Hemorrhage induces c-fos immunoreactivity in spinally projecting neurons of cat subretrofacial nucleus.

Abstract:

:Neuronal expression of c-fos product in the cat rostral ventrolateral medulla was studied by immunohistochemistry. Spinally projecting neurons of the subretrofacial (SRF) nucleus were pre-labeled by retrograde transport of fluorescent latex microspheres from the lumbar cord. In 3 animals which were bled by approximately 25% blood volume from a carotid cannula, 48-62% of SRF-spinal neurons expressed c-fos immunoreactivity. In 2 control animals, the corresponding values were 2% and 4%. The data show that bulbospinal neurons of presumed vasomotor function express c-fos in response to hemorrhage.

journal_name

Brain Res

journal_title

Brain research

authors

McAllen RM,Badoer E,Shafton AD,Oldfield BJ,McKinley MJ

doi

10.1016/0006-8993(92)90099-u

subject

Has Abstract

pub_date

1992-03-20 00:00:00

pages

329-32

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(92)90099-U

journal_volume

575

pub_type

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