Astroglial activation accompanies heat shock protein upregulation in rat brain following single oral dose of geranylgeranylacetone.

abstract：:Humans rely on the integration of information from multiple sensory modalities to interact successfully with their environment. In the present series of studies, we investigated how the visuomotor system integrates congruent and incongruent visual and tactile sensory inputs for goal-directed action comprehension and e...

journal_title：Brain research

authors： Kritikos A,Brasch C

更新日期：2008-11-25 00:00:00

abstract：:Heme oxygenase-carbon monoxide-cGMP (HO-CO-cGMP) pathway has been reported to be involved in peripheral and spinal modulation of inflammatory pain. However, the involvement of this pathway in the modulation of acute painful stimulus in the absence of inflammation remains unknown. Thus, we evaluated the involvement of ...

journal_title：Brain research

authors： Carvalho PG,Branco LG,Panissi CR

更新日期：2011-04-18 00:00:00

abstract：:The aim of the present study was to investigate the effects of ischemic preconditioning on infarct volume in a rat model of subdural hematoma (SDH). Ischemic preconditioning was induced by 15 min transient middle cerebral artery (MCA) occlusion followed 3 days later by the injection of 300 microl of autologous venous ...

journal_title：Brain research

authors： Mackay KB,Stiefel TH,Foster AC

更新日期：2002-03-15 00:00:00

abstract：:In view of the use of synthetic propentofylline (PPF) as a protective agent in brain ischemia, its possible side effects on vision capacities have been explored by electroretinography in comparative experiments with theophylline. We used eyecup preparations of small-spotted dogfish sharks and of European eels, particu...

journal_title：Brain research

authors： Andjus RK,Konjević D,Damjanović I,Gacić Z

更新日期：2000-06-23 00:00:00

abstract：:Cortical superfusion with 6-aminomethyl-3-methyl, 1-4H-1,2,6-benzothiadiazine-1,1-diazide hydrocholoride (TAG) at a concentration which selectively blocks taurine (Tau) action fails to modify electroencephalographic (EEG) activity, cortical neuronal firing and caudate-induced inhibition of cortical neuronal activity. ...

journal_title：Brain research

authors： Fariello RG,Golden GT,Ente P

更新日期：1986-08-13 00:00:00

abstract：:We have investigated, in 9 normal subjects, the time course of amplitude changes in the automatic long latency stretch reflex of wrist flexors during the preparatory period as a function of the precued direction of hand movement. Subjects maintained right hand position against a weak force and learned to compensate pr...

journal_title：Brain research

authors： Bonnet M

更新日期：1983-11-28 00:00:00

abstract：:Depolarization by K+ (50 mM) of cultured chick retina cells released 1.14 +/- 0.28% of the accumulated [3H] gamma-aminobutyric acid (GABA) in the absence of Ca2+, but when 1.0 mM Ca2+ was present, the internal free calcium ion concentration [Ca2+]i rose by about 750 nM and the [3H]GABA release about doubled to a value...

journal_title：Brain research

authors： Duarte CB,Ferreira IL,Santos PF,Oliveira CR,Carvalho AP

更新日期：1992-09-18 00:00:00

abstract：:In a focused attention task saccadic reaction time (SRT) to a visual target stimulus (LED) was measured with an auditory (white noise burst) or tactile (vibration applied to palm) nontarget presented in ipsi- or contralateral position to the target. Crossmodal facilitation of SRT was observed under all configurations ...

journal_title：Brain research

authors： Diederich A,Colonius H

更新日期：2008-11-25 00:00:00

abstract：:Partial sciatic nerve ligation in mice caused a marked and persistent decrease in the latency of paw withdrawal from a thermal stimulus only on the ipsilateral side. This thermal hyperalgesia was abolished by repeated intrathecal pretreatment with a specific antibody to brain-derived neurotrophic factor (BDNF), but no...

journal_title：Brain research

authors： Yajima Y,Narita M,Narita M,Matsumoto N,Suzuki T

更新日期：2002-12-27 00:00:00

abstract：:Effects of ketamine on glutamate-induced swelling of astrocytes in primary cell culture were studied. Following the exposure to 1 mM glutamate (Glu) for 4 h the intracellular water space (as measured by 3-O-methyl-[14C]glucose uptake) of astrocytes was increased by two-fold concomitant with cell swelling and disappear...

journal_title：Brain research

authors： Chan PH,Chu L

更新日期：1989-05-22 00:00:00

abstract：:We investigated the responses of putative aortic baroreceptor neurons to mechanical stimulation of their processes. Putative aortic baroreceptor neurons were identified by applying the carbocyanine dye DiI to the adventitia of the aortic arch of anesthetized rats. After at least 1 week, the nodose ganglia were removed...

journal_title：Brain research

authors： Cunningham JT,Wachtel RE,Abboud FM

更新日期：1997-05-16 00:00:00

abstract：:Immunocytochemical localization of specific neurotransmitters in the brain is becoming increasingly important in studies of maturation. We have used the trilaminar prepyriform cortex (PC) of rats to study the distribution, patterns and relative number of cells, fibers and terminals during postnatal development using a...

journal_title：Brain research

authors： Westenbroek RE,Westrum LE,Hendrickson AE,Wu JY

更新日期：1987-08-01 00:00:00

abstract：:Microinjections of the substance P (SP) antagonist (D-pro2,D-phe7,D-trp9)-SP, or the gamma-aminobutyric acid (GABA) agonist, muscimol, into the entopeduncular nucleus reduced muscle tone in genetically spastic rats in a dose- and time-dependent manner. Similar injections into the ventral thalamus, zona incerta or amyg...

journal_title：Brain research

authors： Turski L,Klockgether T,Turski WA,Schwartz M,Sontag KH

更新日期：1990-02-19 00:00:00

abstract：:Stressors produce rapid activation of the hypothalamic-pituitary-adrenal axis, which typically resolves within 60-90 min following termination of the stressor. In addition, some stressors such as inescapable tailshock (IS) also produce elevated basal levels of corticosterone (CORT), and reduced serum levels of cortico...

journal_title：Brain research

authors： Deak T,Nguyen KT,Cotter CS,Fleshner M,Watkins LR,Maier SF,Spencer RL

更新日期：1999-11-20 00:00:00

abstract：:Diabetes mellitus (DM) may lead to gastrointestinal motility disorders. Rodent models of DM indicate the presence of morpho-functional abnormalities of the enteric nervous system. Here, we evaluated whether experimental DM can cause changes in the excitatory cholinergic fibers, neuronal density, and voltage-gated sodi...

journal_title：Brain research

authors： Brasileiro AD,Garcia LP,de Carvalho da Silva S,Rocha LB,Pedrosa AL,Vieira AS,da Silva VJD,Rodrigues ARA

更新日期：2019-04-01 00:00:00

abstract：:Extracellular field recordings were made in CA1 in the hippocampal explant cultures in oxygenated artificial cerebrospinal fluid. Schaffer collaterals were stimulated with 1-s trains of 60 Hz pulses every 10 min. Seizures were reliably elicited with progressive lengthening over 1-2 h. D-APV, an N-methyl-D-aspartate (N...

journal_title：Brain research

authors： Shin C,Tamaki Y,Wilson JT,Butler L,Sakaguchi T

更新日期：1992-08-28 00:00:00

abstract：:Previous work has demonstrated that the GABAergic system is involved in sexual differentiation of the rodent hypothalamus. The present study was designed to further examine this involvement by investigating developmental sex differences in GAD(65) protein levels in hypothalamic and extrahypothalamic brain regions know...

journal_title：Brain research

authors： Perrot-Sinal TS,Davis AM,McCarthy MM

更新日期：2001-12-20 00:00:00

abstract：:The therapeutic effects of dextrorphan and ketamine, two non-competitive N-methyl-D-aspartate (NMDA) receptor antagonists, on neuropathic pain-related behaviors were examined in rats with peripheral mononeuropathy induced by loose ligation of the common sciatic nerve (chronic constrictive injury, CCI). Four daily intr...

journal_title：Brain research

authors： Mao J,Price DD,Hayes RL,Lu J,Mayer DJ,Frenk H

更新日期：1993-03-05 00:00:00

abstract：:The recent development of rodent models of bone cancer pain has started to provide the basis for demonstrating the particular neurochemical and behavioral entity of cancer pain. Behaviourally, both spontaneous pain and hyperalgesia related to mechanical, but not thermal, noxious stimuli have been described in cancer-b...

journal_title：Brain research

authors： Menéndez L,Lastra A,Fresno MF,Llames S,Meana A,Hidalgo A,Baamonde A

更新日期：2003-04-18 00:00:00

abstract：:Electrical stimulation of the sural nerve (SN) revealed input from sural nerve afferents to L6 and L7 dorsal horn neurons that were not apparent using natural mechanical stimuli, especially in cells with variable latency responses to SN stimulation. Nearly all (31/32) cells that had reliable, fixed latency responses t...

journal_title：Brain research

authors： Pubols LM,Foglesong ME,Vahle-Hinz C

更新日期：1986-04-16 00:00:00

abstract：:Ischemic stroke brings a huge family and social burden. Although the reperfusion of ischemic cerebral tissue is the most important way to rescue ischemic stroke, ischemia-reperfusion (I/R) injury further results in brain damage and even lead to death. Recent studies demonstrated that Tongxinluo (TXL) helps to protect ...

journal_title：Brain research

authors： Yu Z,Cai M,Li X,Zhang J,Wu T,Yang F,Zhu W,Xiang Y,Zhang W,Xiang J,Cai D

更新日期：2018-04-15 00:00:00

abstract：:The effect of different dose, mode and duration of estradiol administration was examined in the different brain catecholaminergic areas in ovariectomized (OVX) female rats. We determined changes in mRNA levels of tyrosine hydroxylase (TH), rate-limiting enzyme in catecholamine (CA) biosynthesis of GTP cyclohydrolase I...

journal_title：Brain research

authors： Serova LI,Maharjan S,Huang A,Sun D,Kaley G,Sabban EL

更新日期：2004-07-23 00:00:00

abstract：:The postnatal development of the terminal Schwann cell, an analogue of the lamellar cell in cutaneous sensory receptors, was examined by histochemistry for non-specific cholinesterase and immunohistochemistry for S-100 protein in the periodontal Ruffini endings of the rat incisor. Double immunohistochemistry for S-100...

journal_title：Brain research

authors： Hayashi S,Nakakura-Ohshima K,Ohshima H,Noda T,Honma S,Wakisaka S,Maeda T

更新日期：2000-03-06 00:00:00

abstract：:Choline molecules are needed for the synthesis of acetylcholine and phospholipids in the mammalian brain. An enzymatic activity capable of forming lecithin (phosphatidylcholine) from the step-by-step methylation of phosphatidylethanolamine is identified in the bovine brain. This enzyme(s), phosphatidylethanolamine-N-m...

journal_title：Brain research

authors： Blusztajn JK,Zeisel SH,Wurtman RJ

更新日期：1979-12-28 00:00:00

abstract：:Cholinergic mechanisms in the septohippocampal pathway contribute to several cognitive functions and impaired cholinergic transmission in this pathway may be related to the memory loss and dementia that accompanies normal aging and Alzheimer's disease and behavioral studies suggest that muscarinic mechanisms in the me...

journal_title：Brain research

authors： Liu W,Kumar A,Alreja M

更新日期：1998-09-14 00:00:00

abstract：:Zebrafish as a neurogenetic model system depends on the correct neuroanatomical understanding of its brain organization. Here, we address the unresolved question regarding a possible zebrafish homologue of the dorsal pallial division, the region that in mammals gives rise to the isocortex. Analyzing the distributions ...

journal_title：Brain research

authors： Mueller T,Dong Z,Berberoglu MA,Guo S

更新日期：2011-03-24 00:00:00

abstract：:The metabolic effects of intravenous administration of 200 mg/kg imidazole-4-acetic acid (IMA) on normoxic, hypoxemic and hypoxemic-oligemic rat brain were assessed by measurement of the cerebral contents of energy phosphates and selected glycolytic-citric acid cycle intermediates. In normoxic brain IMA was associated...

journal_title：Brain research

authors： MacMillan V

更新日期：1982-01-28 00:00:00

abstract：:In this study we investigated the functional connectivity in 23 Mild TBI (mTBI) patients with and without memory complaints using resting state fMRI in the sub-acute stage of injury as well as a group of control participants. Results indicate that mTBI patients with memory complaints performed significantly worse than...

journal_title：Brain research

authors： Sours C,Zhuo J,Janowich J,Aarabi B,Shanmuganathan K,Gullapalli RP

更新日期：2013-11-06 00:00:00

abstract：:Hypoxia preconditioning states that a sublethal hypoxia period will afford neuroprotection against a second harmful event. In our experiments, we carried out a procedure for the development of hypoxia preconditioning in adult male Wistar rats using hypoxic exposure (9% O(2); 91% N(2)) for 1 h. The protection against p...

journal_title：Brain research

authors： Rauca C,Zerbe R,Jantze H,Krug M

更新日期：2000-06-16 00:00:00

abstract：:We previously reported that brain angiotensin II type 2 (AT2) receptors contribute to the hyperthermia induced by intrahypothalamic (intrapreoptic (i.p.o.)) administration of prostaglandin E2 (PGE2) in rats. The present study was carried out to investigate the role of angiotensin II (ANG II) receptors in the cardiovas...

journal_title：Brain research

authors： Watanabe T,Sakata Y,Wada M

更新日期：2000-01-03 00:00:00