When less is more: feedback, priming, and the pseudoword superiority effect.


:The present study combined masked priming with electrophysiological recordings to investigate orthographic priming effects with nonword targets. Targets were pronounceable nonwords (e.g., STRENG) or consonant strings (e.g., STRBNG), that both differed from a real word by a single letter substitution (STRONG). Targets were preceded by related primes that could be the same as the target (e.g., streng-STRENG, strbng-STRBNG) or the real word neighbor of the target (e.g., strong-STRENG, strong-STRBNG). Independently of priming, pronounceable nonwords were associated with larger negativities than consonant strings, starting at 290ms post-target onset. Overall, priming effects were stronger and longer-lasting with pronounceable nonwords than consonant strings. However, consonant string targets showed an early effect of word neighbor priming in the absence of an effect of repetition priming, whereas pronounceable nonwords showed both repetition and word neighbor priming effects in the same time window. This pattern of priming effects is taken as evidence for feedback from whole-word orthographic representations activated by the prime stimulus that influences bottom-up processing of prelexical representations during target processing.


Brain Res


Brain research


Massol S,Midgley KJ,Holcomb PJ,Grainger J




Has Abstract


2011-04-22 00:00:00












  • Prolonged seizure suppression by a single implantable polymeric-TRH microdisk preparation.

    abstract::Thyrotropin-releasing hormone (TRH; Protirelin) is an endogenous neuropeptide known to have anticonvulsant effects in several seizure models and in intractable epileptic patients. Like most neuropeptides, its duration of action may be limited by a lack of sustained site-specific bioavailability. To attempt to provide ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Kubek MJ,Liang D,Byrd KE,Domb AJ

    更新日期:1998-11-02 00:00:00

  • Differentiation of neurochemical basis of stress-induced analgesia in mice by selective breeding.

    abstract::Two selectively bred lines of mice, one responding with high (HA) and the other with low analgesia (LA) to 3 min swims at 20 degrees C were compared with respect to naloxone ability to reverse such swim induced pain threshold elevation. Also, the analgesic effect of morphine was tested in both lines of mice. Naloxone ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Panocka I,Marek P,Sadowski B

    更新日期:1986-11-05 00:00:00

  • Quantitative autoradiography of adenosine receptors and NBTI-sensitive adenosine transporters in the brains and spinal cords of mice deficient in the mu-opioid receptor gene.

    abstract::There is a large body of evidence indicating important interactions between the adenosine and opioid systems in regulating pain at both the spinal and supraspinal level. Mice lacking the mu-opioid receptor (MOR) gene have been successfully developed and the animals show complete loss of analgesic responses to morphine...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Bailey A,Matthes H,Kieffer B,Slowe S,Hourani SM,Kitchen I

    更新日期:2002-07-05 00:00:00

  • Phosphatidylcholine protects neurons from toxic effects of amyloid β-protein in culture.

    abstract::Amyloid β-protein (Aβ) is the major component of extracellular plaques in the brains of patients with Alzheimer's disease. It has been suggested that the interaction of Aβ with membrane cholesterol is essential for Aβ to exert neurotoxicity; however, the effect of phospholipids, another major membrane lipid component,...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Ko M,Hattori T,Abdullah M,Gong JS,Yamane T,Michikawa M

    更新日期:2016-07-01 00:00:00

  • Eye and head movements during vestibular stimulation in the alert rabbit.

    abstract::Rabbits passively oscillated in the horizontal plane with a free hand tended to stabilize their head in space (re: earth-fixed surroundings) by moving the head on the trunk (neck angular deviation, NAD) opposite the passively imposed body rotation. The gain (NAD/body rotation) of head stabilization varied from 0.0 to ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Fuller JH

    更新日期:1981-02-02 00:00:00

  • A tripeptide protease inhibitor attenuates conditioned avoidance behavior.

    abstract::In a single 10-s training trial, hatchling chicks were conditioned to suppress their spontaneous peck response to a small spherical target by coating it with an aversive liquid. A 24-h test trial employing a dry target demonstrated a robust memory for the training manifested in passive avoidance behavior. Leupeptin, a...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Davis JL,Pico RM

    更新日期:1987-03-17 00:00:00

  • Sodium dodecylsulphate induces a breach in the blood-brain barrier and enables a West Nile virus variant to penetrate into mouse brain.

    abstract::A novel and convenient assay was used to determine the effect of recombinant Interleukin-2 (IL-2) on the function of the blood-brain barrier (BBB). The assay is based on a variant of the West Nile virus, WN-25, which had lost its neuroinvasiveness but not its neurovirulence. WN-25, when injected intravenously, can cau...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Kobiler D,Lustig S,Gozes Y,Ben-Nathan D,Akov Y

    更新日期:1989-09-04 00:00:00

  • Postnatal development of the endothelial system of the rat cerebellum using immunohistochemical techniques.

    abstract::The development of the endothelial system of the rat cerebellum was studied by immunohistochemical techniques with two antibodies specific of two membrane antigens characteristic of 'mature' endothelial cells. It appears that the maturation of endothelial cells is very late in the rat cerebellum. This absence of a ful...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Zanetta JP,Dontenwill M,Bricca G

    更新日期:1985-01-01 00:00:00

  • Biosynthesis of myelin-associated proteins in simian virus 40 (SV40)-transformed rat Schwann cell lines.

    abstract::In order to study the biosynthesis of myelin-associated proteins in Schwann cells, we have induced proliferation of cultured Schwann cells from neonatal rat sciatic nerve by transformation with Simian Virus 40 (SV40). Homogeneous transformed Schwann cell lines were established by single cell cloning. The transformed p...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Chen GL,Halligan NL,Lue NF,Chen WW

    更新日期:1987-06-23 00:00:00

  • The effect of unilateral basilar papilla removal upon nuclei laminaris and magnocellularis of the chick examined with [3H]2-deoxy-D-glucose autoradiography.

    abstract::The effect of unilateral basilar papilla removal on glucose uptake in the 2nd and 3rd order auditory nuclei in the chick's brain stem, nucleus magnocellularis and nucleus laminaris, respectively, was examined with [3H]2-deoxy-D-glucose (2-DG) autoradiography. The tissue was processed according to a thaw-mount techniqu...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Lippe WR,Steward O,Rubel EW

    更新日期:1980-08-25 00:00:00

  • Direct mapping of beta-adrenergic receptors in the rat central nervous system by a novel fluorescent beta-blocker.

    abstract::DL-N-(2-Hydroxy-3-napthyloxypropyl)-N'-dansylethylenediamine, dansyl analogue of propranolol (DAPN) is a novel fluorescent beta-adrenergic antagonist with high affinity to beta-receptors. The distribution pattern of DAPN fluorescence was studied in the rat central nervous system subsequent to its intravenous administr...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Atlas D,Melamed E

    更新日期:1978-07-14 00:00:00

  • NMDA glutamate receptor stimulation is required for the expression of D2 dopamine mediated responses in apomorphine primed 6-hydroxydopamine lesioned rats.

    abstract::Three priming injections with the D1/D2 dopamine agonist apomorphine permits a challenge with the D2 agonist quinpirole to elicit robust contralateral rotation and ipsilateral striatal Fos expression in 6-hydroxydopamine lesioned rats. Pretreatment with NMDA glutamate antagonists MK-801 or CPP dose-dependently attenua...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Pollack AE,Haisley EC

    更新日期:2001-04-06 00:00:00

  • Elevated TRH levels in pyriform cortex after partial and fully generalized kindled seizures.

    abstract::In a previous study we reported significant elevations of TRH in neocortex, hippocampus and combined amygdala/pyriform cortex in rats 48 h after the last of a series of stage 5 kindled seizures. In the present study, to determine whether the increases in TRH were proportional to the intensity of the convulsions, and t...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Meyerhoff JL,Bates VE,Kubek MJ

    更新日期:1990-08-13 00:00:00

  • Changes in fiber arrangement in the retinofugal pathway of the turtle Mauremys leprosa: an evolutionarily conserved mechanism.

    abstract::In spite of the numerous reports on the optic fiber distribution in the optic nerve and tract of vertebrates, there have been few studies of the visual pathway in reptiles. The arrangement of fibers in the optic nerve and tract of the turtle Mauremys leprosa was studied by placing a small granule of carbocyanine dye (...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Hidalgo-Sánchez M,Francisco-Morcillo J,Martín-Partido G

    更新日期:2007-12-01 00:00:00

  • Amygdaloid input to transiently tyrosine hydroxylase immunoreactive neurons in the bed nucleus of the stria terminalis of the rat.

    abstract::Several studies have reported transient expression of tyrosine hydroxylase in a subpopulation of neurons in the bed nucleus of stria terminalis of preadolescent rats. The tyrosine hydroxylase immunoreactive (TH) neurons, which are of small to medium size and often display a typical bipolar configuration, are confined ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Beltramino CA,Forbes MS,Swanson DJ,Alheid GF,Heimer L

    更新日期:1996-01-08 00:00:00

  • Exercise increases metabolic capacity in the motor cortex and striatum, but not in the hippocampus.

    abstract::Acute bouts of exercise have been shown to produce transient increases in regional cerebral glucose utilization, oxygen uptake, and cerebral blood flow in motor cortex, striatum, and hippocampus. The purpose of this study was to determine whether or not chronic exercise will cause long-term metabolic plasticity in bra...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: McCloskey DP,Adamo DS,Anderson BJ

    更新日期:2001-02-09 00:00:00

  • Modulation of extracellular monoamine transmitter concentrations in the hippocampus after weak and strong tetanization of the perforant path in freely moving rats.

    abstract::Hippocampal long-term potentiation (LTP) is considered as a cellular model of memory formation. Specific, electrical weak tetanization of distinct afferents such as the medial perforant path results in a short-lasting, protein synthesis-independent early-LTP (up to 4 h) within the dentate gyrus. A stronger tetanizatio...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Neugebauer F,Korz V,Frey JU

    更新日期:2009-06-01 00:00:00

  • Regional localization of agmatine in the rat brain: an immunocytochemical study.

    abstract::The distribution of agmatine (decarboxylated arginine) was mapped in the central nervous system (CNS) in the rat. Agmatine-like immunoreactivity was identified by light microscopy, exclusively in the cytoplasm of neuronal perikarya. Immunoreactive neurons were present in the cerebral cortex, predominantly within lamin...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Otake K,Ruggiero DA,Regunathan S,Wang H,Milner TA,Reis DJ

    更新日期:1998-03-16 00:00:00

  • WITHDRAWN: Transplantation of bone mesenchymal stem cells containing the nerve growth factor gene in adult rat brain with Fimbria Fornix lesion.

    abstract::Bone marrow-derived mesenchymal stem cells (BMSCs) are a promising source for cell-based treatment of brain injury, but the therapy of BMSCs is restricted by low cell survival. We examined whether nerve growth factor (NGF) improve BMSCs viability in the brain with Fimbria-Fornix lesion (FF). After transduction of NGF ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Leng SL,Fan WG,Qu HG,Xu SC,Zhong WY,Zhang WY,Zeng JQ,Long DH,He HW

    更新日期:2009-01-19 00:00:00

  • Sturctural homologies in mammalian neurofilament proteins.

    abstract::Antibody has been prepared to purified neurofilament protein extracted from calf brain. This antibody crossreacts with brain and nerve extracts from all mammals tested but fails to crossreact with frog, cod and chicken nerve extracts. Thus the serologic homology of these neurofilament proteins appears to be restricted...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Davison PF,Hong BS

    更新日期:1977-10-07 00:00:00

  • Ontogenesis of chromogranin A and B and catecholamines in rat adrenal medulla.

    abstract::The ontogenesis of chromogranins A and B and catecholamines was investigated for rat adrenal medulla. The chromogranins, the major secretory peptides of chromaffin granules, were characterized by one- and two-dimensional immunoblotting. Chromogranin B appeared identical in fetal and postnatal adrenals. On the other ha...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Schober M,Fischer-Colbrie R,Winkler H

    更新日期:1989-01-23 00:00:00

  • Protein phosphorylation in rat hippocampal synaptic plasma membranes in response to neurohypophyseal peptides.

    abstract::The effect of arginine vasopressin (AVP) on protein phosphorylation in rat hippocampal synaptic plasma membranes (SPM) was examined. With a crude SPM preparation, AVP (10(-8)-10(-5) M) stimulated phosphorylation of a number of proteins which included a brain-specific protein of 48 kDa called B50 or protein F1, which i...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Hinko A,Kim Y,Pearlmutter AF

    更新日期:1986-10-01 00:00:00

  • Properties of otolith-related vestibular nuclear neurons in response to bidirectional off-vertical axis rotation of the rat.

    abstract::In decerebrate rats, the responses of tilt-sensitive neurons in the lateral and descending vestibular nuclei were studied during constant velocity 10 degrees off-vertical axis rotations (OVAR) in the clockwise (VW) and counterclockwise (CCW) directions. Seventy three otolith-related units showed a sinusoidal position-...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Lai CH,Chan YS

    更新日期:1995-09-25 00:00:00

  • Myelin basic protein has lectin-like properties.

    abstract::Myelin basic proteins (MBP) obtained from bovine, guinea pig and human nervous tissues exhibited hemagglutinating activity for erythrocytes of several animal species. The activity to each erythrocyte was actually equal among the 3 MBPs. With bovine MBP and chicken erythrocytes, the hemagglutinating activity did not re...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Ikeda K,Yamamoto T

    更新日期:1985-03-11 00:00:00

  • Striatal oxidative damage parallels the expression of a neurological phenotype in mice transgenic for the mutation of Huntington's disease.

    abstract::We examined the degree of oxidative damage to the brain of mice transgenic for the mutation responsible for Huntington's disease. We found that there is a progressive increase in striatal lipid peroxidation (LP), that parallels the worsening of the neurological phenotype. We consider that these transgenic mice may pro...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Pérez-Severiano F,Ríos C,Segovia J

    更新日期:2000-04-17 00:00:00

  • Decreased norepinephrine in the ventral lamina terminalis region is associated with angiotensin II drinking response deficits following local 6-hydroxydopamine injections.

    abstract::Previous studies have demonstrated that punctate injections of 6-hydroxydopamine (6-OHDA) into structures along the ventral lamina terminalis reduce drinking responses elicited by angiotensin II (ANG II). The purpose of the present study was to extend these findings by quantifying the catecholamine depletions that are...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Cunningham JT,Johnson AK

    更新日期:1989-02-20 00:00:00

  • Prolonged seizure activity leads to increased Protein Kinase A activation in the rat pilocarpine model of status epilepticus.

    abstract::Status epilepticus is a life-threatening form of seizure activity that represents a major medical emergency associated with significant morbidity and mortality. Protein Kinase A is an important regulator of synaptic strength that may play an important role in the development of status epilepticus-induced neuronal path...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Bracey JM,Kurz JE,Low B,Churn SB

    更新日期:2009-08-04 00:00:00

  • Dopaminergic regulation of prolactin and growth hormone synthesis in rat pituitary tumor cells.

    abstract::The dopaminergic regulation of prolactin (PRL) and growth hormone (GH) synthesis were studied in monolayer cultures of rat pituitary tumor (GH3) cells. PRL synthesis could not be inhibited by dopamine at concentrations ranging from 10(-9) to 10(-5) M. Bromocriptine inhibited PRL synthesis only at the very high concent...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Cheung CY,Melmed S,Braunstein GD

    更新日期:1983-06-27 00:00:00

  • Cholinergic differentiation of clonal rat pheochromocytoma cells (PC12) induced by retinoic acid: increase of choline acetyltransferase activity and decrease of tyrosine hydroxylase activity.

    abstract::The effects of retinoic acid (RA), a naturally occurring metabolite of vitamin A, on the growth, morphology and neurochemical differentiation of the PC12 clone of rat pheochromocytoma cells were investigated. RA added to the medium inhibited the growth of PC12 cells in a dose-dependent manner up to 10 microM without a...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Matsuoka I,Mizuno N,Kurihara K

    更新日期:1989-11-13 00:00:00

  • Distinguishing the processing of gestures from signs in deaf individuals: an fMRI study.

    abstract::Manual gestures occur on a continuum from co-speech gesticulations to conventionalized emblems to language signs. Our goal in the present study was to understand the neural bases of the processing of gestures along such a continuum. We studied four types of gestures, varying along linguistic and semantic dimensions: l...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Husain FT,Patkin DJ,Thai-Van H,Braun AR,Horwitz B

    更新日期:2009-06-18 00:00:00