Abstract:
:To examine whether the hippocampus is required for memory for unique experiences independent of their spatial or temporal context, the authors devised a novel task that requires rats to remember odor-reward associations formed within a single training trial. Unlike previous tests of 1-trial memory, in this task new associations with otherwise familiar stimuli must be formed, and accurate judgments cannot be based on relative familiarity or recency of the stimuli. The authors show that intact rats performed well on this novel test of event memory. Furthermore, rats with lesions of the hippocampus showed no impairments, even over long retention intervals. These data suggest that the hippocampus is not required for event-specific stimulus-reward associations and that other brain structures mediate this aspect of episodic memory.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Wood ER,Agster KM,Eichenbaum Hdoi
10.1037/0735-7044.118.3.526subject
Has Abstractpub_date
2004-06-01 00:00:00pages
526-39issue
3eissn
0735-7044issn
1939-0084pii
2004-95232-009journal_volume
118pub_type
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
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pub_type: 评论,杂志文章
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