Electrophysiological characteristics of cholinergic and non-cholinergic neurons in the rat medial septum-diagonal band complex.

abstract：:The aim of this study was to assess the effect of Alzheimer's disease has on the functional integrity of several signal transduction proteins. The relative levels of the G-protein alpha subunits Gs alpha-L, Gs alpha-S, Gi alpha-2 and G(o) alpha were measured by western blotting and found to be unchanged in membranes p...

journal_title：Brain research

authors： Ross BM,McLaughlin M,Roberts M,Milligan G,McCulloch J,Knowler JT

更新日期：1993-09-17 00:00:00

abstract：:Administration of benzodiazepines at appropriate times in the circadian cycle induce phase-shifts in circadian locomotor activity. The possibility that benzodiazepine-induced shifts are mediated at the level of the suprachiasmatic nuclei (SCN), identified as the circadian pacemaker in mammals, was examined electrophys...

journal_title：Brain research

authors： Mason R,Biello SM,Harrington ME

更新日期：1991-06-21 00:00:00

abstract：:Repeated administration of subconvulsant doses of lidocaine or cocaine results in the development of an increased susceptibility to seizures induced by the two drugs (pharmacological kindling). It has been hypothesized that the local anesthetic properties of cocaine are responsible for its convulsant and epileptogenic...

journal_title：Brain research

authors： Marley RJ,Witkin JM,Goldberg SR

更新日期：1991-10-25 00:00:00

abstract：:In order to determine the origin of the catecholamine innervation of the rat piriform cortex (PC), we combined retrograde transport of the B subunit of the cholera toxin (CTb) with tyrosine hydroxylase (TH) immunohistochemistry. A substantial number of CTb retrogradely labeled cells was found in the parabrachial pigme...

journal_title：Brain research

authors： Datiche F,Cattarelli M

更新日期：1996-02-26 00:00:00

abstract：:We have previously found that crocin (crocetin di-gentiobiose ester) antagonizes the inhibitory effect of ethanol on long-term potentiation in the rat hippocampus in vivo and in vitro. To explore mechanisms underlying the antagonism of crocin against ethanol, we investigated the effects of ethanol and crocin on synapt...

journal_title：Brain research

authors： Abe K,Sugiura M,Shoyama Y,Saito H

更新日期：1998-03-16 00:00:00

abstract：:A study of complex I (NADH:ubiquinone oxidoreductase) activity in Parkinson's disease (PD) brain has identified loss of activity only in substantia nigra although loss of activity of this enzyme has been identified in a number of non-brain tissues. We investigated this paradox by studying complex I and other complexes...

journal_title：Brain research

authors： Parker WD Jr,Parks JK,Swerdlow RH

更新日期：2008-01-16 00:00:00

abstract：:Cats acquired a conditioned eyeblink (CR) in a situation where the conditioned stimulus (CS) was a click and the unconditioned stimulus (US) was unilateral electrical stimulation of the zygomatic orbital branch of the facial nerve, which is a motor nerve. In a discrimitive training program, cats received both a click ...

journal_title：Brain research

authors： Black-Cleworth P,Woody CD,Niemann J

更新日期：1975-06-06 00:00:00

abstract：:Of 602 rats tested for amphetamine-induced or nocturnal rotation (circling behavior), 54.8% (P less than 0.025) had right side biases. Of 292 rats tested in two-lever operant situations, 57.5% (P less than 0.02) preferred the right lever. Right-biased rats were significantly more active and had stronger side preferenc...

journal_title：Brain research

authors： Glick SD,Ross DA

更新日期：1981-01-26 00:00:00

abstract：:The effect of lactic acidosis on calcium influx, accumulation and efflux was studied in primary cultures of neonatal cortical rat astrocytes. Treatment of cultures with 20 mM sodium lactate, pH 6.0, for 10-60 min resulted in a 35% reduction of 45Ca2+ influx. The decrease in calcium influx was pH dependent because a si...

journal_title：Brain research

authors： Neary JT,Fu Q,Bender AS,Norenberg MD

更新日期：1993-02-26 00:00:00

abstract：:The volume of nucleus HVc of the avian song system varies greatly both among and within songbird species, and is positively correlated to song complexity in many species. Moreover, the number of neurons in HVc predicts the ability of individual zebra finches to imitate song accurately. To better understand this brain/...

journal_title：Brain research

authors： Ward BC,Nordeen EJ,Nordeen KW

更新日期：2001-06-22 00:00:00

abstract：:Accumulating evidence suggests that dopamine (DA) neurons in the ventral tegmental area (VTA) contribute to the complex amygdala-based neurocircuitry that mediates fear-motivated behaviors. Because of acetylcholine's (ACh) role in DA neuronal activation, the involvement of VTA cholinergic muscarinic receptors in Pavlo...

journal_title：Brain research

authors： Greba Q,Munro LJ,Kokkinidis L

更新日期：2000-07-07 00:00:00

abstract：:This manuscript describes the use of staining of Fos-related antigens (FRAs) as markers for changes in neuronal activity. The model system consisted of the tuberoinfundibular dopamine (TIDA) neurons located in the arcuate nucleus of the hypothalamus. Under normal conditions, these neurons are devoid of c-Fos staining ...

journal_title：Brain research

authors： Hoffman GE,Le WW,Abbud R,Lee WS,Smith MS

更新日期：1994-08-22 00:00:00

abstract：:Behavioral stress is likely to contribute to the development of hypertension in susceptible individuals. We reported that hemodynamic response patterns to acute startle vary and that those patterns predict the predisposition of rats to sustained stress-induced elevations in arterial pressure. Since considerable eviden...

journal_title：Brain research

authors： Tan Y,Gan Q,Knuepfer MM

更新日期：2003-04-04 00:00:00

abstract：:We have evaluated changes in the expression of neurotrophin-3 (NT-3) and its tyrosine kinase C (TrkC) receptor in the neuromuscular system as a result of voluntary physical activity. We assessed changes in the mRNAs and proteins for NT-3 and TrkC in the lumbar spinal cord and associated soleus muscle following 3 and 7...

journal_title：Brain research

authors： Ying Z,Roy RR,Edgerton VR,Gómez-Pinilla F

更新日期：2003-10-10 00:00:00

abstract：:Stimuli such as noise or hypoxia can induce a release of ATP into the cochlear fluid spaces. At nanomolar concentrations, ATP affects neurotransmission and electrochemical regulation of sound transduction. At higher concentrations, ATP may exert cytotoxicity acting on specific P2X(7) receptor subunits, thus contributi...

journal_title：Brain research

authors： Vlajkovic SM,Vinayagamoorthy A,Thorne PR,Robson SC,Wang CJ,Housley GD

更新日期：2006-08-09 00:00:00

abstract：:The behavioral and physiological effects of electrical stimulation of the nucleus locus coeruleus (LC) were studied in the awake rat. LC electrodes consistently supported high rates of self-stimulation (SS). LC stimulation also inhibited spontaneous cellular discharges in the hippocampus (HPC). Both the LC-induced inh...

journal_title：Brain research

authors： Segal M,Bloom FE

更新日期：1976-05-14 00:00:00

abstract：:Milk ejection-related bursts of action potentials recurred at fairly regular intervals during suckling in oxytocin cells of anesthetized lactating rats. Additional milk ejection-related bursts were frequently induced in response to vaginal distension. The latency for the induced response was 2.9 +/- 0.2 s and the size...

journal_title：Brain research

authors： Negoro H,Uchide K,Tadokoro Y,Honda K,Higuchi T

更新日期：1987-02-24 00:00:00

abstract：:Dapsone (4,4'-diaminodiphenylsulfone) is employed in the chemotherapy against leprosy. Dapsone also prevents neuronal damage induced by glutamate agonists. As glutamate excitotoxicity is implicated in the damage after ischemia, we tested the ability of dapsone to prevent ischemic injury in a model of permanent middle ...

journal_title：Brain research

authors： Ríos C,Nader-Kawachi J,Rodriguez-Payán AJ,Nava-Ruiz C

更新日期：2004-03-05 00:00:00

abstract：:Visual acuity was measured by determining the highest spatial acuity at which chickens aged 1-25 days jumped consistently to a physically supported grating instead of to an unsupported homogeneous field. In contrast to the gradual visual development found for kittens, monkeys, and humans, the chicken exhibits asymptot...

journal_title：Brain research

authors： Over R,Moore D

更新日期：1981-05-04 00:00:00

abstract：:Geranylgeranylacetone (GGA), more commonly known as an antiulcer agent, reportedly induces the heat shock protein 70 (HSP70) family in the gastric mucosa, liver and heart of rats. However, it has not been reported whether HSPs, and other factors that contribute to neuroprotection, are inducible in the brain following ...

journal_title：Brain research

authors： Fujiki M,Kobayashi H,Abe T,Ishii K

更新日期：2003-11-21 00:00:00

abstract：:The properties of [3H]dihydropyridine (DHP), nitrendipine and (+)-PN 200-110, binding to rat cerebral membranes were investigated. In normotensive Wistar-Kyoto (WKY) adult rats, the highest densities of [3H]DHP binding sites were found in the hippocampus. Frontal cerebral cortex and hypothalamus had intermediate level...

journal_title：Brain research

authors： Huguet F,Huchet AM,Gerard P,Narcisse G

更新日期：1987-05-26 00:00:00

abstract：:Expertise offers a unique insight into how our brain functions. The purpose of this experiment was to determine if motor system activity and functional connectivity between the cognitive system and sensorimotor system is differentially modulated by an individual's level of expertise. This goal was achieved through the...

journal_title：Brain research

authors： Tomasino B,Maieron M,Guatto E,Fabbro F,Rumiati RI

更新日期：2013-12-02 00:00:00

abstract：:Bilateral lesions of the amygdaloid complex in C57BL/6 mice prevented the occurrence of morphine-induced hypermotility (running fit). This effect, that was different from that observed after hippocampal lesions but similar to that observed after caudate lesions, confirms the role of the basal ganglia catecholaminergic...

journal_title：Brain research

authors： Libri V,Ammassari-Teule M,Castellano C

更新日期：1989-02-06 00:00:00

abstract：:In vivo microdialysis combined with high performance liquid chromatography (HPLC) with electrochemical detection, was used to study the effect of MK-801 (0.1 mg/kg i.p.) on extracellular concentrations of dopamine (DA) 3,4-dihydroxyphenylacetic acid (DOPAC), serotonin (5-HT), norepinephrine (NE) and DOPAC/DA ratio in ...

journal_title：Brain research

authors： Hatip-Al-Khatib I,Mishima K,Iwasaki K,Fujiwara M

更新日期：2001-05-25 00:00:00

abstract：:The effects of hypothermia on caspase-3 activation were investigated in the newborn rat brain after hypoxia-ischemia (HI). Intense caspase-3 activation was observed in the control brains after HI, but this activation was significantly reduced by postischemic hypothermia. These findings suggest that the inhibition of c...

journal_title：Brain research

authors： Fukuda H,Tomimatsu T,Watanabe N,Mu JW,Kohzuki M,Endo M,Fujii E,Kanzaki T,Murata Y

更新日期：2001-08-10 00:00:00

abstract：:The recent indications of specialized lateralization of cardiovascular regulation within the right and left posterior insular cortex of the rat, suggest the possibility of transcallosal connectivity between these regions. This has not been previously demonstrated using physiological techniques. Extracellular neural re...

journal_title：Brain research

authors： Zhang Z,Oppenheimer SM

更新日期：2000-04-28 00:00:00

abstract：:Recently, much attention has focused on the role of the melanocortin system in the regulation of energy homeostasis, especially the satiety effects of the pro-opiomelanocortin (POMC)-derived peptide alpha-melanocyte stimulating hormone (alpha-MSH). We have found that POMC mRNA levels are similar in fat and thin sheep ...

journal_title：Brain research

authors： Henry BA,Rao A,Ikenasio BA,Mountjoy KG,Tilbrook AJ,Clarke IJ

更新日期：2001-11-09 00:00:00

abstract：:The acquisition and retention of tolerance to the antinociceptive effect of supraspinal morphine on the tail withdrawal reflex was assessed in rats implanted with unilateral cannulae in the periaqueductal gray (PAG). Development of tolerance to daily microinjections of morphine was indicated by the return of the tail ...

journal_title：Brain research

authors： Siuciak JA,Advokat C

更新日期：1987-10-27 00:00:00

abstract：:Phosphorylation of cyclic AMP response element binding protein (CREB) is one of the most important mechanisms controlling various gene transcriptions. In the present study, the phosphorylation of CREB was examined immunohistochemically at 24 h of recirculation following 1.5 h of middle cerebral artery occlusion (MCAO)...

journal_title：Brain research

authors： Tanaka K,Nagata E,Suzuki S,Dembo T,Nogawa S,Fukuuchi Y

更新日期：1999-02-13 00:00:00

abstract：:The presence of adrenocorticotropic hormone (ACTH)-immunoreactive cells and melanocortin (MC) receptors (MC4 and to a lesser extent MC3) has been demonstrated in the medullary reticular formation in the general area where rostral ventrolateral medullary pressor area (RVLM) is located. The importance of RVLM in the reg...

journal_title：Brain research

authors： Kawabe T,Chitravanshi VC,Kawabe K,Sapru HN

更新日期：2006-08-02 00:00:00