Methamphetamine stimulates the release of neuropeptide Y and noradrenaline from the paraventricular nucleus in rats.

abstract：:A small, unilateral, penetrating wound was placed in the dorsolateral portion of the lumbosacral spinal cord in immature rats. Although this wound did not extend into the central canal area, some cells forming the walls of this canal underwent proliferative activity as demonstrated by [3H]thymidine autoradiography. Th...

journal_title：Brain research

authors： Gilmore SA,Leiting JE

更新日期：1980-11-10 00:00:00

abstract：:Classical conditioning the rabbit nictitating membrane involves changes in synaptic and intrinsic membrane properties of cerebellar Purkinje cell dendrites, and a 4-aminopyridine (4-AP)-sensitive potassium channel underlies these membrane properties. We characterized I(A) currents in adult, rabbit Purkinje cells to de...

journal_title：Brain research

authors： Wang D,Schreurs BG

更新日期：2006-06-22 00:00:00

abstract：:Acute forebrain ischemia reduced protein kinase C (PKC) activity in the adult rat cortex, striatum and hippocampus by 60-70% after 20 min ischemia episodes, followed by 48 h of recirculation. Ischemia of 1 min, followed by recirculation, produced a less pronounced but significant decrease in PKC activity. The ischemia...

journal_title：Brain research

authors： Louis JC,Magal E,Brixi A,Steinberg R,Yavin E,Vincendon G

更新日期：1991-02-08 00:00:00

abstract：:Different doses of angiotensin II (AII) or angiotensin III (AIII) microinjections into the zona incerta have been studied on drinking of rats in separate experiments during the consequent 60-min-daily-drinking period. Also, the dipsogen power of only the effective dose of AII and AIII was compared to vehicle treated r...

journal_title：Brain research

authors： Bagi EE,Fekete E,Lénárd L

更新日期：2003-07-11 00:00:00

abstract：:By using enkephalin immunohistochemistry combined with retrograde fluorescent labelling, a great majority of neurons in the rat cerebellum sending their axons to the spinal cord were shown to contain enkephalin immunoreactivity. These neurons were numerous and clustered in the fastigial nucleus but far less abundant i...

journal_title：Brain research

authors： Ikeda M,Houtani T,Nakagawa H,Baba K,Kondoh A,Ueyama T,Yamamoto T,Gemba H,Sugimoto T

更新日期：1995-09-04 00:00:00

abstract：:Previous studies showed that electroacupuncture (EA) significantly attenuates inflammatory hyperalgesia in a complete Freund's adjuvant (CFA)-induced inflammatory pain rat model. The present study demonstrates that pretreatment with Derm-sap, a selective toxin for neurons that contain mu opioid receptor (MOR), specifi...

journal_title：Brain research

authors： Zhang RX,Wang L,Liu B,Qiao JT,Ren K,Berman BM,Lao L

更新日期：2005-06-28 00:00:00

abstract：:Various chemical and physical lesions were employed to elucidate the cellular localization of cholecystokinin (CCK) receptors in the rat caudate nucleus. A wide knife cut severing all caudal afferents reduced caudate CCK receptors by approximately 25%, indicating that some receptors lie on axons and (or) terminals of ...

journal_title：Brain research

authors： Hays SE,Meyer DK,Paul SM

更新日期：1981-08-24 00:00:00

abstract：:A study was undertaken of the possible relationship of the binding affinity of a series of anticholinergic psychotomimetic drugs to their psychopharmacological and anticholinergic effects. Binding was measured to brain homogenates and nerve endings using [3H]quinuclidinyl benzilate (QB), a highly potent psychotomimeti...

journal_title：Brain research

authors： Baumgold J,Abood LG,Aronstam R

更新日期：1977-03-25 00:00:00

abstract：:Cell death was due to activation of the receptor responsive to N-methyl-D-aspartate (NMDA). Even during a 30-min incubation, glutamate toxicity was unaffected by 5 microM CNQX and was greater than 90% blocked by 160 nM MK-801, a specific antagonist of the NMDA receptor. The extent of toxicity was dependent on the age ...

journal_title：Brain research

authors： Eimerl S,Schramm M

更新日期：1991-09-27 00:00:00

abstract：:A quantitative freeze-fracture study of perivascular astrocytic processes in rat cerebral cortex disclosed rapid disintegration of orthogonal arrays of the intramembrane particles in acute global ischemia. The process apparently preceded the development of astrocytic swelling. ...

journal_title：Brain research

authors： Suzuki M,Iwasaki Y,Yamamoto T,Konno H,Yoshimoto T,Suzuki J

更新日期：1984-05-21 00:00:00

abstract：:Kindling of the amygdaloid complex in rats results in an enhanced emotionality frequently expressed by an elevated anxiety and defensive attitude toward other animals. Defensive attitude may have important consequences in social context and if tested in a large space it may eventually lead to social withdrawal. To tes...

journal_title：Brain research

authors： Haimovici A,Wang Y,Cohen E,Mintz M

更新日期：2001-12-13 00:00:00

abstract：:Oral ENA713 (0.5, 1.5 and 4.5 mg/kg), an acetylcholinesterase inhibitor (AChEI), dose-dependently enhanced extracellular acetylcholine concentrations in the hippocampus of freely moving rats. This effect was paralleled by changes in both noradrenergic and dopaminergic transmission. In particular, ENA713 significantly ...

journal_title：Brain research

authors： Trabace L,Coluccia A,Gaetani S,Tattoli M,Cagiano R,Pietra C,Kendrick KM,Cuomo V

更新日期：2000-05-26 00:00:00

abstract：:The effects of lesions in the pars compacta of the substantia nigra of 4-week-old spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY) were studied on (a) changes in blood pressure during a period of 6 weeks following lesioning, and (b) dopamine and metabolite concentrations in the caudate nu...

journal_title：Brain research

authors： Linthorst AC,van Giersbergen PL,Gras M,Versteeg DH,de Jong W

更新日期：1994-03-14 00:00:00

abstract：:The present study examined if olfactory bulbectomy (OBX) altered defensive behaviors on the elevated plus-maze and the open-field differently in male and female rats. Similar increases in defensive behaviors in male and female rats were observed in both tests following OBX. No significant correlations were detected be...

journal_title：Brain research

authors： Stock HS,Hand GA,Ford K,Wilson MA

更新日期：2001-06-08 00:00:00

abstract：:Medium conditioned by NG108-15 neuroblastoma x glioma hybrid cells contains a factor which increases the number of acetylcholine receptor (AChR) aggregates on cultured myotubes. Protease digestion indicates that the AChR aggregation factor is a protein, and the molecular weight is from 150,000 to 250,000 daltons as es...

journal_title：Brain research

authors： Bauer HC,Daniels MP,Pudimat PA,Jacques L,Sugiyama H,Christian CN

更新日期：1981-03-30 00:00:00

abstract：:As measured by extracellular single-cell recording, the responses to adenosine triphosphate (ATP) by ATP-sensitive chemoreceptors (ATP cells) on the olfactory organ of the spiny lobster are markedly suppressed by adenosine diphosphate (ADP), adenosine monophosphate (AMP) and to a lesser extent, adenosine, when each is...

journal_title：Brain research

authors： Gleeson RA,Carr WE,Trapido-Rosenthal HG

更新日期：1989-09-11 00:00:00

abstract：:Schaffer collaterals of rat and mouse hippocampal slices were stimulated with bursts of pulses (300 Hz for 50 ms, 2-s intervals) for 30-s which caused a stable increase in the size of the population spike known as long-term potentiation. The release of adenosine triphosphate (ATP) was measured with a luciferase-lucife...

journal_title：Brain research

authors： Wieraszko A,Goldsmith G,Seyfried TN

更新日期：1989-04-24 00:00:00

abstract：:The postnatal development of the terminal Schwann cell, an analogue of the lamellar cell in cutaneous sensory receptors, was examined by histochemistry for non-specific cholinesterase and immunohistochemistry for S-100 protein in the periodontal Ruffini endings of the rat incisor. Double immunohistochemistry for S-100...

journal_title：Brain research

authors： Hayashi S,Nakakura-Ohshima K,Ohshima H,Noda T,Honma S,Wakisaka S,Maeda T

更新日期：2000-03-06 00:00:00

abstract：:The effects of acute and chronic phencyclidine (PCP) administration on neurotensin-like immunoreactivity (NTLI) were investigated in discrete regions of rat brain. Both acute and chronic administration of PCP induced high locomotor activity, stereotypy and ataxia. On PCP administration, NTLI decreased significantly in...

journal_title：Brain research

authors： Wachi M,Okuda M,Togashi S,Fuwano S,Miyashita O

更新日期：1985-05-06 00:00:00

abstract：:The synaptic relationship between neuronal structures reacting with antibodies to tyrosine hydroxylase (TH) and Leu- or Met-enkephalin (ENK) was studied by the 'mirror technique' in adjacent sections of rat neostriatum. TH-immunoreactive (TH-IR) axonal boutons surrounding the neural perikarya and proximal dendrites of...

journal_title：Brain research

authors： Kubota Y,Inagaki S,Kito S,Takagi H,Smith AD

更新日期：1986-03-05 00:00:00

abstract：:The effect of electrical stimulation of the prefrontal cortex (PFC) on acetylcholine (ACh) release in the dorsal striatum was investigated using on line in vivo microdialysis. ACh output was sampled before, during and after 20-min periods of 50 and 100 microA stimulation in awake, unrestrained rats. Both currents incr...

journal_title：Brain research

authors： Taber MT,Fibiger HC

更新日期：1994-03-14 00:00:00

abstract：:Extracellular recordings from 141 rat supraoptic nucleus neurons maintained in vitro in a perfused hypothalamic explant indicated that the excitability of 85% of cells was enhanced by the addition of 10-200 microM norepinephrine (NE) and the alpha-agonist methoxamine (MOXY), but not by isoproterenol, to the perfusion ...

journal_title：Brain research

authors： Randle JC,Bourque CW,Renaud LP

更新日期：1984-07-30 00:00:00

abstract：:We examined the distribution of choline acetyltransferase (ChAT) mRNA in the brain of six autopsied individuals by in situ hybridization with 35S-labeled human ChAT riboprobes. Neurons containing hybridization signal for ChAT mRNA were observed in the nucleus of the diagonal band of Broca, the basal nucleus of Meynert...

journal_title：Brain research

authors： Kasashima S,Muroishi Y,Futakuchi H,Nakanishi I,Oda Y

更新日期：1998-09-21 00:00:00

abstract：:Clinically, phenytoin is thought to be useful in controlling seizure activity by preventing it's spread from the focus to neighboring tissue. Experimentally, it has been suggested that phenytoin's principal action is no longer polysynaptic pathways with primary foci affected less than surrounding tissue. In this study...

journal_title：Brain research

authors： Chatt AB,Ebersole JS

更新日期：1984-03-19 00:00:00

abstract：:The effect of electrolytic lesion of the paraventricular nucleus of the hypothalamus (PVN) on yawning and penile erection induced by apomorphine, oxytocin and adrenocorticotropic hormone (ACTH1-24) was studied in male rats. In sham-operated rats, apomorphine (50 micrograms/kg s.c.), oxytocin (30 ng i.c.v.), and ACTH1-...

journal_title：Brain research

authors： Argiolas A,Melis MR,Mauri A,Gessa GL

更新日期：1987-09-22 00:00:00

abstract：:Hydroxyl free radical production seems to play an important role in the pathogenesis of Parkinson's disease. In the present study, we investigated the dopamine agonists pramipexole and pergolide as well as the nitrone compound S-PBN (N-tert-butyl-alpha-(2-sulfophenyl)nitrone) to reduce hydroxyl radical formation. Micr...

journal_title：Brain research

authors： Ferger B,Teismann P,Mierau J

更新日期：2000-11-17 00:00:00

abstract：:The Leu-enkephalin dalargin does not normally penetrate the blood brain barrier when given intravenously. Drug targeting to the brain was investigated by using poly(butylcyanoacrylate) nanoparticles which were coated with polysorbate 80. When injected intravenously in mice, dalargin-loaded nanoparticles coated with th...

journal_title：Brain research

authors： Schröder U,Sabel BA

更新日期：1996-02-26 00:00:00

abstract：:Dissociated 4-day (stage 23) chick embryo lumbar cord cells were cultured at low or high cell densities for 1 or 5 days in the presence or absence of added spinal neuronotrophic factor (supplied as RN22 Schwannoma conditioned medium, RCM). In low density, 1-day cultures neuronal survival was dependent on added RCM whe...

journal_title：Brain research

authors： Manthorpe M,Luyten W,Longo FM,Varon S

更新日期：1983-05-09 00:00:00

abstract：:Fast axonal transport and neuronal protein synthesis was studied in the isolated nervous system of Aplysia californica. The abdominal ganglion with attached pleural-abdominal connectives (PAC) was removed and the ganglion pulse-labelled with [35S]methionine for 30 min in vitro. The axon containing connectives were lig...

journal_title：Brain research

authors： Drake PF,Oblinger MM,Lasek RJ

更新日期：1985-04-15 00:00:00

abstract：:The organization and representation of conceptual knowledge in the brain remains a controversial issue in terms of both neuropsychological and imaging evidence. We report the results of a functional magnetic resonance study in which the role of the most debated dimensions (domain and feature type) was evaluated throug...

journal_title：Brain research

authors： Marques JF,Canessa N,Siri S,Catricalà E,Cappa S

更新日期：2008-02-15 00:00:00