The interpeduncular nucleus excites the on-cells and inhibits the off-cells of the nucleus raphe magnus.

Abstract:

:The interpeduncular nucleus (IPN) was stimulated electrically while single-cell activity was recorded in the nucleus raphe magnus (NRM) of rats under pentobarbital anesthesia. Two classes of NRM cell were examined, those inhibited (off-cells) and those excited (on-cells) by noxious mechanical skin stimulation. Off-cells (92%) were found to be inhibited by IPN stimulation, whereas on-cells (50%) were excited. Based on previously suggested roles for the NRM neurons, we argue that both effects are hyperalgetic.

journal_name

Brain Res

journal_title

Brain research

authors

Hentall ID,Budhrani VM

doi

10.1016/0006-8993(90)91476-w

subject

Has Abstract

pub_date

1990-07-09 00:00:00

pages

322-4

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(90)91476-W

journal_volume

522

pub_type

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