Abstract：
:The subfornical organ, along with other regions of the lamina terminalis, may contain osmoreceptors and is likely to be a site of action of blood-borne angiotensin II. The neural pathways by which these stimuli lead to vasopressin secretion, have been suggested to extend from the subfornical organ to hypothalamic sites of vasopressin production either directly or via synapses in an intervening nucleus such as the median preoptic nucleus. In the present study, cholera toxin conjugated to horseradish peroxidase (CT/HRP) or colloidal gold (CT/Au) has been injected, respectively, into the subfornical organ and supraoptic nucleus of the same animal. The anterograde and retrograde transport of the toxin from these two sites has made possible the identification, at the ultrastructural level, of a synapse in the median preoptic nucleus interposed in the pathway between the subfornical organ and the supraoptic nucleus. Moreover, the presence of retrogradely transported CT/HRP and CT/Au in the same neurone in the median preoptic nucleus indicates that some neurones in this nucleus have axons with collateral branches to both the subfornical organ and supraoptic nucleus. Either or both of these pathways may transmit information related to the tonicity of the blood or circulating levels of angiotensin II to sites in the hypothalamus.
journal_name
Brain Resjournal_title
Brain researchauthors
Oldfield BJ,Hards DK,McKinley MJdoi
10.1016/0006-8993(91)90708-4subject
Has Abstractpub_date
1991-08-30 00:00:00pages
13-9issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(91)90708-4journal_volume
558pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:During a recent study of the effects of photoreceptor degeneration on Muller cells, we observed that unlike glia from normal adult retinas, glia from degenerating rat retinas could be cultured and maintained in vitro for several weeks. Using a variety of cell type specific antisera, we show that at least 70% of cells ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91618-x
更新日期：1985-06-24 00:00:00
abstract：:The suspected functional role of dendritic spines as loci of neuronal plasticity (possibly memory and learning) is greatly enriched when active membrane properties are assumed at the spine head. Computations with reasonable electrical and structural parameter values (corresponding to an optimal range for spine stem re...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90333-6
更新日期：1985-01-28 00:00:00
abstract：:The research question was, do events arising from rhythmic passive movement of the human leg lead to inhibition of the H reflex pathway in the stationary leg contralateral to that movement? Further, as the angular velocity of the passive movement increases, does the contralateral reflex inhibition also increase? Stabl...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91303-a
更新日期：1993-02-12 00:00:00
abstract：:A substantial projection from the retina to the dorsal raphe nucleus (DRN) has been demonstrated in the Chilean degus, a diurnal/crepuscular hystricomorph rodent. Following intraocular injection of cholera toxin subunit B (CTB), immunocytochemically labeled CTB-positive axons and terminals were observed in all major r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02061-3
更新日期：2001-03-23 00:00:00
abstract：:Intraperitoneal (i.p.) administration of sulfated CCK octapeptide (CCK-8S) has been shown to induce changes in neuronal activity in the nucleus of the solitary tract (NTS) and area postrema (AP), sensory parts of the dorsal vagal complex (DVC), and in the paraventricular nucleus of the hypothalamus (PVN), as determine...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00865-2
更新日期：1997-10-03 00:00:00
abstract：:Adaptive decision making in dynamic social settings requires frequent re-evaluation of choice outcomes and revision of strategies. This requires an array of multiple cognitive abilities, such as working memory and response inhibition. Thus, the disruption of such abilities in schizophrenia can have significant implica...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.08.049
更新日期：2007-11-14 00:00:00
abstract：:This study was designed to assess effects of insulin-induced hypoglycemia on plasma and cerebrospinal fluid (CSF) levels of immunoreactive (ir) beta-endorphins, adrenocorticotropin (ACTH), cortisol, norepinephrine, insulin, and glucose in the conscious, overnight fasted dog. Dogs received either an intravenous infusio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90475-1
更新日期：1988-08-23 00:00:00
abstract：:In the dorsal horn of barbiturate-anaesthetized cats evidence was obtained for a different distribution of enkephalin-preferring and morphine-preferring receptors. When ejected electrophoretically from micropipettes, morphine reduced the nociceptive responses of neurones of laminae IV and V when administered in the su...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)91002-7
更新日期：1981-12-21 00:00:00
abstract：:The effect of anesthesia upon the functional outcome after experimental spinal cord injury (SCI) was studied in 221 rats subjected to graded weight drop contusion in the thoracic cord. Neurologic function was assessed in a blinded fashion for one week after injury using a modification of the method of Tarlov. The post...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91521-h
更新日期：1990-06-25 00:00:00
abstract：:Horseradish peroxidase was injected intracellularly into motoneurons responding to cutaneous stimulation of the central foot pad of the hind limb in cats. Three motoneurons were selected for detailed analysis: two excited by foot pad stimulation, and one postsynaptically inhibited by such stimulation. The overall leng...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90669-2
更新日期：1982-12-16 00:00:00
abstract：:Small reductions in temperature have been shown to improve neurologic recovery after ischemia. We have examined the effect of temperature on biochemical and physiological changes during hypoxia using rat hippocampal slices as a model system. The postsynaptic population spike recorded from the CA1 pyramidal cell region...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01944-7
更新日期：1999-10-09 00:00:00
abstract：:Immunohistochemical studies in rats have demonstrated dopaminergic input onto medium spiny neurons of the striatum. Medium spiny neurons, however, are known to consist of two major neuropeptide-specific types, those containing substance P (SP) and those containing enkephalin. Although both of these types have been sho...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90490-z
更新日期：1992-02-14 00:00:00
abstract：:The neuroprotective effects of N-stearoyl-L-tyrosine (NSTyr) on cognitive function and neuronal plasticity during chronic cerebral hypoperfusion (CCH) in rats were investigated. After induction of CCH, NSTyr was administered daily for 3 months intraperitoneally. Cognitive functions were evaluated by Morris water maze ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.02.037
更新日期：2010-04-14 00:00:00
abstract：:Axon-to-myelin transfer of lipids precursors have been studied in the rabbit optic system by intraocular injection of [32P]orthophosphate, [14C]glycerol and [3H]glycerol. Choline and ethanolamine phosphoglycerides and myelin showed increasing [32P]-radioactivity between 7 and 21 days following injection, while [3H]- a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90136-1
更新日期：1983-06-20 00:00:00
abstract：:Oa1 is the casual gene for ocular albinism-1 in humans. The gene product OA1, alternatively designated as GPR143, belongs to G-protein coupled receptors. It has been reported that OA1 is a specific receptor for 3, 4-dihydroxy- L-phenylalanine (DOPA) in retinal pigmental epithelium where DOPA facilitates the pigmentati...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.01.020
更新日期：2015-03-30 00:00:00
abstract：:Trigeminal hyperalgesia frequently appears in diabetic neuralgia altering the transmission of orofacial sensory information. This study was designed to explore the effects of trigeminal hyperalgesia in streptozotocin-induced diabetes monitoring the expression of nitric oxide synthase in the trigeminal ganglion cells. ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02235-6
更新日期：2000-05-19 00:00:00
abstract：:The effects of the sulfated octapeptide of cholecystokinin (CCK8-S), the non-sulfated homolog (CCK8-NS) as well as the C-terminal di-, tri- and tetrapeptidic fragments (respectively CCK2, CCK3 and CCK4) were studied in vitro in rat hippocampal slices by extracellular recording of the spontaneous action potential disch...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90776-7
更新日期：1988-06-07 00:00:00
abstract：:The distribution of radioactivity after injection of [3H]testosterone was studied in the forebrain of adult mice by thaw-mount autoradiography. Nuclear labeling was high in neurons in the dorsal part of the medial nucleus of the amygdala and in the dorsocaudal part of the bed nucleus of the stria terminalis. Low nucle...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90630-x
更新日期：1986-11-12 00:00:00
abstract：:We investigated the projection from the infralimbic division of the prefrontal cortex (area 25) to histaminergic neurons in the posterior hypothalamic area. Phaseolus vulgaris-leucoagglutinin (PHA-L) was injected in the prefrontal cortex of rats. Frozen brain sections were subjected to combined PHA-L and histidine dec...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90802-x
更新日期：1987-03-17 00:00:00
abstract：:The bag cell neurons of Aplysia are capable of generating an afterdischarge, which, in vivo, triggers egg-laying behavior. Pharmacologic elevation of cyclic AMP levels in isolated bag cell neurons has been shown to initiate repetitive firming similar to that seen during an afterdischarge, and to decrease outward curre...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91733-w
更新日期：1990-11-05 00:00:00
abstract：:Excitatory and inhibitory synapses may control neuronal output through a push-pull mechanism--that is, increases in excitation are coupled to simultaneous decreases in inhibition or vice versa. This pattern of activity is characteristic of excitatory and inhibitory vestibulospinal axons that mediate vestibulocollic re...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.03.065
更新日期：2010-05-28 00:00:00
abstract：:Altered dopamine regulation in the medial prefrontal cortex has been linked to drug abuse and disorders such as schizophrenia. Heterogeneous expression of the dopamine transporter, as well as the ability of the norepinephrine transporter to clear dopamine in the prefrontal cortex, delineates two potential sites for th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02542-8
更新日期：2002-05-17 00:00:00
abstract：:Using a double-labelling procedure, morphological relationships existing between dopaminergic and indoleaminergic neuronal systems in the rat brain were investigated. First, thanks to a tryptamine (T) antiserum, we visualized this indoleamine in all mesencephalic regions and showed that the T-immunoreactivity (IR) see...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91182-g
更新日期：1990-03-26 00:00:00
abstract：:The onset of adult hypothyroidism causes neuronal damage in the CA3 hippocampal region, which is attenuated by T(4) administration. We analyzed the expression of molecular proliferation markers (Cyclin D1 and PCNA), cellular damage-arrest (p53 and p21), and apoptosis (Bax/Bcl-2 index) in the hippocampus of hypothyroid...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.02.043
更新日期：2009-05-19 00:00:00
abstract：:Protease-activated receptors (PARs), G-protein-coupled receptors, are widely expressed in various tissues, where they participate in physiological and pathological processes, such as hemostasis, proliferation, tissue repair, and inflammation. Recently, we found that PARs were upregulated in the rat retina following op...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.04.040
更新日期：2005-06-21 00:00:00
abstract：:The present study combined masked priming with electrophysiological recordings to investigate orthographic priming effects with nonword targets. Targets were pronounceable nonwords (e.g., STRENG) or consonant strings (e.g., STRBNG), that both differed from a real word by a single letter substitution (STRONG). Targets ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.02.050
更新日期：2011-04-22 00:00:00
abstract：:The neurotoxic effects of chronic ethanol exposure were investigated in rat hippocampus by electrophysiological analysis of the Schaffer collateral-commissural input to stratum radiatum of CA1. Experimental animals were fed an ethanol-containing liquid diet for 20 weeks but were withdrawn from the special diet at leas...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90777-0
更新日期：1981-09-28 00:00:00
abstract：:In this paper the response of cerebral phosphate metabolism to mild hypoxia in young, medium and old rats has been studied via in-vivo [31P]nuclear magnetic resonance (NMR). It was found that the young adults (5-6 months) were more sensitive to this mild stress than either the mature adult (11-12 months) or senescent ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90536-2
更新日期：1989-03-13 00:00:00
abstract：:In view of the inconclusive findings relating the nuclei of the mammillary bodies (MB) with spatial memory, we evaluated the oxidative metabolic activity of the medial and lateral nuclei of the mammillary bodies (MB) after training young rats (30 days) of both sexes in the Morris water maze. Different groups were trai...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.03.025
更新日期：2004-06-11 00:00:00
abstract：:Individual vulnerability to the reinforcing effects of drugs appear to be a crucial factor in the development of addiction in humans. In the rat, individuals at risk for psychostimulant self-administration (SA) may be identified from their locomotor reactivity to a stress situation such as exposure to a novel environm...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)91452-7
更新日期：1991-12-13 00:00:00
