Intraventricular administration of the cholinotoxin AF64A increases the accumulation of aluminum in the rat parietal cortex and hippocampus, but not in the frontal cortex.

abstract：:Hypoxia preconditioning states that a sublethal hypoxia period will afford neuroprotection against a second harmful event. In our experiments, we carried out a procedure for the development of hypoxia preconditioning in adult male Wistar rats using hypoxic exposure (9% O(2); 91% N(2)) for 1 h. The protection against p...

journal_title：Brain research

authors： Rauca C,Zerbe R,Jantze H,Krug M

更新日期：2000-06-16 00:00:00

abstract：:Intracranial microdialysis was used to measure dopamine (DA) release in the ventrolateral neostriatum of freely moving rats before and after unilateral tactile stimulation was applied to the orofacial region. Several behavioral parameters which have been linked to changes in nigrostriatal DA transmission (scanning, or...

journal_title：Brain research

authors： Adams F,Schwarting RK,Boix F,Huston JP

更新日期：1991-07-12 00:00:00

abstract：:The laminin-alpha2 chain is a component of brain capillary basement membranes and appears also to be present in neurons of rat, rabbit, pig and non-human primate brain as evidenced by immunohistochemistry. In the present study, we have further characterized this very distinct neuronal laminin-alpha2 chain-like immunor...

journal_title：Brain research

authors： Tian M,Hagg T,Denisova N,Knusel B,Engvall E,Jucker M

更新日期：1997-08-01 00:00:00

abstract：:Opioid modulation of calcium currents was studied in acutely dissociated rat basal forebrain neurons using the whole cell patch-clamp recording technique. The mu-opioid receptor agonist DAGO reversibly suppressed high-voltage activated calcium currents and slowed their rate of activation, while neither delta- nor kapp...

journal_title：Brain research

authors： Soldo BL,Moises HC

更新日期：1997-05-30 00:00:00

abstract：:The central axon of a primary afferent neuron that responded to light mechanical stimulation of the lower premolar teeth in a fast adapting fashion was intra-axonally injected with horseradish peroxidase in the cat. The labeled terminals within the rostrodorsomedial (Vo.r) and dorsomedial (Vo.dm) parts of subnucleus o...

journal_title：Brain research

authors： Bae YC,Nagase Y,Yoshida A,Shigenaga Y,Sugimoto T

更新日期：1993-03-19 00:00:00

abstract：:In a focused attention task saccadic reaction time (SRT) to a visual target stimulus (LED) was measured with an auditory (white noise burst) or tactile (vibration applied to palm) nontarget presented in ipsi- or contralateral position to the target. Crossmodal facilitation of SRT was observed under all configurations ...

journal_title：Brain research

authors： Diederich A,Colonius H

更新日期：2008-11-25 00:00:00

abstract：:The ventral tegmental area (VTA) is a brain region centrally involved in the development and expression of a variety of behaviors associated with drug use. Orexin/hypocretin (ox/hcrt) and corticotropin releasing factor (CRF) are both peptides released into the VTA, and an increasing number of studies show that both ox...

journal_title：Brain research

authors： Borgland SL,Ungless MA,Bonci A

更新日期：2010-02-16 00:00:00

abstract：:The alpha-2 adrenergic agonist dexmedetomidine (Dex), 3-300 microg/kg, i.p., decreased cerebellar cGMP in a dose-dependent manner. Fentanyl (F), an opioid agonist, increased cerebellar cGMP at 0.3 mg/kg, s.c., and decreased it at doses >/=1 mg/kg. The inhibitory effect was receptor specific, that of Dex being blocked ...

journal_title：Brain research

authors： Vulliemoz Y,Virag L,Whittington RA

更新日期：1998-11-30 00:00:00

abstract：:We identified the burst and single-spiking cells, and the repetitive bursting cells in layers III and V of the cat sensorimotor cortex with intracellular recording and staining techniques. Both types of the bursting cells were found in 22.7% of the recorded layer V neurons and in 23.1% of the recorded neurons in layer...

journal_title：Brain research

authors： Nishimura Y,Kitagawa H,Saitoh K,Asahi M,Itoh K,Yoshioka K,Asahara T,Tanaka T,Yamamoto T

更新日期：1996-07-15 00:00:00

abstract：:The weakly electric fish Apteronotus leptorhynchus produces electric organ discharges which are highly stable in waveform and frequency. Short-term modulations of these discharges, typically displayed during social interactions, are controlled by the prepacemaker nucleus (PPn). Neurons of this thalamic cell group inte...

journal_title：Brain research

authors： Zupanc GK,Horschke I

更新日期：1996-11-11 00:00:00

abstract：:Perfusion of the forebrain with glucose at concentrations which alter neither plasma insulin nor glucose levels leads to sympathetic activation in some rats. We used the expression of Fos-like immunoreactivity (FLI) as an index of neuronal activation to examine the anatomic substrate underlying this phenomenon. Male S...

journal_title：Brain research

authors： Dunn-Meynell AA,Govek E,Levin BE

更新日期：1997-02-14 00:00:00

abstract：:Choline is an essential nutrient whose availability during the second half of gestation produces long-lasting cognitive effects. Rats that obtain supplemental choline during embryonic day (E) 11-17 have enhanced depolarization-evoked acetylcholine (ACh) release from hippocampal slices, whereas choline deficiency durin...

journal_title：Brain research

authors： Napoli I,Blusztajn JK,Mellott TJ

更新日期：2008-10-27 00:00:00

abstract：:Kallikrein hydrolyzes various biologically active peptides, other than kininogens, such as vasoactive intestinal polypeptide (VIP), in vitro. Since kallikrein and VIP have been immunohistochemically shown to be present in the perivascular areas of the pineal gland, this study was designed to determine their topographi...

journal_title：Brain research

authors： Kudo M,Yamazaki I,Suzuki T,Ebihara Y,Iwadate H,Kizuki K

更新日期：1998-06-29 00:00:00

abstract：:Intracisternal (i.c.) administration of the glutamate-receptor antagonist kynurenate to halothane-anesthetized rats (paralyzed, ventilated) produced an initial hypertension associated with an increase in lumbar sympathetic nerve discharge. Kynurenate (i.c.) blocked or greatly reduced all sympathetic reflexes investiga...

journal_title：Brain research

authors： Sun MK,Hackett JT,Guyenet PG

更新日期：1988-01-12 00:00:00

abstract：:Basal limbic structures (insula, amygdala, hippocampus and surrounding areas) were explored for unit responses to vagal volleys in awake, sitting, squirrel monkeys. Triple shocks were applied every 4 sec to the left cervical vagus nerve. As a control for adventitious activation by extravagal somatic afferents, units r...

journal_title：Brain research

authors： Radna RJ,MacLean PD

更新日期：1981-05-25 00:00:00

abstract：:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces dopaminergic neuron death in substantia nigra and dopamine loss in striatum, similar to those observed in Parkinson disease. Given MPTP can also induce alterations in brain cytokines and in peripheral immune parameters, we hypothesize that MPTP can induce an ...

journal_title：Brain research

authors： Shen YQ,Hebert G,Su Y,Moze E,Neveu PJ,Li KS

更新日期：2005-05-31 00:00:00

abstract：:The time course and the relation to dose of regional cerebral metabolic rates for glucose (rCMRglc) were measured in awake male adult Fischer-344 rats after administration of quipazine, a serotonin 5-HT2-3 receptor agonist. rCMRglc was determined, using the quantitative autoradiographic [14C]deoxyglucose technique, in...

journal_title：Brain research

authors： Freo U,Ricchieri GL,Holloway HW,Soncrant TT

更新日期：1993-01-15 00:00:00

abstract：:The nitric oxide (NO) metabolome and the NO metabolite-based neurovascular protective pathways are dysregulated after stroke. The major NO metabolite S-nitrosoglutahione (GSNO) is essential for S-nitrosylation-based signaling events and the inhibition of S-nitrosoglutahione (GSNO)-metabolizing enzyme GSNO reductase (G...

journal_title：Brain research

authors： Khan M,Kumar P,Qiao F,Islam SMT,Singh AK,Won JS,Feng W,Singh I

更新日期：2020-08-15 00:00:00

abstract：:Strychnine-sensitive glycine receptors (GlyR) play a major role in the excitability of CNS neurons and are also a major target of many drugs including some general anesthetics and ethanol. The prefrontal cortex (PFC) is an important substrate responsible for cognitive function and for sedation, as well as hypnosis (un...

journal_title：Brain research

authors： Lu Y,Ye JH

更新日期：2011-06-01 00:00:00

abstract：:Ultrastructural localization of a calcium-binding protein, calretinin, in the cerebellar cortex of the rat was examined with an immunoperoxidase method. The cerebellar lobule V was investigated in detail. In the molecular layer, calretinin immunoreactivity was found in parallel fibers and in their varicosities that fo...

journal_title：Brain research

authors： Arai R,Jacobowitz DM,Deura S

更新日期：1993-06-11 00:00:00

abstract：:Putative N-type voltage-sensitive calcium channels were localized autoradiographically in thaw-mounted rat brain slices using [125I]omega-conotoxin GVIA as a ligand. Density of the toxin binding sites were highly heterogeneous throughout the brain. The highest density of the binding sites was observed in the glomerula...

journal_title：Brain research

authors： Takemura M,Kiyama H,Fukui H,Tohyama M,Wada H

更新日期：1988-06-07 00:00:00

abstract：:The localization of a GTP-binding protein (G(o)) in the cerebellar and cerebral cortex and hippocampus of the normal and reeler mutant mouse was immunohistochemically examined using affinity-purified antibody raised against the alpha subunit of G(o). Although the general distribution pattern of G(o)-immunoreactive pro...

journal_title：Brain research

authors： Terashima T,Katada T,Ichikawa R,Ui M,Inoue Y

更新日期：1993-01-22 00:00:00

abstract：:In previous studies we found that in the extremely polydipsic special strain of mice, STR/N, spontaneous drinking was greatly attenuated by injection of the opioid antagonists given intracerebroventricularly as well as subcutaneously. Therefore, we investigated, using hypothalamic slice preparations, responses of neur...

journal_title：Brain research

authors： Hattori Y,Katafuchi T,Koizumi K

更新日期：1991-01-11 00:00:00

abstract：:The neural connections from the ventral pallidum (VP) through the mediodorsal nucleus of the thalamus (MD) to the medial prefrontal cortex (MPC) were investigated. Extracellular recordings were made from 219 neurons in the medial and lateral portions of the MD and the VP and the MPC were stimulated. The most frequent ...

journal_title：Brain research

authors： Vives F,Mogenson GJ

更新日期：1985-10-07 00:00:00

abstract：:Dorsal cells, are primary sensory neurons located in the lamprey spinal cord. They are of two types conveying touch (T) and pressure (P) and they have an ascending and/or a descending axon which joins the dorsal column. Dorsal cells have no initial axon segment. In the electron microscope synaptic boutons with spheric...

journal_title：Brain research

authors： Christenson J,Lagerbäck PA,Grillner S

更新日期：1988-02-02 00:00:00

abstract：:4-hydroxybenzyl alcohol (4-HBA), one of the major active phenolic constituents of Gastrodia elata Blume, a very important traditional Chinese medicinal herb, has been shown to be an effective agent against the central and peripheral nervous disorders. In this study, we attempted to explore the possible mechanisms unde...

journal_title：Brain research

authors： Yu SS,Zhao J,Zheng WP,Zhao Y

更新日期：2010-01-13 00:00:00

abstract：:Partial sciatic nerve ligation in mice caused a marked and persistent decrease in the latency of paw withdrawal from a thermal stimulus only on the ipsilateral side. This thermal hyperalgesia was abolished by repeated intrathecal pretreatment with a specific antibody to brain-derived neurotrophic factor (BDNF), but no...

journal_title：Brain research

authors： Yajima Y,Narita M,Narita M,Matsumoto N,Suzuki T

更新日期：2002-12-27 00:00:00

abstract：:Two experiments were undertaken to investigate dopaminergic involvement in the local rate of responding on a fixed ratio 5 (FR5) instrumental lever pressing schedule. Rats were trained to press a lever for food reinforcement on a FR5 schedule, and a computer program was used to record the interresponse time (IRT) for ...

journal_title：Brain research

authors： Salamone JD,Kurth PA,McCullough LD,Sokolowski JD,Cousins MS

更新日期：1993-11-19 00:00:00

abstract：:The firing rate of the neurons of the hypothalamic paraventricular nucleus, the temperatures of the interscapular brown adipose tissue and of the colon (TIBAT and Tc) were monitored in 24 urethane-anesthetized male Sprague-Dawley rats divided into four groups. These variables were measured before and after hippocampal...

journal_title：Brain research

authors： Monda M,Viggiano A,Sullo A,De Luca V

更新日期：1999-04-03 00:00:00

abstract：:The aim of the present study was to investigate the effects of ischemic preconditioning on infarct volume in a rat model of subdural hematoma (SDH). Ischemic preconditioning was induced by 15 min transient middle cerebral artery (MCA) occlusion followed 3 days later by the injection of 300 microl of autologous venous ...

journal_title：Brain research

authors： Mackay KB,Stiefel TH,Foster AC

更新日期：2002-03-15 00:00:00