Power spectral analysis of hippocampal and cortical EEG activity following severe prenatal protein malnutrition in the rat.

Abstract:

:We have studied the effects of prenatal protein malnutrition on development of the hippocampal and frontal cortical electroencephalographic (EEG) activity. Using power spectral analyses in rats of several age groups we found that protein malnutrition, instituted prenatally and continued postnatally, produces marked alterations in power spectral measures, i.e., alterations in peak theta frequency in the hippocampus during rapid eye movement (REM) sleep. Peak theta frequency was found to be significantly retarded in malnourished animals, especially during the preweaning period of development. Protein malnutrition, therefore, appears to affect mechanisms responsible for generating the tonic component of theta activity.

journal_name

Brain Res

journal_title

Brain research

authors

Morgane PJ,Austin K,Siok C,LaFrance R,Bronzino JD

doi

10.1016/0165-3806(85)90172-5

subject

Has Abstract

pub_date

1985-10-01 00:00:00

pages

211-8

issue

2

eissn

0006-8993

issn

1872-6240

journal_volume

354

pub_type

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