Abstract：
:Following electrophysiological techniques we investigated whether wallerian degeneration of the cat sural nerve may be influenced by (1) its peripheral connection and (2) the distance from the cell body. Distal stumps connected to their innervation sites peripherally showed less degeneration than proximal ones when isolated between two sections. However, when two isolated adjacent segments were produced by making 3 sections, the resulting degeneration was more pronounced in the distal segment. Thus, both the factors mentioned above appear to influence wallerian degeneration.
journal_name
Brain Resjournal_title
Brain researchauthors
Delgado-Lezama R,Muñoz-Martínez EJdoi
10.1016/0006-8993(90)91332-bsubject
Has Abstractpub_date
1990-08-13 00:00:00pages
152-4issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(90)91332-Bjournal_volume
525pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:To investigate the role of the amygdala in central regulation of pancreatic exocrine secretion, the effects of electrolytic lesions on pancreatic secretion were studied in rats. Small bilateral electrolytic lesions in amygdaloid body restricted to basolateral, medial and central nuclei were produced. Eight days after ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90770-x
更新日期：1985-08-05 00:00:00
abstract：:Neuroglobin (Ngb) and Cytoglobin (Cygb) are new members of the globin family and display heterotopic expression patterns. To examine the effect of different hypoxia profiles on expression of Ngb and Cygb in rodent brain, rats were exposed to either sustained hypoxia (SH; 10% O(2)) or intermittent hypoxia (IH; 10% and ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.04.063
更新日期：2006-06-22 00:00:00
abstract：:Two selectively bred lines of mice, one responding with high (HA) and the other with low analgesia (LA) to 3 min swims at 20 degrees C were compared with respect to naloxone ability to reverse such swim induced pain threshold elevation. Also, the analgesic effect of morphine was tested in both lines of mice. Naloxone ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91380-6
更新日期：1986-11-05 00:00:00
abstract：:Nodes of Ranvier in the central nervous system in mammals are characterized by the presence of perinodal astrocytic processes. This study examines the association between processes of radial glia and the axolemma at nodes of Ranvier in the spinal cord of the mature axolotl, an animal in which radial glia represent a l...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90595-m
更新日期：1991-05-17 00:00:00
abstract：:Our previous single unit and ultrastructural studies of visual cortex of dark-reared rats revealed an impairment of intracortical inhibitory mechanisms [2,3,5]. Neurochemical changes in inhibitory neurotransmitter and/or neuropeptides, such as gamma-aminobutyric acid (GABA) and somatostatin (SS), respectively, may con...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00553-3
更新日期：1995-08-21 00:00:00
abstract：:A role for glutamatergic signaling in the nucleus accumbens (NA) in both the expression and extinction of cocaine seeking has been suggested. The effects of extinction following cocaine self-administration on the expression and synaptosomal distribution of GluR1 and NMDAR1 glutamate receptor subunits in the NA shell a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.01.047
更新日期：2009-04-24 00:00:00
abstract：:One-day-old chicks were exposed for 60 min to either an imprinting stimulus or a dark-box. They were killed at 0, 1, 6 or 12 h after the end of this treatment, and the activities of acetylcholinesterase (AChE) and choline acetyltransferase (ChAc) assayed in the forebrain roof, forebrain base and midbrain. The activity...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(75)90271-1
更新日期：1975-07-11 00:00:00
abstract：:In the neonatal kitten, cuneate neurones activated by tactile stimulation of the forelimb foot pads are divisible into 3 functional classes each of which appears to receive its glabrous skin input selectively from a single class of tactile receptors. Their properties suggest that the functionally specific patterns of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(81)90081-x
更新日期：1981-06-01 00:00:00
abstract：:Application of 4-aminopyridine (4-AP) has previously been reported to produce different patterns of epileptiform discharges in entorhinal cortex (EC)-hippocampal slices: recurrent short discharges (RSDs) in hippocampal area CA1, seizure-like events (SLEs) and negative-going potentials (NGPs) in the medial entorhinal c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)02348-3
更新日期：2000-03-17 00:00:00
abstract：:Stress early in life puts the individual at a greater risk for developing mental disorders in adulthood. The animal model of maternal separation involves daily removal of pups from their mother over the early postnatal period and leads to several behavioral deficits in adults. Since this period corresponds to a time o...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.04.136
更新日期：2006-07-12 00:00:00
abstract：:Electrical activities of thin hippocampal sections of the guinea pig were studied in vitro during and after administration of black widow spider venom (BSV). In CA3 neurons, BSV induced spontaneous discharges which were suppressed by Co2+ or Mn2+. During BSV administration, trains of potential changes resembling excit...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90103-2
更新日期：1982-07-29 00:00:00
abstract：:The principal finding in this study is that the callosal projection to the occipital cortex in rats and mice follows a complex and highly reproducible pattern which has not previously been described in detail. In some regions, the callosal projection is associated with well defined cytoarchitectonic boundaries such as...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)91192-6
更新日期：1981-06-15 00:00:00
abstract：:Using a well-established model of binge-like ethanol treatment of rat pups on postnatal days (PD) 4-9, we found that maturation of GABAA receptor (GABAAR) miniature postsynaptic currents (mPSCs) was substantially blunted for medial septum/diagonal band (MS/DB) neurons in brain slices on PD 11-16. Ethanol reduced mPSC ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.04.054
更新日期：2013-07-03 00:00:00
abstract：:Methylazoxymethanol acetate (MAM)-induced cortical hypoplasia resulted in a 2-fold increase in the concentration of norepinephrine and its metabolite, 3-methoxyl-4-hydroxyphenylglycol sulfate, and a 26% decrease in the Bmax for the beta-receptor ligand, [3H]dihydroalprenolol (DHA) in the rat cortex. Chronic treatment ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(82)90195-x
更新日期：1982-08-01 00:00:00
abstract：:The GABA agonist muscimol, injected into the depressor area of the caudal ventrolateral medulla, increased blood pressure and increased the expression of the immediate early gene c-fos in the rostral ventral medulla (RVM) of the rat. The number of Fos-immunoreactive (Fos-IR) neurons seen in the RVM was increased 3-fol...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90056-6
更新日期：1994-05-16 00:00:00
abstract：:Quantitative autoradiographic analysis was used to identify regions in the brain of the male primate where androgen binding sites may be involved in the actions of testosterone. Three days after castration, adult male rhesus monkeys received a subcutaneous injection of either dihydrotestosterone propionate (DHTP, 20 m...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90456-3
更新日期：1989-11-13 00:00:00
abstract：:Hydrogen-rich water (HRW) has anti-oxidant activities, and it exerts neuroprotective effects during ischemia-reperfusion brain injury. Parvalbumin and hippocalcin are two calcium buffering proteins, which are involved in neuronal differentiation, maturation and apoptosis. The aim of this study was to investigate wheth...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.04.038
更新日期：2015-07-30 00:00:00
abstract：:Migraine headache is proposed to be mediated by nitric oxide (NO). Suitable mechanisms for eliciting increases in brain NO concentration in migraineurs have not yet been identified, although, animal models highlight cortical spreading depression (CSD) as a potential candidate. These studies have focused on CSD-associa...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)03191-7
更新日期：2001-02-09 00:00:00
abstract：:Emerging evidence that autophagy serves as a sweeper for toxic materials in the brain gives us new insight into the pathophysiology of neurodegenerative diseases. Autophagy is important for maintaining cellular homeostasis associated with metabolism. Some neurodegenerative diseases such as Alzheimer׳s and Parkinson׳s ...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2016.02.049
更新日期：2016-10-15 00:00:00
abstract：:Recently it has been reported that prolactin (PRL) exerts a neuroprotective effect against excitotoxicity in hippocampus in the rat in vivo models. However, the exact mechanism by which PRL mediates this effect is not completely understood. The aim of our study was to assess whether prolactin exerts neuroprotection ag...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2016.02.011
更新日期：2016-04-01 00:00:00
abstract：:The present study demonstrates changes in rat brain glial metabolism during the acute phase of epilepsy. Status epilepticus (SE) was induced using the lithium-pilocarpine model. Glial metabolism was measured with (14)C-acetate. Local cerebral blood flow and glucose metabolism were also measured using (14)C-N-isopropyl...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.10.074
更新日期：2010-01-22 00:00:00
abstract：:We have studied the effects of prenatal protein malnutrition on development of the hippocampal and frontal cortical electroencephalographic (EEG) activity. Using power spectral analyses in rats of several age groups we found that protein malnutrition, instituted prenatally and continued postnatally, produces marked al...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(85)90172-5
更新日期：1985-10-01 00:00:00
abstract：:Recordings of single unit activity before, during and after a 1-h continuous exposure were made from the mitral cell layer of the olfactory bulbs of awake rabbits. Thirteen complete 1-h exposures were performed using 8 neurons, while a further 6 neurons were lost before the end of the exposure. During the first few mi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90951-9
更新日期：1982-10-28 00:00:00
abstract：:Alpha-synuclein is a natively unfolded protein playing a key role in the regulation of several neuronal synaptic functions in physiological and pathological conditions. Many studies, over the past years, have shown that it is actively involved in PD pathophysiology. Alpha-synuclein is integrated in a complex network o...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2012.04.014
更新日期：2012-10-02 00:00:00
abstract：:Lithium is detected in the mouse brain with the aid of a (n,alpha) nuclear reaction. The resolving power is of a few micron. The detection efficiency is estimated in a first series of experiments with brain sections of progressively increasing thickness. This allows us to make the microlocation of lithium in the brain...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90239-5
更新日期：1980-10-13 00:00:00
abstract：:MicroRNAs (miRNAs) are a class of non-coding small RNAs that regulate the expression of target genes. They derive from pre-miRNAs that are enzymatically processed by dicer to ∼22 nucleotide mature miRNAs. Members of the pre-miRNA lethal-7 (let-7) are known to regulate cell proliferation and apoptosis. Here, we showed ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2018.01.032
更新日期：2018-04-15 00:00:00
abstract：:Unilateral olfactory nerve section was performed in the mouse. Three biochemical markers of the olfactory chemoreceptor neurons: carnosine, carnosine synthetase activity and the olfactory marker protein, were measured in the olfactory bulb and epithelium. Parallel observations were made by light microscopy as well as ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(77)90703-x
更新日期：1977-08-19 00:00:00
abstract：:Kernicterus is a bilirubin-induced encephalopathy in newborn. Its spectrum ranges from subtle extrapyramidal to acute encephalopathy and chronic posticteric sequelae. Current treatment of this serious problem is far from optimal. Taurine has been documented to have protective effects on neuronal cells against ischemia...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.01.036
更新日期：2010-03-12 00:00:00
abstract：:Immunohistochemical studies with an antiserum raised against tyrosine hydroxylase have allowed us to demonstrate a dense dopaminergic innervation of the globus pallidus in the squirrel monkey. This innervation derived mostly from two fascicles that detached themselves from the major ascending dopaminergic bundle arisi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90896-1
更新日期：1987-11-24 00:00:00
abstract：:We examined the degree of oxidative damage to the brain of mice transgenic for the mutation responsible for Huntington's disease. We found that there is a progressive increase in striatal lipid peroxidation (LP), that parallels the worsening of the neurological phenotype. We consider that these transgenic mice may pro...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02082-5
更新日期：2000-04-17 00:00:00
