Abstract：
:The effects of continuous clonidine infusion (10 micrograms/kg/h for 10 days) and the cessation of this infusion on the circadian body temperature rhythm of the spontaneously hypertensive (SH) rat were examined. This circadian rhythm was blunted significantly during the infusion of clonidine. The fall in body temperature which normally occurs at the onset of each light phase was attenuated during the clonidine infusion, and as such, these rats displayed a relative hyperthermia over the light but not the dark phases. On cessation of infusion (24:00 h), a distinct hyperthermia occurred within the immediate dark phase and the subsequent light phase. The results demonstrate that the circadian control of body temperature is disturbed both during and after continuous clonidine infusion.
journal_name
Brain Resjournal_title
Brain researchauthors
Lewis SJ,Maccarrone C,Jarrott Bdoi
10.1016/0006-8993(86)91088-7subject
Has Abstractpub_date
1986-10-22 00:00:00pages
383-8issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(86)91088-7journal_volume
385pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:In the present study we found that mesencephalic trigeminal (Mes-V) neurons of the rat are innervated by nitrergic fibers and that nitric oxide (NO) modifies the electrophysiological properties of these cells. Mes-V neurons were surrounded by a network of fibers that contained neuronal nitric oxide synthase (nNOS); th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03776-9
更新日期：2003-01-17 00:00:00
abstract：:Commissural and ipsilateral intrinsic connections of the vestibular nuclear complex of cats were investigated using retrograde transport of horseradish peroxidase (HRP). HRP was microiontophoretically injected into limited areas (0.2-0.5 mm in diameter) of the respective vestibular nuclei. In the commissural connectio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91474-x
更新日期：1985-08-19 00:00:00
abstract：:The chronic dietary intake of essential polyunsaturated fatty acids (PUFAs) can modulate learning and memory by being incorporated into neuronal plasma membranes. Representatives of two PUFA families, the n-3 and n-6 types become integrated into membrane phospholipids, where the actual (n-6)/(n-3) ratio can determine ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03300-0
更新日期：2002-11-01 00:00:00
abstract：:Transforming growth factor-beta 1 (TGF-beta 1) is highly expressed in neural tissues following brain injuries. To determine a role of TGF-beta 1 in neural pathologies, axons of cultured rat hippocampal neurons were cut by local irradiation of laser beam, and the effect of TGF-beta 1 on neurite regeneration following a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00253-3
更新日期：1996-06-03 00:00:00
abstract：:Recent studies, which have shown an increase of plasma vasopressin (VP) in experimental motion sickness and the efficacy of VP antagonists for motion sickness, suggest an important role of VP in the development of vestibulo-autonomic responses. We have recently found evidence of the co-existence of vasopressinergic ne...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02799-8
更新日期：2001-09-28 00:00:00
abstract：:Olfactory bulbectomy (OBX) in rodents induces neurochemical and behavioral changes similar to those observed in individuals with depressive disorders. Our previous study suggested that OBX alters dopaminergic function in the striatum of mice; however, the effects on dopaminergic function in the hypothalamus is unknown...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2020.147015
更新日期：2020-11-01 00:00:00
abstract：:In most cases obesity, a major risk factor for diabetes mellitus type 2 and other associated chronic diseases, is generated by excessive eating. For a better understanding of eating behavior, it is necessary to determine how it is modulated by factors such as the calorie content of food, satiety and gender. Twelve hea...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.04.030
更新日期：2010-09-02 00:00:00
abstract：:Existing data on the expression of H(4) histamine receptor in the CNS are conflicting and inconclusive. In this report, we present the results of experiments that were conducted in order to elucidate H(4) receptor expression and localization in the brain, spinal cord, and dorsal root ganglia (DRG). Here we show that t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.11.018
更新日期：2009-01-23 00:00:00
abstract：:The effects of neonatal dopamine depletion on activity levels and locomotor patterns were tested in rats at 4 months of age. Measurements were taken using an activity pattern monitor. The lesioned group was significantly hypoactive in comparison to the control animals during the initial exposures to the monitor. Exami...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)91637-3
更新日期：1994-05-09 00:00:00
abstract：:Recent studies have shown that moving in synchrony with auditory stimuli boosts attention allocation and verbal learning. Furthermore rhythmic tones are processed more efficiently than temporally random tones ('timing effect'), and this effect is increased when participants actively synchronize their motor performance...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2017.11.022
更新日期：2019-08-01 00:00:00
abstract：:Using a specific antibody against each of the 4 catecholamine-synthesizing enzymes, dopamine or serotonin, we compared the localization of these substances in rat and mouse spinal cord with two kinds of fixative, such as paraformaldehyde and glutaraldehyde, and two types of sectioning technique, i.e. cryostat and micr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90202-8
更新日期：1988-12-13 00:00:00
abstract：:Responses of pyramidal neurons to ionophoretic kainate, quisqualate and N-methyl aspartate were studied in a submerged rat piriform cortex slice as a function of Ca2+ and Mg2+ concentrations. The results suggest that the channel activated by kainate is unusually influenced by Ca2+, excitotoxicity is Ca2+-dependent and...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90989-8
更新日期：1985-12-09 00:00:00
abstract：:The medial septal area has been implicated in the control of the magnocellular neurosecretory cells of the hypothalamus, and in particular, in the regulation of neurons secreting oxytocin. The present study investigated the hypothesis that this medial septal pathway originates in the subfornical organ. Brief electrica...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)01278-p
更新日期：1995-02-20 00:00:00
abstract：:Little is known about the cells or mechanisms of O2 chemoreception in vertebrates other than mammals. The purpose of this study, therefore, was to identify O2-sensitive chemoreceptors in a fish. Putative O2-sensitive chemoreceptors were dissociated from the gills of channel catfish, Ictalurus punctatus, and cultured. ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.03.085
更新日期：2006-05-30 00:00:00
abstract：:The concentration of soluble glial fibrillary acidic (GFA) protein and the specific activity of glutamine synthetase (GS) were estimated in 11 central nervous system (CNS) regions of the 90-day-old rat. Marked differences were observed in the regional distribution of these astrocyte marker proteins. The striatum and s...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90708-5
更新日期：1985-04-01 00:00:00
abstract：:The focal ischemia obtained in an animal model of middle cerebral artery occlusion (MCAo) causes the "core" of damage in the striatum and the "penumbra" of damage in the fronto-parietal cortex. The latter is mainly functionally affected and shows changes in nNOS and iNOS expression during the acute phase of ischemia. ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.11.029
更新日期：2007-02-09 00:00:00
abstract：:Brains of reptiles, Caiman crocodilus, were processed by standard immunocytochemical methodology using a polyclonal antibody to gamma-aminobutyric acid (GABA) raised in rabbit and a polyclonal antibody to glutamic acid decarboxylase (GAD) raised in sheep. No GABA(+) or GAD(+) cells or puncta were observed over any tha...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90068-6
更新日期：1988-08-02 00:00:00
abstract：:In chloralose-urethane anaesthetized cats and in one unanesthetized decerebrate cat, the possibility of a baroreceptor pathway exerting an inhibitory effect directly on the sympathetic preganglionic neurone (SPN) was examined. Stimulation of excitatory points in the brain stem and spinal cord evoked responses in T3 wh...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90212-2
更新日期：1981-09-07 00:00:00
abstract：:Horseradish peroxidase (HRP, 30% solution, 0.1-0.3 mul, 72 h) was injected unilaterally into the basal striatum (STR) and the dorsal ventricular ridge (DVR) of adult turtles (Chrysemys picta) in order to demonstrate the cells of origin of some afferents to these telencephalic structures. After selective STR injection,...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90161-x
更新日期：1976-05-21 00:00:00
abstract：:The alpha7 nicotinic acetylcholine receptor (nAChR) plays an important role in cognitive processes and has generated recent interest as a potential drug target for treating neurodegenerative disorders such as Alzheimer's disease (AD). The property of Ca(2+) permeation associated with alpha7 nAChR agonism may lead to C...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.01.069
更新日期：2009-04-10 00:00:00
abstract：:Neurogenesis might influence oligodendrogenesis and selectively instruct myelination in the mammalian brain. Running exercise could induce neurogenesis and protect the myelin sheaths in the dentate gyrus of AD mice. It is unclear whether running exercise can protect myelin sheaths in the absence of neurogenesis in the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2018.01.007
更新日期：2018-04-01 00:00:00
abstract：:In this study, we measured regional brain blood flow (BF) in rats during hypoxic exposure. Our data show the hypoxia-induced brain blood flow increase returned to baseline within 1 week as blood hemoglobin increased. Because this return to baseline occurred before capillary angiogenesis, this result suggests that the ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.08.046
更新日期：2004-11-19 00:00:00
abstract：:The immunohistochemical distributions of tyrosine hydroxylase (TH), calmodulin (CaM) and calcium/CaM-dependent protein kinase II (CaMKII) in the rat forebrain were compared quantitatively to confirm our previous finding that TH activity and dopamine synthesis in the brain are regulated by a calcium/CaM-dependent syste...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02271-0
更新日期：2002-04-12 00:00:00
abstract：:Threatening stimuli are thought to bias spatial attention toward the location from which the threat is presented. Although this effect is well-established in the visual domain, little is known regarding whether tactile attention is similarly affected by threatening pictures. We hypothesised that tactile attention migh...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.11.072
更新日期：2009-02-09 00:00:00
abstract：:Numerous studies with PC12 cells have suggested that the mitogen-activated protein (MAP) kinase pathway might play a major role in the neuronal differentiation that is induced by nerve growth factor (NGF). Cells of the PC12D subline extend neurites within several hours in response to NGF in the presence of inhibitors ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)01403-0
更新日期：1998-03-02 00:00:00
abstract：:Fluoro-Gold has been used previously to identify those trigeminal ganglion cells that innervate the central cornea. To examine the effects of Fluoro-Gold treatment on infection and spread of HSV in vivo, we measured the number of plaque forming units recovered from trigeminal ganglia 3 or 5 days after corneal scratch ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90137-c
更新日期：1993-10-15 00:00:00
abstract：:Endogenous opioid systems (i.e. opioids and opioid receptors) play a role in regulating neural development. Using the cerebellar cortex of 6-day-old rats, the most potent opioid peptides involved with cell proliferation were assessed. In both the external germinal (granule) layer (EGL), a germinative matrix giving ris...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)91585-o
更新日期：1991-03-01 00:00:00
abstract：:The pattern of generation of neurons in the albino rat superior colliculus has been studied in adult and fetal material. Neurons are generated between embryonic days 12 to 17, with rostrolateral colliculus in advance of caudomedial parts. More of the cells contributing to the deeper layers are generated early, while m...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(79)90004-0
更新日期：1979-03-23 00:00:00
abstract：:The jimpy gene is a sex-linked recessive mutation which produces severe hypomyelination throughout the central nervous system (CNS) in affected male mice. The female carrier also expresses the mutation, but the degree of hypomyelination varies considerably among the tracts. In the optic nerve, patches of unmyelinated ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90958-1
更新日期：1982-10-28 00:00:00
abstract：:The efficacy of 5 alpha-androstane-3 alpha,17 beta-diol (3 alpha-Androstanediol; 3 alpha-Diol) and 4-pregnen-3,20-dione (progesterone; P) in promoting analgesia was investigated. Ovariectomized rats received daily injections of 3 alpha-Diol (0.6, 3.0, 6.0 and 7.5 mg/kg) or vehicle and twice daily injections of estradi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01118-8
更新日期：1996-02-12 00:00:00
