The entopeduncular nucleus regulates muscle tone in genetically spastic rats: role of substance P and gamma-aminobutyric acid.

abstract：:We measured the effect of high PCO (500-550 Torr) on the pHi and [Ca2+]i in cultured glomus cells of adult rat carotid body (CB) as a test of the two models currently proposed for the mechanism of CB chemoreception. The metabolic model postulates that the rise in glomus cell [Ca2+]i, the initiating reaction in the sig...

journal_title：Brain research

authors： Mokashi A,Roy A,Rozanov C,Osanai S,Storey BT,Lahiri S

更新日期：1998-08-24 00:00:00

abstract：:Effects of lateral vestibular nucleus (LVN) stimulation on neuronal activity in the rat lateral hypothalamic area (LHA), including specific glucose-sensitive neurons, were investigated by extracellular and intracellular recordings in vivo. Stimulation of the contralateral LVN evoked 3 types of response in 46% (111/240...

journal_title：Brain research

authors： Katafuchi T,Puthuraya KP,Yoshimatsu H,Oomura Y

更新日期：1987-01-01 00:00:00

abstract：:The research question was, do events arising from rhythmic passive movement of the human leg lead to inhibition of the H reflex pathway in the stationary leg contralateral to that movement? Further, as the angular velocity of the passive movement increases, does the contralateral reflex inhibition also increase? Stabl...

journal_title：Brain research

authors： Collins DF,McIlroy WE,Brooke JD

更新日期：1993-02-12 00:00:00

abstract：:A startle-like response can be evoked at low currents by one-pulse electrical stimulation of reticular formation sites from the rostrolateral pons to the caudomedial medulla. To test whether this response is mediated by the same reticular formation neurons as those that mediate the acoustic startle, we delivered a bri...

journal_title：Brain research

authors： Yeomans JS,Cochrane KA

更新日期：1993-07-23 00:00:00

abstract：:Movements of medium and large sized membranous organelles (0.5-1 microns in diameter) were visualized within segments of the crab walking leg nerve with Nomarski differential interference contrast optics and subjected to video contrast enhancement. Accessibility to the axoplasm was demonstrated by intra-axonal fluores...

journal_title：Brain research

authors： Moshiach S,Nelson TJ,Sanchez-Andres JV,Sakakibara M,Alkon DL

更新日期：1993-03-12 00:00:00

abstract：:The axonal transport of radiolabeled slow phase proteins and fast phase glycoproteins was studied in rabbit hypoglossal nerve one week after axotomy. The nerves were ligated and cut to prevent axonal regeneration into the distal stump. In this situation of obstructed axonal outgrowth, the axonal transport of these com...

journal_title：Brain research

authors： Frizell M

更新日期：1982-10-28 00:00:00

abstract：:The role of N-methyl-D-aspartate (NMDA) receptors in specific D1 and D2 regulation of striatal and accumbens neurotensin (NT) systems was investigated. As demonstrated previously, stimulation of D1 receptors with multiple administrations of SKF 38393 significantly increased striatal and accumbens NT content to approxi...

journal_title：Brain research

authors： Singh NA,Bush LG,Gibb JW,Hanson GR

更新日期：1992-02-07 00:00:00

abstract：:Binding activities specific for each of [3H]prostaglandin (PG) D2, E2 and F2 alpha were detected in the P2 fraction of the human brain homogenates. The bindings were time-dependent, saturable and of high affinity; Kd values were 30 nM for all the PG bindings. Regional distribution of these binding activities was deter...

journal_title：Brain research

authors： Watanabe Y,Tokumoto H,Yamashita A,Narumiya S,Mizuno N,Hayaishi O

更新日期：1985-09-02 00:00:00

abstract：:Recent studies suggest that apolipoprotein E (apoE) might play a neurotrophic function in the central nervous system and that altered functioning of this molecule could result in neurodegeneration. The main objective of this study was to determine if neurodegenerative and cognitive alterations in apoE-deficient mice a...

journal_title：Brain research

authors： Masliah E,Samuel W,Veinbergs I,Mallory M,Mante M,Saitoh T

更新日期：1997-03-21 00:00:00

abstract：:In a previous companion paper [Brain Res. 846 (1999) 87-105] we have shown that the dorsal root activity of a decerebrate cat is composed of both orthodromic and antidromic discharges as determined by spike triggered averaging (STA). Furthermore we have shown that, during fictive locomotion in decerebrate and paralyze...

journal_title：Brain research

authors： Beloozerova IN,Rossignol S

更新日期：2004-01-23 00:00:00

abstract：:Recent physiological evidence indicates that vagal postganglionic control of left ventricular contractility is mediated by neurons found in a ventricular epicardial fat pad ganglion. In the dog this region has been referred to as the cranial medial ventricular (CMV) ganglion [J.L. Ardell, Structure and function of mam...

journal_title：Brain research

authors： Massari VJ,Dickerson LW,Gray AL,Lauenstein JM,Blinder KJ,Newsome JT,Rodak DJ,Fleming TJ,Gatti PJ,Gillis RA

更新日期：1998-08-17 00:00:00

abstract：:The blood-brain barrier (BBB) restricts solute permeability across healthy cerebral endothelial cells. However, during inflammation, permeability is increased and can lead to deleterious cerebral edema. Neutrophils are early cellular participants in acute inflammation, but their effect on BBB permeability is unclear. ...

journal_title：Brain research

authors： Joice SL,Mydeen F,Couraud PO,Weksler BB,Romero IA,Fraser PA,Easton AS

更新日期：2009-11-17 00:00:00

abstract：:We compared the effect of mecamylamine and fluoxetine on the hippocampal noradrenaline (NA) release evoked by nicotine in vitro. Nicotine (100 microM) increased the basal release of [3H]NA from rat hippocampal slices. This effect was blocked by the potent nicotinic antagonist mecamylamine in a dose-dependent manner (I...

journal_title：Brain research

authors： Hennings EC,Kiss JP,Vizi ES

更新日期：1997-06-13 00:00:00

abstract：:Post traumatic stress disorder (PTSD) is characterised by hyperarousal, anxiety and amnesic symptoms. Deficits in explicit memory recall have been causally related to volume reductions of the hippocampus and prefrontal cortex. While stress-related glucocorticoid secretion appears involved in this apparent atrophy, the...

journal_title：Brain research

authors： Harvey BH,Naciti C,Brand L,Stein DJ

更新日期：2003-09-05 00:00:00

abstract：:The solitary tract nucleus (NTS) is the termination site for cranial visceral afferents-peripheral primary afferent neurons which differ by phenotype (e.g. myelinated and unmyelinated). These afferents have very uniform glutamate release properties calculated by variance mean analysis. In the present study, we optical...

journal_title：Brain research

authors： Jin YH,Cahill EA,Fernandes LG,Wang X,Chen W,Smith SM,Andresen MC

更新日期：2010-02-02 00:00:00

abstract：:Mild footshock stress results in the metabolic activation of the prefrontal cortical dopamine (DA) innervation, but does not augment DA utilization in mesolimbic areas (such as the nucleus accumbens septi, NAS) or the striatum. However, increases in either the intensity or duration of footshock stress increase DA util...

journal_title：Brain research

authors： Deutch AY,Clark WA,Roth RH

更新日期：1990-06-25 00:00:00

abstract：:The purpose of this paper is to investigate the involvement of various auditory localization mechanisms in the improvement of auditory spatial sensitivity in the case of partial visual deprivation. We compared sensitivity to binaural, monaural, and echo cues between normal-sighted and myopic subjects. In an auditory t...

journal_title：Brain research

authors： Després O,Candas V,Dufour A

更新日期：2005-04-11 00:00:00

abstract：:Male and female hooded rats were raised from weaning in either a complex or an isolated environment in two separate replications. After one month, the brains were Golgi-Cox stained and dendritic fields of dentate gyrus granule cells were quantified. There was a sex difference in response to the environment. Females ra...

journal_title：Brain research

authors： Juraska JM,Fitch JM,Henderson C,Rivers N

更新日期：1985-04-29 00:00:00

abstract：:To determine whether the idiosyncratic distribution of transduction mechanisms for bitter tastants in rat taste receptor cells (TRCs) could be inferred from the neural activity they evoke, single neuron responses to ten bitter-tasting compounds were recorded from rat glossopharyngeal (n = 30) and chorda tympani (n = 2...

journal_title：Brain research

authors： Dahl M,Erickson RP,Simon SA

更新日期：1997-05-09 00:00:00

abstract：:Although nitric oxide (NO) has been shown to play an important role in the pathophysiology of cerebral ischemia, its contribution to the pathogenesis of experimentally induced thromboembolic stroke is unknown. In this study, we pharmacologically manipulated NO levels in the acute post-thrombotic stage and determined t...

journal_title：Brain research

authors： Stagliano NE,Dietrich WD,Prado R,Green EJ,Busto R

更新日期：1997-06-06 00:00:00

abstract：:Data from several laboratories indicate that cerebral endothelial cells possess cell surface receptors for numerous vasoactive agents including angiotensin II (AII) and atrial natriuretic factor (ANF). The intracellular messengers of these receptors as well as possible receptor interactions were explored. ANF increase...

journal_title：Brain research

authors： Grammas P,Giacomelli F,Bessert D,Wiener J

更新日期：1991-10-18 00:00:00

abstract：:Chemical synaptic transmission was studied with microelectrode techniques in isolated frog cerebella maintained in vitro. Purkinje cell (PC) EPSPs, elicited by selective monosynaptic electrical stimulation of both the parallel fiber (PF) and climbing fiber (CF) inputs, could be inverted by depolarizing (outward) curre...

journal_title：Brain research

authors： Hackett JT

更新日期：1976-09-10 00:00:00

abstract：:The cytoplasmic adaptor protein Disabled-1 (Dab1), which is a key component of the Reelin-signaling pathway, has been suggested to be required for neuronal dendritic development. However, only data from studies on immature cultures [< or = 6 days in vitro (DIV)] and cytoarchitectural analyses of mutant mice have been ...

journal_title：Brain research

authors： MacLaurin SA,Krucker T,Fish KN

更新日期：2007-10-03 00:00:00

abstract：:5-Hydroxytryptamine (5-HT, serotonin), synthesized in midbrain raphe nuclei and released in various hypothalamic sites, decreases food intake but the specific 5-HT receptor subtypes involved are controversial. Here, we have studied changes in the regional density of binding to 5-HT receptors and transporters and the l...

journal_title：Brain research

authors： Park S,Harrold JA,Widdowson PS,Williams G

更新日期：1999-11-13 00:00:00

abstract：:A normobar hypoxia (9% oxygen) of 8 h reduces the neurotoxicity of a subcutaneous injection of 10 mg/kg kainic acid given one week later. Both seizures and degenerative changes, including cell death of hippocampal and cortical neurons are markedly decreased by hypoxia. It is also shown that hypoxia also markedly reduc...

journal_title：Brain research

authors： Pohle W,Rauca C

更新日期：1994-05-02 00:00:00

abstract：:Previous research has demonstrated that cross-language activation is present even when proficient bilinguals perform a task only in one language. The present study investigated the time-course of cross-language activation during word production in a second language (L2) by using a picture-word interference paradigm wi...

journal_title：Brain research

authors： Hoshino N,Thierry G

更新日期：2011-01-31 00:00:00

abstract：:Individual neurons were recorded extracellularly in the nucleus accumbens (NAcc) of rats during cocaine self-administration sessions. NAcc neurons exhibited a variety of phasic changes in firing rate within the few seconds before and/or after cocaine self-infusion. Analysis of the topographical distribution of the pha...

journal_title：Brain research

authors： Uzwiak AJ,Guyette FX,West MO,Peoples LL

更新日期：1997-09-05 00:00:00

abstract：:Previous work, using membrane receptor binding techniques, demonstrated an increase in hippocampal MK-801 binding sites in mice after chronic ethanol ingestion. The current studies, using quantitative autoradiography, demonstrate that chronic ethanol ingestion also produces increases in MK-801 binding in cerebral cort...

journal_title：Brain research

authors： Gulya K,Grant KA,Valverius P,Hoffman PL,Tabakoff B

更新日期：1991-04-26 00:00:00

abstract：:The regulation of spike generation in rat midbrain dopamine (DA) neurons was investigated using in vitro intracellular recordings. DA neurons fired long (greater than 1.8 ms) action potentials that exhibited comparatively depolarized spike thresholds (approx. -35 to -45 mV). Depolarization of the DA neuron increased t...

journal_title：Brain research

authors： Grace AA

更新日期：1990-07-30 00:00:00

abstract：:The effect of intrathecal (i.t.) galanin (GAL) on the prolonged increase of spinal reflex excitability produced by conditioning stimulation (CS) of unmyelinated muscle afferents was studied in decerebrate, spinalized, unanesthetized rats. A CS train (1 Hz, 20 s) applied to the unmyelinated fibers in the gastrocnemius ...

journal_title：Brain research

authors： Xu XJ,Wiesenfeld-Hallin Z,Hökfelt T

更新日期：1991-02-15 00:00:00