beta-Phenylethylamine reversal of chlorpromazine-induced activation of striatal tyrosine hydroxylase and catalepsy.

abstract：:An in vitro method was developed to separately visualize dopaminergic, noradrenergic and serotoninergic terminals in the cerebral, hippocampal and cerebellar cortices of the rat, by means of the glyoxylic histochemical fluorescence method. Animals were pretreated with alpha-methylparatyrosine to deplete catecholamine ...

journal_title：Brain research

authors： Berger B,Glowinski J

更新日期：1978-05-19 00:00:00

abstract：:Glutamate kills sensitive neurons through several steps downstream to receptor activation: increased free Ca2+ levels, activation of various enzymes and accumulation of reactive oxygen species (ROS). We have evaluated in a well established model of neuronal cultures the neuroprotective effects of blocking these mechan...

journal_title：Brain research

authors： Ciani E,Grøneng L,Voltattorni M,Rolseth V,Contestabile A,Paulsen RE

更新日期：1996-07-22 00:00:00

abstract：:Many neurons release a variety of amino acids in response to depolarizing stimuli. Although some of these amino acids, namely, glutamate, aspartate, and gamma-aminobutyric acid (GABA), have been qualified as neurotransmitters, functional roles of the other amino acids including alanine remain obscure. We investigated ...

journal_title：Brain research

authors： Koga T,Kozaki S,Takahashi M

更新日期：2002-10-18 00:00:00

abstract：:Converging evidence suggests that compromised motor abilities in hemiparetic cerebral palsy are not solely due to impairments in motor execution, but are also related to deficits in action planning. The present study had two aims. First, we compared grip planning in a sequential task between participants with left-sid...

journal_title：Brain research

authors： Crajé C,van der Kamp J,Steenbergen B

更新日期：2009-03-19 00:00:00

abstract：:After-effects of fusimotor action on dynamic sensitivity of spindle primary afferents from soleus resulted from low rate stimulation of both static and dynamic gamma-axons. Sensitivity to small sinusoidal stretches superimposed on triangles was enhanced during triangular lengthening but not during shortening. These af...

journal_title：Brain research

authors： Baumann TK,Emonet-Dénand F,Hulliger M

更新日期：1982-01-28 00:00:00

abstract：:Several labeled neurotransmitter substances or precursors ( [3H]histamine, [3H]serotonin, and [3H]choline) were injected with pressure into the cell body of C2, an identified putative histaminergic neuron in the cerebral ganglion of Aplysia in order to study the selectivity of axonal transport. We examined transport o...

journal_title：Brain research

authors： Gotoh H,Schwartz JH

更新日期：1982-06-17 00:00:00

abstract：:Visual spatial orienting of attention towards exogenous cues has been one of the attentional functions considered to be spared in ADHD. Here we present a design in which 60 (30 ADHD) children, age: 10.9±1.4, were asked to covertly orient their attention to one or two (out of four) cued locations, and search for a targ...

journal_title：Brain research

authors： Ortega R,López V,Carrasco X,Anllo-Vento L,Aboitiz F

更新日期：2013-02-01 00:00:00

abstract：:A site-specific antibody against the principal gap junctional protein in heart (connexin 43) was used to determine immunohistochemically the cellular localization of this protein in rat brain. Structures labelled with the antibody included gap junctional membranes between glial, ependymal, pial and arachnoid cells as ...

journal_title：Brain research

authors： Yamamoto T,Ochalski A,Hertzberg EL,Nagy JI

更新日期：1990-02-05 00:00:00

abstract：:Glioblastoma is the most aggressive form of gliomas and is associated with short survival. Recent advancements in molecular genetics resulted in the identification of glioma genomic, epigenomic and transcriptomic hallmarks, and multidimensional data allowed clustering of glioblastomas into molecular subtypes. Parallel...

journal_title：Brain research

authors： Nagy A,Eder K,Selak MA,Kalman B

更新日期：2015-01-21 00:00:00

abstract：:The dentate gyrus is believed to play an important pathophysiological role during experimentally induced kindling. In this study, we investigated whether an altered content of the calcium binding protein calbindin-D(28k) or an increased intrinsic excitability of hippocampal granule cells contribute to the induction of...

journal_title：Brain research

authors： Dietrich D,Podlogar M,Ortmanns G,Clusmann H,Kral T

更新日期：2005-01-25 00:00:00

abstract：:Parkinson's disease (PD) is a common neurodegenerative disease characterized by progressive loss of midbrain dopaminergic neurons. To gain an insight into the mechanisms underlying the progression of PD, gene expression analysis was performed using two different brain regions, the substantia nigra pars compacta (SN) a...

journal_title：Brain research

authors： Ohnuki T,Nakamura A,Okuyama S,Nakamura S

更新日期：2010-07-30 00:00:00

abstract：:The diurnal rhythm of neuropeptide Y (NPY)-like immunoreactivity was examined in 9 discrete hypothalamic sites of rats maintained on a 12:12 h light/dark cycle. Significant bimodal rhythms of NPY concentration were detected in the suprachiasmatic and arcuate nuclei, with significant peaks just prior to onset of the no...

journal_title：Brain research

authors： Jhanwar-Uniyal M,Beck B,Burlet C,Leibowitz SF

更新日期：1990-12-17 00:00:00

abstract：:Pathophysiological responses to peripheral nerve injury include alterations in the activity, intrinsic membrane properties and excitability of spinal neurons. The intrinsic excitability of α-motoneurons is controlled in part by the expression, regulation, and distribution of membrane-bound ion channels. Ion channels, ...

journal_title：Brain research

authors： Romer SH,Dominguez KM,Gelpi MW,Deardorff AS,Tracy RC,Fyffe RE

更新日期：2014-02-14 00:00:00

abstract：:In urodele amphibians, the hypothalamic neuropeptide arginine vasotocin and the adrenal steroid corticosterone interact to regulate reproductive behavior by actions in the brain. The present study investigated signal transduction pathways underlying acute effects of vasotocin and corticosterone, presumably mediated vi...

journal_title：Brain research

authors： Gasser PJ,Orchinik M

更新日期：2007-02-23 00:00:00

abstract：:In anaesthetized cats, effects of iontophoretic application of angiotensin II were studied in the nuclei of the tractus solitarius. Specifically, its effects were tested on single respiratory neurones, having rhythmic activity related temporally with the phrenic nerve discharge, and on presumed reflex interneurones, w...

journal_title：Brain research

authors： Sessle BJ,Henry JL

更新日期：1987-03-24 00:00:00

abstract：:Choline acetyltransferase (ChAT) and glutamic acid decarboxylase (GAD) activities were measured in various visual structures of the pigeon brain after long-term monocular deprivation followed by short-term binocular presence or absence of light stimulation. The short-term phase (45 min) was coupled with a 2-deoxygluco...

journal_title：Brain research

authors： Bagnoli P,Burkhalter A,Vischer A,Henke H,Cuénod M

更新日期：1982-09-16 00:00:00

abstract：:We have previously used organotypic cultures to study mechanisms regulating phenotypic expression of neurotransmitter characters in the brain. Our previous work indicated that nerve growth factor (NGF) specifically increased the activity of choline acetyltransferase (CAT) in striatal cholinergic interneurons. In the p...

journal_title：Brain research

authors： Martínez HJ,Dreyfus CF,Jonakait GM,Black IB

更新日期：1987-06-02 00:00:00

abstract：:The present study was designed to test the hypothesis that a major excitatory mechanism for the expression of feline defensive rage behavior involves the medial nucleus of the amygdala which utilizes substance P as a neurotransmitter in a direct output pathway that supplies the medial hypothalamus. In phase I of the e...

journal_title：Brain research

authors： Shaikh MB,Steinberg A,Siegel A

更新日期：1993-10-22 00:00:00

abstract：:The distribution and subcellular localization of AH9 antigen, recognized by a monoclonal antibody AH9, were examined in rat brain. Highest expression was observed in the lamina lucidum of the dentate gyrus of the rat hippocampus. Synaptic subfields of other limbic areas also expressed AH9 antigen at a substantial leve...

journal_title：Brain research

authors： Fukuyama R,Rapoport SI

更新日期：1996-05-06 00:00:00

abstract：:Following electrophysiological techniques we investigated whether wallerian degeneration of the cat sural nerve may be influenced by (1) its peripheral connection and (2) the distance from the cell body. Distal stumps connected to their innervation sites peripherally showed less degeneration than proximal ones when is...

journal_title：Brain research

authors： Delgado-Lezama R,Muñoz-Martínez EJ

更新日期：1990-08-13 00:00:00

abstract：:Recent studies suggest that apolipoprotein E (apoE) might play a neurotrophic function in the central nervous system and that altered functioning of this molecule could result in neurodegeneration. The main objective of this study was to determine if neurodegenerative and cognitive alterations in apoE-deficient mice a...

journal_title：Brain research

authors： Masliah E,Samuel W,Veinbergs I,Mallory M,Mante M,Saitoh T

更新日期：1997-03-21 00:00:00

abstract：:Intracellular Ca2+ concentration ([Ca2+]i) was measured in neurons, acutely dissociated from the rat dorsal raphe nucleus (DRN), with the fluorescent calcium probe Fluo3. Nociceptin (300 nM) had no effect on resting [Ca2+]i but reduced the magnitude of the [Ca2+]i transient triggered by depolarization in 90% of neuron...

journal_title：Brain research

authors： Roumy M,Zajac J

更新日期：1999-10-23 00:00:00

abstract：:Neonatal rat superior cervical ganglia were mechanically dissociated, and the sympathetic neurons grown in dispersed cell cultures. Intracellular microelectrodes were used to study the effects of tetraethylammonium (TEA+), a blocker of outward K+ currents, on the excitable properties of these neurons. Addition of TEA+...

journal_title：Brain research

authors： Suppes T

更新日期：1984-02-20 00:00:00

abstract：:Extended incubation of hippocampus slices in the presence of fatty acid-free bovine serum albumin (FAF-BSA) strongly enhanced the release of D-[3H]aspartate and [14C]GABA induced by veratridine. Saturation of the FAF-BSA with oleic acid abolished the enhancing effect. Spontaneous release and K+-induced release were no...

journal_title：Brain research

authors： Minc-Golomb D,Eimerl S,Levy Y,Schramm M

更新日期：1988-08-09 00:00:00

abstract：:Endogenous long-duration burst-organizing potentials (driver potentials, DPs) generated by neurons in the lobster cardiac ganglion play a critical role in the ability of the system to generate rhythmic bursts of nerve impulses. The DPs are normally terminated by a voltage-dependent potassium current, but when this is ...

journal_title：Brain research

authors： Berlind A

更新日期：1993-04-23 00:00:00

abstract：:Factors underlying paired-pulse facilitation (PPF) were studied by intracellular and field recordings of CA1 neurons in the hippocampal slice in vitro, following stimulation of the Schaffer collaterals apical dendritic afferents. Similar magnitudes of PPF were found using the slopes or peaks of the excitatory postsyna...

journal_title：Brain research

authors： Leung LS,Fu XW

更新日期：1994-07-04 00:00:00

abstract：:Vasopressin generates a voltage-gated, sodium-dependent current in facial motoneurons in brainstem slices. Reducing the extracellular calcium concentration from 2 to 0.01 mM caused a 30 to 120% increase in the amplitude of this current. Lowering extracellular magnesium also enhanced it, but less efficiently. In the ph...

journal_title：Brain research

authors： Alberi S,Dubois-Dauphin M,Dreifuss JJ,Raggenbass M

更新日期：1993-10-08 00:00:00

abstract：:A special feature of the extracellular matrix in adult brains of various species is the concentration of certain components around different sub-populations of neurones, giving rise to net-like structures termed perineuronal nets. Recently, some of these components have been identified but the function of these nets h...

journal_title：Brain research

authors： Haunso A,Celio MR,Margolis RK,Menoud PA

更新日期：1999-07-10 00:00:00

abstract：:Antisense oligodeoxynucleotide (AS ODN) probes directed against the alpha-subunit of different G-proteins have been used to differentiate feeding responses in rats elicited by different opioid agonists, including morphine, beta-endorphin and dynorphin. Furthermore, antisense probes directed against G(o)alpha, but not ...

journal_title：Brain research

authors： Hadjimarkou MM,Silva RM,Rossi GC,Pasternak GW,Bodnar RJ

更新日期：2002-11-15 00:00:00

abstract：:Thresholds of induction of heat shock protein (HSP) 70 and heat shock cognate protein (HSC) 70 mRNAs after transient global ischemia in gerbil brain were investigated by in situ hybridization using cloned cDNA probes selective for each mRNA species. In sham control brain, HSP70 mRNA was little present, while HSC70 mRN...

journal_title：Brain research

authors： Kawagoe J,Abe K,Kogure K

更新日期：1992-12-25 00:00:00