Differential expression of the muscarinic m2 acetylcholine receptor by small and large motoneurons of the rat spinal cord.

abstract：:Oxidative stress has been suggested to play a key role in the neuropathogenesis of HIV infection. HIV proteins (gp120, Tat) and proinflammatory cytokines can trigger the production of reactive oxygen species (ROS), resulting in DNA and RNA lesions. Among all the lesions induced by ROS, one of the most abundant lesions...

journal_title：Brain research

authors： Zhang Y,Wang M,Li H,Zhang H,Shi Y,Wei F,Liu D,Liu K,Chen D

更新日期：2012-06-06 00:00:00

abstract：:The behavioral and physiological effects of electrical stimulation of the nucleus locus coeruleus (LC) were studied in the awake rat. LC electrodes consistently supported high rates of self-stimulation (SS). LC stimulation also inhibited spontaneous cellular discharges in the hippocampus (HPC). Both the LC-induced inh...

journal_title：Brain research

authors： Segal M,Bloom FE

更新日期：1976-05-14 00:00:00

abstract：:The effects of GM1 ganglioside (30 mg/kg i.p.) administration for 22 days on choline acetyltransferase (ChAT) activity and noradrenaline (NA) levels in the cerebral cortex and on the acquisition of active and passive avoidance-conditioned responses were investigated in both sham-operated rats and in rats with a unilat...

journal_title：Brain research

authors： Casamenti F,Bracco L,Bartolini L,Pepeu G

更新日期：1985-07-08 00:00:00

abstract：:The involvement of striatal cholinergic neurons in the release of dopamine (DA) elicited by the mu-opioid receptor agonist DAGO ([D-Ala2, NMePhe4-Gly5(ol)]enkephalin) was explored. The striatal release of DA was measured by microdialysis in rats anesthetized with chloral hydrate. When infused in the striatum, through ...

journal_title：Brain research

authors： Dourmap N,Clero E,Costentin J

更新日期：1997-02-28 00:00:00

abstract：:The responses of spinocervical neurons to sinusoidal hair displacements were studied during and in the absence of radiant heating of parts of the hindpaw to noxious levels (45-65 degrees C). Noxious heat usually increased background discharge and lowered the signal-to-noise ratio at low frequencies of hair displacemen...

journal_title：Brain research

authors： King GW,Ebner TJ,Bloedel JR

更新日期：1981-10-05 00:00:00

abstract：:Our recent researches have identified increased expression of miR-21-5p in rats brain following traumatic brain injury (TBI), which protected against blood-brain barrier (BBB) damage. To further study the mechanism underlying the role of miR-21-5p on alleviating BBB damage after TBI, we performed the scratch injury mo...

journal_title：Brain research

authors： Ge X,Huang S,Gao H,Han Z,Chen F,Zhang S,Wang Z,Kang C,Jiang R,Yue S,Lei P,Zhang J

更新日期：2016-11-01 00:00:00

abstract：:Opioid-binding cell adhesion molecule (OBCAM) is the member of the IgLON family, a subgroup of the immunoglobulin superfamily. In the present study, the functions and dynamics of OBCAM were investigated in hippocampal neurons in vitro. Western blotting revealed that OBCAM expression was low at early stages of culture ...

journal_title：Brain research

authors： Yamada M,Hashimoto T,Hayashi N,Higuchi M,Murakami A,Nakashima T,Maekawa S,Miyata S

更新日期：2007-08-24 00:00:00

abstract：:Several studies have reported transient expression of tyrosine hydroxylase in a subpopulation of neurons in the bed nucleus of stria terminalis of preadolescent rats. The tyrosine hydroxylase immunoreactive (TH) neurons, which are of small to medium size and often display a typical bipolar configuration, are confined ...

journal_title：Brain research

authors： Beltramino CA,Forbes MS,Swanson DJ,Alheid GF,Heimer L

更新日期：1996-01-08 00:00:00

abstract：:Human soleus H reflexes are attenuated during passive pedalling movements. This depression occurs within 70 ms of movement onset. We hypothesized that the reflex gain would return to control values with a similar brevity following movement. However, H reflexes sampled following a slow (10 rpm) passive pedalling moveme...

journal_title：Brain research

authors： Misiaszek JE,Brooke JD,Lafferty KB,Cheng J,Staines WR

更新日期：1995-04-17 00:00:00

abstract：:Increased neurogenesis by promoting proliferation of neural precursor cells in the adult dentate gyrus might be beneficial for the treatment of psychiatric disorders. Results demonstrate that bFGF is necessary for the proliferation of neural precursor cells and that the glycogen synthase kinase-3β (GSK-3β) and β-caten...

journal_title：Brain research

authors： Boku S,Nakagawa S,Toda H,Kato A,Takamura N,Omiya Y,Inoue T,Koyama T

更新日期：2013-01-25 00:00:00

abstract：:The pedunculopontine nucleus (PPN), the cholinergic arm of the reticular activating system (RAS), is known to modulate waking and rapid eye movement (REM) sleep. REM sleep decreases between 10 and 30 days postnatally in the rat, with the majority occurring between 12 and 21 days. We investigated the possibility that c...

journal_title：Brain research

authors： Good CH,Bay KD,Buchanan R,Skinner RD,Garcia-Rill E

更新日期：2007-01-19 00:00:00

abstract：:Frontal and temporal sections of 4 normal human brains and 3 brains from patients with a diagnosis of Alzheimer-type dementia (ATD) were stained with Vicia villosa lectin conjugated to biotin to localize glycoproteins containing terminal N-acetylgalactosamine. These lectin binding sites were localized at the surface o...

journal_title：Brain research

authors： Kobayashi K,Emson PC,Mountjoy CQ

更新日期：1989-09-25 00:00:00

abstract：:Acute, progressive global brain ischemia was induced in awake or anesthetized rats for 5-75 min. Ischemia was achieved with a subclavian-carotid artery occlusion technique (SCOT). After thoracotomy, both subclavian arteries (proximal to their vertebral branches) were tied-off and carotid artery catheter-snares install...

journal_title：Brain research

authors： de la Torre JC,Saunders J,Fortin T,Butler K,Richard M

更新日期：1991-02-22 00:00:00

abstract：:Regulation of the intracellular calcium concentration ([Ca(2+)](i)) is of critical importance for synaptic function. Therefore, neurons buffer [Ca(2+)](i) using intracellular Ca(2+)-binding proteins (CaBPs). Previous evidence suggests that Calbindin-D(28K) (CB), an abundantly expressed endogenous fast CaBP, plays an i...

journal_title：Brain research

authors： Westerink RH,Beekwilder JP,Wadman WJ

更新日期：2012-04-23 00:00:00

abstract：:Beta-amyloid peptide (Aβ) has a causal role in the pathophysiology of Alzheimer's disease (AD). Recent studies indicate that Aβ can disrupt excitatory glutamatergic synaptic function at synaptic level. However, the underlying mechanisms remain obscure. In this study, we recorded evoked and spontaneous EPSCs in hippoca...

journal_title：Brain research

authors： Yao W,Zou HJ,Sun D,Ren SQ

更新日期：2013-06-17 00:00:00

abstract：:Microinjection of bicuculline (Bic) into the unilateral putamen (Put) of the cat resulted in periodic occurrence of contralateral movement of the head (dystonia). Corresponding to this dystonic movement, repetitive spikes of the field potential occurring in the Put of the injected side and strong inhibition of the ext...

journal_title：Brain research

authors： Yamada H,Fujimoto K,Yoshida M

更新日期：1995-04-24 00:00:00

abstract：:A 'new' and orderly representation of the body surface was found in the cerebral cortex of the cat. This somatotopic map was located in the anterior ectosylvian sulcus (AES), an area known to represent several modalities, but believed to be distinguished from primary sensory cortex by its lack of sensory topographies....

journal_title：Brain research

authors： Clemo HR,Stein BE

更新日期：1982-03-04 00:00:00

abstract：:Milk ejection-related bursts of action potentials recurred at fairly regular intervals during suckling in oxytocin cells of anesthetized lactating rats. Additional milk ejection-related bursts were frequently induced in response to vaginal distension. The latency for the induced response was 2.9 +/- 0.2 s and the size...

journal_title：Brain research

authors： Negoro H,Uchide K,Tadokoro Y,Honda K,Higuchi T

更新日期：1987-02-24 00:00:00

abstract：:Experiments were carried out in rats to (1) elaborate upon the sepcificity of drug action in the periaqueductal gray matter (PAG), and (2) to evaluate the posible congruence of PAG sites of morphine-induced and stimulation-produced analgesis (SPA) applied at virtually identical PAG loci. It was demonstrated that the e...

journal_title：Brain research

authors： Lewis VA,Gebhart GF

更新日期：1977-03-25 00:00:00

abstract：:To achieve a better understanding of the parallel information processing that takes place in the nervous system, many researchers have recently begun to use multielectrode techniques to obtain high spatial- and temporal-resolution recordings of the firing patterns of neural ensembles. Apart from the complexities of ac...

journal_title：Brain research

authors： Fernández E,Ferrandez J,Ammermüller J,Normann RA

更新日期：2000-12-22 00:00:00

abstract：:The distribution of calretinin containing neurons examined by in situ hybridization mapping was compared with that obtained by immunocytochemistry in the brain of octopus. Results revealed a close correspondence between the two types of investigations. Western blot analysis disclosed a 29 kDa protein immunostained wit...

journal_title：Brain research

authors： Altobelli GG,Cimini V

更新日期：2007-02-09 00:00:00

abstract：:The extraction and utilization of sound level changes in acoustic-autonomic reflex systems were studied on a vasoconstriction response in the tail of nonanesthetized rats. The vasoconstriction was found to depend on sound level and changes of level in the following ways. (a) It increased as a linear function of sound ...

journal_title：Brain research

authors： Borg E

更新日期：1980-04-21 00:00:00

abstract：:Bilateral intranigral administration of the selective NK-1 tachykinin receptor agonist [AcArg6, Sar9, Met(O2)11]SP6-11 (0-1 nmol total bilateral dose) selectively induced grooming in rats. This response was blocked by concurrent intranigral administration of the NK-1 tachykinin receptor antagonist RP 67580 (2 nmol), b...

journal_title：Brain research

authors： Stoessl AJ,Brackstone M,Rajakumar N,Gibson CJ

更新日期：1995-11-27 00:00:00

abstract：:The existence of monosynaptic contacts between primary afferents and motoneurons in the lumbar spinal cord of the turtle Pseudemys scripta elegans was demonstrated by intracellular injections of horseradish peroxidase. Three afferent-motoneuron combinations were satisfactorily labeled and revealed 1, 4 and 6 contacts ...

journal_title：Brain research

authors： Ruigrok TJ,Crowe A,ten Donkelaar HJ

更新日期：1985-07-22 00:00:00

abstract：:Brain cortico-striatal circuits have consistently been implicated in the pathology of addiction related disorders. We applied a reliable seed-based analysis of the resting-state brain activity to comprehensively delineate the subdivisions of striatal functional connectivity implicated in internet gaming disorder. Amon...

journal_title：Brain research

authors： Hong SB,Harrison BJ,Dandash O,Choi EJ,Kim SC,Kim HH,Shim DH,Kim CD,Kim JW,Yi SH

更新日期：2015-03-30 00:00:00

abstract：:Cerebral cortical blood flow (CBF) was measured autoradiographically in conscious mice without the monoamine oxidase B (MAOB) gene (KO, n=11) and the corresponding wild-type animals (WILD, n=11). Subgroups of animals of each genotype received a continuous intravenous infusion over 30 min of phenylethylamine (PEA), an ...

journal_title：Brain research

authors： Scremin OU,Holschneider DP,Chen K,Li MG,Shih JC

更新日期：1999-04-03 00:00:00

abstract：:In a previous study, male rats showed behavioural deficits after a single restraint stress but not after 5 daily restraint periods (i.e. adaptation had developed): female rats although less affected by single restraint failed to adapt over the same time course. This sex difference was associated with the male but not ...

journal_title：Brain research

authors： Haleem DJ,Kennett G,Curzon G

更新日期：1988-08-23 00:00:00

abstract：:In the course of studies on the responsiveness of mediobasal hypothalamic neurons to the iontophoretic application of cortisol, it was found that positive currents applied to a sodium chloride (1 M) barrel alone, but not to a choline chloride (1 M) barrel, frequently increased the firing of these neurons. Subsequently...

journal_title：Brain research

authors： Mandelbrod I,Feldman S,Werman R

更新日期：1983-08-22 00:00:00

abstract：:The interpeduncular nucleus (IPN) was stimulated electrically while single-cell activity was recorded in the nucleus raphe magnus (NRM) of rats under pentobarbital anesthesia. Two classes of NRM cell were examined, those inhibited (off-cells) and those excited (on-cells) by noxious mechanical skin stimulation. Off-cel...

journal_title：Brain research

authors： Hentall ID,Budhrani VM

更新日期：1990-07-09 00:00:00

abstract：:Abeta amyloidosis and tauopathy are characteristic changes in the brain of Alzheimer's disease. Although much evidence suggests that Abeta deposit is a critical initiation factor, the pathological pathway between Abeta amyloidosis and tau accumulation remains unclear. Tau accumulation was examined in the doubly transg...

journal_title：Brain research

authors： Samura E,Shoji M,Kawarabayashi T,Sasaki A,Matsubara E,Murakami T,Wuhua X,Tamura S,Ikeda M,Ishiguro K,Saido TC,Westaway D,St George Hyslop P,Harigaya Y,Abe K

更新日期：2006-06-13 00:00:00