Abstract:
:Basic fibroblast growth factor (FGF-2) isoforms of the adrenal medulla are differentially expressed during rat postnatal development. While the 18 and 23 kDa isoforms continuously rise towards the adult expression level, the 21 kDa isoform displays a peak expression at postnatal day 28. The peak expression of the 21 kDa isoform correlates with the peak of the corticosterone concentration during postnatal development. Together with the previously demonstrated increase of the 21 kDa isoform in the adrenal medulla in vivo after glucocorticoid administration these results suggest that the differential regulation of the FGF-2 isoforms could be a physiologically occurring mechanism.
journal_name
Brain Resjournal_title
Brain researchauthors
Meisinger C,Grothe Cdoi
10.1016/s0006-8993(97)00341-7subject
Has Abstractpub_date
1997-05-23 00:00:00pages
291-4issue
2eissn
0006-8993issn
1872-6240pii
S0006-8993(97)00341-7journal_volume
757pub_type
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