Effects of exposure to stressors of varying predictability on adrenal function in rats.

Abstract:

:For 5 days, rats were exposed to shocks that were signalled by a light 0, 33, 66, or 100% of the time. Basal hormone levels and responses to a light-shock pair were measured daily. Greater predictability was associated with higher basal plasma corticosterone and norepinephrine levels indicative of chronic stress. Habituation of the corticosterone response was also less in the groups with greater predictability. However, predictability did not affect plasma prolactin or epinephrine responses. Because the endocrine systems responded differently, it is unlikely that the changes were due to a unitary process. Greater predictability appeared to be more stressful in this paradigm. Both associative and nonassociative factors have major roles in determining the hormonal responses to repeated presentation of stressors.

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Pitman DL,Natelson BH,Ottenweller JE,McCarty R,Pritzel T,Tapp WN

doi

10.1037//0735-7044.109.4.767

subject

Has Abstract

pub_date

1995-08-01 00:00:00

pages

767-76

issue

4

eissn

0735-7044

issn

1939-0084

journal_volume

109

pub_type

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