Involvement of nigrostriatal dopamine neurons in the contraversive rotational behavior evoked by electrical stimulation of the lateral hypothalamus.

abstract：:We examined whether mild brain hypothermia during pretreatment with sublethal 2-min ischemia affected the tolerance to subsequent lethal 5-min ischemia. The neuronal densities in the hippocampal CA1 sector of gerbils preconditioned at mild brain hypothermia (32% of normal) were significantly lower than those in gerbil...

journal_title：Brain research

authors： Wada K,Miyazawa T,Katoh H,Nomura N,Yano A,Shima K,Chigasaki H

更新日期：1997-01-23 00:00:00

abstract：:Previous studies found that injection of the GABA uptake inhibitor nipecotic acid into the nucleus tractus solitarius (NTS) increases arterial pressure. This effect of nipecotic acid was not antagonized by the selective GABAA receptor blocking agent bicuculline, suggesting that the action of nipecotic acid was mediate...

journal_title：Brain research

authors： Sved AF,Sved JC

更新日期：1990-09-03 00:00:00

abstract：:Reverse transcription-polymerase chain reaction demonstrated the expression of heme oxygenase-1 and heme oxygenase-2 (HO-2) mRNA in the cochlea, but the former was considered to be much lower than the latter. The HO-2-like immunoreactivity was observed mainly in supporting cells in the organ of Corti and in the spiral...

journal_title：Brain research

authors： Watanabe K,Oshima T,Kobayashi T,Ikeda K

更新日期：2003-03-14 00:00:00

abstract：:In the present study, we characterized the evoked electrical activity from T(13) to S(2) dorsal roots (DRs) during glass probe-stimulation of the vagina-cervix-uterus junction (VCUJ) of female Wistar rats. The results showed that gentle stimulation of VCUJ evoked high-amplitude electrical activity in L(3) and L(6) DRs...

journal_title：Brain research

authors： Tovar A,Lara-Garcia M,Cruz Y,Pacheco P

更新日期：2013-02-16 00:00:00

abstract：:Hypoxia-induced apoptosis of retinal ganglion cells (RGCs) is the major cause of progressive vision loss in numerous retinal diseases, including glaucoma and diabetic retinopathy. Taurine is a naturally occurring free amino acid that has been shown to have neurotrophic and neuroprotective properties in the retina. We ...

journal_title：Brain research

authors： Chen K,Zhang Q,Wang J,Liu F,Mi M,Xu H,Chen F,Zeng K

更新日期：2009-07-07 00:00:00

abstract：:Alpha-synuclein is a brain presynaptic protein that is linked to familiar early onset Parkinson's disease and it is also a major component of Lewy bodies in sporadic Parkinson's disease and other neurodegenerative disorders. Alpha-synuclein expression increases in substantia nigra of both MPTP-treated rodents and non-...

journal_title：Brain research

authors： Gómez-Santos C,Ferrer I,Reiriz J,Viñals F,Barrachina M,Ambrosio S

更新日期：2002-05-10 00:00:00

abstract：:The number of viable neurones calculated as soon as adult mollusc ganglia tissue was digested and over different periods of cultivation, show that elevated K+ prevents degradation of intercellular contacts, preserves neurones against lysis, prolongs the time course of neurone survival in culture and inhibits neurite f...

journal_title：Brain research

authors： Kostenko MA,Tretjak NN,Musienko VS

更新日期：1982-03-18 00:00:00

abstract：:Projections from the hypothalamus to cells of origin of the greater petrosal nerve were studied by the HRP and autoradiographic techniques in the rat. After an injection of [3H]amino acids into the hypothalamus and an application of HRP to the greater petrosal nerve, we found that a compact group of HRP-labeled neuron...

journal_title：Brain research

authors： Hosoya Y,Matsushita M,Sugiura Y

更新日期：1984-01-02 00:00:00

abstract：:Secretion of calcitonin gene-related peptide (CGRP) was studied with the model system of dispersed adult rat trigeminal ganglion cells. Veratridine stimulated secretion of CGRP immunoreactivity. Tetrodotoxin and local anesthetics inhibited veratridine-stimulated peptide secretion. These observations implicate sodium c...

journal_title：Brain research

authors： Peterfreund RA,Vale WW

更新日期：1986-08-13 00:00:00

abstract：:Immunofluorescence on primary dissociated rat neuronal cultures (cortical, hippocampal, and cerebellar) and organotypic hippocampal cultures was used to investigate the pattern of distribution of cell-surface amyloid protein (APP). Antibodies directed against the extracellular (N-terminal) portion of APP or against th...

journal_title：Brain research

authors： Storey E,Beyreuther K,Masters CL

更新日期：1996-10-07 00:00:00

abstract：:This study examined the projection from the rostral nucleus of the solitary tract (rNST) to the medial parabrachial nucleus (mPBN) in male Wistar rats using DiI as a retrograde tracer and biotinylated dextran as an anterograde tracer. Following successful unilateral injection of DiI into the mPBN (n = 8), retrogradely...

journal_title：Brain research

authors： Williams JB,Murphy DM,Reynolds KE,Welch SJ,King MS

更新日期：1996-10-21 00:00:00

abstract：:To examine the effect of development on rabbit brain insulin and insulin-like growth factor (IGF) receptor expression, we characterized and quantitated receptor mRNAs by Northern blot analysis and affinity-labeled ligand bound receptors by SDS-PAGE and autoradiography. At various stages of development ranging from 23 ...

journal_title：Brain research

authors： Devaskar SU,Sadiq HF,Holtzclaw L,George M

更新日期：1993-03-05 00:00:00

abstract：:Single episodes of arousal of Syrian hamsters 2 h before projected activity onset (i.e., CT 10) phase-advanced their free-running circadian rhythm of wheel-running. Serial arousal once every 23 h or once every 23.5 h for 7 days caused large composite phase-advances to the wheel-running rhythm, the latter period being ...

journal_title：Brain research

authors： Sumova A,Maywood ES,Selvage D,Ebling FJ,Hastings MH

更新日期：1996-02-12 00:00:00

abstract：:Microinjection of cholinergic agonists into the pontine tegmentum was used to evoke a state which was polygraphically and behaviorally similar to desynchronized (D) sleep. This study was designed to test the hypothesis that the production of this pharmacologically induced D sleep-like state (D-ACh) was dependent upon ...

journal_title：Brain research

authors： Baghdoyan HA,Rodrigo-Angulo ML,McCarley RW,Hobson JA

更新日期：1987-06-30 00:00:00

abstract：:The effects of selective axotomy of serotoninergic neurons produced by an intracerebroventricular injection of 5,7-dihydroxytryptamine (200 micrograms free base) on 5-HT1B binding sites labeled with S-CM-G-[125I]TNH2 were investigated by quantitative autoradiography in the rat brain. Results show, 21 days after surger...

journal_title：Brain research

authors： Manrique C,Segu L,Héry F,Héry M,Faudon M,François-Bellan AM

更新日期：1993-10-01 00:00:00

abstract：:Electrical stimulation of the retina evokes at the optic tract level rhythmic bursts of activity whose temporal structure is predictable from the polarity of the stimulation and the receptive field type. The reaction of lateral geniculate units to this input was studied in fast and slow relay cells as well as in inter...

journal_title：Brain research

authors： Molotchnikoff S,Lachapelle P

更新日期：1978-08-18 00:00:00

abstract：:Considerable research indicates that long-term synaptic plasticity in the amygdala underlies the acquisition of emotional memories, including those learned during Pavlovian fear conditioning. Much less is known about the synaptic mechanisms involved in other forms of associative learning, including extinction, that up...

journal_title：Brain research

authors： Maren S

更新日期：2015-09-24 00:00:00

abstract：:The effects of duloxetine were examined on cloned Kv4.3 channels stably expressed in CHO cells using the whole-cell patch-clamp technique. Duloxetine decreased the peak amplitude of Kv4.3 currents with an acceleration of the decay rate of current inactivation in a concentration-dependent manner. The IC(50) values requ...

journal_title：Brain research

authors： Choi JS,Hahn SJ

更新日期：2012-07-23 00:00:00

abstract：:Neuropathic pain remains a major complication of various forms of injury to peripheral nerves in humans. Recently, 2 models of peripheral mononeuropathy in the rat have been described which closely resemble the human condition. Bennett and Xie3 described one model induced by the placement of 4 loose ligatures around t...

journal_title：Brain research

authors： Dougherty PM,Garrison CJ,Carlton SM

更新日期：1992-01-20 00:00:00

abstract：:Both glial cell line-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF) can protect nigrostriatal dopaminergic neurons from neurotoxins in rodent and monkey models of Parkinson's disease (PD). These two neurotrophic factors are usually tested individually. This study was designed to compar...

journal_title：Brain research

authors： Sun M,Kong L,Wang X,Lu XG,Gao Q,Geller AI

更新日期：2005-08-09 00:00:00

abstract：:A technique is described for the autoradiographic localization of D-glucose inhibitable cytochalasin B binding in fresh frozen sections of rat brain. The technique has been used to study the regional distribution of glucose transporter proteins. Binding sites within the cerebellum and hippocampus were more concentrate...

journal_title：Brain research

authors： Tucker SP,Cunningham VJ

更新日期：1988-05-31 00:00:00

abstract：:Repeated sensory exposure through frequent consumption of certain foods leads to changes in the processing of sensory cues. We investigated the influence of frequent minty chewing gum consumption on the neurobehavioral processing of intranasal trigeminal and olfactory stimuli. fMRI responses to a trigeminal minty odor...

journal_title：Brain research

authors： Han P,Penzler M,Jonathan W,Hummel T

更新日期：2020-03-01 00:00:00

abstract：:Sleep is posited to be a fundamental property of groups of highly interconnected neurons and regulated in part by activity-dependent sleep regulatory substances such as tumor necrosis factor alpha (TNFalpha). We show that the unilateral local application of TNFalpha onto the somatosensory cortex of rats induced state-...

journal_title：Brain research

authors： Yoshida H,Peterfi Z,García-García F,Kirkpatrick R,Yasuda T,Krueger JM

更新日期：2004-05-29 00:00:00

abstract：:We have explored the potential neuroprotective effect of local lentiviraly-mediated overexpression of nerve growth factor (NGF) on in vivo long-term potentiation (LTP) in the rat hippocampus under pathological conditions. The suspension of lentiviral particles was prepared using a genetic construct containing the huma...

journal_title：Brain research

authors： Uzakov SS,Ivanov AD,Salozhin SV,Markevich VA,Gulyaeva NV

更新日期：2015-10-22 00:00:00

abstract：:The postnasal development of the Na-independent [3H]glutamate binding sites, which exhibit some characteristics of postsynaptic glutamate receptors, has been studied in rat hippocampal membranes. The amount of binding sites (expressed in pmol/hippocampus) represents 4% of the adult level at postnatal day (PND) 4, incr...

journal_title：Brain research

authors： Baudry M,Arst D,Oliver M,Lynch G

更新日期：1981-01-01 00:00:00

abstract：:The current experiment aimed to explore age differences in brain activity associated with successful memory retrieval in older adults with different levels of executive functioning, at different levels of task demand. Memory performance and fMRI activity during a recognition task were compared between a young group an...

journal_title：Brain research

authors： Angel L,Bastin C,Genon S,Salmon E,Fay S,Balteau E,Maquet P,Luxen A,Isingrini M,Collette F

更新日期：2016-01-15 00:00:00

abstract：:Spectrally opponent processes of ON-type retinal ganglion cells and the blue preference behavior were identified by parallel physiological and behavioral experiments in Rana pipiens. Spectral opponency of retinal ON-units was measured by recording from optic nerve terminals in the anterior thalamus, while the retina w...

journal_title：Brain research

authors： Kicliter E,Kay CJ,Chino YM

更新日期：1981-04-06 00:00:00

abstract：:Microinjections of the substance P (SP) antagonist (D-pro2,D-phe7,D-trp9)-SP, or the gamma-aminobutyric acid (GABA) agonist, muscimol, into the entopeduncular nucleus reduced muscle tone in genetically spastic rats in a dose- and time-dependent manner. Similar injections into the ventral thalamus, zona incerta or amyg...

journal_title：Brain research

authors： Turski L,Klockgether T,Turski WA,Schwartz M,Sontag KH

更新日期：1990-02-19 00:00:00

abstract：:Multiple dose administration of methamphetamine (MA) results in long-lasting toxic effects in the nigrostriatal dopaminergic system. These effects are considered to be primarily due to oxidative damage mediated by increased production of hydrogen peroxide or other reactive oxygen species in the dopaminergic system. Th...

journal_title：Brain research

authors： Kim HC,Jhoo WK,Choi DY,Im DH,Shin EJ,Suh JH,Floyd RA,Bing G

更新日期：1999-12-18 00:00:00

abstract：:Following lesions of the pyramidal tract in hamsters, retrograde changes were studied in the sensorimotor cortex and in the pyramidal tract axons proximal to the lesion, at survival times ranging from 2 weeks to 14 months. Severe cell shrinkage occurred in layer 5 pyramidal neurons as early as 2 weeks, but there was n...

journal_title：Brain research

authors： Kalil K,Schneider GE

更新日期：1975-05-16 00:00:00