Abstract：
:Previous studies showed that electroacupuncture (EA) significantly attenuates inflammatory hyperalgesia in a complete Freund's adjuvant (CFA)-induced inflammatory pain rat model. The present study demonstrates that pretreatment with Derm-sap, a selective toxin for neurons that contain mu opioid receptor (MOR), specifically decreases MOR and blocks EA anti-hyperalgesia. These data suggest that spinal MOR-containing neurons are involved in the processes by which EA produces anti-hyperalgesia.
journal_name
Brain Resjournal_title
Brain researchauthors
Zhang RX,Wang L,Liu B,Qiao JT,Ren K,Berman BM,Lao Ldoi
10.1016/j.brainres.2005.05.008subject
Has Abstractpub_date
2005-06-28 00:00:00pages
235-40issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(05)00719-5journal_volume
1048pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Primary afferent neurons in mammalian dorsal root ganglia (DRGs) normally function as independent sensory communication elements. However, it has recently been shown that most DRG neurons are transiently activated when axons of neighboring neurons of the same ganglion are stimulated repetitively and the cross-depolari...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(03)02342-4
更新日期：2003-04-25 00:00:00
abstract：:The hallucinogen d-lysergic acid diethylamide (d-LSD) evokes dramatic somatic and psychological effects. In order to analyze the neural activation induced by this unique psychoactive drug, we tested the hypothesis that expression of the immediate-early gene product c-Fos is induced in specific regions of the rat foreb...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03548-5
更新日期：2002-12-27 00:00:00
abstract：:After injections of 6-hydroxydopamine (6-OHDA) along the medial forebrain bundle in the lateral hypothalamus, rats failed to acquire a one-way active avoidance response or failed to perform a previously acquired active avoidance response. Such rats, however, acquired a passive avoidance response and a conditioned tast...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(75)90659-9
更新日期：1975-05-09 00:00:00
abstract：:The specific benzodiazepine antagonist, Ro14-7437, in nanomolar concentrations, caused depolarization, increased spontaneous spiking, and conductance decrease when applied to CA1 cells in vitro. These effects were resistant to intracellularly injected Cl- ions or synaptic blockade by TTX, were prevented in Ca2+-free m...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)91370-7
更新日期：1983-07-18 00:00:00
abstract：:To test the hypothesis that presence of metalloproteases (MMPs), their inhibitors (TIMPs) and their substrate laminin-5 differs between the ischemic core and the surrounding tissue, we examined the impact of middle cerebral artery occlusion/reperfusion (MCA:O/R) on these molecules in different regions of the infarct. ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(03)03088-9
更新日期：2003-09-12 00:00:00
abstract：:Ascending and descending projections of the nucleus reticularis gigantocellularis (NRGc) were studied in the cat by the anterograde tracer, Phaseolus vulgaris leucoagglutinin. Ascending fibers from the left or the right NRGc coursed through the bilateral medial reticular formation and some of them reached the dienceph...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)91212-7
更新日期：1988-09-13 00:00:00
abstract：:After traumatic brain injury, extracellular K(+) in brain can dramatically increase. We studied the effects of increased K(+) on the isolated pressurized rat middle cerebral artery (MCA). MCAs (200-250 microm OD) were isolated, cannulated with glass micropipettes, and pressurized. K(+) was increased in the extralumina...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02793-1
更新日期：2000-10-13 00:00:00
abstract：:In albino rats the superior colliculus was stimulated and evoked potentials were explored in the cerebellar hemisphere including the paramedian lobule, and crura I and II. Climbing fiber responses were identified in a strip (ca. 1 mm wide) in the medial region of crus II, extending to both folia a and b. In the tector...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90304-5
更新日期：1986-07-16 00:00:00
abstract：:It has been previously observed that taurine inhibits PKC-activated phosphorylation of specific proteins including a approximately 20k Mr protein in rat cortical synaptosomes. In the present study, the mechanism of the above effects of taurine were investigated. In an intrasynaptosomal cytosol fraction obtained by sub...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90234-m
更新日期：1991-07-05 00:00:00
abstract：:Rat hippocampal slices were perfused with epidermal growth factor (EGF) at a concentration of 10(-8) M. EGF is a well known mitogen which exhibits neurotrophic action on neurons of the CNS. During extra- and intracellular recordings in the pyramidal cell body layer of the CA1-region no influence of EGF on evoked poten...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90380-6
更新日期：1989-04-10 00:00:00
abstract：:Circling training during rat striatum postnatal critical period (PN30 to 37 days) induces a life-lasting co-reduction of muscarinic acetylcholine receptors (mAChR) and dopamine D2 receptors (D2R) binding. Here, we evaluated the expression of D1R and D2R under similar experimental conditions. Trained rats showed a decr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.01.050
更新日期：2004-04-09 00:00:00
abstract：:We examined whether plasma epinephrine contributes to the increase in regional cerebral blood flow (rCBF) evoked by electrical stimulation of the dorsal medullary reticular formation (DMRF). Rats were anesthetized (alpha-chloralose, 30 mg/kg, s.c.), paralyzed and artificially ventilated. The DMRF was electrically stim...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91203-s
更新日期：1990-01-01 00:00:00
abstract：:Lifelong bilingualism is associated with the delayed diagnosis of dementia, suggesting bilingual experience is relevant to brain health in aging. While the effects of bilingualism on cognitive functions across the lifespan are well documented, less is known about the neural substrates underlying differential behaviour...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.02.034
更新日期：2015-07-01 00:00:00
abstract：:Systemic administration of 3-nitropropionic acid (3-NP) results in striatal atrophy by irreversibly inhibiting the citric acid cycle, and thereby resulting in cellular ATP depletion. The neuropathological outcome following 3-NP injections is thought to resemble that seen in Huntington's disease (HD) [1]. The current s...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90085-x
更新日期：1994-05-23 00:00:00
abstract：:The pathogenic mechanisms of gene-environment interactions determining variability of human neurodevelopmental disorders remain unclear. In the two consecutive papers, we used the neonatal Borna disease virus (BDV) infection rat model of neurodevelopmental damage to evaluate brain pathology, monoamine alterations, beh...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02723-3
更新日期：2002-07-19 00:00:00
abstract：:The in vitro model presented provides an approach to study the nature of cell volume control as well as of swelling mechanisms under pathophysiological conditions. Pertinent parameters of cell volume control can be analyzed in isolation due to a virtually infinite extracellular environment precluding secondary effects...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90180-4
更新日期：1983-11-21 00:00:00
abstract：:Experiments were carried out on UC-11MG human astrocytoma cells, a continuous cell line that expresses a broad range of the biochemical and electrophysiological properties found in well-differentiated astrocytes. Because of a number of recent reports that astrocytes may express receptors for a variety of neuro-active ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91676-6
更新日期：1992-10-02 00:00:00
abstract：:The objective was to obtain detailed topographic determinations of cytochrome oxidase activity in the gerbil central auditory system at the light microscopic level. Quantitative techniques were developed using (1) tissue standards calibrated to express histochemical measures as actual enzyme activity units, (2) densit...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90836-2
更新日期：1994-10-10 00:00:00
abstract：:A neuron׳s response to a sound can be suppressed by the presentation of a preceding sound. It has been suggested that this suppression is a direct correlate of the psychophysical phenomenon of forward masking, however, forward suppression, as measured in the responses of the auditory nerve, was insufficient to account...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2016.02.043
更新日期：2016-05-15 00:00:00
abstract：:The effects of unilateral intrahippocampal injections of the non-competitive NMDA receptor antagonist, MK-801, on local cerebral glucose utilisation have been examined in conscious rats using [14C]2-deoxyglucose autoradiography. The intrahippocampal injection of MK-801 (10 nmol) induced significant marked increases in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90995-n
更新日期：1990-06-04 00:00:00
abstract：:To assess the role of androgen-dependent brain vasopressinergic transmission in the modulation of social recognition, castrated male rats which are deficient in vasopressin were implanted intracerebroventricularly with an Accurel collodion mini-device containing 10 micrograms vasopressin (AVP) whereas intact male rats...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90480-w
更新日期：1992-02-14 00:00:00
abstract：:The development of hypertension in spontaneously hypertensive rats (SHR) and hyperactive voiding in rats with urethral obstruction are characterized by abnormal smooth muscle growth, increased tissue levels of nerve growth factor (NGF) and altered patterns of innervation. The present study was undertaken to determine ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00061-4
更新日期：1998-04-20 00:00:00
abstract：:The current experiment aimed to explore age differences in brain activity associated with successful memory retrieval in older adults with different levels of executive functioning, at different levels of task demand. Memory performance and fMRI activity during a recognition task were compared between a young group an...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.10.009
更新日期：2016-01-15 00:00:00
abstract：:The neurophysiological correlates of autoinhibition at the terminals of nigrostriatal dopaminergic neurons were studied by measuring the changes in antidromic excitability of nigrostriatal neurons following local infusions of various catecholamine agonists and antagonists into the neostriatum. Infusions of apomorphine...
journal_title：Brain research
pub_type： 杂志文章
doi：
更新日期：1984-09-10 00:00:00
abstract：:A large body of evidence indicates that both the altered cytokines that mediate the immune-inflammatory process and abnormal gray matter are associated with schizophrenia. Whether peripheral cytokines are related to cerebral structural abnormality remains unclear. Therefore, we aimed to investigate the association of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2019.146463
更新日期：2019-12-01 00:00:00
abstract：:This study was done in urethane anesthetized, ovariectomized (OVX) female rats that were either implanted or not implanted with silastic capsules containing17β-estradiol (E2) to investigate the effect of systemic changes in E2 on the discharge rate of subfornical organ (SFO) neurons that projected to supraoptic nucleu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.06.038
更新日期：2013-08-14 00:00:00
abstract：:A study was undertaken of the role of the external lateral parabrachial subnucleus (PBNLe) in flavor preferences induced by the intragastric administration of predigested/cephalic food. These preferences were developed using two different learning procedures, concurrent and sequential. In the concurrent procedure, two...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03032-9
更新日期：2002-09-20 00:00:00
abstract：:In an effort to further characterize the proteins of the auditory nerve, the effects of hair cell loss on rapidly transported proteins of the auditory nerve were studied. The effects were studied in the waltzing guinea pig, a genetically deaf animal which displays an age-dependent loss of sensory cells, and in normal ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90693-x
更新日期：1982-12-16 00:00:00
abstract：:The medial nucleus of the amygdala, bed nucleus of the stria terminalis, and medial preoptic area appear to mediate steroidal regulation of mating behavior in male rodents. The mechanism of action has not been determined. One way testosterone could enhance neuronal function is by increasing neurotransmitter levels, th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91077-r
更新日期：1992-09-11 00:00:00
abstract：:Inflammatory reactions occurring in the brain after ischemia may contribute to secondary damage. In the present study effects of minocycline, an anti-inflammatory agent, alone or in combination with mild hypothermia, on focal embolic brain ischemia have been examined. Focal ischemic injury was induced by embolizing a ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)04045-3
更新日期：2003-02-14 00:00:00
