26.9 +/- 1.7 ml (SEM, n = 10), the size of the 2nd (probe) meal of the same st...

journal_title：Behavioral neuroscience

authors： Kaplan JM,Seeley RJ,Grill HJ

更新日期：1994-04-01 00:00:00

abstract：:Classical conditioning of the rabbit eyeblink response was used to study the effects of cerebellar lesions on performance in animals trained with low-intensity unconditioned stimuli (US). Animals were trained with 1 of 2 low-intensity corneal-airpuff USs paired with a tone-conditioned stimulus. This study confirms ear...

journal_title：Behavioral neuroscience

authors： Ivkovich D,Lockard JM,Thompson RF

更新日期：1993-06-01 00:00:00

abstract：:Ovariectomized female rats treated with estradiol benzoate (EB) and progesterone (P) were infused intracerebroventricularly with a low (200 ng) or high (1 microgram) dose of oxytocin (OT). The low dose of OT facilitated lordosis behavior only during the dark phase of the light-dark cycle in females that were pretreate...

journal_title：Behavioral neuroscience

authors： Schumacher M,Coirini H,Pfaff DW,McEwen BS

更新日期：1991-06-01 00:00:00

abstract：:Adult rats that were isolated from the mother and nest for 1 hr per day from Postnatal Day 2 to 9 were studied. Controls consisted of handled littermates as well as separate litters that were never handled. As adults, animals were given either a pharmacological challenge (1.0 or 2.0 mg/kg amphetamine) or an environmen...

journal_title：Behavioral neuroscience

authors： Kehoe P,Shoemaker WJ,Triano L,Callahan M,Rappolt G

更新日期：1998-02-01 00:00:00

abstract：:Feeding-related gustatory, olfactory, and visual activation of the orbitofrontal cortex (OFC) decreases following satiety. Previous neurophysiological studies have concentrated on the caudolateral OFC (clOFC). We describe satiety-induced modulation of 23 gustatory, 5 water, and 15 control neurons in the medial OFC (mO...

journal_title：Behavioral neuroscience

authors： Pritchard TC,Nedderman EN,Edwards EM,Petticoffer AC,Schwartz GJ,Scott TR

更新日期：2008-02-01 00:00:00

abstract：:This study examined the hypothesis that defensive responsiveness induced by threatening stimuli of biological origin is mediated by the action of endogenous corticotropin-releasing factor (CRF). Rats were exposed for 15 min to a large open field containing a small chamber. Twenty-four hours later, rats received intrac...

journal_title：Behavioral neuroscience

authors： Takahashi LK,Kalin NH,Baker EW

更新日期：1990-04-01 00:00:00

abstract：:Using Hermissenda as subjects, massed-trials training deficits were examined. Associative pairings of light and rotation induced a progressively greater conditioned foot contraction in response to light as the intertrial interval (ITI) was extended (up to 8 min). In contrast, a short ITI (30 s) produced no evidence of...

journal_title：Behavioral neuroscience

authors： Muzzio IA,Ramirez RR,Talk AC,Matzel LD

更新日期：1999-02-01 00:00:00

abstract：:The role of the hippocampus in associative learning was investigated in 3 experiments with rats as subjects. Hippocampal rats were impaired in the acquisition of conditioned responding both when food was signaled by the insertion of a lever (Experiment 1) and when the presentation of auditory or visual events served a...

journal_title：Behavioral neuroscience

authors： Good M,Honey RC

更新日期：1991-08-01 00:00:00

abstract：:Amnesic patients (n = 8), who have severely impaired declarative memory, learned a probabilistic classification task at the same rate as normal subjects (n = 16) but subsequently were impaired on transfer tests that required flexible use of their task knowledge. A second group of controls (n = 20) rated the questions ...

journal_title：Behavioral neuroscience

authors： Reber PJ,Knowlton BJ,Squire LR

更新日期：1996-10-01 00:00:00

abstract：:Environmental cues associated with drug administration elicit neural activation in circuits involved in cognitive processes and emotional regulation. An important question is whether the neural activation observed is specific to the drug-paired environment or is due to a generalized activation induced by previous drug...

journal_title：Behavioral neuroscience

authors： Schroeder BE,Kelley AE

更新日期：2002-08-01 00:00:00

abstract：:Ejaculation-induced reward in the male rat was evaluated by the conditioned place-preference paradigm. It was supposed that ejaculation induces a reward state such that it can be conditioned to environmental stimuli. Males were allowed to ejaculate once and were then immediately transferred to a place-preference cage....

journal_title：Behavioral neuroscience

authors： Agmo A,Berenfeld R

更新日期：1990-02-01 00:00:00

abstract：:Two experiments suggested that the temporal pattern of a taste response in the brain can convey meaningful information. In Experiment 1, rats avoided lick-contingent electrical stimulation of the nucleus of the solitary tract (NTS; the first synaptic relay for taste) when the temporal pattern of pulses mimicked the el...

journal_title：Behavioral neuroscience

authors： Di Lorenzo PM,Hallock RM,Kennedy DP

更新日期：2003-12-01 00:00:00

abstract：:For 5 days, rats were exposed to shocks that were signalled by a light 0, 33, 66, or 100% of the time. Basal hormone levels and responses to a light-shock pair were measured daily. Greater predictability was associated with higher basal plasma corticosterone and norepinephrine levels indicative of chronic stress. Habi...

journal_title：Behavioral neuroscience

authors： Pitman DL,Natelson BH,Ottenweller JE,McCarty R,Pritzel T,Tapp WN

更新日期：1995-08-01 00:00:00

abstract：:Rats with perirhinal cortex lesions were sequentially trained in a rectangular water tank on a series of 3 visual discriminations, each between mirror-imaged stimuli. When these same discriminations were tested concurrently, the rats were forced to use a configural strategy to solve the problems effectively. There was...

journal_title：Behavioral neuroscience

authors： Aggleton JP,Albasser MM,Aggleton DJ,Poirier GL,Pearce JM

更新日期：2010-02-01 00:00:00

abstract：:The catechol-O-methyltransferase (COMT) val158met polymorphism has received attention in schizophrenia due to its role in prefrontal dopamine catabolism. Given the rich dopaminergic innervations of the olfactory bulb and the influence of dopamine on the transmission of olfactory signals, the authors examined the influ...

journal_title：Behavioral neuroscience

authors： Kamath V,Moberg PJ,Gur RE,Doty RL,Turetsky BI

更新日期：2012-02-01 00:00:00

abstract：:Auditory streaming describes a percept in which a sequential series of sounds either is segregated into different streams or is integrated into one stream based on differences in their spectral or temporal characteristics. This phenomenon has been analyzed in human subjects (psychophysics) and European starlings (neur...

journal_title：Behavioral neuroscience

authors： Dolležal LV,Itatani N,Günther S,Klump GM

更新日期：2012-12-01 00:00:00

abstract：:In young rats, the pattern of neuronal ensemble activity correlations expressed among hippocampal pyramidal cells during behavior persists during subsequent quiet wakefulness and slow-wave sleep, a process that may facilitate the consolidation of episodic memories. The present study explored the hypothesis that age-re...

journal_title：Behavioral neuroscience

authors： Gerrard JL,Kudrimoti H,McNaughton BL,Barnes CA

更新日期：2001-12-01 00:00:00

abstract：:Four rhesus monkeys (Macaca mulatta) were trained to learn novel sets of visuomotor associations in 50 trials or less, within single test sessions. After bilateral ablation of the orbital and ventral prefrontal cortex, the monkeys lost the ability to learn these associations within a session, although they could learn...

journal_title：Behavioral neuroscience

authors： Bussey TJ,Wise SP,Murray EA

更新日期：2001-10-01 00:00:00

abstract：:Previous research emphasized the impact of traumatic brain injury on cholinergic systems and associated cognitive functions. Here we addressed the converse question: Because of the available evidence indicating cognitive and neuronal vulnerabilities in humans expressing low-capacity cholinergic systems or with declini...

journal_title：Behavioral neuroscience

authors： Koshy Cherian A,Tronson NC,Parikh V,Kucinski A,Blakely RD,Sarter M

更新日期：2019-08-01 00:00:00

abstract：:Two experiments examined whether the pudendal and pelvic autonomic nerves are important for pacing behavior shown by the female rat during mating. Ovariectomized female rats received bilateral transection of the pudendal (Pux), pelvic (Pex), or pudendal and pelvic (Pu + Pex) nerves or were sham-operated (Shx). Lordoti...

journal_title：Behavioral neuroscience

authors： Erskine MS

更新日期：1992-08-01 00:00:00

abstract：:Two preparations in which sensory nerve stimulation was used to obtain peripherally induced spinal fixation in spinal rats are described. In the first preparation, proportionally greater amounts of persisting poststimulation flexor muscle contraction, as measured by a force displacement transducer, were produced as st...

journal_title：Behavioral neuroscience

authors： Steinmetz JE,Patterson MM

更新日期：1985-02-01 00:00:00

abstract：:Alert wakefulness (W) and rapid eye movement sleep (REM) are remarkably similar on several measures of brain activity, but 2 differences in REM are reduced sensory responsiveness and atonia in postural muscles. Pontine tegmental lesions create REM without atonia (REM-A), releasing motor behavior. In 9 cats, we studied...

journal_title：Behavioral neuroscience

authors： Morrison AR,Sanford LD,Ball WA,Mann GL,Ross RJ

更新日期：1995-10-01 00:00:00