Establishment of Muller cell cultures from adult rat retina.

Abstract:

:During a recent study of the effects of photoreceptor degeneration on Muller cells, we observed that unlike glia from normal adult retinas, glia from degenerating rat retinas could be cultured and maintained in vitro for several weeks. Using a variety of cell type specific antisera, we show that at least 70% of cells in these cultures are derived from Muller cells.

journal_name

Brain Res

journal_title

Brain research

authors

Sarthy PV

doi

10.1016/0006-8993(85)91618-x

subject

Has Abstract

pub_date

1985-06-24 00:00:00

pages

138-41

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(85)91618-X

journal_volume

337

pub_type

杂志文章
  • GABAergic miniature postsynaptic currents in septal neurons show differential allosteric sensitivity after binge-like ethanol exposure.

    abstract::Binge-like ethanol treatment of septal neurons blunts GABAAR-mediated miniature postsynaptic currents (mPSCs), suggesting it arrests synaptic development. Ethanol may disrupt postsynaptic maturation by blunting feedback signaling through immature GABAARs. Here, the impact of ethanol on the sensitivity of mPSCs to zolp...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.03.023

    authors: DuBois DW,Trzeciakowski JP,Parrish AR,Frye GD

    更新日期:2006-05-17 00:00:00

  • 1-methyl-4-phenyl-pyridinium ion (MPP+) causes DNA fragmentation and increases the Bcl-2 expression in human neuroblastoma, SH-SY5Y cells, through different mechanisms.

    abstract::Apoptosis has been shown to be induced by some pathological stimuli. MPP+ is a neurotoxin and an inducer of parkinsonism. When SH-SY5Y cells, human neuroblastoma cell line, were treated with MPP+, cell death estimated by lactate dehydrogenase (LDH) leakage assay occurred. The cell death was associated with the DNA fra...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)01120-x

    authors: Itano Y,Nomura Y

    更新日期:1995-12-18 00:00:00

  • Paraventricular nucleus lesion prevents yawning and penile erection induced by apomorphine and oxytocin but not by ACTH in rats.

    abstract::The effect of electrolytic lesion of the paraventricular nucleus of the hypothalamus (PVN) on yawning and penile erection induced by apomorphine, oxytocin and adrenocorticotropic hormone (ACTH1-24) was studied in male rats. In sham-operated rats, apomorphine (50 micrograms/kg s.c.), oxytocin (30 ng i.c.v.), and ACTH1-...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)91305-9

    authors: Argiolas A,Melis MR,Mauri A,Gessa GL

    更新日期:1987-09-22 00:00:00

  • Kainic acid responses and toxicity show pronounced Ca2+ dependence.

    abstract::Responses of pyramidal neurons to ionophoretic kainate, quisqualate and N-methyl aspartate were studied in a submerged rat piriform cortex slice as a function of Ca2+ and Mg2+ concentrations. The results suggest that the channel activated by kainate is unusually influenced by Ca2+, excitotoxicity is Ca2+-dependent and...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90989-8

    authors: Hori N,Ffrench-Mullen JM,Carpenter DO

    更新日期:1985-12-09 00:00:00

  • Sprouting in the hippocampus is accompanied by an increase in coated vesicles.

    abstract::Coated vesicles within dentate gyrus granule cell dendrites were found free in the cytoplasm and also attached to the smooth endoplasmic reticulum and plasmalemma. Coated vesicles began increasing in number 40-48 h following partial dendritic deafferentation. This increase continued up to 15-30 days postlesion, after ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90076-7

    authors: McWilliams JR,Lynch G

    更新日期:1981-04-27 00:00:00

  • Differential expression of FGF-2 isoforms in the rat adrenal medulla during postnatal development in vivo.

    abstract::Basic fibroblast growth factor (FGF-2) isoforms of the adrenal medulla are differentially expressed during rat postnatal development. While the 18 and 23 kDa isoforms continuously rise towards the adult expression level, the 21 kDa isoform displays a peak expression at postnatal day 28. The peak expression of the 21 k...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00341-7

    authors: Meisinger C,Grothe C

    更新日期:1997-05-23 00:00:00

  • Temporal patterns of the embryonic intermediate filaments nestin and vimentin expression in the cerebral cortex of adult rats after cryoinjury.

    abstract::The expression of two embryonic intermediate filaments, nestin and vimentin, in the rat brain at days 0 (control), 1, 4, 7 and 14 post-cryoinjury was studied to elucidate their roles in brain injury. Western blot analysis showed that both nestin and vimentin expressions in the ipsilateral cerebral cortex were signific...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.09.022

    authors: Moon C,Ahn M,Kim S,Jin JK,Sim KB,Kim HM,Lee MY,Shin T

    更新日期:2004-12-03 00:00:00

  • Estrogen-dependent post-translational change in the nitric oxide system may mediate the leptin action on LH and prolactin secretion.

    abstract::Gonadotrophin-releasing hormone (GnRH) neurons do not express the leptin receptor (OB-R) in the medial preoptic area (MPOA) and the medial basal hypothalamus (MBH). We assessed whether the effect of leptin on the secretion of luteinizing hormone (LH), follicle stimulating hormone (FSH) and prolactin (PRL) in proestrus...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2015.02.001

    authors: Del Bianco-Borges B,Franci CR

    更新日期:2015-04-16 00:00:00

  • The adenosine binding enhancer, PD 81,723, inhibits epileptiform bursting in the hippocampal brain slice.

    abstract::The effects of adenosine and the adenosine binding enhancer, PD 81,723, on low magnesium-induced bursting in the in vitro hippocampal slice were examined. Extracellular recordings were obtained from the CA3 pyramidal cell layer while electrically stimulating in the stratum radiatum under low magnesium perfusion. Adeno...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91604-q

    authors: Janusz CA,Berman RF

    更新日期:1993-08-13 00:00:00

  • Localization of angiotensin-converting enzyme, angiotensin II, angiotensin II receptor subtypes, and vasopressin in the mouse hypothalamus.

    abstract::The hypothalamic angiotensin II (Ang II) system plays an important role in pituitary hormone release. Little is known about this system in the mouse brain. We studied the distribution of angiotensin-converting-enzyme (ACE), Ang II, Ang II receptor subtypes, and vasopressin in the hypothalamus of adult male mice. Autor...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00220-5

    authors: Jöhren O,Imboden H,Häuser W,Maye I,Sanvitto GL,Saavedra JM

    更新日期:1997-05-23 00:00:00

  • Distinct cellular compartment of cyclin-dependent kinase 5 (Cdk5) and neuron-specific Cdk5 activator protein (p35nck5a) in the developing rat cerebellum.

    abstract::We have elucidated the spatial and temporal localization of Cdk5 and p35nck5a in the developing rat postnatal cerebellum. Both proteins were highly expressed in cell bodies of post mitotic and immature neurons. The localization of Cdk5 in cellular compartment was changed from cell body to the axon in development. On t...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:

    authors: Matsushita M,Tomizawa K,Lu YF,Moriwaki A,Tokuda M,Itano T,Wang JH,Hatase O,Matsui H

    更新日期:1996-09-23 00:00:00

  • Abnormal resting-state functional connectivity of posterior cingulate cortex in amnestic type mild cognitive impairment.

    abstract::Amnestic type mild cognitive impairment (aMCI) refers to a transitional stage between normal aging and Alzheimer's disease (AD). Whilst posterior cingulate cortex (PCC) is believed to have a key role in a default network and be involved in the pathophysiology of AD, few studies have investigated whole-brain functional...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.09.028

    authors: Bai F,Watson DR,Yu H,Shi Y,Yuan Y,Zhang Z

    更新日期:2009-12-11 00:00:00

  • Cerebral extracellular lactate concentration and blood flow during chemical stimulation of the nucleus tractus solitarii in anesthetized rats.

    abstract::The extracellular lactate concentration and blood flow in the cerebral cortex of urethane-anesthetized, paralyzed and artificially ventilated rats were monitored continuously and simultaneously using an enzyme electrode and a laser Doppler flowmeter (LDF), respectively, during chemical stimulation of the nucleus tract...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(96)01428-x

    authors: Ikegami Y,Maeda M,Yokota A,Hayashida Y

    更新日期:1997-05-30 00:00:00

  • Long-term enhancement of entorhinal-dentate evoked potentials following 'modified' ECS in the rat.

    abstract::Electroconvulsive therapy (ECT) is widely used as a treatment for drug-resistant depression. The animal analogue of ECT is electroconvulsive shock (ECS) seizures. We have recently shown that repeated ECS seizures cause a long-lasting, perhaps permanent, enhancement in entorhinal-dentate evoked potentials in the rat. O...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00555-6

    authors: Gombos Z,Mendonça A,Racine RJ,Cottrell GA,Burnham WM

    更新日期:1997-08-22 00:00:00

  • Effects of nitric oxide on the retinal spreading depression.

    abstract::The retinal spreading depression has been used as a tool to investigate the action of nitric oxide (NO) as a diffusible neurotransmitter which in many cases acts by raising the cGMP level in target cells. The role of NO as a vasodilating agents has been well-established and it has been suggested that the vasodilatatio...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00737-b

    authors: Ulmer HJ,de Lima VM,Hanke W

    更新日期:1995-09-11 00:00:00

  • The role of GABA in NMDA-dependent long term depression (LTD) of rat medial vestibular nuclei.

    abstract::The role of GABA in NMDA-dependent long term depression (LTD) in the medial vestibular nuclei (MVN) was studied on rat brainstem slices. High frequency stimulation (HFS) of the primary vestibular afferents induces a long lasting reduction of the polysynaptic (N2) component of the field potentials recorded in the dorsa...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00895-w

    authors: Grassi S,Della Torre G,Capocchi G,Zampolini M,Pettorossi VE

    更新日期:1995-11-20 00:00:00

  • Noradrenaline stimulates somatostatin release from incubated slices of the amygdala and the hypothalamic preoptic area.

    abstract::Neurotransmitter effects were studied on in vitro release of immunoreactive somatostatin (SRIF) from slices prepared from several regions of the rat brain: mediobasal hypothalamus (MBH), preoptic anterior hypothalamic area (POA) and amygdaloid complex (AMY). Potassium (K+, 56 mM) stimulated SRIF release in all structu...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90523-0

    authors: Epelbaum J,Tapia-Arancibia L,Kordon C

    更新日期:1981-06-29 00:00:00

  • Pyramidal influences on ventral thalamic nuclei in the cat.

    abstract::In pericruciate cortex-ablated 'pyramidal cats', discharge changes in single neurons of ventral thalamic nuclei were studied, following stimulation of ipsilateral medullary (MPT) and contralateral cervical (CPT) pyramidal tract. It was seen that cells in ventrolateral nucleus, ventroanterior nucleus and ventromedial n...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)90187-7

    authors: Giuffrida R,Li Volsi G,Pantó MR,Perciavalle V,Urbano A

    更新日期:1983-11-21 00:00:00

  • Biosynthesis of myelin-associated proteins in simian virus 40 (SV40)-transformed rat Schwann cell lines.

    abstract::In order to study the biosynthesis of myelin-associated proteins in Schwann cells, we have induced proliferation of cultured Schwann cells from neonatal rat sciatic nerve by transformation with Simian Virus 40 (SV40). Homogeneous transformed Schwann cell lines were established by single cell cloning. The transformed p...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)91324-2

    authors: Chen GL,Halligan NL,Lue NF,Chen WW

    更新日期:1987-06-23 00:00:00

  • Modification of the circadian body temperature rhythm of the spontaneously hypertensive rat during and following cessation of continuous clonidine infusion.

    abstract::The effects of continuous clonidine infusion (10 micrograms/kg/h for 10 days) and the cessation of this infusion on the circadian body temperature rhythm of the spontaneously hypertensive (SH) rat were examined. This circadian rhythm was blunted significantly during the infusion of clonidine. The fall in body temperat...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91088-7

    authors: Lewis SJ,Maccarrone C,Jarrott B

    更新日期:1986-10-22 00:00:00

  • Fluoxetine induces vasopressin and oxytocin abnormalities in food-restricted rats given voluntary exercise: relationship to anorexia nervosa.

    abstract::Anorexia nervosa is associated with vasopressin, oxytocin and serotonin abnormalities. Because of the relationship between exercise and anorexia nervosa, we explored the weight-loss syndrome produced by wheel running in food-deprived rats. Its effects on regional vasopressin and oxytocin concentrations were determined...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91659-g

    authors: Aravich PF,Rieg TS,Ahmed I,Lauterio TJ

    更新日期:1993-05-28 00:00:00

  • Ultrastructure of blood-brain barrier and blood-spinal cord barrier in SOD1 mice modeling ALS.

    abstract::The purpose of this study was to determine the ultrastructure of the blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) in G93A SOD1 mice modeling ALS at different stages of disease. Electron microscope examination of brainstem, cervical and lumbar spinal cords was performed in ALS mice at early and late s...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.04.044

    authors: Garbuzova-Davis S,Haller E,Saporta S,Kolomey I,Nicosia SV,Sanberg PR

    更新日期:2007-07-09 00:00:00

  • Sustained elevation in hippocampal NGF-like biological activity following medial septal lesions in the rat.

    abstract::Several laboratories have documented an increase in hippocampal nerve growth factor (NGF) levels, measured with biological or immunological assays, within 1-2 weeks following septal lesions or fimbria/fornix transections. In the present study we have determined the increase in NGF-like biological activity in medium co...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90254-0

    authors: Collins F,Crutcher KA

    更新日期:1989-06-26 00:00:00

  • Ether anesthesia differentially affects the content of prepro-corticotropin-releasing hormone, prepro-neurotensin/neuromedin N and prepro-enkephalin mRNAs in the hypothalamic paraventricular nucleus of the rat.

    abstract::The content of the mRNAs that code for prepro-corticotropin releasing hormone (ppCRH), prepro-neurotensin/neuromedin N (ppNT/NMN) and prepro-enkephalin (ppENK) was measured using in situ hybridization histochemistry in the various subdivisions of the hypothalamic paraventricular nucleus (PVH) 4 h after a bout of ether...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90080-f

    authors: Watts AG

    更新日期:1991-03-29 00:00:00

  • Learning impairment by minimal cortical injury in a mouse model of Alzheimer's disease.

    abstract::Brain injury accelerates amyloid-β (Aβ) deposits and exacerbates Alzheimer's disease (AD). Accumulation of intracellular soluble Aβ impairs cognition prior to emergence of Aβ plaques. However, it is not known whether brain injury affects learning impairment attributable to intracellular soluble Aβ. We made a small inj...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2016.02.017

    authors: Zou J,Wang M,Uchiumi O,Shui Y,Ishigaki Y,Liu X,Tajima N,Akai T,Iizuka H,Kato N

    更新日期:2016-04-15 00:00:00

  • Neuron-specific enolase-like immunoreactivity in inner hair cells but not outer hair cells in the guinea pig organ of Corti.

    abstract::Neuron-specific enolase (NSE) has been localized only in neurons and cells with characteristics of neurons. The immunocytochemical localization of NSE was examined in guinea pig cochleae to determine if hair cells, which have some neuronal characteristics, would show NSE-like immunoreactive labeling. NSE-like immunore...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)91541-0

    authors: Altschuler RA,Reeks KA,Marangos PJ,Fex J

    更新日期:1985-02-18 00:00:00

  • Age-related changes in the neurosensory epithelium of the mouse vomeronasal organ: extended period of postnatal growth in size and evidence for rapid cell turnover in the adult.

    abstract::The total number of neurosensory cells in the mouse vomeronasal organ was estimated during postnatal development by counting the cell density and measuring the total volume of the neurosensory cell layer. There is a 43% increase in neurosensory cell number between 1 and 4 months of age, followed by a 21% fall in cell ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)90675-7

    authors: Wilson KC,Raisman G

    更新日期:1980-03-03 00:00:00

  • Mu opioid receptor-containing neurons mediate electroacupuncture-produced anti-hyperalgesia in rats with hind paw inflammation.

    abstract::Previous studies showed that electroacupuncture (EA) significantly attenuates inflammatory hyperalgesia in a complete Freund's adjuvant (CFA)-induced inflammatory pain rat model. The present study demonstrates that pretreatment with Derm-sap, a selective toxin for neurons that contain mu opioid receptor (MOR), specifi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2005.05.008

    authors: Zhang RX,Wang L,Liu B,Qiao JT,Ren K,Berman BM,Lao L

    更新日期:2005-06-28 00:00:00

  • mu-Opioid receptor activation decreases N-type Ca2+ current in magnocellular neurons of the rat basal forebrain.

    abstract::Opioid modulation of calcium currents was studied in acutely dissociated rat basal forebrain neurons using the whole cell patch-clamp recording technique. The mu-opioid receptor agonist DAGO reversibly suppressed high-voltage activated calcium currents and slowed their rate of activation, while neither delta- nor kapp...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00206-0

    authors: Soldo BL,Moises HC

    更新日期:1997-05-30 00:00:00

  • Spontaneous voltage and current fluctuations in tissue cultured mouse dorsal root ganglion cells.

    abstract::Fetal mouse dorsal root ganglion (DRG) neurons were maintained in primary dissociated cell culture for periods of 7 days to 3 months. Intracellular recordings from these cells revealed the presence of spontaneous subthreshold potentials in 101/177 neurons studied. When measured at the resting membrane potential, these...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)91450-1

    authors: Mathers DA,Barker JL

    更新日期:1984-02-13 00:00:00