Abstract:
:The number of viable neurones calculated as soon as adult mollusc ganglia tissue was digested and over different periods of cultivation, show that elevated K+ prevents degradation of intercellular contacts, preserves neurones against lysis, prolongs the time course of neurone survival in culture and inhibits neurite formation. K+ depolarizing effect is maintained throughout the whole course of cultivation; when elevated K+ is substituted by normal K+ the resting potential of neurones recovers. The effect of elevated K+ on neurone survival and the capability for neurite formation is not due to membrane depolarization, but seems to be related to an influence on intracellular ionic homeostasis.
journal_name
Brain Resjournal_title
Brain researchauthors
Kostenko MA,Tretjak NN,Musienko VSdoi
10.1016/0006-8993(82)90044-0subject
Has Abstractpub_date
1982-03-18 00:00:00pages
183-92issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(82)90044-0journal_volume
236pub_type
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