Abstract:
:Male and female hooded rats were raised from weaning in either a complex or an isolated environment in two separate replications. After one month, the brains were Golgi-Cox stained and dendritic fields of dentate gyrus granule cells were quantified. There was a sex difference in response to the environment. Females raised in the complex environment had more dendrite per neuron than females from the isolated environment in both replications. This difference was evident chiefly in the length of dendritic branches. Males showed few differences in response to the environments in either replication and, to the extent that there were differences, there was a slight tendency for isolated males to have more dendrite per neuron than males from the complex environment. In comparisons between the sexes within an environment, males had more dendritic material per neuron than females in the isolated environment while females had a larger dendritic tree than males in the complex environment. The above pattern of differences was not altered when hemisphere or location of the cell body within the granule cell layer were taken into account, although the shape of the dendritic tree varied with the cell's position in the layer in all groups. Thus, females show greater structural change in the dentate granule cells in response to these environments than do males.
journal_name
Brain Resjournal_title
Brain researchauthors
Juraska JM,Fitch JM,Henderson C,Rivers Ndoi
10.1016/0006-8993(85)90125-8subject
Has Abstractpub_date
1985-04-29 00:00:00pages
73-80issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(85)90125-8journal_volume
333pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::PC12D cells, a subline of PC12 cells, extend neurites very rapidly in response to NGF, even when RNA synthesis is blocked. Several minutes after the initiation of a concentration gradient of NGF from a micropipette in the vicinity of PC12D cells, clear projections emerged from cells on the side facing the micropipette...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91387-0
更新日期:1994-09-05 00:00:00
abstract::A study was undertaken of the role of the external lateral parabrachial subnucleus (PBNLe) in flavor preferences induced by the intragastric administration of predigested/cephalic food. These preferences were developed using two different learning procedures, concurrent and sequential. In the concurrent procedure, two...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)03032-9
更新日期:2002-09-20 00:00:00
abstract::A substantial number of patients do not respond sufficiently to antidepressant drugs and are therefore often co-medicated with lithium as an augmentative strategy. Since lithium has been demonstrated to affect 5-HT neurotransmission, we examined the effect of acute and subchronic lithium on 5-HT levels after a challen...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02461-6
更新日期:2000-07-21 00:00:00
abstract::Interhemispheric connections were studied by injecting a mixture of horseradish peroxidase (HRP) and wheatgerm agglutinin conjugated with horseradish peroxidase (WGA-HRP) into multiple sites in dorsolateral occipital and parietal cortex of one cerebral hemisphere of three galagos (Galago crassicaudatus) and two owl mo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90680-7
更新日期:1994-07-18 00:00:00
abstract::Aluminum (Al) concentrations of the rat frontal cortex, parietal cortex, and hippocampus were measured by atomic absorption spectroscopy 16 days after a unilateral intracerebroventricular injection of Na gluconate, Al gluconate, or the cholinotoxin AF64A. A fourth group of rats were injected with AF64A 6 days before i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90946-8
更新日期:1988-03-22 00:00:00
abstract::L-Tryptophan produces a significant antihypertensive effect in spontaneously hypertensive rats while D-tryptophan does not change blood pressure. Both isomers of tryptophan significantly increase brain serotonin to the same extent at a time when the antihypertensive effect of L-tryptophan is maximal. Thus, the antihyp...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90985-5
更新日期:1984-03-19 00:00:00
abstract::Erythropoietin (EPO) provides neuroprotection and neurorestoration after traumatic brain injury (TBI). The EPO doses used for treatment of TBI significantly increase hematocrit, which may affect the efficacy of EPO therapy for TBI. The aim of this study was to investigate whether normalization of hematocrit would affe...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.07.077
更新日期:2009-10-19 00:00:00
abstract::Dapsone (4,4'-diaminodiphenylsulfone) is employed in the chemotherapy against leprosy. Dapsone also prevents neuronal damage induced by glutamate agonists. As glutamate excitotoxicity is implicated in the damage after ischemia, we tested the ability of dapsone to prevent ischemic injury in a model of permanent middle ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2003.11.040
更新日期:2004-03-05 00:00:00
abstract::The basic characteristics of the electroencephalograms (EEGs) of the entorhinal cortex (EC) were compared to those of the olfactory bulb (OB) and prepiriform cortex (PPC) in the awake cat, using methods that take into account linear (coherence functions) and non-linear relationships (mutual information). The frequency...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91264-4
更新日期:1988-05-17 00:00:00
abstract::In zebra finches, androgens stimulate song production and promote growth of the neural regions controlling song. Early exposure to estrogen establishes this sensitivity to androgens and increases the number of androgen-accumulating cells in two song regions, the hyperstriatum ventralis pars caudalis (HVc) and the magn...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90715-4
更新日期:1989-05-29 00:00:00
abstract::The non-toxic neuronal binding domain of tetanus toxin (tetanus toxin fragment C, TTC) has been used as a vector to enhance delivery of potentially therapeutic proteins to motor neurons from the periphery following an intramuscular injection. The unique binding and transport properties of this 50-kDa polypeptide sugge...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.03.007
更新日期:2004-06-11 00:00:00
abstract::Previous work has shown that bilateral injection of as little as 10 microgram of cycloheximide (CHX) into the amygdala, but not into the internal capsule, caused a time-dependent disruption of long-term retention of passive avoidance training. Under these conditions, protein synthesis in the entire brain was inhibited...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)91178-1
更新日期:1981-03-23 00:00:00
abstract::Purkinje cell degeneration (pcd) mutant mice lose virtually all Purkinje cells. It was found that the pcd mutants did not show within-sessions habituation in terms of hole-poking responses. This type of perseverative responding has been found in rats with limbic system damage and implies a role for the cerebellum in b...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91354-1
更新日期:1989-02-06 00:00:00
abstract::Long-term potentiation (LTP) is a form of synaptic plasticity that may underlie learning and memory. The experiments reported here demonstrate that cocaine blocks the induction of LTP at the excitatory synapses in the CA1 region of the hippocampus, but does not appear to do so by blocking NMDA receptors or channels. O...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91466-6
更新日期:1993-04-16 00:00:00
abstract::During the middle of the subjective day, circadian activity rhythms in Syrian hamsters can be phase advanced by a variety of stimuli including microinjection of neuropeptide Y (NPY) or muscimol into the suprachiasmatic nucleus (SCN). It is not known, however, if these treatments shift activity rhythms by acting direct...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)00831-7
更新日期:1997-10-24 00:00:00
abstract::The properties of 5 beta-reductase, 5 alpha-reductase and aromatase, 3 testosterone metabolizing enzymes, were studied in the quail brain by an in vitro incubation technique. The results describe the changes in time of metabolite production and the effects of temperature, enzyme and cofactor concentrations. The appare...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)91118-1
更新日期:1984-07-02 00:00:00
abstract::Neuropathic pain remains a major complication of various forms of injury to peripheral nerves in humans. Recently, 2 models of peripheral mononeuropathy in the rat have been described which closely resemble the human condition. Bennett and Xie3 described one model induced by the placement of 4 loose ligatures around t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90570-y
更新日期:1992-01-20 00:00:00
abstract::The jimpy gene is a sex-linked recessive mutation which produces severe hypomyelination throughout the central nervous system (CNS) in affected male mice. The female carrier also expresses the mutation, but the degree of hypomyelination varies considerably among the tracts. In the optic nerve, patches of unmyelinated ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90958-1
更新日期:1982-10-28 00:00:00
abstract::While listening to music, we immediately detect 'wrong' tones that do not match our expectations based on the prior context. This study aimed to determine whether such expectations can occur preattentively, as indexed by event-related potentials (ERPs), and whether these are modulated by attentional processes. To this...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.08.023
更新日期:2006-10-30 00:00:00
abstract::The Reelin signaling pathway controls radial neuronal migration and maturation in the developing brain. The platelet activating factor (PAF) acetyl hydrolase 1b (Pafah1b) complex is also involved in multiple aspects of brain development. We previously showed that the Reelin pathway and the Pafah1b complex interact gen...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.02.059
更新日期:2009-04-24 00:00:00
abstract::Brevetoxins (PbTx) are potent allosteric enhancers of voltage-gated sodium channel (VGSC) function and are associated with periodic "red tide" blooms. These neurotoxins produce neuronal injury and death in cerebellar granule cells (CGC) following acute exposure. In murine neocortical neurons, brevetoxin induces Ca(2+)...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.10.018
更新日期:2005-01-07 00:00:00
abstract::Recent studies suggest that 3-hydroxy-3 methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, statins, can have direct effects on blood vessels beyond their cholesterol-lowering effects. We investigated the effects of atorvastatin on the functional and structural properties of blood-brain barrier (BBB) and the act...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.02.044
更新日期:2005-05-03 00:00:00
abstract::Histopathological changes induced by intrahippocampal injections of low doses of kainic acid (17.5 ng/site) were investigated in rats. Kainic acid produced a selective loss of CA3 pyramidal and hilar neurons. The development of kainic acid-induced neuronal injury was not accompanied by any detectable loss of histologi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91050-5
更新日期:1988-05-24 00:00:00
abstract::Traumatic brain injury (TBI) is one of the largest health problems in the United States and affects both cognitive and motor function. Although weakness is common in TBI patients, few studies have demonstrated a reduction in strength in models of brain injury. We have developed a behavioral method to measure volitiona...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2014.07.039
更新日期:2014-09-25 00:00:00
abstract::A monospecific antibody against tyrosine hydroxylase (TH), purified from a transplantable rat pheochromocytoma, was produced in rabbits. Immunohistochemical techniques were employed in order to determine if a relationship exists between the subcellular distribution of TH and the level of activation of the enzyme in th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90158-x
更新日期:1981-03-30 00:00:00
abstract::The effects of selective dopamine antagonists on the pentazocine-like discriminative stimulus effects of morphine were investigated in the rat trained to discriminate 3.0 mg/kg of pentazocine from vehicle. Morphine (3.0 mg/kg), a mu-selective agonist, produced stimulus effects in common with pentazocine (3.0 mg/kg), i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91088-i
更新日期:1991-02-08 00:00:00
abstract::Within the framework of the dual process model of recognition memory, prior work with event-related potentials (ERPs) has suggested that an early component, the FN400, is a correlate of familiarity while a later component, the Late Positive Complex (LPC), is a correlate of recollection. However, other work has questio...
journal_title:Brain research
pub_type: 临床试验,杂志文章
doi:10.1016/j.brainres.2006.04.050
更新日期:2006-06-22 00:00:00
abstract::We previously reported that the antinociceptive effect of morphine on the thermal tail withdrawal reflex (tail flick, TF) was reduced in rats that had practiced the TF response prior to morphine administration. This phenomenon, termed behavioral tolerance, was observed even when rats were spinally transected following...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90342-7
更新日期:1992-05-22 00:00:00
abstract::In the present study, we report the localization of the Rev-ErbA alpha and beta nuclear orphan receptors, two closely related members of the nuclear hormone receptor superfamily, in the brain. Both Rev-ErbA variant mRNAs were highly expressed in the olfactory bulb, the hippocampus, and in the granular cells of the cer...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(96)00507-0
更新日期:1996-12-16 00:00:00
abstract::The present study was undertaken to disclose temporal changes in the distribution of Fos-like immunoreactive (-IR) neurons in the trigeminal subnucleus caudalis (SpVc), one of the important relay nuclei for processing the nociceptive information from the oro-facial regions, following induction of experimental tooth mo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)01323-7
更新日期:1999-02-20 00:00:00