Mediodorsal thalamic lesions and Pavlovian conditioning of heart rate and eyeblink responses in the rabbit.

Abstract:

:Rabbits received ibotenic acid lesions of the mediodorsal nucleus of the thalamus (MD) or sham lesions. These animals were compared on 4 sessions of Pavlovian eyeblink and heart rate conditioning, in which a tone was the conditioned stimulus and a paraorbital electrical shock was the unconditioned stimulus. Lesions of MD retarded acquisition of the eyeblink conditioned response and abolished the late-occurring tachycardiac component of the heart rate conditioned response. The data are compatible with previous experiments suggesting that MD participates in the sympathetic control associated with somatomotor learning.

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Buchanan SL,Thompson RH

doi

10.1037//0735-7044.104.6.912

subject

Has Abstract

pub_date

1990-12-01 00:00:00

pages

912-8

issue

6

eissn

0735-7044

issn

1939-0084

journal_volume

104

pub_type

杂志文章
  • One-trial odor-reward association: a form of event memory not dependent on hippocampal function.

    abstract::To examine whether the hippocampus is required for memory for unique experiences independent of their spatial or temporal context, the authors devised a novel task that requires rats to remember odor-reward associations formed within a single training trial. Unlike previous tests of 1-trial memory, in this task new as...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.118.3.526

    authors: Wood ER,Agster KM,Eichenbaum H

    更新日期:2004-06-01 00:00:00

  • Aged rats with intact memory show distinctive recruitment in cortical regions relative to young adults in a cue mismatch task.

    abstract::Similar to elderly humans, aged Long-Evans rats exhibit individual differences in performance on tasks that critically depend on the medial temporal lobe memory system. Although reduced memory performance is common, close to half of aged rats in this outbred rodent population perform within the range of young subjects...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/bne0000332

    authors: Haberman RP,Monasterio A,Branch A,Gallagher M

    更新日期:2019-10-01 00:00:00

  • Medial temporal lesions in monkeys impair memory on a variety of tasks sensitive to human amnesia.

    abstract::Monkeys with conjoint bilateral lesions of the hippocampus and amygdala were impaired on four different tests of memory (delayed retention of object discriminations, concurrent discrimination, delayed response, and delayed nonmatching to sample). Because tests involving delays and distractions are known to be especial...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.99.1.22

    authors: Zola-Morgan S,Squire LR

    更新日期:1985-02-01 00:00:00

  • Fovea and foveation in Parkinson's disease.

    abstract::Nondemented Parkinson's disease (PD) patients report problems on nonmotor tasks that depend on visual or visuospatial abilities. In PD, foveal vision is impaired. Experimental studies in humans and monkeys established that foveal processing and visuospatial attention may be linked through saccadic eye movements. Sacca...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章,评审

    doi:10.1037/a0031225

    authors: Bodis-Wollner I,Glazman S,Yerram S

    更新日期:2013-04-01 00:00:00

  • Sustained potential shifts in the toad tectum reflect prey-catching and avoidance behavior.

    abstract::Sustained potential shifts (SPS) were recorded for 10 s from the surface of the optic tectum of toads presented with live prey and moving artificial prey stimuli. On the anterior tectal surface, a negative SPS was followed by a positive wave; the converse was true for the posterior tectum. Some animals were immobilize...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.1.150

    authors: Laming PR,Ocherashvili IV,Nicol AU,Roughan JV,Laming BA

    更新日期:1995-02-01 00:00:00

  • Developmental exposure to methimazole increases anxiety behavior in zebrafish.

    abstract::The role of thyroid hormones in vertebrate development has been well documented for several decades. As hypothyroidism during critical periods of development can cause defects to the development of every major organ system, including brain, eye, and general morphology, we hypothesized that hypothyroidism would affect ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/bne0000087

    authors: Reider M,Connaughton VP

    更新日期:2015-10-01 00:00:00

  • Preferential use of the landmark navigational system by head direction cells in rats.

    abstract::Previous studies have identified a population of cells recorded in the postsubiculum and the anterior thalamic nucleus (ATN) that discharge as a function of an animal's head direction (HD) in the horizontal plane. The present experiments monitored HD cell activity when rats were confronted with a situation in which di...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.1.49

    authors: Goodridge JP,Taube JS

    更新日期:1995-02-01 00:00:00

  • Spatial judgment in Parkinson's disease: Contributions of attentional and executive dysfunction.

    abstract::Spatial judgment is impaired in Parkinson's disease (PD), with previous research suggesting that disruptions in attention and executive function are likely contributors. If judgment of center places demands on frontal systems, performance on tests of attention/executive function may correlate with extent of bias in PD...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/bne0000329

    authors: Salazar RD,Moon KLM,Neargarder S,Cronin-Golomb A

    更新日期:2019-08-01 00:00:00

  • The role of the medial prefrontal cortex in the play fighting of rats.

    abstract::Although decorticated rats are able to engage in play, their play is abnormal in three ways. First, decorticates do not display the normal, age-related shifts in defensive strategies during development. Second, decorticates do not modify their defensive tactics in response to the social identity of their partners. Thi...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0017617

    authors: Bell HC,McCaffrey DR,Forgie ML,Kolb B,Pellis SM

    更新日期:2009-12-01 00:00:00

  • Analysis of learning deficits in aged rats on the W-track continuous spatial alternation task.

    abstract::Young and aged animals were tested on a spatial alternation task that consisted of two interleaved components: (1) an "outbound" or alternation component (working memory) and (2) an "inbound" component, requiring the animal to remember to return to a central location in space (spatial memory). In the present study, ag...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/bne0000269

    authors: Kapellusch AJ,Lester AW,Schwartz BA,Smith AC,Barnes CA

    更新日期:2018-12-01 00:00:00

  • Exploration, anxiety, and spatial memory in transgenic anophthalmic mice.

    abstract::Contradictory results are found in the literature concerning the role of vision in the perception of space or in spatial navigation, in part because of the lack of murine models of total blindness used so far. The authors evaluated the spatial abilities of anophthalmic transgenic mice. These mice did not differ qualit...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Buhot MC,Dubayle D,Malleret G,Javerzat S,Segu L

    更新日期:2001-04-01 00:00:00

  • What does a pigeon (Columba livia) brain look like during homing? selective examination of ZENK expression.

    abstract::Lesion studies have shown that the avian hippocampus plays a crucial role in homing pigeon (Columba livia) navigation. Using the expression of the immediate early gene protein ZENK in intact pigeons, the authors found regional variation in hippocampal activation as a consequence of homing and, necessarily, the behavio...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.118.4.845

    authors: Shimizu T,Bowers AN,Budzynski CA,Kahn MC,Bingman VP

    更新日期:2004-08-01 00:00:00

  • The relation of feeding and activity following septal lesions in rats.

    abstract::The patterns of intake of liquid diet and water were recorded in diet-deprived rats with septal lesions and neurologically intact controls during the first hour of diet access. The occurrences of grooming, resting/sleeping, and exploring were also recorded. Both groups of rats consumed similar amounts of diet in one m...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.100.3.416

    authors: Flynn FW,Evey LA,Steele TL,Mitchell JC

    更新日期:1986-06-01 00:00:00

  • Rapid effects of 17β-estradiol on male copulatory behaviors are not elicited by the novel membrane active estrogenic compound STX.

    abstract::Estrogens have been shown to rapidly promote male copulatory behaviors with a time-course that suggests rapid signaling events are involved. The present study tested the hypothesis that estrogen acts through a novel Gq protein-coupled membrane estrogen receptor (ER). Thus, either estradiol (E2), STX (a diphenylacrylam...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0032950

    authors: Kaufman KR,Kelly MJ,Roselli CE

    更新日期:2013-08-01 00:00:00

  • Double dissociation of fornix and caudate nucleus lesions on acquisition of two water maze tasks: further evidence for multiple memory systems.

    abstract::The present study examined the effect of lesions of the caudate nucleus or fimbria-fornix on the acquisition of two water maze tasks. In both tasks, two rubber balls with different visual patterns were used as platforms (i.e., cues). The "correct" cue was attached to a submerged rectangular platform and could be mount...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.106.3.439

    authors: Packard MG,McGaugh JL

    更新日期:1992-06-01 00:00:00

  • Increases in vocalization and motor reflex thresholds are influenced by the site of morphine microinjection: comparisons following administration into the periaqueductal gray, ventral medulla, and spinal subarachnoid space.

    abstract::The relative influence of morphine microinjected into the periaqueductal gray, ventral medulla (nucleus raphé magnus or nucleus reticularis gigantocellularis), or spinal subarachnoid space on the thresholds of responses organized at spinal (spinal motor reflexes, SMRs), medullary (vocalizations elicited during shock, ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.3.502

    authors: Borszcz GS

    更新日期:1995-06-01 00:00:00

  • Strychnine increases acoustic startle amplitude but does not alter short-term or long-term habituation.

    abstract::Theories of habituation have included an increase in postsynaptic inhibition as one possible mechanism underlying response decrement following repetitive stimulus presentation. In this study, the glycine antagonist strychnine (1.0 mg/kg, ip, 10 min pretreatment) was used to investigate the involvement of glycinergic n...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.98.6.955

    authors: Kehne JH,Davis M

    更新日期:1984-12-01 00:00:00

  • Modulation of memory consolidation for olfactory learning by reversible inactivation of the basolateral amygdala.

    abstract::The role of the basolateral amygdala (BLA) in the consolidation of an association between an olfactory stimulus and footshock was investigated with a reversible lesion technique of post-training intra-BLA infusions of tetrodotoxin. Rats receiving tetrodotoxin infusions following paired odor-shock presentations spent m...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.117.1.184

    authors: Kilpatrick L,Cahill L

    更新日期:2003-02-01 00:00:00

  • Facilitation of fear extinction by midbrain periaqueductal gray infusions of RB101(S), an inhibitor of enkephalin-degrading enzymes.

    abstract::Mu-opioid receptors in the ventrolateral quadrant midbrain periaqueductal gray (vIPAG) contribute to extinction of conditioned fear. The present experiment studied whether fear extinction could be facilitated by infusions of a peptidase inhibitor that reduces catabolism of vIPAG enkephalins. Rats were trained to fear ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.119.6.1672

    authors: McNally GP

    更新日期:2005-12-01 00:00:00

  • Local dopamine production in the dorsal striatum restores goal-directed behavior in dopamine-deficient mice.

    abstract::To determine whether dopamine signaling in the dorsal striatum is sufficient for performance of goal-directed behaviors, local dopamine production was restored in the dorsal striatum of dopamine-deficient (DD) mice through viral-mediated gene therapy. Virally rescued DD (vrDD) mice were tested for learning of an appet...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.120.1.000

    authors: Robinson S,Sotak BN,During MJ,Palmiter RD

    更新日期:2006-02-01 00:00:00

  • Sensitivity to ethanol-induced motor incoordination in 5-HT(1B) receptor null mutant mice is task-dependent: implications for behavioral assessment of genetically altered mice.

    abstract::Neuromuscular impairment by ethanol likely involves complex effects on balance, gait, muscle strength, and other features of motor coordination. The present experiments showed that relative sensitivity to ethanol-induced motor impairment in serotonin 1B (5-HT(1B)) null mutant and control mice was task dependent. We fo...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Boehm SL 2nd,Schafer GL,Phillips TJ,Browman KE,Crabbe JC

    更新日期:2000-04-01 00:00:00

  • Regulation of circadian rhythms in mammals by behavioral arousal.

    abstract::Circadian rhythms in most mammals are synchronized to local time by phase and period resetting actions of daily light-dark cycles on a retino-recipient, light-entrainable circadian pacemaker, the suprachiasmatic nucleus (SCN). The SCN receives input from other brain regions, some of which mediate the phase and period ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章,评审

    doi:10.1037/a0035885

    authors: Webb IC,Antle MC,Mistlberger RE

    更新日期:2014-06-01 00:00:00

  • Tactile stimulation during development attenuates amphetamine sensitization and structurally reorganizes prefrontal cortex and striatum in a sex-dependent manner.

    abstract::This study investigated the effect of postnatal tactile stimulation (TS) on juvenile behavior, adult amphetamine (AMPH) sensitization, and the interaction of TS and AMPH on prefrontal cortical (PFC) thickness and striatum size. Pups received TS by stroking daily with a feather duster from birth till weaning and were t...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0022628

    authors: Muhammad A,Hossain S,Pellis SM,Kolb B

    更新日期:2011-04-01 00:00:00

  • Environmental enrichment as a therapy for autism: A clinical trial replication and extension.

    abstract::Based on work done in animal models showing that autism-like symptoms are ameliorated following exposure to an enriched sensorimotor environment, we attempted to develop a comparable therapy for children with autism. In an initial randomized controlled trial, children with autism who received sensorimotor enrichment a...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章,随机对照试验

    doi:10.1037/bne0000068

    authors: Woo CC,Donnelly JH,Steinberg-Epstein R,Leon M

    更新日期:2015-08-01 00:00:00

  • Involvement of serotonin and oxytocin in neural mechanism regulating amicable social signal in male mice: Implication for impaired recognition of amicable cues in BALB/c strain.

    abstract::Social signals play a primary role in regulating social relationships among male mice. The present series of experiments investigated the neural mechanisms underlying an induction of amicable cues that facilitate social approach in male mice of the C57BL/6 (B6) and BALB/c (BALB) strains. Male mice exhibit approach beh...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/bne0000191

    authors: Arakawa H

    更新日期:2017-04-01 00:00:00

  • Behavioral depression during cocaine withdrawal is associated with decreased spontaneous activity of ventral tegmental area dopamine neurons.

    abstract::Withdrawal from an escalating-dose, bingelike regimen of cocaine administration in rats produced significantly depressed levels of locomotor activity during the nocturnal portion of the day-night cycle. This effect was observed during the first 48 hr of testing. Extracellular single-unit recordings of ventral tegmenta...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.4.860

    authors: Koeltzow TE,White FJ

    更新日期:2003-08-01 00:00:00

  • Lack of task specificity and absence of posttraining effects of atropine on learning.

    abstract::Three experiments are reported whose purpose was to examine the effect of the cholinergic antagonist atropine on the acquisition of different learning tasks known to be sensitive or insensitive to impairment by hippocampal lesions; on the retention of performance acquired in the absence of the drug; and on memory cons...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.100.4.483

    authors: Hagan JJ,Tweedie F,Morris RG

    更新日期:1986-08-01 00:00:00

  • Microinjection of morphine into the nucleus accumbens impairs contextual learning in rats.

    abstract::A unilateral microinjection of morphine into the amygdala impaired fear conditioning to both a conditioned stimulus (CS) paired with shock and the context where shock occurred, whereas a microinjection of morphine into the nucleus accumbens (NA) spared fear conditioning to the CS but impaired, in a dose-dependent and ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.5.996

    authors: Westbrook RF,Good AJ,Kiernan MJ

    更新日期:1997-10-01 00:00:00

  • Premotor cortex in the rat.

    abstract::Donoghue and Wise (1982) identified an area AGm in the rat that they take to be a nonprimary motor area. In the present experiments, therefore, this area was removed bilaterally in rats. The animals were poor at relearning a visual conditional motor task but were able to learn spatial delayed alternation as rapidly as...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.102.1.101

    authors: Passingham RE,Myers C,Rawlins N,Lightfoot V,Fearn S

    更新日期:1988-02-01 00:00:00

  • Opioids and attachment in rhesus macaque (Macaca mulatta) abusive mothers.

    abstract::This study investigated the role of the endogenous opioid system in maternal and affiliative behavior of group-living rhesus macaque (Macaca mulatta) mothers with a history of abusive parenting. Eighteen mothers received an injection of the opioid antagonist naltrexone or saline for 5 days per week for the first 4 wee...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.116.3.489

    authors: Graves FC,Wallen K,Maestripieri D

    更新日期:2002-06-01 00:00:00