Differential expression of FGF-2 isoforms in the rat adrenal medulla during postnatal development in vivo.

Abstract:

:Basic fibroblast growth factor (FGF-2) isoforms of the adrenal medulla are differentially expressed during rat postnatal development. While the 18 and 23 kDa isoforms continuously rise towards the adult expression level, the 21 kDa isoform displays a peak expression at postnatal day 28. The peak expression of the 21 kDa isoform correlates with the peak of the corticosterone concentration during postnatal development. Together with the previously demonstrated increase of the 21 kDa isoform in the adrenal medulla in vivo after glucocorticoid administration these results suggest that the differential regulation of the FGF-2 isoforms could be a physiologically occurring mechanism.

journal_name

Brain Res

journal_title

Brain research

authors

Meisinger C,Grothe C

doi

10.1016/s0006-8993(97)00341-7

subject

Has Abstract

pub_date

1997-05-23 00:00:00

pages

291-4

issue

2

eissn

0006-8993

issn

1872-6240

pii

S0006-8993(97)00341-7

journal_volume

757

pub_type

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