Immediate-early gene expression in cerebral cortex following exposure to chronic-intermittent hypoxia.

abstract：:We characterized acute intracerebral hemorrhage (ICH) in the rat by sequential magnetic resonance imaging (MRI) and correlated MRI findings with neurobehavior and histopathology. In addition, we investigated whether albumin treatment would reduce ICH-induced brain injury. ICH was produced in rats by a double-injection...

journal_title：Brain research

authors： Belayev L,Obenaus A,Zhao W,Saul I,Busto R,Wu C,Vigdorchik A,Lin B,Ginsberg MD

更新日期：2007-07-09 00:00:00

abstract：:We investigated the ability of GM1 to induce phosphorylation/activation of the extracellular-regulated protein kinases (ERKs) in the striatum, hippocampus and frontal cortex of aged male Sprague-Dawley rats. Three different treatment paradigms were used: a single application of GM1 to brain slices in situ, a single in...

journal_title：Brain research

authors： Mo L,Ren Q,Duchemin AM,Neff NH,Hadjiconstantinou M

更新日期：2005-08-30 00:00:00

abstract：:We used whole-head magnetoencephalograpy (MEG) to record changes in neuromagnetic N100m responses generated in the left and right auditory cortex as a function of the match between visual and auditory speech signals. Stimuli were auditory-only (AO) and auditory-visual (AV) presentations of /pi/, /ti/ and /vi/. Three t...

journal_title：Brain research

authors： Davis C,Kislyuk D,Kim J,Sams M

更新日期：2008-11-25 00:00:00

abstract：:Thresholds of induction of heat shock protein (HSP) 70 and heat shock cognate protein (HSC) 70 mRNAs after transient global ischemia in gerbil brain were investigated by in situ hybridization using cloned cDNA probes selective for each mRNA species. In sham control brain, HSP70 mRNA was little present, while HSC70 mRN...

journal_title：Brain research

authors： Kawagoe J,Abe K,Kogure K

更新日期：1992-12-25 00:00:00

abstract：:The effect of different steady-state cocaine concentration maintenance on the microdialysis extraction fraction of cocaine (in situ recovery; Ed) in the medial prefrontal cortex (mPFC) was examined. Male, adult Sprague-Dawley rats anesthetized with chloral hydrate were used. All rats were randomly divided into three g...

journal_title：Brain research

authors： Pan WH,Lee JC

更新日期：1995-07-24 00:00:00

abstract：:Brain edema (BE) is an uncommon but life-threatening complication of severe diabetic ketoacidosis (DKA) and its treatment. Despite advances in treatment of DKA, the pathogenesis of both initiation and progression of the associated BE is unclear. In the present study we examined the blood brain barrier (BBB) integrity ...

journal_title：Brain research

authors： Hoffman WH,Stamatovic SM,Andjelkovic AV

更新日期：2009-02-13 00:00:00

abstract：:The melanocortin (MC)4 receptor is important for food intake and weight homeostasis as it mediates the orexigenic and anorexigenic effects of the MCs. OLETF (Otsuka-Long-Evans-Tokushima-Fatty) rats are a selective inbred strain of polygenic variant rats which overeat and develop obesity with elevated leptin levels. We...

journal_title：Brain research

authors： Lindblom J,Schiöth HB,Watanobe H,Suda T,Wikberg JE,Bergström L

更新日期：2000-01-03 00:00:00

abstract：:Ionizing radiations induce oxidative stress on target tissues, mainly through the generation of reactive oxygen species (ROS). However, there are few data available on the behavioral effects of moderate doses of ionizing radiation. The aim of the present work was to evaluate the performance of adult rats irradiated at...

journal_title：Brain research

authors： Caceres LG,Aon Bertolino L,Saraceno GE,Zorrilla Zubilete MA,Uran SL,Capani F,Guelman LR

更新日期：2010-02-02 00:00:00

abstract：:The retinoblastoma protein (pRb) is a key regulator of cell growth, differentiation and survival. pRb(-/-) mice show abnormal neuronal cell death in the developing brain. The function of pRb is regulated by its phosphorylation state. In this study, the phosphorylation of pRb during retinoic acid (RA)-induced neuronal ...

journal_title：Brain research

authors： Watanabe Y,Watanabe T,Kitagawa M,Taya Y,Nakayama K,Motoyama N

更新日期：1999-09-25 00:00:00

abstract：:We have shown previously that progesterone linked with bovine serum albumin at position 3 of the progesterone molecule (P-3-BSA) was effective in modulating (both stimulating and inhibiting) amphetamine (AMPH)-evoked dopamine (DA) release in vitro from superfused corpus striatal (CS) tissue fragments of ovariectomized...

journal_title：Brain research

authors： Dluzen DE,Ramirez VD

更新日期：1991-01-04 00:00:00

abstract：:We have recently demonstrated that the formation of myelin sheaths in the optic nerve of young postnatal mice deficient in the myelin-associated glycoprotein (MAG) is retarded when compared to age-matched wild-type mice. In the present study, we analyzed whether impaired myelination of retinal ganglion cell axons is d...

journal_title：Brain research

authors： Bartsch S,Montag D,Schachner M,Bartsch U

更新日期：1997-07-11 00:00:00

abstract：:We examined the electrophysiological properties of cholinergic and non-cholinergic neurons in the medial septum-diagonal band complex (MSDB) of the rat in the in vitro slice preparation. Cells were identified electrophysiologically, filled with Lucifer yellow, fixed and processed for immunohistochemistry with fluoresc...

journal_title：Brain research

authors： Markram H,Segal M

更新日期：1990-04-09 00:00:00

abstract：:In order to identify fixed versus flexible aspects of swallowing and oromotor control, we developed a method for the concurrent analysis of swallow frequency, swallow volume, and the temporal correlation between swallowing and rhythmic orolingual movements during prolonged bouts of fluid ingestion in unanesthetized, u...

journal_title：Brain research

authors： Kaplan JM,Grill HJ

更新日期：1989-10-09 00:00:00

abstract：:The distribution of cerebellar [3H]flunitrazepam binding sites was studied autoradiographically in Purkinje cell degeneration (pcd/pcd), weaver (wv/wv), staggerer (sg/sg) and reeler (rl/rl) mutant mice. In the normal 78-day-old C57BL/6J mouse cerebellum, the highest concentration of [3H]flunitrazepam binding sites was...

journal_title：Brain research

authors： Rotter A,Frostholm A

更新日期：1988-03-15 00:00:00

abstract：:The lipid, protein, acetylcholine and ATP content of cholinergic synaptic vesicles isolated from the richly innervated electric organ of Torpedo marmorata and purified to constant composition has been determined. The number of vesicles present in the preparations has been estimated by quantitative electron microscopy ...

journal_title：Brain research

authors： Ohsawa K,Dowe GH,Morris SJ,Whittaker VP

更新日期：1979-02-09 00:00:00

abstract：:Angiotensin peptides are thought to act as neurotransmitters or neuromodulators in central osmoregulation. We tested the hypothesis that angiotensin peptides are released in the paraventricular nucleus (PVN) of the hypothalamus upon local osmotic stimulation. Brain microdialysis and radioimmunoassay (RIA) techniques w...

journal_title：Brain research

authors： Qadri F,Edling O,Wolf A,Gohlke P,Culman J,Unger T

更新日期：1994-02-21 00:00:00

abstract：:Spinal nociceptive neural circuits undergo considerable changes during the postnatal period. This study showed that neonatal rats exhibited earlier upregulation and faster recovery of spinal preprodynorphin (PPD) mRNA than did the adults during complete Freund's adjuvant (CFA)-induced peripheral inflammation. These da...

journal_title：Brain research

authors： Zhang RX,Liu B,Lao L,Qiao JT,Ruda MA

更新日期：2005-03-21 00:00:00

abstract：:Striatal D2 dopamine receptor concentrations were shown to decrease 30-35% during the lifespan of Wistar rats as assessed both radiochemically and autoradiographically. Binding densities and degree of age-change varied within the striatum; the latter ranging from 17 to 44% in 4 different regions. Overall neuronal loss...

journal_title：Brain research

authors： Han Z,Kuyatt BL,Kochman KA,DeSouza EB,Roth GS

更新日期：1989-10-02 00:00:00

abstract：:Light microscopic double labeling immunocytochemistry for vasoactive intestinal peptide (VIP) and gonadotrophin-releasing hormone (GnRH) was carried out on the hypothalami of male and female rats. It was found that the number of VIP boutons that terminate on GnRH neurons and the percentage of GnRH neurons contacted by...

journal_title：Brain research

authors： Horvath TL,Cela V,van der Beek EM

更新日期：1998-06-08 00:00:00

abstract：:This study has assessed the neuroprotective efficacy of five AP-1 inhibitory peptides in an in vitro excitotoxicity model. The five AP-1 inhibitory peptides and controls of the JNK inhibitor peptide (JNKI-1D-TAT) and TAT cell-penetrating-peptide were administered to primary cortical neuronal cultures prior to kainic a...

journal_title：Brain research

authors： Meade AJ,Meloni BP,Mastaglia FL,Watt PM,Knuckey NW

更新日期：2010-11-11 00:00:00

abstract：:We previously reported that aquaporin 4 (AQP4) played a critical role in formation of brain edema and the altered expression of dystroglycan (DG) could relate with AQP4 expression after traumatic brain injury (TBI). However the mechanisms of this process remain unclear. DG was showed could act as a scaffold involved i...

journal_title：Brain research

authors： Zhang G,Ma P,Wan S,Xu J,Yang M,Qiu G,Zhuo F,Xu S,Huo J,Ju Y,Liu H

更新日期：2019-10-15 00:00:00

abstract：:We have previously shown that systemic administration of ondansetron, a selective serotonin type-3 (5-HT3) receptor antagonist, attenuates cholecystokinin (CCK)-induced suppression of food intake. The exact location of 5-HT3 receptors mediating this action is not clear and may involve hindbrain 5-HT3 receptors. In thi...

journal_title：Brain research

authors： Hayes MR,Covasa M

更新日期：2006-08-04 00:00:00

abstract：:The newly identified neuropeptide nociceptin/orphanin FQ (NOC) was measured in different rat brain areas related to the descending anti-nociceptive pathways and compared to two opioid peptides, dynorphin B (DYN B) and Met-enkephalinArgPhe (MEAP). Two experimental models of chronic nociception, one neurogenic and one i...

journal_title：Brain research

authors： Rosén A,Lundeberg T,Bytner B,Nylander I

更新日期：2000-02-28 00:00:00

abstract：:Nodes of Ranvier in the central nervous system in mammals are characterized by the presence of perinodal astrocytic processes. This study examines the association between processes of radial glia and the axolemma at nodes of Ranvier in the spinal cord of the mature axolotl, an animal in which radial glia represent a l...

journal_title：Brain research

authors： Sims TJ,Gilmore SA,Waxman SG

更新日期：1991-05-17 00:00:00

abstract：:Experiments were conducted to (1) provide further evidence of the selectivity of [D-Ala2,Leu5,Cys6]enkephalin (DALCE) as an antagonist of delta (delta) receptor ligands and (2) use DALCE as a tool to explore the possible role of delta receptors in restraint stress. Dose- and time-response curves were generated for the...

journal_title：Brain research

authors： Calcagnetti DJ,Bowen WD,Holtzman SG

更新日期：1990-02-19 00:00:00

abstract：:Sardinian alcohol non-preferring (sNP) rats, selected for their low ethanol preference and consumption, carry a point mutation (R100Q) in the gene coding for GABA(A) receptor alpha(6) subunit, which becomes more sensitive to diazepam-evoked GABA currents. We performed binding studies in the cerebellum of normal (RR) a...

journal_title：Brain research

authors： Sanna A,Congeddu E,Porcella A,Saba L,Pistis M,Peis M,Marchese G,Ruiu S,Lobina C,Grayson DR,Gessa GL,Pani L

更新日期：2003-03-28 00:00:00

abstract：:The effects of selective dopamine (DA) depleting lesions with 6-hydroxydopamine microinjection into the SN, CPu, and NAS, as well as radiofrequency lesions of the CPu on the performance characteristics of rats trained on a single-valued 20-s peak-interval (PI) timing procedure or a double-valued 10-s and 60-s PI proce...

journal_title：Brain research

authors： Meck WH

更新日期：2006-09-13 00:00:00

abstract：:Both amphetamine and cocaine lead to an intake pattern in chronic addicts in which the drug is taken repeatedly over prolonged periods. While continuously administered amphetamines, designed to mimic this intake pattern, have a neurotoxic effect on caudate dopamine terminals, several studies have failed to find simila...

journal_title：Brain research

authors： Ellison G

更新日期：1992-12-11 00:00:00

abstract：:Chick neural cultures were used to study effects of insulin, thyrotropin releasing hormone, growth hormone and glucagon on myelin lipid synthesis in vitro. The incorporation of [3H]galactose into myelin associated lipids such as cerebroside and sulfatide was used as an index for various hormonal effects on myelination...

journal_title：Brain research

authors： Kanamoto Y,Karashima H,Kim SU,Eto Y

更新日期：1986-04-16 00:00:00

abstract：:Malignant glioma cells maintain an elevated intracellular pH (pH(i)) within hypoxic-ischemic tumor microenvironments through persistent activation of sodium-proton transport (McLean et al., 2000). Amiloride has been reported to selectively kill human malignant glioma cell lines but not primary astrocytes (Hegde et al....

journal_title：Brain research

authors： Harley W,Floyd C,Dunn T,Zhang XD,Chen TY,Hegde M,Palandoken H,Nantz MH,Leon L,Carraway KL 3rd,Lyeth B,Gorin FA

更新日期：2010-12-02 00:00:00