Abstract:
:Fifty-eight 4-day-old male rats were studied. Peripheral desensitization was induced in 36 rats by sc administration of capsaicin in increasing doses (350, 700, 1,400, 2,100, and 2,800 micrograms) on 5 consecutive days. When adult, 9 treated and 5 control rats were chronically implanted with a lateral intracerebroventricular (icv) guide cannula. This tube was used for icv capsaicin injection. Eleven treated rats and 6 controls were implanted with a hypothalamic thermode. Hypothalamic heating was activated with the aid of this water-perfused thermode. Twenty-eight rats, 12 control and 16 treated, were injected ip and sc with capsaicin. Results showed that in control rats, icv, ip, and sc capsaicin injections produced a fall in body (core) temperature and an increase in cutaneous temperature. These changes are attributed to cutaneous vasodilation. In capsaicin-treated rats, sc and ip injections had no effect on body temperature. However, neonatal treatment did not inhibit the effect of capsaicin on body temperature. Furthermore, in these rats thermoregulatory behavior for fresh air was identical to that of controls at all ambient temperatures before and during hypothalamic heating. These results suggest that the central heat receptors responsible for autonomic and behavioral thermoregulation in the treated rats function normally when icv capsaicin is injected or when the hypothalamus is heated. In contrast, neonatal injection of capsaicin produced an inhibition of the heat loss mechanisms induced by ip or sc capsaicin, i.e., by stimulation of the peripheral nervous system.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Dib Bdoi
10.1037//0735-7044.97.5.822subject
Has Abstractpub_date
1983-10-01 00:00:00pages
822-5issue
5eissn
0735-7044issn
1939-0084journal_volume
97pub_type
杂志文章abstract::Animals with sham operations, hippocampal formation, or small and large parietal cortex lesions were trained in a task that required memory for short or long lists of items (spatial locations). More specifically, on any one trial, a rat is presented with 2, 4, 6, 8, or 10 items (spatial locations) on a 12-arm radial m...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.103.1.84
更新日期:1989-02-01 00:00:00
abstract::Amnesic patients (n = 8), who have severely impaired declarative memory, learned a probabilistic classification task at the same rate as normal subjects (n = 16) but subsequently were impaired on transfer tests that required flexible use of their task knowledge. A second group of controls (n = 20) rated the questions ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.110.5.861
更新日期:1996-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.102.1.101
更新日期:1988-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.118.5.1080
更新日期:2004-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0018306
更新日期:2010-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000247
更新日期:2018-08-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.100.2.185
更新日期:1986-04-01 00:00:00
abstract::Previous research emphasized the impact of traumatic brain injury on cholinergic systems and associated cognitive functions. Here we addressed the converse question: Because of the available evidence indicating cognitive and neuronal vulnerabilities in humans expressing low-capacity cholinergic systems or with declini...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000310
更新日期:2019-08-01 00:00:00
abstract::The effects of lesions of the medial dorsal thalamic nucleus (MD) on blocking and latent inhibition (LI) of the rat eyeblink response were examined in the present study. Previous work has demonstrated that the cingulate cortex and related thalamic areas are involved in processing conditioning stimuli throughout traini...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.116.2.276
更新日期:2002-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.105.3.487
更新日期:1991-06-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.118.6.1206
更新日期:2004-12-01 00:00:00
abstract::Acetylcholine (ACh) and noradrenaline (NA) release in the olfactory bulb (OB) of ewes was monitored using microdialysis. Both ACh and NA release increased at parturition in multiparous but not in primiparous ewes. However, vaginocervical stimulation performed 6 hr postpartum induced an increase of ACh and NA release i...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.107.4.662
更新日期:1993-08-01 00:00:00
abstract::Heart rate measures were used to examine the functional response of young chimpanzees and orangutans to acoustic stimuli, including white noise and chimpanzee vocalizations (threat, stress, and alarm). The initial response of the animals to all stimuli was characterized by a prominent cardiac deceleration and an incre...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.103.2.235
更新日期:1989-04-01 00:00:00
abstract::Endogenous opioids mediate some reward processes involving both natural (food, sweet taste) and artificial (morphine, heroin) rewards. In contrast, sexual behavior (which is also reinforcing) is generally inhibited by opioids. To establish the role of endogenous opioids for a newly described natural reinforcer, namely...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.122.2.416
更新日期:2008-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.102.3.404
更新日期:1988-06-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000191
更新日期:2017-04-01 00:00:00
abstract::Previous findings are discordant regarding the effects of perinatal lesions of Cortical Areas 17 and 18 on visual discrimination learning in cats. Three potential determinants of such sparing were investigated: age at lesion (4 or 181 days), age at testing (3 or 9 months), and stimulus complexity. Age at testing was n...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.103.6.1176
更新日期:1989-12-01 00:00:00
abstract::The C. elegans mutants, lrn-1 and lrn-2, are impaired in associative learning using conditioned taste cues. Both mutants are defective in associative learning about appetitive and aversive events, indicating that lrn-1 and lrn-2 exert effects across motivational boundaries. In a new olfactory associative learning para...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.113.2.358
更新日期:1999-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.107.1.147
更新日期:1993-02-01 00:00:00
abstract::This study assessed the activity of head direction (HD) cells during performance of a spatial reference memory task on a radial arm maze. Rats were trained to select a maze arm located in a constant position in relation to a salient extramaze visual landmark. HD cell discharge properties remained relatively stable acr...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.111.1.3
更新日期:1997-02-01 00:00:00
abstract::The role of the hippocampus in associative learning was investigated in 3 experiments with rats as subjects. Hippocampal rats were impaired in the acquisition of conditioned responding both when food was signaled by the insertion of a lever (Experiment 1) and when the presentation of auditory or visual events served a...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.105.4.499
更新日期:1991-08-01 00:00:00
abstract::The advent of the selective cholinergic toxin, 192 IgG-saporin, dramatically shaped subsequent research on the role of the basal forebrain in learning and memory. In particular, several articles (including the authors' 1995 Behavioral Neuroscience paper; M. G. Baxter, D. J. Bucci, L. K., Gorman, R. G. Wiley, & M. Gall...
journal_title:Behavioral neuroscience
pub_type: 评论,杂志文章
doi:10.1037/a0033781
更新日期:2013-10-01 00:00:00
abstract::Previous results from our laboratory have demonstrated that 3-day-old rats given dopamine (DA)-depleting brain lesions are spared the severe behavioral dysfunctions seen after comparable brain damage in adults. This behavioral sparing is accompanied by a sprouting of serotonin (5-HT)-containing neurons in the striatum...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.101.6.806
更新日期:1987-12-01 00:00:00
abstract::These studies were designed to determine the dose-response autonomic and behavioral thermoregulatory effects and the motor effects of dopamine (DA) and prostaglandin E1 (PGE1) injected into the lateral cerebral ventricles of rats. These studies were made possible with a computer-controlled thermocline that permits fre...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.98.5.858
更新日期:1984-10-01 00:00:00
abstract::Aggressive tendencies may be linked to the psychopharmacology of cocaine, yet few experimental approaches have been brought to bear on understanding the neurobiological implications of cocaine exposure during the developmentally sensitive period of adolescence. In this issue, Melloni and coauthors (L. A. Ricci, J. M. ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章,评审
doi:10.1037/0735-7044.118.5.1143
更新日期:2004-10-01 00:00:00
abstract::Adult male rats were implanted with chronically indwelling recording electrodes in the dentate hilus of one hemisphere and bipolar stimulating electrodes in the contralateral entorhinal cortex (EC). Daily measurements were then made of the amplitude of responses, evoked through the crossed temporodentate (CTD) pathway...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.101.2.179
更新日期:1987-04-01 00:00:00
abstract::In sighted humans, light intensity, timing, exposure duration, and spectral composition of light are important to entrain the endogenous circadian pacemaker to the 24-h day-night cycle. We tested the impact of two realistic office lighting conditions during the afternoon on subjective sleepiness, hormonal secretion, a...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0026702
更新日期:2012-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.99.3.436
更新日期:1985-06-01 00:00:00
abstract::Sustained potential shifts (SPS) were recorded for 10 s from the surface of the optic tectum of toads presented with live prey and moving artificial prey stimuli. On the anterior tectal surface, a negative SPS was followed by a positive wave; the converse was true for the posterior tectum. Some animals were immobilize...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.109.1.150
更新日期:1995-02-01 00:00:00
abstract::Rat fetuses were exposed to cocaine, lidocaine, or saline on Gestational Day 20 or 21 to provide information about cocaine effects on behavior during prenatal development. Cocaine was administered into the cisterna magna of individual fetal subjects to restrict effects to the CNS. Behavioral effects of cocaine were co...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.108.6.1179
更新日期:1994-12-01 00:00:00