Involvement of cholinergic neurons in the release of dopamine elicited by stimulation of mu-opioid receptors in striatum.

abstract：:Adult Wistar rats injected with the dopamine receptor agonist apomorphine display different types of motility patterns with respect to oral stereotypes and locomotor activities. It was tested whether phenotypes exhibiting either 'sniffing' or 'non-sniffing' behaviour differed in gene structures of dopamine receptors D...

journal_title：Brain research

authors： Germeyer S,Birke A,Schmitt U,Dahmen N,Hiemke C,Havemann-Reinecke U

更新日期：2002-02-01 00:00:00

abstract：:The response of the endoneurial vasculature in rat sciatic nerve following crush injury was investigated by morphometric analysis of serial nerve transverse sections at the site of injury and in distal segments at 1, 2, 3, 6, and 9 weeks after injury. Quantitative analysis included determination of the number of vesse...

journal_title：Brain research

authors： Podhajsky RJ,Myers RR

更新日期：1993-09-24 00:00:00

abstract：:The developmental and age-related changes of the dopamine transporter (DAT), and the dopamine D1 and D2 receptor (D1R and D2R) subtypes were investigated in basal ganglia (BG) of human brain. DAT immunostaining was mainly observed in the neuropil, neurons, and glia of the striatum. The DAT-positive neuropil was detect...

journal_title：Brain research

authors： Meng SZ,Ozawa Y,Itoh M,Takashima S

更新日期：1999-10-02 00:00:00

abstract：:Traumatic brain injury (TBI) affects 2.8 million people annually in the United States, with significant populations suffering from ongoing cognitive dysfunction. Impairments in decision-making can have major implications for patients and their caregivers, often enduring for years to decades, yet are rarely explored in...

journal_title：Brain research

authors： Shaver TK,Ozga JE,Zhu B,Anderson KG,Martens KM,Vonder Haar C

更新日期：2019-02-01 00:00:00

abstract：:Preconditioning describes a variety of treatments that induce neurons to become more resistant to a subsequent ischemic insult. How preconditioned neurons adapt to subsequent ischemic stress is not fully understood, but is likely to involve multiple protective mechanisms. We hypothesized hypoxic preconditioning induce...

journal_title：Brain research

authors： Arthur PG,Lim SC,Meloni BP,Munns SE,Chan A,Knuckey NW

更新日期：2004-08-13 00:00:00

abstract：:Glycogen synthase kinase (GSK)-3beta and extracellular signal-regulated kinase (ERK) regulate several cellular signaling pathways in common, including embryonic development, cell differentiation and apoptosis. In this study, we investigated whether GSK-3beta inhibition is involved in ERK activation, which affects the ...

journal_title：Brain research

authors： Kim SD,Yang SI,Kim HC,Shin CY,Ko KH

更新日期：2007-12-01 00:00:00

abstract：:This study shows that in the choroid plexus of Rana esculenta particulate guanylate cyclase (GC) is appreciably stimulated by porcine brain natriuretic peptide (BNP). Ultracytochemical tests for GC show that BNP notably increases the enzymatic reaction product along the apical surfaces of the epithelial cells. It can ...

journal_title：Brain research

authors： Vagnetti D,Tei S,Secca T,Santarella B,Roscani C,Farnesi RM

更新日期：1995-12-24 00:00:00

abstract：:Social defeat is a powerful experience that often leads to drastic physiological and behavioral changes in many animal species. An example of such a change is conditioned defeat in Syrian hamsters. The neurophysiological mechanisms that underlie such changes are not yet fully understood, however, there is evidence tha...

journal_title：Brain research

authors： Jasnow AM,Huhman KL

更新日期：2001-11-30 00:00:00

abstract：:Activity produced by direct microelectrophoretic application of glutamate onto 19 convergent neurones in trigeminal nucleus caudalis, was strongly depressed during and after the application of heterotopic noxious conditioning stimuli: noxious heat (52 degrees C) applied to the tail, noxious pinches applied to the tail...

journal_title：Brain research

authors： Villanueva L,Cadden SW,Le Bars D

更新日期：1984-10-29 00:00:00

abstract：:The actions of pentobarbital (PB) and diphenylhydantoin (DPH) have been studied on neurons of dorsal root ganglia from adult rats. At anesthetic level (i.e. 1--2 x 10(-4) M), PB greatly enhanced neuronal responses to gamma-aminobutyric acid (GABA); at 10(-3) M PB caused a small depolarization and profoundly attenuated...

journal_title：Brain research

authors： Connors BW

更新日期：1981-03-02 00:00:00

abstract：:The regenerating optic nerve of goldfish first reestablishes a rough retinotopic map on the tectum, then goes through an activity dependent refinement that appears to involve the elimination of inappropriate branches from early regenerated arbors. Retinotopically appropriate branches and synapses may be stabilized bec...

journal_title：Brain research

authors： Schmidt JT,Shashoua VE

更新日期：1988-04-19 00:00:00

abstract：:Near-infrared spectroscopy (NIRS) enables noninvasive measurement of concentration changes of oxy- and deoxy-hemoglobin. The present study investigated cerebral representations of motion illusion by NIRS and examined several experimental procedures to determine an efficient procedure that can shorten the experimental ...

journal_title：Brain research

authors： Hashimoto T,Minagawa-Kawai Y,Kojima S

更新日期：2006-03-10 00:00:00

abstract：:Emerging evidence that autophagy serves as a sweeper for toxic materials in the brain gives us new insight into the pathophysiology of neurodegenerative diseases. Autophagy is important for maintaining cellular homeostasis associated with metabolism. Some neurodegenerative diseases such as Alzheimer׳s and Parkinson׳s ...

journal_title：Brain research

authors： Lim Y,Cho H,Kim EK

更新日期：2016-10-15 00:00:00

abstract：:When rabbit retinas are exposed in vitro to specific excitatory amino acid receptor agonists certain GABAergic amacrine cells are activated to cause a release of GABA. The GABA that is not released can be detected by immunohistochemistry. Exposure of tissues to kainate or NMDA each caused a characteristic change in th...

journal_title：Brain research

authors： Osborne NN,Pergande G,Block F,Schwarz M

更新日期：1994-12-26 00:00:00

abstract：:The locus coeruleus of the adult albino rat is a clearly delimited nucleus in Nissl-stained preparations. It is surrounded by an extensive, relatively neuron-free neuropil which is not stained in reduced silver and Luxol fast blue preparations. Most if not all locus coeruleus neurons contain the enzyme dopamine-beta-h...

journal_title：Brain research

authors： Swanson LW

更新日期：1976-06-25 00:00:00

abstract：:The distribution of calretinin containing neurons examined by in situ hybridization mapping was compared with that obtained by immunocytochemistry in the brain of octopus. Results revealed a close correspondence between the two types of investigations. Western blot analysis disclosed a 29 kDa protein immunostained wit...

journal_title：Brain research

authors： Altobelli GG,Cimini V

更新日期：2007-02-09 00:00:00

abstract：:In the present experiment we examined the effect of progesterone upon dopamine (DA) release induced by a direct infusion of unlabeled L-dihydroxyphenylalanine (L-DOPA) into the caudate nucleus of freely behaving rats. Ovariectomized rats were implanted with a push-pull cannula directed at the caudate nucleus and subje...

journal_title：Brain research

authors： Dluzen DE,Ramirez VD

更新日期：1989-08-07 00:00:00

abstract：:Changes in GABA(A) receptor alpha(1) subunit gene expression occur in the globus pallidus and substantia nigra pars reticulata following lesions of the nigrostriatal tract. To determine whether these changes are translated at the protein level, we performed quantitative autoradiography with the alpha(1) selective liga...

journal_title：Brain research

authors： Chadha A,Howell O,Atack JR,Sur C,Duty S

更新日期：2000-04-17 00:00:00

abstract：:Patches of transnueronal degeneration were produced in the lateral geniculate nucleus (LGN) by retinal laser burns and a tarsorrhaphy was performed in the contralateral eye of Macaca mulatta during infancy. The adverse effect of unilateral visual deprivation on geniculate cell growth was absent in those portions of de...

journal_title：Brain research

authors： Von Noorden GK,Crawford ML,Middle-Ditch PR

更新日期：1976-07-30 00:00:00

abstract：:Postnatal development of the K+-stimulated release of [3H]GABA in rat cortex slices was compared to the density of Gray type 2 synapses (which correlate with GABAergic synapses in rat cortex). The [3H]GABA release system develops earlier than the inhibitory synapses which suggests that, at least in the young cortical ...

journal_title：Brain research

authors： Balcar VJ,Dammasch I,Wolff JR

更新日期：1983-11-01 00:00:00

abstract：:A total of 183 nucleus basalis of Meynert (NBM) neurons were recorded in a monkey performing a delayed response task. Significant changes in discharge rate were detected in 74% of the NBM cells sampled with most responses occurring in the choice (64%) or the reward (67%) epochs of the task. Neuronal responses in the c...

journal_title：Brain research

authors： Richardson RT,DeLong MR

更新日期：1986-12-10 00:00:00

abstract：:This study was performed to understand the anatomical substrates of hypothalamic modulation of jaw movements. After cholera toxin B subunit (CTb) injection into the parvicellular reticular formation (RFp) of the rat medulla oblongata, where many trigeminal premotor neurons have been known to exist, numerous CTb-labele...

journal_title：Brain research

authors： Notsu K,Tsumori T,Yokota S,Sekine J,Yasui Y

更新日期：2008-12-09 00:00:00

abstract：:Mesenchymal stem cell (MSC) transplantation has been reported to improve neurologic function after ischemic injury. However, the detailed mechanisms by which MSCs promote functional recovery are not fully understood. Interleukin-10 (IL-10) is a well-known anti-inflammatory cytokine with neuroprotective effects with re...

journal_title：Brain research

authors： Li J,Zhu H,Liu Y,Li Q,Lu S,Feng M,Xu Y,Huang L,Ma C,An Y,Zhao RC,Wang R,Qin C

更新日期：2010-06-02 00:00:00

abstract：:Spontaneous alternation which is disrupted by lesion of septal dopaminergic (DA) afferents was chosen as a behavioral marker for the study of functional interactions between DA and noradrenergic (NA) innervation of the lateral septum. Three groups of rats were studied: a solvent group which received only vehicle injec...

journal_title：Brain research

authors： Taghzouti K,Le Moal M,Simon H

更新日期：1991-06-21 00:00:00

abstract：:Myelin is probably one of the most fascinating and innovative biological acquisition: a glia plasma membrane tightly wrapped around an axon and insulating it. Chondrichthyans (cartilaginous fishes) form a large group of vertebrates, and they are among oldest extant jawed vertebrate lineage. It has been known from stud...

journal_title：Brain research

authors： de Bellard ME

更新日期：2016-06-15 00:00:00

abstract：:The ability of beta-phenylethylamine (PEA) to reverse (1) chlorpromazine-induced activation of striatal tyrosine hydroxylase, and (2) catalepsy produced by chlorpromazine, was examined. PEA, in a dose of 75 mg/kg, caused approximately 50% reduction in the degree of tyrosine hydroxylase stimulation produced by 20 mg/kg...

journal_title：Brain research

authors： Stoff DM,Gale K

更新日期：1981-05-04 00:00:00

abstract：:The brainstem nucleus, locus coeruleus (LC), is the major, if not the sole, source of noradrenergic (NE) innervation of the telencephalon. It is generally held that LC neurons project diffusely to the entire neuroaxis and this had been the basis for theories that postulate 'general' functions (sleep, attention, learni...

journal_title：Brain research

authors： Shipley MT,Halloran FJ,de la Torre J

更新日期：1985-03-11 00:00:00

abstract：:Local formation of oestrogens from androgens by aromatase cytochrome P-450 within brain cells is crucial for the sexual differentiation of the mammalian CNS. Aromatase activity has been detected in several brain regions of the developing rodent brain. In the present study, we used a mouse-specific, peptide-generated, ...

journal_title：Brain research

authors： Beyer C,Green SJ,Barker PJ,Huskisson NS,Hutchison JB

更新日期：1994-02-28 00:00:00

abstract：:Cytosol androgen receptors were assayed in guinea pig brain and pituitary tissues, using [3H]R1881 as ligand. These receptors had an apparent Kd of 0.04 nM and were androgen-specific (R1881 greater than dihydrotestosterone greater than testosterone = estradiol greater than progesterone). Concentrations of cytosol andr...

journal_title：Brain research

authors： Bonneau M,Ahdieh HB,Thornton JE,Feder HH

更新日期：1987-06-09 00:00:00

abstract：:Pathophysiological responses to peripheral nerve injury include alterations in the activity, intrinsic membrane properties and excitability of spinal neurons. The intrinsic excitability of α-motoneurons is controlled in part by the expression, regulation, and distribution of membrane-bound ion channels. Ion channels, ...

journal_title：Brain research

authors： Romer SH,Dominguez KM,Gelpi MW,Deardorff AS,Tracy RC,Fyffe RE

更新日期：2014-02-14 00:00:00