Serotonin and norepinephrine in the spinal cord of man.

abstract：:At present, the ability of polyunsaturated fatty acids (PUFAs) to regulate individual glutamate transporter subtypes is poorly understood and very little information exists on the mechanism(s) by which PUFAs achieve their effects on the transport process. Here we investigate the effect of cis-4,7,10,13,16,19-docosahex...

journal_title：Brain research

authors： Berry CB,Hayes D,Murphy A,Wiessner M,Rauen T,McBean GJ

更新日期：2005-03-10 00:00:00

abstract：:The purpose of this study was to determine if motoneurons in the spinal ventral horn express the muscarinic m2 acetylcholine receptor. Motoneurons were retrogradely labelled in adult rats by intramuscular injection of Fluorogold and examined with confocal microscopy for evidence of immunoreactivity for the receptor. T...

journal_title：Brain research

authors： Welton J,Stewart W,Kerr R,Maxwell DJ

更新日期：1999-01-30 00:00:00

abstract：:Rhythmic caffeine hyperpolarizations generated in bullfrog sympathetic ganglion cells are assumed to be caused by periodic increase in gK due to rise in [Ca2+]i7--9,13. Caffeine-induced outward currents seem to be composed of two different components, which show different pharmacological natures and also different dep...

journal_title：Brain research

authors： Koketsu K,Akasu T,Miyagawa M

更新日期：1982-07-15 00:00:00

abstract：:Even though several of RFamide peptides have been shown to modify memory and learning processes in different species, almost nothing is known regarding cognitive effects of recently discovered neuropeptide QRFP. Considering multiple physiological functions of QRFP, localization of QRFP-synthesizing neurons in the hypo...

journal_title：Brain research

authors： Zagorácz O,Ollmann T,Péczely L,László K,Kovács A,Berta B,Kállai V,Kertes E,Lénárd L

更新日期：2020-01-15 00:00:00

abstract：:Oxidative stress plays an important role in neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease. Methamphetamine (METH) is an amphetamine analog that causes degeneration of the dopaminergic system in mammals and subsequent oxidative stress. In our present study, we have used immortalized hu...

journal_title：Brain research

authors： Zhang X,Banerjee A,Banks WA,Ercal N

更新日期：2009-06-12 00:00:00

abstract：:Intracellular recordings from CA3b/c neurons in rat hippocampal slices showed that reduction of the extracellular Cl- concentration from 136 to 53 mM produced a positive (+10 mV) shift in the reversal potential of GABAergic inhibitory postsynaptic potentials (IPSPs). This shift was not significantly different from the...

journal_title：Brain research

authors： Chamberlin NL,Dingledine R

更新日期：1988-03-29 00:00:00

abstract：:Notch signaling is a highly conserved pathway that regulates cell fate decisions during embryonic development. We have recently identified that in ischemic stroke, activity of γ-secretase and the resulting Notch activation may endanger neurons by modulating NF-κB and HIF-1α pathways. Notch signaling can also modulate ...

journal_title：Brain research

authors： Cheng YL,Choi Y,Seow WL,Manzanero S,Sobey CG,Jo DG,Arumugam TV

更新日期：2014-10-24 00:00:00

abstract：:Cytochrome P45011B1 (11 beta-hydroxylase) was detected in the brain of male rats by in situ hybridization methods. Normal Sprague-Dawley rats were compared to the transgenic strain TGR(mRen2)27, characterized by the expression of the murine Ren-2d renin gene and the development of severe hypertension. Specific ribopro...

journal_title：Brain research

authors： Erdmann B,Gerst H,Lippoldt A,Bülow H,Ganten D,Fuxe K,Bernhardt R

更新日期：1996-09-09 00:00:00

abstract：:The primary objective of this study was to test the hypothesis that intravenous administration of autologous bone marrow cells could improve functional recovery after middle cerebral artery occlusion (MCAO) for 45 min in the rat and to determine specific time windows for efficacy. Mononuclear cells from autologous bon...

journal_title：Brain research

authors： Iihoshi S,Honmou O,Houkin K,Hashi K,Kocsis JD

更新日期：2004-05-08 00:00:00

abstract：:The pleiotropic cytokine tumor necrosis factor-alpha (TNFalpha) is implicated in the development of persistent pain through its actions in the periphery and in the central nervous system (CNS). Activation of the alpha(2)-adrenergic receptor is associated with modulation of pain, possibly through its autoregulatory eff...

journal_title：Brain research

authors： Covey WC,Ignatowski TA,Knight PR,Spengler RN

更新日期：2000-03-17 00:00:00

abstract：:There are marked increases in noradrenaline (NA) release during emergence from general anesthesia induced with volatile anesthestics. These changes in NA in the posterior hypothalamus of the rat were assessed by intracranial microdialysis. Sevoflurane and halothane in equipotent concentrations were used to obtain the ...

journal_title：Brain research

authors： Chave S,Kushikata T,Ohkawa H,Ishiara H,Grimaud D,Matsuki A

更新日期：1996-01-15 00:00:00

abstract：:A series of ballistic, unidirectional arm movements were studied to evaluate the electromyographic (EMG) and neuromuscular force patterns that occur when a limb is unexpectedly perturbed. Multiple training trials were continued with a control load spring attached to the apparatus until a pre-specified criterion for le...

journal_title：Brain research

authors： Richardson C,Simmons RW

更新日期：1985-09-23 00:00:00

abstract：:125I-alpha-Scorpion toxin (alpha-ScTx) binds to a component of the voltage-sensitive Na+ channel. We have previously shown that receptor capacity on dissociated mouse brain cells increases between days 12 and 19 of fetal life as does the expression of neurotoxin-sensitive 22Na+ influx. In the present study we have inv...

journal_title：Brain research

authors： Martin-Moutot N,Cau P,Berwald-Netter Y,Couraud F

更新日期：1987-03-01 00:00:00

abstract：:Experimental studies and clinical observations show that spinal cord lesions are greatly enlarged by a process called secondary cell death. A detailed understanding of the molecular and cellular processes underlying these events is still lacking. In clinical studies using methylprednisolone in spinal cord injured pati...

journal_title：Brain research

authors： Bartholdi D,Schwab ME

更新日期：1995-02-20 00:00:00

abstract：:In scopolamine-treated (5.0 mg/kg, s.c.) rats hippocampal rhythmical slow activity (RSA) and neocortical low voltage fast activity (LVFA) occur only in close correlation with head movements, spontaneous changes in posture, or locomotion (Type I behavior). Previous work indicates that such scopolamine-resistant RSA and...

journal_title：Brain research

authors： Watson NV,Hargreaves EL,Penava D,Eckel LA,Vanderwolf CH

更新日期：1992-11-27 00:00:00

abstract：:In the present study, we used a repeated restraint stress animal model to observe the changes in the expression of brain-derived neurotrophic factor (BDNF) and B cell lymphoma protein-2 (Bcl-2) in hippocampal neurons of rats, monitored the time course of the expression over 3 weeks post-stress period, and examined the...

journal_title：Brain research

authors： Luo C,Xu H,Li XM

更新日期：2004-10-29 00:00:00

abstract：:Activity produced by direct microelectrophoretic application of glutamate onto 19 convergent neurones in trigeminal nucleus caudalis, was strongly depressed during and after the application of heterotopic noxious conditioning stimuli: noxious heat (52 degrees C) applied to the tail, noxious pinches applied to the tail...

journal_title：Brain research

authors： Villanueva L,Cadden SW,Le Bars D

更新日期：1984-10-29 00:00:00

abstract：:Intraocular injections of tetrodotoxin were used to block activity for 27 days in normal fish and for the first 27 or 31 days of regeneration in fish with one optic nerve crushed. Synaptic activity was then assessed by a current source-density analysis of field potentials evoked by optic nerve shock at different times...

journal_title：Brain research

authors： Schmidt JT,Edwards DL,Stuermer C

更新日期：1983-06-13 00:00:00

abstract：:Projections from the hypothalamus to cells of origin of the greater petrosal nerve were studied by the HRP and autoradiographic techniques in the rat. After an injection of [3H]amino acids into the hypothalamus and an application of HRP to the greater petrosal nerve, we found that a compact group of HRP-labeled neuron...

journal_title：Brain research

authors： Hosoya Y,Matsushita M,Sugiura Y

更新日期：1984-01-02 00:00:00

abstract：:Bilateral quisqualic acid-induced lesions of the nucleus basalis magnocellularis (nbm) in rats disrupted the expression of latent inhibition, a phenomenon thought to be dependent upon selective attention processes. Since grafts of adrenal chromaffin cells to the cerebral cortex of nbm-lesioned rats have been shown to ...

journal_title：Brain research

authors： Welner SA,Rousse I,Rochford J

更新日期：1995-02-13 00:00:00

abstract：:Electrical synaptic transmission via gap junctions has become an accepted feature of neuronal communication in the mammalian brain, and occurs often between dendrites of interneurons in major brain structures, including the hippocampus. Electrical and dye-coupling has also been reported to occur between pyramidal cell...

journal_title：Brain research

authors： Nagy JI

更新日期：2012-12-03 00:00:00

abstract：:Cerebral cortex membranes from rats habituated to manipulations preceding decapitation (habituated rats) had 40% higher GABA binding than membranes from naive animals. Diazepam (5 X 10(-6) M), added to membranes from naive rats, increased GABA binding to the level of habituated rats, but failed to induce any further i...

journal_title：Brain research

authors： Biggio G,Concas A,Serra M,Salis M,Corda MG,Nurchi V,Crisponi C,Gessa GL

更新日期：1984-07-02 00:00:00

abstract：:We examined the degree of oxidative damage to the brain of mice transgenic for the mutation responsible for Huntington's disease. We found that there is a progressive increase in striatal lipid peroxidation (LP), that parallels the worsening of the neurological phenotype. We consider that these transgenic mice may pro...

journal_title：Brain research

authors： Pérez-Severiano F,Ríos C,Segovia J

更新日期：2000-04-17 00:00:00

abstract：:Pars interpolaris of the spinal trigeminal nucleus of kittens has been studied with the electron microscope at birth and at several subsequent ages during the first month of life. Attention has been given to ultrastructural maturational changes that occur in this neuropil, especially events in synaptogenesis. The resu...

journal_title：Brain research

authors： Dunn RC,Westrum LE

更新日期：1978-03-31 00:00:00

abstract：:Our previous studies have indicated that oxygen radicals, produced during reoxygenation following short-term arterial hypoxia, lead to sustained suppression of cerebral arteriolar responses to N-methyl-D-aspartate (NMDA). However, whether arteriolar dilator responses to NMDA are reduced during arterial hypoxia has nev...

journal_title：Brain research

authors： Bari F,Thore CR,Louis TM,Busija DW

更新日期：1998-01-12 00:00:00

abstract：:The importance of particular genes in neuronal death following global cerebral ischemia can readily be studied in genetically modified mice provided a reliable model of ischemia is available. For that purpose, we developed a mouse model of global cerebral ischemia that induces consistent damage to different regions of...

journal_title：Brain research

authors： Olsson T,Wieloch T,Smith ML

更新日期：2003-08-29 00:00:00

abstract：:Opioids elicit antinociception in mammals through three distinct types of receptors designated as mu, kappa and delta. However, it is not clear what type of opioid receptor mediates antinociception in non-mammalian vertebrates. Radioligand binding techniques were employed to characterize the site(s) of opioid action i...

journal_title：Brain research

authors： Newman LC,Wallace DR,Stevens CW

更新日期：2000-11-24 00:00:00

abstract：:To examine the effect of development on rabbit brain insulin and insulin-like growth factor (IGF) receptor expression, we characterized and quantitated receptor mRNAs by Northern blot analysis and affinity-labeled ligand bound receptors by SDS-PAGE and autoradiography. At various stages of development ranging from 23 ...

journal_title：Brain research

authors： Devaskar SU,Sadiq HF,Holtzclaw L,George M

更新日期：1993-03-05 00:00:00

abstract：:Endogenous hyperprolactinaemia was induced in intact male rats by transplantation of pituitaries under the kidney capsule. Five days later the utilization of noradrenaline (NA) and dopamine (DA) in individual brain nuclei and changes of plasma prolaction (PRL) were measured. Inhibition of catecholamine synthesis by al...

journal_title：Brain research

authors： Kovács GL,Drago F,Acsai L,Tihanyi A,Scapagnini U,Telegdy G

更新日期：1984-12-17 00:00:00

abstract：:Peripheral input to lamina VIII interneurones was investigated by using extracellular and/or intracellular records from them. The interneurones were located in the L4-L5 spinal segments and projected to contralateral motor nuclei in the L7 segment. They constituted a non-homogeneous population but their input from mus...

journal_title：Brain research

authors： Jankowska E,Noga BR

更新日期：1990-12-10 00:00:00