Abstract：
:Power spectral analysis of the electroencephalogram (EEG) is a non-invasive method to examine infant brain maturation. Preterm fetal growth restricted (p-FGR) neonates display an altered EEG power spectrum compared to appropriate-for-gestational-age (AGA) peers, suggesting delayed brain maturation. Longitudinal studies investigating EEG power spectrum maturation in p-FGR infants are lacking, however. We thus aimed to investigate brain maturation using sleep EEG power spectral analysis in p-FGR infants compared to preterm and term AGA controls (p-AGA and t-AGA, respectively). EEG was recorded during spontaneous sleep in 13 p-FGR, 17 p-AGA and 19 t-AGA infants at 1 and 6 months post-term age. Infant sleep states (active and quiet sleep) were scored using standard criteria. Power spectral analysis of a single-channel EEG (C3-M2/C4-M1) was performed using Fast Fourier Transform. The EEG power spectrum was divided into delta (0.5-4 Hz), theta (4-8 Hz), alpha (8-12 Hz), sigma (12-14 Hz) and beta (14-30 Hz) frequency bands. Relative (%) powers and the spectral edge frequency were calculated. The spectral edge frequency was significantly higher in p-FGR infants compared to p-AGA controls in quiet sleep at 1 month post-term age (p < .01). This was due to significantly reduced %-delta and significantly increased %-theta, %-alpha and %-beta power (p < .01 for all) compared to p-AGA infants. p-FGR infants also showed significantly increased %-beta power compared to t-AGA infants (p < .05). No group differences were observed in active sleep or at 6 months post-term age. In conclusion, p-FGR infants show altered sleep EEG power spectrum maturation compared to AGA peers. However, changes resolved by 6 months post-term age.
journal_name
Brain Resjournal_title
Brain researchauthors
Cohen E,Wong FY,Wallace EM,Mockler JC,Odoi A,Hollis S,Horne RSC,Yiallourou SRdoi
10.1016/j.brainres.2017.10.010subject
Has Abstractpub_date
2018-01-01 00:00:00pages
180-186eissn
0006-8993issn
1872-6240pii
S0006-8993(17)30450-Xjournal_volume
1678pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Voltage-gated potassium (Kv) channels are essential components of neuronal excitability. The Kv3.4 channel protein is widely distributed throughout the central nervous system (CNS), where it can form heteromeric or homomeric Kv3 channels. Electrophysiological studies reported here highlight a functional role for this ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.10.090
更新日期：2008-01-16 00:00:00
abstract：:Immunohistochemical studies in rats have demonstrated dopaminergic input onto medium spiny neurons of the striatum. Medium spiny neurons, however, are known to consist of two major neuropeptide-specific types, those containing substance P (SP) and those containing enkephalin. Although both of these types have been sho...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90490-z
更新日期：1992-02-14 00:00:00
abstract：:Functional magnetic resonance imaging studies on episodic memory (EM) retrieval have used a variety of paradigms/contrasts to yield many diverse findings, which raises the need for an integrative multifactorial view. To address this need, I begin by proposing a fourstage, quasi-sequential model of network activity dur...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2020.147049
更新日期：2020-11-15 00:00:00
abstract：:Drebrins are developmentally regulated proteins found in chicken brain and are classified into two forms of the embryonic type (E1 and E2) and one form of the adult type (A). Although the time courses of their appearance are different from each other, the structures of the 3 forms are closely related. Two kinds of dre...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0169-328x(88)90027-7
更新日期：1988-11-01 00:00:00
abstract：:Indirect immunofluorescence cytochemistry of ovine corticotropin releasing factor (oCRF) was performed by use of an antiserum raised against a conjugate of oCRF and bovine thyroglobulin. The staining intensity was quantitated by use of an automated microfluorimeter. In cryostat sections of formaldehyde fixed oCRF cont...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)91458-6
更新日期：1984-02-13 00:00:00
abstract：:Accumulating evidence suggests that the neuropeptide substance P (SP) and its principal receptor neurokinin 1 (NK1) play a specific role in the behavioral response to opioids and stress that may help to initiate and maintain addictive behavior. In animal models, the NK1 receptor is required for opioids to produce thei...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2009.11.014
更新日期：2010-02-16 00:00:00
abstract：:Alterations in the membraneous organelles were studied in two experimental neuropathies: 2,5-hexanedione (2,5-HD) and beta,beta'-iminodiproprionitrile (IDPN), both of which exhibit massive neurofilamentous accumulation. The membranous organelles were stained using the diaminobenzidine potassium ferrocyanide (DPF) meth...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90489-4
更新日期：1983-06-06 00:00:00
abstract：:The low, middle, and high molecular mass neurofilament subunit proteins (NF-L, NF-M, and NF-H) co-polymerize to form neurofilaments (NFs). During development, NF subunit expression is highly regulated, and in neurodegenerative disease, aberrant regulation of this expression can lead to the formation of harmful aggrega...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.11.012
更新日期：2008-01-16 00:00:00
abstract：:To date several circuities in supraspinal site of the central nervous system have been known to engage in pain modulation. Lateral hypothalamus (LH) is known as part of the circuit of pain modulation among supraspinal sites. Its role in several animal pain models has been well defined. In this study, we examined the r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2020.146674
更新日期：2020-04-01 00:00:00
abstract：:Electrical stimulation of the dorsal hippocampal formation of the rat was employed to determine the effect of 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3), the hormonal form of vitamin D, on induced seizure thresholds. Stereotaxic injection of 100 micrograms or 50 micrograms 1,25-dihydroxyvitamin D3 in 2 microliter propyle...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)91153-3
更新日期：1984-04-23 00:00:00
abstract：:The syndrome of vacuous chewing movements (VCMs) in rats is similar in many respects to tardive dyskinesia (TD) in humans. Both syndromes are characterized by delayed onset of persistent orofacial dyskinesias in a sub-group of subjects chronically treated with neuroleptics. Using the rat model, we examined the role of...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00196-6
更新日期：1998-06-15 00:00:00
abstract：:In the search for cortical mechanisms subserving psychological phenomena, a better understanding of human cortical circuitry is crucial. In this report we describe aspects of intrinsic connectivity of supragranular layers in human visual cortex, revealed by extracellular injections of the anterograde tracer biocytin i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91148-8
更新日期：1992-10-30 00:00:00
abstract：:Previous studies have shown that muscarinic cholinergic agonists bind to 3 distinct receptor sites in brain, each being distinguished by their affinity for the agonists. Antagonists, on the other hand, bind to these sites with the same high affinity. The relative concentrations of the two high and the low affinity ago...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)91089-6
更新日期：1980-10-27 00:00:00
abstract：:Previous studies have indicated that central sensitization is a state of increased excitability of nociceptive neurons in the spinal dorsal horn following peripheral tissue injury and/or inflammation and astrocytes play an important role in the central sensitization. The current study investigated the role of amino ac...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2012.02.018
更新日期：2012-04-17 00:00:00
abstract：:There is a sizeable literature concerning basal ganglia (BG) functioning that is based on data from experiments employing a method of analysis that is traditionally used with other motor areas. A brief review of this literature is presented and the following conclusion is reached: as compared to the success of traditi...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/0165-0173(85)90010-4
更新日期：1985-06-01 00:00:00
abstract：:In our previous study, we have found that leucine-rich repeats and immunoglobulin-like domains 1(LRIG1) can improve the chemosensitivity in U251 cells whereas the role of LRIG1 in multidrug resistance (MDR) remains unknown. Here, we reported that LRIG1 can reverse MDR by inhibiting epidermal growth factor (EGF) recept...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.03.023
更新日期：2015-06-22 00:00:00
abstract：:The interrelationships between axonal conduction velocity, tetanic tension, twitch contraction time and rate of force development during a tetanus have been studied in 126 motor units from 12 cat medial gastrocnemius muscles. While the range of axonal conduction velocities for slow- (contraction time greater than 45 m...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(75)90542-9
更新日期：1975-06-27 00:00:00
abstract：:Intracellular recordings were made from rabbit nodose ganglion cells in vitro. Morphine (up to 100 micro M), normorphine (up to 10 micro M) and D-Ala2, Leu5-enkephalin (DADLE) (up to 5 micro M) each had no detectable effect on the electrical properties of the cell membrane, except for local anesthetic-like actions at ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)91066-0
更新日期：1981-09-21 00:00:00
abstract：PURPOSE:Diffusion kurtosis imaging (DKI) is a MRI technique which can measure alterations in the diffusion of water molecules to reflect tissue changes in both white and grey matter. This study evaluated the potential of DKI for the early diagnosis of radiation-induced temporal lobe changes in the grey and white matter...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2016.07.041
更新日期：2016-10-01 00:00:00
abstract：:Many AIDS patients suffer from cognitive impairments including deficits in learning and memory. The Human Immunodeficiency Virus-1 (HIV-1) envelope glycoprotein gp120 is one possible mediator of these impairments. This is because gp120 activates brain microglial cells and astrocytes, and in vivo activation of glia lea...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)02445-2
更新日期：2000-04-07 00:00:00
abstract：:5-Hydroxytryptamine (5-HT, serotonin), synthesized in midbrain raphe nuclei and released in various hypothalamic sites, decreases food intake but the specific 5-HT receptor subtypes involved are controversial. Here, we have studied changes in the regional density of binding to 5-HT receptors and transporters and the l...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)02055-7
更新日期：1999-11-13 00:00:00
abstract：:Adrenergic innervation of tibial and vagus nerves was studied after 1-16 weeks duration of streptozotocin (STZ)-induced diabetes in rats. Sucrose-phosphate glyoxylic acid (SPG) histochemistry and the formaldehyde-induced fluorescence (FIF) method were used to demonstrate adrenergic nerve fibers in the epi-perineurial ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91095-x
更新日期：1990-04-09 00:00:00
abstract：:In order to improve clinical trial design and translation of normobaric oxygen (NBO) treatment of ischemic stroke, NBO treatment parameters need to be better understood. This study investigated NBO treatment efficacy at two different stroke severities and two NBO treatment durations in rats. For the 60-min middle cere...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2016.01.030
更新日期：2016-03-15 00:00:00
abstract：:We have examined the effects of isotonic hypovolemia on the expression of the neuronal nitric oxide synthase (nNOS) gene in the paraventricular (PVN) and supraoptic nuclei (SON) of the rat, using in situ hybridization histochemistry with a 35S-labelled oligodeoxynucleotide probe complementary to nNOS mRNA. Intraperito...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)01531-x
更新日期：1998-04-20 00:00:00
abstract：:Modulation of gamma-aminobutyric acid (GABA)-mediated inhibition, and glutamate-mediated excitation by highly selective mu and delta opioid agonists was studied using intracellular recordings of CA1 pyramidal neuron synaptic responses in superfused hippocampal slices. Equimolar concentrations of the selective mu agoni...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91312-3
更新日期：1992-10-16 00:00:00
abstract：:Anisomycin is both a well-established protein synthesis inhibitor and a potent activator of the p38/JNK MAPK pathway. It has been used to block the late phase of long-term potentiation (LTP) and long-term depression (LTD) in hippocampus. In this study, we have found that anisomycin produces a time-dependent decline in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.02.015
更新日期：2006-04-26 00:00:00
abstract：:Mutant Cu/Zn superoxide dismutase (SOD1) associated with familial amyotrophic lateral sclerosis (FALS) causes selective motor neuron loss through unknown mechanisms of cell damage. Damaged neurons frequently undergo apoptosis mediated by the p53 cell survival regulator. We therefore studied whether motor neuron diseas...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02745-1
更新日期：2000-10-06 00:00:00
abstract：:In a previous study we reported significant elevations of TRH in neocortex, hippocampus and combined amygdala/pyriform cortex in rats 48 h after the last of a series of stage 5 kindled seizures. In the present study, to determine whether the increases in TRH were proportional to the intensity of the convulsions, and t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91330-j
更新日期：1990-08-13 00:00:00
abstract：:In synaptosomal preparations from rat cerebral cortex, ouabain-sensitive Rb+ uptake was stimulated by ethanol (20-80 mM). Based on differential sensitivity to ouabain, 80% of this Na+,K(+)-ATPase activity represented activity of the alpha 1 isozyme while 20% was due to the alpha 2 and/or alpha 3 isozymes (alpha 2/ alp...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90386-7
更新日期：1994-08-08 00:00:00
abstract：:Administration of either Tyr-D-Ala-Gly-MePhe-Gly(ol) (DAGO), a mu-opioid agonist, or nicotine into the VTA (A10) caused an increase in both dopamine (DA) and its metabolite levels in both the A10 region and DA nerve terminals in the nucleus accumbens of rats when assessed with dual probe brain dialysis. These findings...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90087-4
更新日期：1993-10-08 00:00:00
