Abstract:
:Responses of pyramidal neurons to ionophoretic kainate, quisqualate and N-methyl aspartate were studied in a submerged rat piriform cortex slice as a function of Ca2+ and Mg2+ concentrations. The results suggest that the channel activated by kainate is unusually influenced by Ca2+, excitotoxicity is Ca2+-dependent and a function of Ca2+ concentration, and the excitotoxic actions of various amino acid agonists are correlated with the Ca2+ dependence of their responses.
journal_name
Brain Resjournal_title
Brain researchauthors
Hori N,Ffrench-Mullen JM,Carpenter DOdoi
10.1016/0006-8993(85)90989-8subject
Has Abstractpub_date
1985-12-09 00:00:00pages
380-4issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(85)90989-8journal_volume
358pub_type
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