Abstract:
:Repeated sensory exposure through frequent consumption of certain foods leads to changes in the processing of sensory cues. We investigated the influence of frequent minty chewing gum consumption on the neurobehavioral processing of intranasal trigeminal and olfactory stimuli. fMRI responses to a trigeminal minty odor (L-menthol), a non-trigeminal minty odor (L-carvone), and a non-trigeminal non-minty odor (strawberry) were assessed in 29 young adults (mean age = 23 years, SD = 4.3 years; mean BMI = 22.7, SD = 1.9; thirteen females), who were divided into a minty chewing gum high frequency (N = 18) and a low infrequency (N = 11) groups based on their self-reported frequency of chewing gum consumption. Participants' performance for odor lateralization, ratings for perceived odor intensity, pleasantness, familiarity, and pungency were also collected. Compared to the low frequency group, the high frequency group rated L-menthol as more familiar and performed better during the L-menthol lateralization test. The high frequency group compared to low frequency group showed stronger activation in trigeminal and somatosensory brain regions during perception of trigeminal component. These findings suggest an association between frequent minty odor exposure and increased neurobehavioral sensitivity to intranasal trigeminal stimulation.
journal_name
Brain Resjournal_title
Brain researchauthors
Han P,Penzler M,Jonathan W,Hummel Tdoi
10.1016/j.brainres.2020.146663subject
Has Abstractpub_date
2020-03-01 00:00:00pages
146663eissn
0006-8993issn
1872-6240pii
S0006-8993(20)30019-6journal_volume
1730pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The aim of the present study was to evaluate p38 MAPK activation following focal stroke and determine whether SB 239063, a novel second generation p38 inhibitor, would directly attenuate early neuronal injury. Following permanent middle cerebral artery occlusion (MCAO), brains were dissected into ischemic and non-isch...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)03228-5
更新日期:2001-02-16 00:00:00
abstract::The primary objective of this study was to test the hypothesis that intravenous administration of autologous bone marrow cells could improve functional recovery after middle cerebral artery occlusion (MCAO) for 45 min in the rat and to determine specific time windows for efficacy. Mononuclear cells from autologous bon...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2003.09.084
更新日期:2004-05-08 00:00:00
abstract::Previous research has suggested the potential involvement of the hypothalamic-pituitary-adrenal (HPA) axis in psychostimulant reinforcement. In particular, we have found significant correlations between electric footshock-induced increases in plasma corticosterone and the acquisition, or lack thereof, of intravenous c...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00206-5
更新日期:1996-05-25 00:00:00
abstract::Neurofilaments were assembled in vitro from the high speed supernatant of mammalian CNS homogenate in a disassembly buffer containing 4-morpholine-ethane sulfonic acid, MgCl2 and EGTA at 4 degrees C in the presence of 4 M glycerol. The assembled neurofilaments were depolymerized by dialysis against the disassembly buf...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(87)80010-0
更新日期:1987-07-01 00:00:00
abstract::Mesenchymal stem cell (MSC) transplantation has been reported to improve neurologic function after ischemic injury. However, the detailed mechanisms by which MSCs promote functional recovery are not fully understood. Interleukin-10 (IL-10) is a well-known anti-inflammatory cytokine with neuroprotective effects with re...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.03.080
更新日期:2010-06-02 00:00:00
abstract::Involvement of N-methyl-D-aspartate (NMDA) receptor complex and 5-hydroxytryptamine3 (5-HT3) receptors in state-dependent learning (SDL) induced by ethanol (EtOH) was investigated in the step-through passive avoidance task in rats. Pre-training injections of EtOH or MK-801 reduced step-through latency in the test sess...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)01040-8
更新日期:1996-01-15 00:00:00
abstract::Infusion of basic fibroblast growth factor (bFGF) prevents the loss of cholinergic neurons in the septum/diagonal band of broca following fimbria-fornix transection. However, an in vivo test of whether bFGF will also rescue injured non-cholinergic or cortical neurons has not been carried out. Previous studies have sho...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)91707-l
更新日期:1992-09-25 00:00:00
abstract::Conditions for the stimulation of taurine release by illumination or increased K+ concentrations were established. The effect of Mg2+, ruthenium red and verapamil on taurine release induced by both procedures was compared. All these agents antagonize Ca2+-dependent release of neurotransmitters. Illumination-induced re...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90054-8
更新日期:1976-09-03 00:00:00
abstract::The involvement of striatal cholinergic neurons in the release of dopamine (DA) elicited by the mu-opioid receptor agonist DAGO ([D-Ala2, NMePhe4-Gly5(ol)]enkephalin) was explored. The striatal release of DA was measured by microdialysis in rats anesthetized with chloral hydrate. When infused in the striatum, through ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/S0006-8993(96)01319-4
更新日期:1997-02-28 00:00:00
abstract::The action of the epileptogenic agent pentylenetetrazol (PTZ) on a cloned potassium channel of the rat brain was studied. The Kv1.1 channel was expressed in oocytes of Xenopus laevis and potassium currents were investigated in outside-out and inside-out membrane patches. The results show that PTZ increased the multi-c...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00181-3
更新日期:1996-05-25 00:00:00
abstract::Rats were trained to lever-press for lateral hypothalamic electrical stimulation, and tested following ventral tegmental microinjections of morphine, delta ([D-Pen2,D-Pen5]enkephalin: DPDPE), or kappa (U-50, 488H) receptor agonists or saline. Across the range of effective stimulation frequencies, morphine (8 nmol) and...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90821-3
更新日期:1987-10-13 00:00:00
abstract::We studied the propagation of spike discharges and the changes in local cerebral blood flow (LCBF) by means of the electroencephalogram (EEG) and autoradiographs to elucidate the underlying mechanism and the propagation pathway in rats with limbic seizures. Seizures were induced by the unilateral microinjection of kai...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91923-2
更新日期:1994-01-21 00:00:00
abstract::The in vitro model presented provides an approach to study the nature of cell volume control as well as of swelling mechanisms under pathophysiological conditions. Pertinent parameters of cell volume control can be analyzed in isolation due to a virtually infinite extracellular environment precluding secondary effects...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)90180-4
更新日期:1983-11-21 00:00:00
abstract::We compared the relative abilities of a series of calmodulin inhibitors and protein kinase C inhibitors to influence 45Ca2+ influx through voltage-dependent Ca2+ channels in PC12, a clonal neural cell line. K+-depolarization-dependent 45Ca2+ uptake was reduced by the calmodulin inhibitors calmidazolium, trifluoperazin...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)91403-x
更新日期:1987-02-24 00:00:00
abstract::The active and passive properties of petrosal ganglion sensory neurons with axons in the glossopharyngeal nerve were examined with intracellular microelectrodes in an in vitro preparation. Glossopharyngeal neurons could be classified into two groups: H-cells showing an inflexion or hump on the falling phase of the spi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)91418-1
更新日期:1987-01-20 00:00:00
abstract::Adult male guinea pigs were castrated and 24 h later injected with [3H]dihydrotestosterone. Their pituitary glands were then processed for autoradiographic and immunocytochemical analyses. Three percent of the parenchymal cells in the pars distalis were radiolabelled. These cells were primarily gonadotrophs; a small p...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90456-7
更新日期:1986-01-08 00:00:00
abstract::The two human brain beta-galactosidases were solubilized and fractionated by Sephadex G-200 gel filtration, free from each other. Substrate specificities of the two enzymes were examined for galactosylceramide, lactosyl-[N-stearoyl]ceramide, lactosyl-[N-lignoceroyl]ceramide, galactosyl-N-acetylgalactosaminyl-[N-stearo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(77)90298-0
更新日期:1977-02-18 00:00:00
abstract::parkin is the most frequent causative gene among familial Parkinson's disease (PD). Although parkin deficiency induces autosomal recessive juvenile parkinsonism (AR-JP, PARK2) in humans, parkin knockout (PKO) mice consistently show few signs of dopaminergic degeneration. We aimed to directly measure evoked extracellul...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.06.065
更新日期:2010-09-17 00:00:00
abstract::Astrocytes exhibit an important role in neural lipid metabolism for the regulation of energy balance to supply fatty acids (FAs) and ketone bodies to other neural cells. Lipid droplets (LDs) consisting of neutral- and phospho-lipids increase in the brains of patients with neurodegenerative diseases, such as Alzheimer'...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2019.146484
更新日期:2019-12-15 00:00:00
abstract::A direct projection from rat mesencephalic trigeminal nucleus (Vme) neurons to the hypoglossal nucleus (XII) motoneurons was studied using a double labeling method of anterogradely biotinylated dextran amine (BDA) tracing combined with retrogradely horseradish peroxidase (HRP) transport at both light and electron micr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02911-0
更新日期:2001-10-26 00:00:00
abstract::It has been accepted that the descending system from the nucleus locus coeruleus (LC)/nucleus subcoeruleus (SC) plays a significant role in spinal nociceptive processing. The present study was designed to examine modulation of nociceptive processing in the caudal part of the trigeminal sensory nuclear complex, the tri...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2003.09.023
更新日期:2003-12-12 00:00:00
abstract::Rabbits reared from birth in stroboscopic illumination have no experience of visual motion. In primary visual cortex of these animals there is a large reduction in the number of cells which are direction selective. This result, contrary to previous reports, shows that the rabbit visual system can be modified by early ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(81)90099-7
更新日期:1981-01-01 00:00:00
abstract::The relationship between placental antigen X-P2 (PAX)-immunoreactive glomeruli and intensely acetylcholinesterase-reactive (IAE) patchy regions was evaluated by comparison of neighboring cryostat sections of the rat olfactory bulb. Both groups of distribution show similar necklace patterns. Each IAE region consists of...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)90440-x
更新日期:1993-07-30 00:00:00
abstract::This study examines projection to the cerebellar flocculus of eye movement-related neurons in the median and paramedian part of the cat pontine tegmentum between the trochlear and the abducens nucleus. They were identified by rhythmic activity related to horizontal vestibular nystagmus induced by sinusoidal rotation. ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90465-5
更新日期:1980-02-10 00:00:00
abstract::Dehydroepiandrosterone (DHEA) modulates neurogenesis, neuronal function, neuronal survival and metabolism, enhancing mitochondrial oxidative capacity. Glucose deprivation and hypometabolism have been implicated in the mechanisms that mediate neuronal damage in neurological disorders, and some studies have shown that t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.05.014
更新日期:2016-08-01 00:00:00
abstract::The subthalamic nucleus receives serotonergic projections from the dorsal raphe nucleus. However, the role of serotonergic innervation in the activity of subthalamic neurons in vivo is unknown. The aim of the present work is to study the changes in the firing of subthalamic neurons in rats with 5,7-dihydroxytryptamine...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.02.052
更新日期:2007-05-29 00:00:00
abstract::Cytotoxic effects of L-glutamate and related compounds were investigated on rat glioma C6 cells in vitro. Within 12-24 h, addition of glutamate to the culture medium, resulted in degeneration of the C6 cells. The ED50 for glutamate-induced damage was about 4 mM. Seventeen structural analogues of glutamate, including a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)91222-8
更新日期:1984-06-15 00:00:00
abstract::Generation and persistence of tinnitus following hearing loss may be due to aberrant engagement of attention. Here, functional MRI was used to determine differences in auditory and visual attention processing in adults with tinnitus and hearing loss compared to two age-matched control groups, one with matched hearing ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2015.05.010
更新日期:2015-09-16 00:00:00
abstract::Although it is generally believed that the central projections of the retina in birds are entirely crossed, using wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) as an anterograde tracer, we have found that in normal posthatched chicks there is a small ipsilateral retinofugal projection to the dience...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(83)90124-4
更新日期:1983-10-01 00:00:00
abstract::Glutamate is an excitatory neurotransmitter implicated in the pathogenesis of psychiatric disorders. Glutamate results in the activation of an enzyme called glycogen synthase kinase-3 (GSK-3) acting through N-methyl-d-aspartate (NMDA) receptors. Impaired expression of GSK-3 affects behavior and neurochemicals level in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2018.10.002
更新日期:2019-02-01 00:00:00