Time- and dose-dependent effects of the serotonergic agent quipazine on regional cerebral metabolism in rats.

abstract：:Coupling between lumbar motoneurons in the isolated frog spinal cord was studied by using intracellular recordings and intracellular injections of Lucifer Yellow CH. Physiological studies revealed intra- and intersegmental, short latency electrical interactions between many motoneurons. Injections of Lucifer Yellow in...

journal_title：Brain research

authors： Brenowitz GL,Collins WF 3rd,Erulkar SD

更新日期：1983-09-12 00:00:00

abstract：:Sequential effects--reduced behavioral interference after incongruent trials-provide a unique opportunity to examine the influence of previous experience on current attentional processing. We conducted a theoretical analysis of performance in the Simon paradigm to distinguish an attention account (conflict adaptation)...

journal_title：Brain research

authors： Chen S,Melara RD

更新日期：2009-11-10 00:00:00

abstract：:We recorded from the visual cortex of 4 groups of monocularly deprived kittens. Three groups were treated with intraventricular 6-hydroxydopamine (6-OHDA) at different times relative to monocular deprivation (MD). One group received only vehicle solution and MD. 6-OHDA caused the greatest decrease in plasticity in the...

journal_title：Brain research

authors： Allen EE,Blakemore LJ,Trombley PQ,Gordon B

更新日期：1987-03-01 00:00:00

abstract：:We cloned the genes for the mouse homologue of the neuromedin B receptor (NMB-R) and the bombesin receptor subtype 3 (BRS-3). Both receptor genes consist of three exons with well-conserved intron-exon borders. Although the NMB-R gene spans more than 10 kb, the BRS-3 gene spans only about 4 kb. Comparison of the mouse ...

journal_title：Brain research

authors： Ohki-Hamazaki H,Wada E,Matsui K,Wada K

更新日期：1997-07-11 00:00:00

abstract：:Colchicine was injected into the region of the organum vasculosum lamina terminalis/anterior region of the third cerebral ventricle (OVLT/AV3V) to produce a temporary disruption of the nervous connections of this area and the rest of the anterior hypothalamus, but to maintain the vascular connections intact. Rats were...

journal_title：Brain research

authors： Thornton SN,Sirinathsinghji DJ,Delaney CE

更新日期：1987-12-29 00:00:00

abstract：:The neuroprotective effects of N-stearoyl-L-tyrosine (NSTyr) on cognitive function and neuronal plasticity during chronic cerebral hypoperfusion (CCH) in rats were investigated. After induction of CCH, NSTyr was administered daily for 3 months intraperitoneally. Cognitive functions were evaluated by Morris water maze ...

journal_title：Brain research

authors： Lin Q,Hai J,Yao LY,Lu Y

更新日期：2010-04-14 00:00:00

abstract：:Accumulating evidence suggests that the neuropeptide substance P (SP) and its principal receptor neurokinin 1 (NK1) play a specific role in the behavioral response to opioids and stress that may help to initiate and maintain addictive behavior. In animal models, the NK1 receptor is required for opioids to produce thei...

journal_title：Brain research

authors： Commons KG

更新日期：2010-02-16 00:00:00

abstract：:The visual properties of cells in the cat ventral lateral geniculate nucleus (LGV) identified antidromically from the pretectum and/or superior colliculus (projection cells) were studied in comparison with those of LGV neurons which could not be activated antidromically (non-projection cells). ON-phasic receptive fiel...

journal_title：Brain research

authors： Hada J,Yamagata Y,Hayashi Y

更新日期：1986-01-15 00:00:00

abstract：:Glial cells play a crucial role in the pathomechanism of perinatal hypoxic-ischemic brain injury (HI) and are involved in the maintenance of a chronic state of inflammation that causes delayed neuronal damage. Activation of astrocytes is one factor prolonging brain damage and contributing to the formation of a glial s...

journal_title：Brain research

authors： Wasielewski B,Jensen A,Roth-Härer A,Dermietzel R,Meier C

更新日期：2012-12-03 00:00:00

abstract：:We examined the in vivo synthesis of brain phosphatidylcholine (PC) by the methylation of phosphatidylethanolamine (PE). [3H-methyl]methionine was infused i.c.v., by indwelling cannula, and brain samples were taken 0.5-18 h thereafter and assayed for [3H]PC, as well as for its biosynthetic intermediates [3H]phosphatid...

journal_title：Brain research

authors： Lakher M,Wurtman RJ

更新日期：1987-09-01 00:00:00

abstract：:alpha-Motoneurons innervating the triceps surae and short plantar muscles were stained intracellularly with horseradish peroxidase (HRP) in 0-44-day-old kittens and adult cats. The terminal arborizations of the recurrent axon collaterals in the spinal cord were studied in the light microscope (LM). The short plantar m...

journal_title：Brain research

authors： Cullheim S,Ulfhak B

更新日期：1985-01-01 00:00:00

abstract：:Using [3H]para-aminoclonidine, alpha 2 adrenergic binding sites have been mapped in the rat and human CNS using in vitro labeling autoradiographic techniques. In both the rat and human thoracic spinal cord, high densities of alpha 2 binding sites were associated with the substantia gelatinosa and the intermediolateral...

journal_title：Brain research

authors： Unnerstall JR,Kopajtic TA,Kuhar MJ

更新日期：1984-03-01 00:00:00

abstract：:Picture-word interference is a widely employed paradigm to investigate lexical access in word production: Speakers name pictures while trying to ignore superimposed distractor words. The distractor can be congruent to the picture (pictured cat, word cat), categorically related (pictured cat, word dog), or unrelated (p...

journal_title：Brain research

authors： Piai V,Roelofs A,van der Meij R

更新日期：2012-04-23 00:00:00

abstract：:The melanocortins (MC) can affect interscapular brown adipose tissue (IBAT) thermogenesis via its sympathetic nervous system (SNS) innervation. We chose a site of high MC4-receptor (MC4-R) mRNA co-localization with SNS outflow neurons to IBAT, the subzona incerta (subZI) to test whether IBAT thermogenesis could be inc...

journal_title：Brain research

authors： Vaughan CH,Shrestha YB,Bartness TJ

更新日期：2011-09-09 00:00:00

abstract：:A selective 5-HT reuptake inhibitor, fluvoxamine (10 and 30 mg/kg, i.p.) suppressed long-term potentiation (LTP) in the hippocampal CA1 field of anesthetized rats. Fluvoxamine (30 mg/kg, i.p.)-induced suppression of LTP was completely reversed by the 5-HT(1A) receptor antagonist NAN-190 (0.5 mg/kg, i.p), but not by th...

journal_title：Brain research

authors： Kojima T,Matsumoto M,Togashi H,Tachibana K,Kemmotsu O,Yoshioka M

更新日期：2003-01-03 00:00:00

abstract：:Antisense oligodeoxynucleotide (AS ODN) probes directed against the alpha-subunit of different G-proteins have been used to differentiate feeding responses in rats elicited by different opioid agonists, including morphine, beta-endorphin and dynorphin. Furthermore, antisense probes directed against G(o)alpha, but not ...

journal_title：Brain research

authors： Hadjimarkou MM,Silva RM,Rossi GC,Pasternak GW,Bodnar RJ

更新日期：2002-11-15 00:00:00

abstract：:Our recent researches have identified increased expression of miR-21-5p in rats brain following traumatic brain injury (TBI), which protected against blood-brain barrier (BBB) damage. To further study the mechanism underlying the role of miR-21-5p on alleviating BBB damage after TBI, we performed the scratch injury mo...

journal_title：Brain research

authors： Ge X,Huang S,Gao H,Han Z,Chen F,Zhang S,Wang Z,Kang C,Jiang R,Yue S,Lei P,Zhang J

更新日期：2016-11-01 00:00:00

abstract：:Neuronal expression of c-fos product in the cat rostral ventrolateral medulla was studied by immunohistochemistry. Spinally projecting neurons of the subretrofacial (SRF) nucleus were pre-labeled by retrograde transport of fluorescent latex microspheres from the lumbar cord. In 3 animals which were bled by approximate...

journal_title：Brain research

authors： McAllen RM,Badoer E,Shafton AD,Oldfield BJ,McKinley MJ

更新日期：1992-03-20 00:00:00

abstract：:Bilateral microinjection of kainic acid (30-117 pmol) into the substantia nigra induced convulsive seizures resembling those elicited from limbic system structures. The convulsive seizures, which consisted of facial and forelimb clonus with rearing and falling, developed after a latency of more than 30 min and were pr...

journal_title：Brain research

authors： Maggio R,Liminga U,Gale K

更新日期：1990-10-01 00:00:00

abstract：:L-Tryptophan produces a significant antihypertensive effect in spontaneously hypertensive rats while D-tryptophan does not change blood pressure. Both isomers of tryptophan significantly increase brain serotonin to the same extent at a time when the antihypertensive effect of L-tryptophan is maximal. Thus, the antihyp...

journal_title：Brain research

authors： Wolf WA,Kuhn DM

更新日期：1984-03-19 00:00:00

abstract：:The neurosteroid allopregnanolone is a potent and efficacious modulator of gamma-aminobutyric acid (GABA) type A receptors. The effects of intracerebroventricular injection of allopregnanolone (5 to 15 micrograms/5 microliters) on basal and stress-induced release of acetylcholine were investigated in various regions o...

journal_title：Brain research

authors： Dazzi L,Sanna A,Cagetti E,Concas A,Biggio G

更新日期：1996-02-26 00:00:00

abstract：:The innervation of the tensor tympani muscle of the middle ear in Macaca fascicularis (cynomolgus monkey) was studied using the horseradish peroxidase (HRP) neural tracing technique. A compact column of small trigeminal motoneurons was labeled ipsilaterally following intramuscular application of HRP to the tensor tymp...

journal_title：Brain research

authors： Gannon PJ,Eden AR

更新日期：1987-02-24 00:00:00

abstract：:Whole-cell voltage-clamp techniques were used to study the comparative effects of delta-9-tetrahydrocannabinol (THC) and its principal metabolite, 11-hydroxy-delta-9-tetrahydrocannabinol (11-OH-THC), on the voltage-gated sodium current in neuroblastoma cells. The parent compound markedly depressed the inward sodium cu...

journal_title：Brain research

authors： Turkanis SA,Karler R,Partlow LM

更新日期：1991-09-27 00:00:00

abstract：:Attempts were made to determine the cells of origin of the spinal projections to the PAG using retrograde axoplasmic transport techniques of HRP and fluorescent markers. Following injections limited to the lateroventral subnucleus of the PAG, labels were transported to the contralateral laminae I, III, V, VII and X pr...

journal_title：Brain research

authors： Liu RP

更新日期：1983-03-28 00:00:00

abstract：:Depolarizing actions of 4 conformationally restricted L-glutamate analogues, (2S,3S,4S) isomer (L-CCG-I), (2S,3R,4R) isomer (L-CCG-II), (2S,3S,4R) isomer (L-CCG-III) and (2S,3R,4S) isomer (L-CCG-IV) of L-alpha-(carboxycyclopropyl)-glycine (L-CCG), were investigated in the isolated rat spinal cord by extracellular reco...

journal_title：Brain research

authors： Shinozaki H,Ishida M,Shimamoto K,Ohfune Y

更新日期：1989-02-20 00:00:00

abstract：:A total of 183 nucleus basalis of Meynert (NBM) neurons were recorded in a monkey performing a delayed response task. Significant changes in discharge rate were detected in 74% of the NBM cells sampled with most responses occurring in the choice (64%) or the reward (67%) epochs of the task. Neuronal responses in the c...

journal_title：Brain research

authors： Richardson RT,DeLong MR

更新日期：1986-12-10 00:00:00

abstract：:The subfornical organ (SFO), a neuroendocrine structure implicated in saltwater homeostasis, contains secretory structures histochemically similar to those in the neurohypophysis. Because of these morphological similarities, we compared levels of vasopressin (vp) in the SFO area and the adjacent hippocampal commissure...

journal_title：Brain research

authors： Summy-Long JY,Keil LC,Severs WB

更新日期：1978-01-27 00:00:00

abstract：:The activity of cerebellar Purkinje cells during controlled and passive movement of the forepaw was studied in the cat. Burst responses characteristic of activation by climbing fibers were observed in Purkinje cells in lobules Vb and Vc of the cerebellar vermis and paravermis. The climbing fiber responses followed the...

journal_title：Brain research

authors： Rushmer DS,Roberts WJ,Augter GK

更新日期：1976-04-16 00:00:00

abstract：:While schizophrenia has a genetic component, its pathogenesis is unknown. Abnormal concentrations of two cell recognition molecules (CRMs), neural-cell adhesion molecule (N-CAM) and L1 antigen have been described in the cerebrospinal fluid (CSF) of patients with schizophrenia. Studies of monozygotic twins discordant f...

journal_title：Brain research

authors： Poltorak M,Wright R,Hemperly JJ,Torrey EF,Issa F,Wyatt RJ,Freed WJ

更新日期：1997-03-14 00:00:00

abstract：:Release of Ca(2+) from intracellular Ca(2+) stores (ICS) is involved in age-related changes in the induction of long-term potentiation. However, the role of this Ca(2+) source for the increased susceptibility to long-term depression (LTD) with advanced age is unknown. Extracellular excitatory postsynaptic field potent...

journal_title：Brain research

authors： Kumar A,Foster TC

更新日期：2005-01-07 00:00:00