Intrathecal galanin blocks the prolonged increase in spinal cord flexor reflex excitability induced by conditioning stimulation of unmyelinated muscle afferents in the rat.

abstract：:We have previously identified a cell senescence-related, detergent-insoluble cytoplasmic protein referred to as terminin, and have presented the development-dependent modification of terminin polypeptides in rat brain. In the present study, we characterize biochemically and immunocytochemically terminin expression in ...

journal_title：Brain research

authors： Yang G,Wang E

更新日期：1994-05-02 00:00:00

abstract：:Autoradiographic analysis of [(35)S]GTPgammaS binding was used to investigate functional activation of dopamine receptors in rat striatum. Dopamine-stimulated [(35)S]GTPgammaS binding was observed with a maximal increase of 38% over basal activity. A similar stimulatory response was obtained with the D(2) agonist quin...

journal_title：Brain research

authors： He L,Di Monte DA,Langston JW,Quik M

更新日期：2000-12-01 00:00:00

abstract：:Neurotrophic factors (NTFs), beside regulating neuronal survival in the central and peripheral nervous system, are also involved in the modulation of neuronal function in the adult animal. Both brain-derived neurotrophic factor (BDNF) and glial cell-derived neurotrophic factor (GDNF) levels are altered in pathological...

journal_title：Brain research

authors： Ciobanu C,Reid G,Babes A

更新日期：2009-08-11 00:00:00

abstract：:The possible involvement of protein kinase A (PKA) in the muscarinic inhibition of the slow afterhyperpolarizing current (IAHP) was investigated in rat hippocampal pyramidal cells. IAHP was recorded using the whole cell method in hippocampal slices, and Rp-cAMPS, a PKA antagonist, was applied intracellularly. The inhi...

journal_title：Brain research

authors： Blitzer RD,Wong T,Nouranifar R,Landau EM

更新日期：1994-05-23 00:00:00

abstract：:To evaluate roles of the sympathetic nervous system in enhancing glucose uptake in skeletal muscles in response to electrical stimulation of the ventromedial hypothalamic nucleus (VMH), the effects of guanethidine treatment and adrenal demedullation on the response were examined in rats anesthetized and injected with ...

journal_title：Brain research

authors： Minokoshi Y,Okano Y,Shimazu T

更新日期：1994-06-27 00:00:00

abstract：:Thermoregulation is a complex intercommunicative function requiring coordination between core body temperature (CBT), the central nervous system, and peripheral vasculature. In menopausal women, dysregulation of thermoregulatory mechanisms leads to hot flushes and night sweats. A previous study in ovariectomized (OVX)...

journal_title：Brain research

authors： Pawlyk AC,Cosmi S,Alfinito PD,Maswood N,Deecher DC

更新日期：2006-12-06 00:00:00

abstract：:Responses of pyramidal neurons to ionophoretic kainate, quisqualate and N-methyl aspartate were studied in a submerged rat piriform cortex slice as a function of Ca2+ and Mg2+ concentrations. The results suggest that the channel activated by kainate is unusually influenced by Ca2+, excitotoxicity is Ca2+-dependent and...

journal_title：Brain research

authors： Hori N,Ffrench-Mullen JM,Carpenter DO

更新日期：1985-12-09 00:00:00

abstract：:Extracellular recordings were made from a type of relay neurons of the superior laryngeal nerve (SLN) afferents in the vicinity of the retrofacial nucleus (RFN) in either pentobarbitone-anesthetized or unanesthetized and decerebrate cats, which were paralyzed and artificially ventilated. A total of 26 neurons that cou...

journal_title：Brain research

authors： Ezure K,Oku Y,Tanaka I

更新日期：1993-12-31 00:00:00

abstract：:We characterized acute intracerebral hemorrhage (ICH) in the rat by sequential magnetic resonance imaging (MRI) and correlated MRI findings with neurobehavior and histopathology. In addition, we investigated whether albumin treatment would reduce ICH-induced brain injury. ICH was produced in rats by a double-injection...

journal_title：Brain research

authors： Belayev L,Obenaus A,Zhao W,Saul I,Busto R,Wu C,Vigdorchik A,Lin B,Ginsberg MD

更新日期：2007-07-09 00:00:00

abstract：:The effect of aging on delta opioid receptors was examined in the brains of guinea pigs aged 1, 6, 24 and 36 months. Quantitative autoradiography was used to monitor the concentrations of delta receptors in various anatomical regions at five rostro-caudal levels. delta opioid receptor populations were found to be rema...

journal_title：Brain research

authors： Hiller JM,Fan LQ,Simon EJ

更新日期：1993-06-18 00:00:00

abstract：:The properties of [3H]dihydropyridine (DHP), nitrendipine and (+)-PN 200-110, binding to rat cerebral membranes were investigated. In normotensive Wistar-Kyoto (WKY) adult rats, the highest densities of [3H]DHP binding sites were found in the hippocampus. Frontal cerebral cortex and hypothalamus had intermediate level...

journal_title：Brain research

authors： Huguet F,Huchet AM,Gerard P,Narcisse G

更新日期：1987-05-26 00:00:00

abstract：:Using in vivo microdialysis, we examined the ability of choline (Ch) chloride (120 mg/kg i.p.) to amplify basal and stimulated acetylcholine (ACh) release from rat striatum in the presence of high (10(-5) M) and low (5 x 10(-8) M) neostigmine concentration. High concentrations might suppress ACh release, and thus Ch d...

journal_title：Brain research

authors： Marshall DL,Wurtman RJ

更新日期：1993-12-03 00:00:00

abstract：:Placental Opioid-Enhancing Factor (POEF) is a substance found in amniotic fluid (AF) that, when ingested, potentiates opioid-mediated, but not non-opioid-mediated, hypoalgesia. Vaginal-cervical stimulation (VCS) produces a stimulus-bound, partially opioid-mediated hypoalgesia that previous research has shown to be pot...

journal_title：Brain research

authors： Hoey RF,Hurley SW,Daniels D,Kristal MB

更新日期：2011-02-28 00:00:00

abstract：:We have used the post-embedding immunogold labelling method using antibodies to gamma-aminobutyric acid (GABA) to obtain quantitative data on the distribution, frequency, postsynaptic targets and ultrastructural characteristics of GABA-immunoreactive (GABA-IR) boutons in the trigeminal motor nucleus of rats. We have a...

journal_title：Brain research

authors： Saha S,Appenteng K,Batten TF

更新日期：1991-10-04 00:00:00

abstract：:The regional hemodynamic basis of the cardiovascular response to acute noise stress in spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats and the role of the central amygdaloid nucleus in mediating this response was investigated. Using the pulsed Doppler flow probe technique it was determined that in respons...

journal_title：Brain research

authors： Galeno TM,Van Hoesen GW,Brody MJ

更新日期：1984-01-23 00:00:00

abstract：:Intracellular assessments of the physiological actions of cannabinoid receptor agonists and antagonists on adult hippocampal CA1 pyramidal cells in the in vitro slice preparation were performed using current clamp and conventional sharp-electrode intracellular recording procedures. Several manipulations were performed...

journal_title：Brain research

authors： Kirby MT,Hampson RE,Deadwyler SA

更新日期：2000-04-28 00:00:00

abstract：:Single unit extracellular recordings were obtained from cat lumbar spinal cord dorsal horn neurons activated by cutaneous inputs. The effect of electrical conditioning stimuli applied to the red nucleus (RN) was predominantly that of inhibition although in some cases excitation was seen. All the neurons that projected...

journal_title：Brain research

authors： Gray BG,Dostrovsky JO

更新日期：1984-10-08 00:00:00

abstract：:Recently, this laboratory provided evidence that interleukin-1beta (IL-1beta), an immune and brain-derived cytokine, microinjected into the medial hypothalamus, potentiates defensive rage behavior in the cat elicited from the midbrain periaqueductal gray (PAG), and that such effects are blocked by a 5-HT2 receptor ant...

journal_title：Brain research

authors： Hassanain M,Bhatt S,Zalcman S,Siegel A

更新日期：2005-06-28 00:00:00

abstract：:Cigarette smoke passed through the nasal cavity of atenolol pre-treated anesthetized spontaneously breathing rabbits caused a bradycardia which was significantly modified by intracisternal application of the 5-HT1A receptor ligands 8-OH-DPAT (50 micrograms.kg-1) and buspirone (200 micrograms.kg-1). 8-OH-DPAT attenuate...

journal_title：Brain research

authors： Futuro-Neto HA,Pires JG,Gilbey MP,Ramage AG

更新日期：1993-12-03 00:00:00

abstract：:Locations of cells responsive to microiontophoretically applied angiotensin II (AII) were compared to distributions of AII receptor binding sites identified by autoradiography in the lumbar enlargement region of the rat spinal cord. Angiotensin II receptor binding sites were densely concentrated in the superficial lay...

journal_title：Brain research

authors： White SR,Penner JD,Speth RC,Chan JY

更新日期：1988-02-16 00:00:00

abstract：:Although transsynaptic tracing with peripheral injection of pseudorabies virus (PRV) has been extensively characterized, several methodological issues related to central application of this tracer have not been addressed. In the present study, we addressed the following three issues by using microinjection of a cockta...

journal_title：Brain research

authors： Chen S,Yang M,Miselis RR,Aston-Jones G

更新日期：1999-08-14 00:00:00

abstract：:To determine the effects of nerve injury on Fos expression, temporal and spatial distributions of Fos-positive neurons in the trigeminal nucleus caudalis were examined after tissue injury for isolation of the infraorbital nerve as controls and transection of this nerve as well as noxious chemical stimulation by formal...

journal_title：Brain research

authors： Terayama R,Nagamatsu N,Ikeda T,Nakamura T,Rahman OI,Sakoda S,Shiba R,Nishimori T

更新日期：1997-09-12 00:00:00

abstract：:The startle reflex is an unconditioned, quantifiable behavior used to study sensory modalities. We examined whether the acoustic startle reflex (ASR) was sensitive to lesions induced by focal cerebral ischemia. Sprague-Dawley rats were pre-screened for startle reflex responses 3-6 days prior to surgery and there were ...

journal_title：Brain research

authors： Maynard KI,Sukoff SJ,Ji Z,Wettstein JG,Black MD

更新日期：2005-01-25 00:00:00

abstract：:Animal and cell experiments showed that inositol hexaphosphate (IP6) was protective on neurons in parkinson's disease (PD) model, but the underlying mechanism of this action was not extensively elucidated. To address this question, we established 6-hydroxydopamine (6-OHDA) induced human dopaminergic cell line SH-SY5Y ...

journal_title：Brain research

authors： Zhang Z,Hou L,Li X,Ju C,Zhang J,Li X,Wang X,Liu C,Lv Y,Wang Y

更新日期：2016-02-15 00:00:00

abstract：:An inhibitor of tissue plasminogen activator (tPA) was tested for its effects on the rapid kindling induced by a series of afterdischarges (ADs) triggered in hippocampus over a 3-h period. Rats injected with vehicle prior to the session had prolonged ADs in tests carried out 10 days later. This was not the case for an...

journal_title：Brain research

authors： Hoffman KB,Hwee V,Larson J,Lynch G

更新日期：2000-04-07 00:00:00

abstract：:Traumatic brain injury (TBI) causes impairments of both motor and spatial memory performances. Research is only beginning to reveal the biochemical mechanism(s) underlying these deficits. It has been postulated that reactive oxygen species such as the superoxide and hydroxyl radicals, as well as the peroxynitrite anio...

journal_title：Brain research

authors： Long DA,Ghosh K,Moore AN,Dixon CE,Dash PK

更新日期：1996-04-22 00:00:00

abstract：:Rats with bilateral striatal cholinergic lesions induced by the neurotoxin AF64A were found to have increased spontaneous nocturnal locomotor activity as measured in terms of the amount of time spent moving, the total distance traveled and the number of episodes and time of stereotypic behaviors. No significant differ...

journal_title：Brain research

authors： Sandberg K,Sanberg PR,Coyle JT

更新日期：1984-05-14 00:00:00

abstract：:Slices of rat hippocampus were exposed to 700 MHz continuous wave radiofrequency (RF) fields (25.2-71.0 V m(-1), 5-15 min exposure) in a stripline waveguide. At low field intensities, the predominant effect on the electrically evoked field potential in CA1 was a potentiation of the amplitude of the population spike by...

journal_title：Brain research

authors： Tattersall JE,Scott IR,Wood SJ,Nettell JJ,Bevir MK,Wang Z,Somasiri NP,Chen X

更新日期：2001-06-15 00:00:00

abstract：:Vagus nerve stimulation (VNS) has been used for years to treat patients with drug-resistant epilepsy. In the present study, the effect of different stimulation protocols of VNS on the hippocampal formation (HPC) type II theta field potentials were evaluated in anesthetized rats. The following theta parameters were ana...

journal_title：Brain research

authors： Broncel A,Bocian R,Kłos-Wojtczak P,Konopacki J

更新日期：2017-11-15 00:00:00

abstract：:The patch clamp technique has been used to study ion channel activity in the apical (ventricular) membrane of epithelial cells from the rat choroid plexus. Two different classes of Cl(-)-selective channel were identified. A low conductance (26 pS) channel which was the predominant feature in cell-attached and inside-o...

journal_title：Brain research

authors： Garner C,Brown PD

更新日期：1992-09-18 00:00:00