Abstract:
:The present study examined if olfactory bulbectomy (OBX) altered defensive behaviors on the elevated plus-maze and the open-field differently in male and female rats. Similar increases in defensive behaviors in male and female rats were observed in both tests following OBX. No significant correlations were detected between defensive behaviors and activity, supporting the hypothesis that some behavioral changes following OBX may be due to decreased defensive behaviors and not increased activity.
journal_name
Brain Resjournal_title
Brain researchauthors
Stock HS,Hand GA,Ford K,Wilson MAdoi
10.1016/s0006-8993(01)02421-0subject
Has Abstractpub_date
2001-06-08 00:00:00pages
242-6issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(01)02421-0journal_volume
903pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Saccadic adaptation is the progressive correction of systematic saccade targeting errors. When a saccade to a particular target is adapted, saccades within a spatial window around the target, the adaptation field, are affected as a function of their distance from the adapted target. Furthermore, previous studies sugge...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.07.040
更新日期:2007-10-03 00:00:00
abstract::The ability of crude cerebrum supernatant to stabilize, at a low temperature, cold-labile microtubules purified from beef brain was studied during development in the rat. The cold-stabilizing activity of the supernatant was low during the first postnatal week, rose significantly during the second postnatal week, and t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(88)90238-6
更新日期:1988-08-01 00:00:00
abstract::Activation of the immune system in response to either infection or lipopolysaccharide (LPS) produces neurophysiological, neuroendocrine and behavioral changes. Some of the physiological consequences of LPS are mediated by endogenous opioid peptides. The following studies were designed to characterize the effects of LP...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91908-9
更新日期:1994-06-13 00:00:00
abstract::A combination of electron microscopic autoradiography and immunocytochemistry was used to examine the connections between serotoninergic axons and dopaminergic neurons of the arcuate nucleus of the rat hypothalamus. The serotoninergic elements were identified after selective uptake of tritiated serotonin and the dopam...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90841-3
更新日期:1986-02-05 00:00:00
abstract::A study was made of the effects of electrochemically stimulating (ECS) and destroying the midbrain dorsal and median raphe nuclei on the estrogen-progesterone- (EP) induced surge of pituitary LH release in ovariectomized rats. ECS and lesions were produced simultaneously with anodal direct current through a chronicall...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90006-8
更新日期:1981-08-03 00:00:00
abstract::Activation of phospholipase C (PLC) coupled to phosphoinositide (PtdIns) hydrolysis occurs through one of the two pathways. One of the major pathways for the neurotransmitter signaling involves phosphoinositide (PtdIns) specific and G-protein dependent PLC-beta, which stimulates the formation of inositol triphosphate ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)01272-9
更新日期:1996-02-05 00:00:00
abstract::The subfornical organ, along with other regions of the lamina terminalis, may contain osmoreceptors and is likely to be a site of action of blood-borne angiotensin II. The neural pathways by which these stimuli lead to vasopressin secretion, have been suggested to extend from the subfornical organ to hypothalamic site...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90708-4
更新日期:1991-08-30 00:00:00
abstract::Quantitative autoradiographic analysis was used to identify regions in the brain of the male primate where androgen binding sites may be involved in the actions of testosterone. Three days after castration, adult male rhesus monkeys received a subcutaneous injection of either dihydrotestosterone propionate (DHTP, 20 m...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90456-3
更新日期:1989-11-13 00:00:00
abstract::The biochemical changes associated with conduction block following exogenous application of purified phospholipase A2 to bullfrog sciatic nerves were investigated. Nerves were treated with concentrations of phospholipase A2 needed to produce at least a 50% decrease in the compound action potential after a 2-2 1/2 h in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90354-9
更新日期:1986-05-14 00:00:00
abstract::In this study we examined the induction of heme oxygenase-1 (HO-1) in glia in the traumatized rat brain. HO-1 was immunolocalized in fixed sections of brain 3 h to 5 days after injury. Induction of this enzyme in astrocytes, microglia/macrophages, and oligodendrocytes was evaluated using immunofluorescent double label...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00680-4
更新日期:1996-10-14 00:00:00
abstract::The ability of hippocampal serotonergic (5-HT) axons to proliferate in response to damage by para-chloroamphetamine (PCA) was examined in this study. Synaptosomal uptake of 5-HT in the hippocampal formation was decreased to 40% of control 3 days after systemic administration of PCA. Six weeks after PCA, uptake values ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90281-d
更新日期:1992-04-17 00:00:00
abstract::Hippocampal slices were taken from 7-day-old rats and maintained in vitro for 1-3 weeks. The organization of intrahippocampal connections in these explants was studied by placing onto the tissue small crystals of horseradish peroxidase (HRP) soaked with the detergent Nonidet. Antero- and retrograde transport of HRP wa...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)91448-4
更新日期:1986-08-13 00:00:00
abstract::A monoclonal antibody was made using the spleen cells of a mouse immunized with chick synaptic membranes and designated as mAb 1D12. It immunoprecipitated 25% of the omega-conotoxin binding protein but no dihydropyridine binding protein solubilized from chick brain membranes. By immunoblotting, a polypeptide of 58-kDa...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90942-o
更新日期:1991-06-14 00:00:00
abstract::Purpurin, a retina-specific protein, is known to play a role in cell adhesion during development of the chicken retina. Although purpurin has been significantly detected in adult chicken retina, its function in the matured retina is not well understood. Therefore, to determine the expression pattern of purpurin in the...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.03.075
更新日期:2007-06-11 00:00:00
abstract::Sites which bind oxytocin and vasopressin with high affinity were detected in the brain and upper spinal cord of 12 human subjects, using in vitro light microscopic autoradiography. Tissue sections were incubated with tritiated vasopressin, tritiated oxytocin or an iodinated oxytocin antagonist. The ligand specificity...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90345-v
更新日期:1991-08-02 00:00:00
abstract::Growth hormone (GH) suppresses its own secretion by stimulating somatostatin (SRIF) release. Thus, the possible regulation of GH-releasing factor (GRF) and SRIF release and SRIF messenger ribonucleic acid (mRNA) by GH was studied in the hypothalamus of male rats in vitro. The median eminences (ME's) were incubated in ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)90014-e
更新日期:1993-09-24 00:00:00
abstract::We examined the responsiveness of rat vestibular ganglion neurons (VGNs) to exogenous neurotrophic factors, BDNF, NT-3, and GDNF, during postnatal development in dissociated cultures. VGNs were obtained from postnatal days (P) 1, 3, 7, and 14. After two days in culture, the survival of VGNs in control cultures without...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.06.058
更新日期:2011-08-23 00:00:00
abstract::This study was designed to assess effects of insulin-induced hypoglycemia on plasma and cerebrospinal fluid (CSF) levels of immunoreactive (ir) beta-endorphins, adrenocorticotropin (ACTH), cortisol, norepinephrine, insulin, and glucose in the conscious, overnight fasted dog. Dogs received either an intravenous infusio...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90475-1
更新日期:1988-08-23 00:00:00
abstract::When rabbit retinas are exposed in vitro to specific excitatory amino acid receptor agonists certain GABAergic amacrine cells are activated to cause a release of GABA. The GABA that is not released can be detected by immunohistochemistry. Exposure of tissues to kainate or NMDA each caused a characteristic change in th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91510-5
更新日期:1994-12-26 00:00:00
abstract::Antagonism of NMDA-mediated transmission by MK-801 has been shown to block long-term potentiation (LTP) in vitro and delay electrical kindling of the amygdala. The present experiment sought to examine the relationship between synaptic potentiation of the perforant path-granule cell synapse and development of perforant...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90064-i
更新日期:1990-06-11 00:00:00
abstract::Noradrenergic, serotoninergic and peptidergic nerves have been demonstrated in perivascular plexuses of vasa nervorum of sympathetic, parasympathetic and somatic nerve trunks. 5-Hydroxytryptamine-, vasoactive intestinal polypeptide- and substance P-containing fibers were found by immunohistochemistry to variable exten...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90344-5
更新日期:1984-06-25 00:00:00
abstract::Glutamate is the main excitatory neurotransmitter in the central nervous system. This amino acid mediates learning and memory processes acting through ionotropic and metabotropic receptor binding. Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that stimulate phospholipase C (PLC) or inhibit ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.01.010
更新日期:2007-06-11 00:00:00
abstract::Collagen is one of the best materials used for nerve guide preparation due to its biocompatibility and desirable tensile strength. In this work, we have compared regeneration and functional reinnervation after sciatic nerve resection with bioresorbable crosslinked collagen guides in 10 mm gap. The crosslinking was car...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.03.022
更新日期:2005-06-07 00:00:00
abstract::Amyloid beta-protein (A beta) is the major protein of cerebrovascular and plaque amyloid in Alzheimer's disease (AD). Extensive evidence has demonstrated abnormal protein phosphorylation in this disease. We investigated the effect of synthetic A beta with the amino-acid sequence corresponding to cerebrovascular A beta...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)90479-7
更新日期:1993-11-26 00:00:00
abstract::The functions of the claustrum are not well understood. Few studies explore its electrophysiological properties in awake animals. Here, we address this lacuna by recording spontaneous local field potential (LFP) activity in the anterior claustrum of rats freely exploring open field environments under differing conditi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2017.09.021
更新日期:2017-12-15 00:00:00
abstract::The exposure of cultured rat striatal neurons to L-DOPA caused marked cell death. The L-DOPA cytotoxicity was inhibited by the addition of Mg2+ to and by the removal of Ca2+ from the culture medium, and also by the application of tetrodotoxin. Moreover, prolonged application of L-DOPA increased the glutamate content i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)00908-6
更新日期:1997-10-10 00:00:00
abstract::Although an auditory area has been found over the exposed area of lobules VI-VIII in the posterior cerebellar vermis of the cat, there has been little information on its buried portion. This point should be of some concern, since very little of the brain tissue in lobules VI-VIII of the cerebellar cortex is exposed. W...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90825-g
更新日期:1991-07-12 00:00:00
abstract::The subthalamic nucleus receives serotonergic projections from the dorsal raphe nucleus. However, the role of serotonergic innervation in the activity of subthalamic neurons in vivo is unknown. The aim of the present work is to study the changes in the firing of subthalamic neurons in rats with 5,7-dihydroxytryptamine...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.02.052
更新日期:2007-05-29 00:00:00
abstract::Following transection of a peripheral nerve in mice, a newly synthesized neurotropic pyrimidine compound, MS-818 was administered intraperitoneally at a dose of 1 mg kg-1 b.wt. day-1. The film model experiments for analyzing the early growth of axonal regeneration suggested that MS-818 activated Schwann cells which mi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)01491-1
更新日期:1998-03-23 00:00:00
abstract::The molecular mechanisms regulating the retrograde axonal transport of nerve growth factor (NGF) are currently unknown. This study identifies some of the signalling events involved. The phosphoinositide 3-kinase (PI3-kinase) inhibitor wortmannin (1 nmol/eye) irreversibly inhibits the amount of 125I-betaNGF retrogradel...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00396-5
更新日期:1998-07-06 00:00:00