Abstract：
:The effect of electrolytic lesion of the paraventricular nucleus of the hypothalamus (PVN) on yawning and penile erection induced by apomorphine, oxytocin and adrenocorticotropic hormone (ACTH1-24) was studied in male rats. In sham-operated rats, apomorphine (50 micrograms/kg s.c.), oxytocin (30 ng i.c.v.), and ACTH1-24 (10 micrograms i.c.v.) significantly increased the number of yawning and penile erection episodes. In PVN-lesioned rats, apomorphine- and oxytocin-, but not ACTH-induced responses were strongly reduced. These results confirm our previous observations showing that the PVN has a crucial role in the expression of yawning and penile erection induced by dopamino-mimetic drugs and oxytocin, and suggest that ACTH-derived peptides induce the above responses by a mechanism not involving PVN hypothalamic dopamine or oxytocin.
journal_name
Brain Resjournal_title
Brain researchauthors
Argiolas A,Melis MR,Mauri A,Gessa GLdoi
10.1016/0006-8993(87)91305-9subject
Has Abstractpub_date
1987-09-22 00:00:00pages
349-52issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(87)91305-9journal_volume
421pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Tissue accumulation of ornithine (Orn), homocitrulline (Hcit), ammonia and orotic acid (Oro) is the biochemical hallmark of patients affected by hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome, a disorder clinically characterized by neurological symptoms, whose pathophysiology is practically unknown....
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.07.021
更新日期：2009-09-29 00:00:00
abstract：:Superfusion of the hepatic portal vein with hypertonic saline solutions increases the electrical activity of the hypothalamo-neurohypophysial tract. Bilateral cervical vagotomy had no effect on this response in all rats studied. Section of the hepatic branch of the vagus abolished the hypothalamic response in only two...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90850-2
更新日期：1982-05-06 00:00:00
abstract：:Astrocytic gap junctions have been implicated in a variety of signaling pathways essential to normal brain function. However, no information exists on the prevalence of gap junction channels and their function in the aging brain. Here we have compared the expression of the two most abundant astrocytic gap junction pro...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02258-2
更新日期：2001-05-18 00:00:00
abstract：:Murine spinal cord primary mixed cultures were treated with the respiratory inhibitor, rotenone, to mimic hypoxic conditions. Under these conditions neurons rapidly underwent oncosis (necrosis) with a complete loss in viability occurring within 260 min; however, astrocytes, which accounted for most of the cell populat...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01086-0
更新日期：1999-03-13 00:00:00
abstract：:We examined the biochemical pathways whereby oral uridine-5'-monophosphate (UMP) increases membrane phosphatide synthesis in brains of gerbils. We previously showed that supplementing PC12 cells with uridine caused concentration-related increases in CDP-choline levels, and that this effect was mediated by elevations i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.07.054
更新日期：2005-10-05 00:00:00
abstract：:Initial studies found glutamate injury to murine spinal cultures (14-17 days in vitro) to reflect contributions of both NMDA and AMPA/kainate receptors. Subsequent experiments found the spinal cultures to be more sensitive than cortical cultures to injury from prolonged low level kainate exposures, and, unlike cortica...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00532-u
更新日期：1995-08-21 00:00:00
abstract：:A comparative study using membrane homogenate binding, autoradiography, and Western blot assays was carried out to determine the age-related changes in N-methyl-D-aspartate (NMDA) receptors in 4-, 12- and 24-month-old male Wistar rats, treated or not with vitamin E. Vitamin E treatment was 20 mg/kg i.p. daily for 15 d...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.09.008
更新日期：2004-12-03 00:00:00
abstract：:A substantial number of patients do not respond sufficiently to antidepressant drugs and are therefore often co-medicated with lithium as an augmentative strategy. Since lithium has been demonstrated to affect 5-HT neurotransmission, we examined the effect of acute and subchronic lithium on 5-HT levels after a challen...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02461-6
更新日期：2000-07-21 00:00:00
abstract：:We investigated the protective effect of subchronic treatment of the A2A receptor antagonist, SCH 58261 (0.01 mg/kg, i.p.), administered 5 min, 6 h and 15 h after permanent right middle cerebral artery occlusion (MCAo). Twenty-four hours after ischemia, an extensive pallid area, evaluated by cresyl violet staining, is...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.12.010
更新日期：2006-02-16 00:00:00
abstract：:Recent studies have shown that moving in synchrony with auditory stimuli boosts attention allocation and verbal learning. Furthermore rhythmic tones are processed more efficiently than temporally random tones ('timing effect'), and this effect is increased when participants actively synchronize their motor performance...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2017.11.022
更新日期：2019-08-01 00:00:00
abstract：:The postnatal development of the terminal Schwann cell, an analogue of the lamellar cell in cutaneous sensory receptors, was examined by histochemistry for non-specific cholinesterase and immunohistochemistry for S-100 protein in the periodontal Ruffini endings of the rat incisor. Double immunohistochemistry for S-100...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)02463-4
更新日期：2000-03-06 00:00:00
abstract：:Immunofluorescence on primary dissociated rat neuronal cultures (cortical, hippocampal, and cerebellar) and organotypic hippocampal cultures was used to investigate the pattern of distribution of cell-surface amyloid protein (APP). Antibodies directed against the extracellular (N-terminal) portion of APP or against th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00608-7
更新日期：1996-10-07 00:00:00
abstract：:The aim of the present study was to develop a model culture system for the study of factors controlling regeneration of axons from injured adult mammalian central nervous system. We show, for the first that retinal ganglion cells (RGC) dissociated from adult rat retina, regrow processes in vitro over long distances un...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(88)90204-0
更新日期：1988-07-01 00:00:00
abstract：:In the past few years a steadily increasing number of substances have been suggested to qualify as sleep-inducing factors. Most 'sleep factors' appear to exert their effects on slow-wave sleep. Recently, however, it has been shown that the cerebrospinal fluid (CSF) of sleep-deprived cats may contain a rapid eye moveme...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91561-1
更新日期：1986-10-15 00:00:00
abstract：:Sex steroid hormones regulate various neural functions that control vertebrate sociosexual behavior. A number of sex steroids can be synthesized de novo in the brain, including estrogens by the enzyme aromatase. Aromatase, the neuropeptides arginine vasotocin/vasopressin, and the monoamine neurotransmitter dopamine ha...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.09.017
更新日期：2006-12-18 00:00:00
abstract：:Amitriptyline, a representative tricyclic antidepressant, has been widely used for the treatment of neuropathic pain, such as post-herpetic and trigeminal neuralgia. In the present study, we investigated the effect of amitriptyline on glycinergic spontaneous miniature inhibitory postsynaptic currents (mIPSCs) in acute...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2012.03.030
更新日期：2012-05-21 00:00:00
abstract：:DDT [1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane] is a potent neurotoxicant in both vertebrate and invertebrate species. We have previously reported that neonatal exposure to DDT affects the muscarinic cholinergic receptors (MAChR) in the cerebral cortex in the neonatal mouse, leading to permanent disturbances in th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90144-x
更新日期：1992-06-12 00:00:00
abstract：:A lesion of the septum or a transection of the fimbria-fornix diminishes most, but not all, acetylcholinesterase (AChE) staining in the hippocampal formation. The residual AChE is located in the outer part of the molecular layer of the hippocampal CA1 zone and adjacent subicular field (zone 31). We report that followi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90583-8
更新日期：1983-08-08 00:00:00
abstract：:The present in vitro study was performed to characterize neurons within dorsal regions of the nucleus tractus solitarii (NTS), principally at the level of area postrema, and known to receive inputs predominantly from cardiovascular and respiratory afferents (i.e. cardiorespiratory NTS). This report describes 4 classes...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90358-t
更新日期：1993-02-26 00:00:00
abstract：:In the present study, we observed chronological changes of antioxidant-like protein 1 (AOP-1) in the gerbil hippocampal CA1 region after 5 min of transient forebrain ischemia using immunohistochemistry and western blot. AOP-1 was significantly altered in the CA1 region after transient ischemia. In the sham-operated gr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.09.022
更新日期：2005-11-16 00:00:00
abstract：:A gentle long-lasting handling produces persistent neurochemical and behavioural changes and attenuates the impairment in the behavioural reactivity to novelty induced by the prenatal exposure to diazepam (DZ) in adult male rat progeny. This study investigated the consequences of a late prenatal treatment with three G...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03282-1
更新日期：2002-10-25 00:00:00
abstract：:Tyrosine hydroxylase immunohistochemical examination of the mesencephalon of severely parkinsonian MPTP-treated macaque fascicularis monkeys revealed a marked loss of substantia nigra pars compacta (SNc) neurons in both medial and central portions of the nucleus with a relative sparing of neurons in the dorsal-most po...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90691-3
更新日期：1987-05-12 00:00:00
abstract：:In male hamsters mating behavior is dependent on chemosensory input from the main olfactory and vomeronasal systems, whose central pathways contain cell bodies and fibers of gonadotropin-releasing hormone (GnRH) neurons. In sexually naive males, vomeronasal organ removal (VNX), but not main olfactory lesions, impairs ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.10.078
更新日期：2010-03-04 00:00:00
abstract：:Application of the cholinergic agonist, carbachol, produced theta-like rhythmical waveforms, recorded in the stratum moleculare of the dentate gyrus in the cat hippocampal formation slices. This effect of carbachol was antagonized by atropine but not D-tubocurarine. These results provide first direct evidence that the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90223-v
更新日期：1992-04-24 00:00:00
abstract：:A new compound, 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP), has been evaluated as an excitatory amino acid receptor antagonist using electrophysiological assays and radioligand binding. In autoradiographic preparations, CPP reduces L-[3H]glutamate binding in regions of the hippocampus rich in N-m...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90128-9
更新日期：1986-09-10 00:00:00
abstract：:The lactating rat has been shown to lack a behavioral response and immediate early gene expression (cFos) in the hippocampus (Hipc) following intravenous or intracerebroventricular administration of an N-methyl-d-aspartate (NMDA) receptor agonist. The purpose of this study is to determine whether neurons in the Hipc h...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)01069-5
更新日期：1998-12-14 00:00:00
abstract：:We have shown previously that plasmin facilitated the generation of long-term potentiation (LTP) in CA1 and dentate region of rat hippocampus. In the present study, we investigated the effects of plasmin on postsynaptic currents in CA1 pyramidal neurons of rat hippocampal slices. Plasmin (100 nM) had no effect on NMDA...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00338-7
更新日期：1997-06-27 00:00:00
abstract：:The response of two populations of neurones in the substantia nigra (nigro-striatal compacta neurones and reticulata neurones) to microelectrophoretically administered putative neurotransmitters and stimulation of the ipsilateral striatum has been investigated in anaesthetized rats. There were marked differences betwe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90467-4
更新日期：1981-05-18 00:00:00
abstract：:Hippocampal corticosteroid receptors are regulated by corticosterone as well as by neurotransmitters, such as serotonin (5-HT). Studies have demonstrated that long-term changes in 5-HT levels are associated with alterations in hippocampal glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) number. However...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00371-v
更新日期：1995-06-26 00:00:00
abstract：:The existence of spinal neuron collaterals projecting to the intralaminar thalamic nuclei (ILN) and the periaqueductal gray (PAG) was determined in the rat using double-labeling, fluorescent, retrograde axoplasmic transport techniques. Distinctively double-labeled neurons, although not numerous, were found in the enti...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90731-6
更新日期：1986-02-12 00:00:00
