Long-lasting conditioning of the human soleus H reflex following quadriceps tendon tap.

Abstract:

:Percussion of the quadriceps tendon was used to test the hypothesis that knee extensor muscle spindle discharge initiates down-regulation of the gain of the soleus H reflex. Seven subjects participated. Soleus H reflex magnitude was observed for up to 15 s, following conditioning tendon taps of 60 N or 80 N force and 10 ms duration, with the knee at 60 degrees or 90 degrees of flexion. The tap elicited quadriceps stretch reflexes in four subjects, with a mean latency of 42 ms. The major component of the conditioning of the soleus H reflex was significant attenuation of magnitude by 30-90% of controls, starting as early as 36 ms post-percussion and lasting as long as 3-8 s. The attenuation of reflex magnitude was evident, whichever combination of duration and force of tap was used. Preceding and/or following this inhibition, there was mild facilitation. Static stretch of quadriceps also significantly reduced soleus H reflex magnitude. These results support the spindle receptor origin for the gain attenuation seen during movement. The time course of the gain attenuation suggests a spinal route, by which the spindle discharge of the heteronymous extensor muscles initiates presynaptic inhibition of transmission through the reflex pathway.

journal_name

Brain Res

journal_title

Brain research

authors

Cheng J,Brooke JD,Staines WR,Misiaszek JE,Hoare J

doi

10.1016/0006-8993(95)00273-s

subject

Has Abstract

pub_date

1995-05-29 00:00:00

pages

197-200

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(95)00273-S

journal_volume

681

pub_type

临床试验,杂志文章
  • Membrane depolarization and prolongation of calcium-dependent action potentials of mouse neurons in cell culture by two convulsants: bicuculline and penicillin.

    abstract::The convulsant compounds bicuculline (BICUC) and penicillin (PCN) are antagonists of GABA-mediated synaptic inhibition. In addition, we have shown that BICUC and PCN produced membrane depolarization of mouse spinal cord neurons in primary dissociated cell culture by blocking a potassium conductance, a non-synaptic dir...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90609-6

    authors: Heyer EJ,Nowak LM,Macdonald RL

    更新日期:1982-01-28 00:00:00

  • Feeding induced by food deprivation is differentially reduced by G-protein alpha-subunit antisense probes in rats.

    abstract::Antisense oligodeoxynucleotide (AS ODN) probes directed against the alpha-subunit of different G-proteins have been used to differentiate feeding responses in rats elicited by different opioid agonists, including morphine, beta-endorphin and dynorphin. Furthermore, antisense probes directed against G(o)alpha, but not ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(02)03361-9

    authors: Hadjimarkou MM,Silva RM,Rossi GC,Pasternak GW,Bodnar RJ

    更新日期:2002-11-15 00:00:00

  • Immunohistochemical evidence for the localization of neurons containing the putative transmitter L-proline in rat brain.

    abstract::We examined whether there are the neurotransmitter candidate amino acid L-proline containing neurons localized in the rat brain. Antibodies against L-proline conjugated with rabbit serum albumin were raised in a rabbit and purified with affinity chromatography. Strong L-proline-like immunoreactivity was confined to se...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2005.12.064

    authors: Takemoto Y,Semba R

    更新日期:2006-02-16 00:00:00

  • Effects of amyloid-beta on cholinergic and acetylcholinesterase-positive cells in cultured basal forebrain neurons of embryonic rat brain.

    abstract::The neurotoxic effects of amyloid-beta(1-42) and amyloid-beta(25-35) (A beta) on cholinergic and acetylcholinesterase-positive neurons were investigated in primary cultures derived from embryonic 18-day-old rat basal forebrain. After various time intervals, the cultures were treated with 1, 5, 10 or 20 microM A beta f...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2003.11.021

    authors: Kasa P Sr,Papp H,Kasa P Jr,Pakaski M,Balaspiri L

    更新日期:2004-02-13 00:00:00

  • Retardation of resynthesis of GABA-transaminase in some brain regions of amygdala-kindled rats.

    abstract::The activities of GABA-transaminase (GABA-T) were examined in several brain regions of amygdala-kindled rats, pretreated either with or without gabaculine, an irreversible GABA-T inhibitor. Histochemical and biochemical studies demonstrated that GABA-T activities decreased significantly in some brain regions 16 h afte...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90692-x

    authors: Itagaki S,Kimura H

    更新日期:1986-08-27 00:00:00

  • Relationships between hair-follicle afferent terminations and glutamic acid decarboxylase-containing boutons in the cat's spinal cord.

    abstract::Axoaxonic synapses are common features of hair-follicle afferent boutons. We have attempted to discover the identity of the neurotransmitter in the associated axon terminals by combining intra-axonal labelling of hair-follicle afferent axons with immunocytochemistry in a correlated light and electron microscopical stu...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)90394-5

    authors: Maxwell DJ,Noble R

    更新日期:1987-04-07 00:00:00

  • Characterization of blink reflex interneurons by activation of diffuse noxious inhibitory controls in man.

    abstract::The blink reflex consists of an early, pontine R1-component and a late, medullary R2-component. R1 and R2 can be evoked by innocuous stimuli, but only the R2 also by painful heat, suggesting that the R2 is mediated by wide dynamic range neurons (WDR) of the spinal trigeminal nucleus. Remote noxious stimuli suppress th...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)00646-5

    authors: Ellrich J,Treede RD

    更新日期:1998-08-24 00:00:00

  • Hemoglobin as a novel protein developmentally regulated in neurons.

    abstract::We have attempted to identify some novel genes which were found to be more highly expressed in the embryonic brain than in the adult brain. Consequently, one of these clones was identified as alpha-globin cDNA. Actually, alpha-globin mRNA was detected in the neurons. In addition, beta-globin mRNA was detected in the n...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91455-9

    authors: Ohyagi Y,Yamada T,Goto I

    更新日期:1994-01-28 00:00:00

  • Brain tyrosine availability and the depression of central nervous norepinephrine turnover in acute and chronic starvation in adult male rats.

    abstract::Norepinephrine (NE) and 3-methoxy-4-hydroxyphenylglycol (MOPEG) were determined in medio-basal hypothalamus of adult male rats using high-performance liquid chromatography to study nutritional modulation of noradrenergic turnover. Acute starvation, as well as 3 weeks of semistarvation with a low-protein high-carbohydr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90471-8

    authors: Schweiger U,Warnhoff M,Pirke KM

    更新日期:1985-06-03 00:00:00

  • Immediate-early gene expression in cerebral cortex following exposure to chronic-intermittent hypoxia.

    abstract::Chronic-intermittent hypoxia (CIH) was postulated to evoke c-fos expression in cortical regions that modulate sympathetic discharge. Animals exposed to CIH for 30 days exhibited c-fos labeling in medial prefrontal, cingulate, retrosplenial, and insular cortices. Our findings strongly suggest activation of cortical cir...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02170-3

    authors: Sica AL,Greenberg HE,Scharf SM,Ruggiero DA

    更新日期:2000-07-07 00:00:00

  • Concentrations and distribution of vasoactive intestinal peptide (VIP), peptide histidine isoleucine (PHI) and peptide histidine valine (PHV) in the cerebral cortex and the suprachiasmatic nucleus of the mouse.

    abstract::Prepro-vasoactive intestinal peptide (prepro-VIP) is processed to at least three biologically active peptides: VIP, peptide histidine isoleucine (PHI) and an extended PHI, peptide histidine valine (PHV). The aim of the present investigation was by chromatography combined with RIA and immunocytochemistry to determine w...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91370-6

    authors: Mikkelsen JD,Fahrenkrug J

    更新日期:1994-09-05 00:00:00

  • Lysosomal generation of amyloid beta protein species in transgenic mice.

    abstract::Soluble amyloid beta protein (A beta)1-40 and highly amyloidogenic A beta 1-42/43 were immunocytochemically labeled in lysosomes of acinar cells and macrophages in the pancreas of transgenic mice systemically expressing a C-terminal fragment of the A beta precursor. A beta 1-42/43 and long A beta species extending the...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00695-1

    authors: Kawarabayashi T,Igeta Y,Sato M,Sasaki A,Matsubara E,Kanai M,Tomidokoro Y,Ishiguro K,Okamoto K,Hirai S,Shoji M

    更新日期:1997-08-15 00:00:00

  • The electrophysiological and morphological characteristics of feline dorsal root ganglion cells.

    abstract::The electrophysiological characteristics of physiologically typed L7 and S1 dorsal root ganglion (DRG) cells have been studied in the cat by intracellular recording. The injection of the fluorescent dye Lucifer Yellow has enabled us to study the morphology of these neurons. Our results show that over the entire range ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91391-0

    authors: Cameron AA,Leah JD,Snow PJ

    更新日期:1986-01-01 00:00:00

  • Amyloid beta precursor protein-mRNA is expressed throughout cerebral vessel walls.

    abstract::To determine the presence and distribution of cerebrovascular Abeta production we investigated amyloid beta precursor protein (AbetaPP)-mRNA expression by RNA in situ hybridization in patients with hereditary cerebral hemorrhage with amyloidosis, Dutch type, Alzheimer disease and controls. In all subjects, AbetaPP-mRN...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01361-x

    authors: Natté R,de Boer WI,Maat-Schieman ML,Baelde HJ,Vinters HV,Roos RA,van Duinen SG

    更新日期:1999-05-15 00:00:00

  • Evaluation of the periaqueductal central gray (PAG) as a morphine-specific locus of action and examination of morphine-induced and stimulation-produced analgesia at coincident PAG loci.

    abstract::Experiments were carried out in rats to (1) elaborate upon the sepcificity of drug action in the periaqueductal gray matter (PAG), and (2) to evaluate the posible congruence of PAG sites of morphine-induced and stimulation-produced analgesis (SPA) applied at virtually identical PAG loci. It was demonstrated that the e...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(77)90886-1

    authors: Lewis VA,Gebhart GF

    更新日期:1977-03-25 00:00:00

  • Differential pulse voltammetry: simultaneous in vivo measurement of ascorbic acid, catechols and 5-hydroxyindoles in the rat striatum.

    abstract::This paper describes carbon fibre electrodes that can simultaneously monitor changes in ascorbic acid, dihydroxyphenylacetic acid (DOPAC), 5-hydroxyindoleacetic acid (5HIAA) and homovanillic acid (HVA) in vivo in the rat striatum using differential pulse voltammetry. The separation between DOPAC and 5HIAA oxidation is...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)91192-2

    authors: Crespi F,Sharp T,Maidment NT,Marsden CA

    更新日期:1984-11-19 00:00:00

  • Behavioural responses of bicucculline methiodide injections into the ventral hypothalamus of freely moving, socially interacting rats.

    abstract::Several studies, using electrical stimulation of parts of the hypothalamus, have shown, that different parts of the hypothalamus yield different behavioural responses upon stimulation. In order to differentiate between stimulation of neuronal cell bodies and passing fibres and to investigate the role of GABA in hypoth...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91122-9

    authors: Roeling TA,Kruk MR,Schuurmans R,Veening JG

    更新日期:1993-06-25 00:00:00

  • Are hypothalamo-cerebellar fibers collaterals from the hypothalamo-spinal projection?

    abstract::Retrograde transport of fluorescent tracer molecules (Fast Blue and Nuclear Yellow) was used to restudy the feline hypothalamo-cerebellar and hypothalamo-spinal projections in order to decide whether hypothalamo-cerebellar and hypothalamo-spinal fibers are branches of the same axons. The finding of a significant hypot...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)90060-x

    authors: Dietrichs E,Zheng ZH

    更新日期:1984-04-02 00:00:00

  • Enkephalin-containing neurons in substantia gelatinosa of spinal trigeminal complex: ultrastructure and synaptic interaction with primary sensory afferents.

    abstract::The ultrastructural morphology and synaptic associations between enkephalin-containing neurons and sensory afferents was examined in the caudalis portion of rat spinal trigeminal complex, the region corresponding to Rexed's layer II of the dorsal horn. Specific antiserum to Met5-enkephalin was localized by the peroxid...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90580-7

    authors: Sumal KK,Pickel VM,Miller RJ,Reis DJ

    更新日期:1982-09-30 00:00:00

  • beta-Estradiol induces synaptogenesis in the hippocampus by enhancing brain-derived neurotrophic factor release from dentate gyrus granule cells.

    abstract::We investigated the effect of beta-estradiol (E2) on synaptogenesis in the hippocampus using organotypic hippocampal slice cultures and subregional hippocampal neuron cultures. E2 increased the expression of PSD95, a postsynaptic marker, specifically in stratum lucidum of Cornu Ammonis 3 (CA3SL) in cultured hippocampa...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.02.093

    authors: Sato K,Akaishi T,Matsuki N,Ohno Y,Nakazawa K

    更新日期:2007-05-30 00:00:00

  • Calbindin D28k-containing splanchnic and cutaneous dorsal root ganglion neurons of the rat.

    abstract::Calbindin D28k (CaBP)-containing splanchnic and cutaneous sensory neurons in the rat dorsal root ganglia (DRGs) were investigated immunocytochemically in combination with a fluorescent dye tracer (Fluoro gold). About 15% of the DRG neurons at Th9-10 levels showed CaBP-like immunoreactivity. Eighty-four % of the splanc...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91673-5

    authors: Kashiba H,Senba E,Ueda Y,Tohyama M

    更新日期:1990-10-01 00:00:00

  • Mu opioid receptor-containing neurons mediate electroacupuncture-produced anti-hyperalgesia in rats with hind paw inflammation.

    abstract::Previous studies showed that electroacupuncture (EA) significantly attenuates inflammatory hyperalgesia in a complete Freund's adjuvant (CFA)-induced inflammatory pain rat model. The present study demonstrates that pretreatment with Derm-sap, a selective toxin for neurons that contain mu opioid receptor (MOR), specifi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2005.05.008

    authors: Zhang RX,Wang L,Liu B,Qiao JT,Ren K,Berman BM,Lao L

    更新日期:2005-06-28 00:00:00

  • Retarded growth of the suprachiasmatic nucleus and pineal body in dw and lit dwarf mice.

    abstract::The suprachiasmatic nucleus (SCN) and the pineal body in 3 types of inherited hormone-deficient mice, the dw, lit and hyt mice were examined by morphological, morphometric and biochemical techniques. In the dw and lit mice the SCN was underdeveloped. In the ventral part of the SCN, where most of the retinal fibers app...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0165-3806(86)90279-8

    authors: Noguchi T,Sugisaki T,Kudo M,Satoh I

    更新日期:1986-05-01 00:00:00

  • Effects of chronic dizocilpine on acute pain and on mRNA expression of neuropeptides and the dopamine and glutamate receptors.

    abstract::The mesocorticolimbic circuitry has been implicated in the pathophysiology of several neuropsychiatric syndromes like chronic pain and addiction. The aim of this study was to evaluate the effects of dizocilpine (MK-801), a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, on sensorimotor behaviors and t...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(03)02988-3

    authors: Al-Amin HA,Saadé NE,Khani M,Atweh S,Jaber M

    更新日期:2003-08-15 00:00:00

  • Diabetes impairs learning performance and affects the mitochondrial function of hippocampal pyramidal neurons.

    abstract::Previous research has demonstrated that diabetes induces learning and memory deficits. However, the mechanism of memory impairment induced by diabetes is poorly understood. The present study investigated the effect of streptozotocin (STZ)-induced diabetes on spatial learning and memory using the Morris Water Maze. The...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2011.07.011

    authors: Ye L,Wang F,Yang RH

    更新日期:2011-09-09 00:00:00

  • Fluctuation of serum NO(x) concentration at stroke onset in a rat spontaneous stroke model (M-SHRSP). Peroxynitrite formation in brain lesions.

    abstract::Malignant stroke-prone spontaneously hypertensive rats (M-SHRSP) develop hypertension and stroke at earlier ages than do nonmalignant SHRSP. Our previous findings suggested that reactive oxygen species were involved in the development of stroke in this strain. Nitric oxide (NO) which is more released at ischemia, migh...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(02)02975-x

    authors: Tabuchi M,Umegaki K,Ito T,Suzuki M,Tomita I,Ikeda M,Tomita T

    更新日期:2002-09-13 00:00:00

  • Epigenetics and therapeutic targets mediating neuroprotection.

    abstract::The rapidly evolving science of epigenetics is transforming our understanding of the nervous system in health and disease and holds great promise for the development of novel diagnostic and therapeutic approaches targeting neurological diseases. Increasing evidence suggests that epigenetic factors and mechanisms serve...

    journal_title:Brain research

    pub_type: 杂志文章,评审

    doi:10.1016/j.brainres.2015.07.034

    authors: Qureshi IA,Mehler MF

    更新日期:2015-12-02 00:00:00

  • The postnatal development of refractory periods and threshold potentials at cerebellar Purkinje neurons.

    abstract::Cerebellum is involved in the motion coordination and working memory, to which spike programming at Purkinje neurons are essential. The development of Purkinje neurons in the embryonic stage has been well studied. However, it is not clear about the maturation of their intrinsic property related to spike programming du...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.04.092

    authors: Guan S,Ma S,Zhu Y,Wang J

    更新日期:2006-06-30 00:00:00

  • Delayed spontaneous alternation in weaver mutant mice.

    abstract::Weaver mutant mice alternated above chance levels but less often than normal mice in a 2-trial spontaneous alternation test. When the inter-trial (or retention) interval was manipulated, the weaver mutants alternated above chance levels only at the shortest (15 s) but not at the longest (4 or 5 min) intervals, contrar...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91265-5

    authors: Lalonde R

    更新日期:1986-11-19 00:00:00

  • Anxiolytic-like effect of neuropeptide Y (NPY) and NPY13-36 microinjected into vicinity of locus coeruleus in rats.

    abstract::Neuropeptide Y (NPY, 1 and 10 pmol), NPY Y1 receptor agonist [Leu31, Pro34]NPY (10 pmol) and Y2 agonist NPY13-36 (100 pmol) were administered unilaterally into the region of the nucleus locus coeruleus (LC) in rats. NPY (10 pmol) and NPY13-36 increased the percentage of open arm entries, the percentage of time spent o...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)00076-6

    authors: Kask A,Rägo L,Harro J

    更新日期:1998-03-30 00:00:00