Some transforming growth factor-alpha connections and their colocalization with enkephalin in the rat central nervous system.

abstract：:Slow negative potentials, evoked by stimulation of the lumbar dorsal roots, have been demonstrated in the dorsal horn of an isolated, hemisected spinal cord preparation from golden hamsters. Paired stimuli revealed a period of partial suppression of this slow potential persisting for up to 2 s following the conditioni...

journal_title：Brain research

authors： Bagust J,Forsythe ID,Kerkut GA,Loots JM

更新日期：1982-02-04 00:00:00

abstract：:To evaluate the role of the amygdala in pain modulation and opioid-mediated antinociception, a recombinant, replication-defective herpes virus carrying the human preproenkephalin cDNA was injected bilaterally into the rat amygdala. Four days after gene delivery nociceptive behavior was assessed by the formalin test. R...

journal_title：Brain research

authors： Kang W,Wilson MA,Bender MA,Glorioso JC,Wilson SP

更新日期：1998-05-04 00:00:00

abstract：:Repetitive stimulation of an axon in the right visceropleural connective to the abdominal ganglion of Aplysia californica produces post-tetanic potentiation (PTP) of a unitary monosynaptic EPSP recorded from cell R15. PTP decays within one half hour following cessation of repatitive stimulation. Stimulation of the lef...

journal_title：Brain research

authors： Newlin SA,Schlapfer WT,Barondes SH

更新日期：1980-01-06 00:00:00

abstract：:The origin of neuronal perikarya which project to the external zone of the median eminence (the tuberoinfundibular neuronal system) was determined in the rat after injection or diffusion of wheat germ agglutinin (WGA) into the median eminence. The retrogradely transported lectin was detected in neurons using an immuno...

journal_title：Brain research

authors： Lechan RM,Nestler JL,Jacobson S

更新日期：1982-08-05 00:00:00

abstract：:Retrograde transport of horseradish peroxidase (HRP) was used to identify supraependymal neurons projecting to the pituitary gland in the hamster. Supraependymal neurons overlying the median eminence were labeled by HRP injections into the neural and intermediate lobes of the pituitary gland; no neurons were labeled f...

journal_title：Brain research

authors： Michael DB,Hazlett JC,Mitchell JA

更新日期：1989-01-30 00:00:00

abstract：:A single electrode voltage clamp was used to examine the prolonged hyperpolarizing afterpotential (PHA) which accompanies photoconversion of a substantial fraction of rhodopsin (lambda max = 500 nM) to metarhodopsin (lambda max = 575 nM) in distal photoreceptor cells in the retina of the bay scallop, Pecten irradians....

journal_title：Brain research

authors： Cornwall MC,Gorman AL

更新日期：1982-05-13 00:00:00

abstract：:Regulation of tyrosine hydroxylase (TH) by second messenger pathway activators was examined in rat olfactory bulb cell cultures. The number of TH-immunoreactive neurons was increased 2-3-fold by 36 h treatments with forskolin (Fsk, 10(-6) M) or phorbol myristate acetate (PMA, 10(-7) M), but was not significantly incre...

journal_title：Brain research

authors： McMillian MK,Mullis SB,Wu GC,Hudson PM,Pennypacker KR,Hong JS

更新日期：1994-09-26 00:00:00

abstract：:Bilateral removal of the cortical visual area in newborn cats produces degeneration of retinal ganglion cells. Measurements of over 4,000 cells and calculation of neuron densities from sample areas of retina in the adult show that the medium sized cell population in peripheral retina is reduced by 68%, whereas the pop...

journal_title：Brain research

authors： Pearson HE,Labar DR,Payne BR,Cornwell P,Aggarwal N

更新日期：1981-05-18 00:00:00

abstract：:Changes in the astrocytic cytoskeleton were examined in amygdala kindled rats using immunocytochemical techniques. One week following kindling, there was a dramatic increase in immunoreactivity to glial fibrillary acidic protein and vimentin in astrocytes throughout amygdala, pyriform cortex and hippocampus bilaterall...

journal_title：Brain research

authors： Khurgel M,Racine RJ,Ivy GO

更新日期：1992-10-02 00:00:00

abstract：:The motivational effects of exclusively peripheral or central opiate receptor blockade were studied using place conditioning. Place aversions were observed with intraventricular (i.c.v.) methylnaloxone (MN) in both naive (200-1000 ng) and morphine-dependent rats (50-500 ng). Subcutaneous MN (0.03-10 mg/kg) was ineffec...

journal_title：Brain research

authors： Hand TH,Koob GF,Stinus L,Le Moal M

更新日期：1988-12-06 00:00:00

abstract：:Various chemical and physical lesions were employed to elucidate the cellular localization of cholecystokinin (CCK) receptors in the rat caudate nucleus. A wide knife cut severing all caudal afferents reduced caudate CCK receptors by approximately 25%, indicating that some receptors lie on axons and (or) terminals of ...

journal_title：Brain research

authors： Hays SE,Meyer DK,Paul SM

更新日期：1981-08-24 00:00:00

abstract：:Systemic administration of the protein synthesis inhibitor, cycloheximide, induced both phase advances and phase delays in the circadian rhythm of wheel-running activity in hamsters (Mesocricetus auratus) maintained in constant darkness or constant light. The magnitude and direction of the phase shifts were dependent ...

journal_title：Brain research

authors： Wollnik F,Turek FW,Majewski P,Takahashi JS

更新日期：1989-09-04 00:00:00

abstract：:Bilateral intranigral administration of the selective NK-1 tachykinin receptor agonist [AcArg6, Sar9, Met(O2)11]SP6-11 (0-1 nmol total bilateral dose) selectively induced grooming in rats. This response was blocked by concurrent intranigral administration of the NK-1 tachykinin receptor antagonist RP 67580 (2 nmol), b...

journal_title：Brain research

authors： Stoessl AJ,Brackstone M,Rajakumar N,Gibson CJ

更新日期：1995-11-27 00:00:00

abstract：:The distribution of agmatine (decarboxylated arginine) was mapped in the central nervous system (CNS) in the rat. Agmatine-like immunoreactivity was identified by light microscopy, exclusively in the cytoplasm of neuronal perikarya. Immunoreactive neurons were present in the cerebral cortex, predominantly within lamin...

journal_title：Brain research

authors： Otake K,Ruggiero DA,Regunathan S,Wang H,Milner TA,Reis DJ

更新日期：1998-03-16 00:00:00

abstract：:Transcription factors of the nuclear factor-kappa B (NF-kappaB) p65/RelA may be involved in neuronal cell death. We examined the involvement of NF-kappaB p65 in N-methyl-D-aspartate (NMDA)-induced upregulation of interleukin (IL)-1beta, a proinflammatory cytokine, and subsequent neurotoxicity in the rat retina. Immuno...

journal_title：Brain research

authors： Kitaoka Y,Munemasa Y,Nakazawa T,Ueno S

更新日期：2007-04-20 00:00:00

abstract：:We investigated whether the weak febrile response to pyrogens in newborns is due to a diminished activation of the putative pyrogen mediator, prostaglandin (PG)E2. Indwelling cannulas in the third ventricle of lambs (age, 5-31 days) and adult ewes were used to collect cerebrospinal fluid (CSF) for radioimmunoassay of ...

journal_title：Brain research

authors： Coceani F,Bishai I,Engelberts D,House RV,Adamson SL

更新日期：1995-11-27 00:00:00

abstract：:Long-term potentiation (LTP) has a memory-like consolidation period during which it becomes progressively stabilized. However, it is unknown how the consolidation is achieved. The present study demonstrates that nicotine reverses stabilized LTP in the hippocampal CA1 region, providing the first evidence that consolida...

journal_title：Brain research

authors： Guan X,Nakauchi S,Sumikawa K

更新日期：2006-03-17 00:00:00

abstract：:Instructions are an inextricable, yet poorly understood aspect of modern human life. In this paper we propose that instruction implementation and following can be understood as fast Hebbian learning in prefrontal cortex, which trains slower pathways (e.g., cortical-basal ganglia pathways). We present a computational m...

journal_title：Brain research

authors： Ramamoorthy A,Verguts T

更新日期：2012-02-23 00:00:00

abstract：:This study tested the hypothesis that the short-latency excitation of the phrenic motor output elicited by superior laryngeal nerve (SLN) stimulation requires non-NMDA receptor-mediated neurotransmission in the region of the dorsal respiratory group (DRG) of the adult cat. Injection of the non-NMDA receptor antagonist...

journal_title：Brain research

authors： Karius DR,Speck DF

更新日期：1995-06-05 00:00:00

abstract：:The effects of escapable and yoked inescapable electric tailshocks on extracellular levels of serotonin (5-HT) in the ventral hippocampus and dorsal periaqueductal gray (dPAG) were measured by in vivo microdialysis. Inescapable, but not escapable shock increased extracellular 5-HT in the ventral hippocampus relative t...

journal_title：Brain research

authors： Amat J,Matus-Amat P,Watkins LR,Maier SF

更新日期：1998-06-22 00:00:00

abstract：:This experiment was conducted to determine if nigrostriatal dopamine (DA) neurons are necessary for the contraversive rotational behavior evoked by electrical stimulation in the lateral hypothalamus. Rats were tested daily for electrical stimulation-induced rotational behavior (ESRB) for 5 days, and then given an inje...

journal_title：Brain research

authors： Castañeda E,Robinson TE,Becker JB

更新日期：1985-02-18 00:00:00

abstract：:We examined the effect of the molarless condition on the dendritic spines of hippocampal pyramidal cells in SAMP8 mice in comparison to its effect on learning ability in a maze test. The molarless condition caused a decrease in the number of the spines of CA1 pyramidal cells only in the aged mice showing a reduced lea...

journal_title：Brain research

authors： Kubo KY,Iwaku F,Watanabe K,Fujita M,Onozuka M

更新日期：2005-09-28 00:00:00

abstract：:The effects of injecting cholecystokinin (CCK) into the third ventricle or into selected hypothalamic sites on electrical firing rate of sympathetic nerves to interscapular brown fat (IBAT) has been investigated in anesthetized rats. The hypothesis for these experiments was that there was a reciprocal relationship bet...

journal_title：Brain research

authors： Yoshimatsu H,Egawa M,Bray GA

更新日期：1992-12-04 00:00:00

abstract：:The non-cholinergic slow excitatory postsynaptic potential (EPSP) in the guinea pig inferior mesenteric ganglion (IMG) is believed to be mediated by substance P (SP). Yet, in ganglia of guinea pigs treated with capsaicin (50, 100, or 350 mg/kg, s.c.), a compound that depletes SP from sensory neurons, slow EPSPs were o...

journal_title：Brain research

authors： Peters S,Kreulen DL

更新日期：1984-06-11 00:00:00

abstract：:The ionic basis of norepinephrine (NE) action was studied with intracellular recording techniques in the rat hippocampal slice. Topical application of NE caused, in CA1 neurons, a 3-4 mV hyperpolarization associated with a 10-20% decrease in input resistance. This effect was accompanied by a decrease in spontaneous ac...

journal_title：Brain research

authors： Segal M

更新日期：1981-02-09 00:00:00

abstract：:Noradrenergic, serotoninergic and peptidergic nerves have been demonstrated in perivascular plexuses of vasa nervorum of sympathetic, parasympathetic and somatic nerve trunks. 5-Hydroxytryptamine-, vasoactive intestinal polypeptide- and substance P-containing fibers were found by immunohistochemistry to variable exten...

journal_title：Brain research

authors： Appenzeller O,Dhital KK,Cowen T,Burnstock G

更新日期：1984-06-25 00:00:00

abstract：:The Leu-enkephalin dalargin does not normally penetrate the blood brain barrier when given intravenously. Drug targeting to the brain was investigated by using poly(butylcyanoacrylate) nanoparticles which were coated with polysorbate 80. When injected intravenously in mice, dalargin-loaded nanoparticles coated with th...

journal_title：Brain research

authors： Schröder U,Sabel BA

更新日期：1996-02-26 00:00:00

abstract：:A sample of 302 neurons in rat hindlimb granular cortex was studied between 2 and 3 weeks after transection and ligation of the sciatic nerve. These neurons were compared to a control sample obtained from normal rats under similar experimental conditions. After sciatic nerve transection the proportion of neurons drive...

journal_title：Brain research

authors： Dykes RW,Lamour Y

更新日期：1988-05-24 00:00:00

abstract：:The blood-brain barrier (BBB) permeability primarily increases in cerebral venules during acute hypertension. Methyl-β-cyclodextrin (MβCD), a cholesterol-depleting agent, decreases the expression of caveolins disrupting caveolar structures. We aimed to determine the effects of MβCD on the BBB permeability of angiotens...

journal_title：Brain research

authors： Atış M,Akcan U,Uğur Yılmaz C,Orhan N,Düzgün P,Deniz Ceylan U,Arıcan N,Karahüseyinoğlu S,Nur Şahin G,Ahıshalı B,Kaya M

更新日期：2019-07-15 00:00:00

abstract：:Neurotensin (NT) is an endogenous brain tridecapeptide for which high affinity binding sites exist in the central nervous system. We have investigated the effects of NT incubation with rat neostriatal slices on calcium/calmodulin (Ca/CaM)-dependent protein phosphorylation. Slices were incubated with NT (5 or 50 nM) fo...

journal_title：Brain research

authors： Kasckow J,Cain ST,Nemeroff CB

更新日期：1991-04-05 00:00:00