Increased binding at 5-HT(1A), 5-HT(1B), and 5-HT(2A) receptors and 5-HT transporters in diet-induced obese rats.

abstract：:In this study, we observed the chronological alterations of neurofilament 150 (NF-150) immunoreactivity in the gerbil hippocampus and dentate gyrus after 5 min transient forebrain ischemia. NF-150 immunoreactivity in the sham-operated group was mainly detected in mossy fibers and in the hilar region of the dentate gyr...

journal_title：Brain research

authors： Hwang IK,Do SG,Yoo KY,Kim DS,Cho JH,Kwon YG,Lee JY,Oh YS,Kang TC,Won MH

更新日期：2004-07-30 00:00:00

abstract：:This study examined the involvement of N-methyl-D-aspartate receptors (NMDARs) in experience-dependent synaptic plasticity. Rats chronically received an NMDA receptor antagonist (AP5) or saline (SAL) and were exposed to individual cages (IC) or environmental enrichment (EC). AP5 impaired measures of hippocampal-depend...

journal_title：Brain research

authors： Foster TC,Fugger HN,Cunningham SG

更新日期：2000-07-14 00:00:00

abstract：:We studied the effects of transcranial magnetic stimulation (TMS) on muscle activation patterns and joint kinematics during oscillatory movements of a joint within a two-joint (elbow-wrist) synergy. Healthy young adults (N=8) performed cyclic movements in one of the joints while the other joint was or was not involved...

journal_title：Brain research

authors： Latash ML,Danion F,Bonnard M

更新日期：2003-01-31 00:00:00

abstract：:Nocistatin, a product of the same precursor as nociceptin/orphanin FQ (N/OFQ), has been shown to antagonize effects of N/OFQ. N/OFQ stimulates feeding, most probably by inhibiting activation of neurons containing oxytocin (OT) and vasopressin (VP), peptides considered as satiety factors, and implicated in the developm...

journal_title：Brain research

authors： Olszewski PK,Shaw TJ,Grace MK,Billington CJ,Levine AS

更新日期：2000-07-28 00:00:00

abstract：:We have previously identified a cell senescence-related, detergent-insoluble cytoplasmic protein referred to as terminin, and have presented the development-dependent modification of terminin polypeptides in rat brain. In the present study, we characterize biochemically and immunocytochemically terminin expression in ...

journal_title：Brain research

authors： Yang G,Wang E

更新日期：1994-05-02 00:00:00

abstract：:Chemotherapy-induced pain is the most common treatment-limiting complication encountered by cancer patients receiving taxane-, vinca alkaloid- or platin-based chemotherapy. Several lines of evidence indicate that activation of pro-inflammatory cascades involving the release of cytokines including tumor necrosis factor...

journal_title：Brain research

authors： Cata JP,Weng HR,Dougherty PM

更新日期：2008-09-10 00:00:00

abstract：:In order to establish the basic connectivity of physiologically identified somatosensory regions of the thalamus and telencephalon in the pigeon, injections of wheatgerm agglutinin-horseradish peroxidase were made under electrophysiological control and the projections were charted following conventional neurohistochem...

journal_title：Brain research

authors： Wild JM

更新日期：1987-06-02 00:00:00

abstract：:The morphological and physiological identification of the cells in the inner retina of Japanese dace was made by means of intracellular single cell recording and dye injection techniques. Our flat mounts and physiological classification revealed that 97 out of 102 sample cells were amacrine cells except for 3 transien...

journal_title：Brain research

authors： Chino YM,Hashimoto Y

更新日期：1986-05-07 00:00:00

abstract：:Previous immunocytochemical, physiological, and molecular studies have reported that the Syrian hamster lacks a shortwave-sensitive (S) cone photopigment but retains circadian responses to ultraviolet (UV) light. Using opsin antibodies and a sensitive detection protocol, we here show that S opsin immunoreactivity colo...

journal_title：Brain research

authors： Glösmann M,Ahnelt PK

更新日期：2002-03-01 00:00:00

abstract：:Using a double-label immunofluorescence method, we analyzed the time course of the appearance of Fos and Jun in the nuclei of supraoptic nucleus (SON) neurons following intraperitoneal injection of hypertonic saline. Fos and Jun immunostaining appeared within 30 min, peaked at 90-120 min, and disappeared 4-5 h later. ...

journal_title：Brain research

authors： Wang K,Guldenaar SE,McCabe JT

更新日期：1997-01-23 00:00:00

abstract：:The role of calcium and protein kinases in rhythmic activity induced by muscarinic receptor activation in the CA1 area in rat hippocampal slices was investigated. Extracellular recording showed that carbachol (20 microM) induced synchronized field potential activity with a dominant frequency of 7.39+/-0.68 Hz. Pretrea...

journal_title：Brain research

authors： Alberi S,Boeijinga PH,Raggenbass M,Boddeke HW

更新日期：2000-07-28 00:00:00

abstract：:We sought to characterize regional heterogeneity of astrocytes using adrenergic receptor sites as cellular markers. Primary cultures made from 6 regions of neonatal rat brain consisted almost exclusively of astrocytes. Membranes from astrocytes cultured 1-3 weeks were prepared for radioligand binding assays of beta- a...

journal_title：Brain research

authors： Ernsberger P,Iacovitti L,Reis DJ

更新日期：1990-05-28 00:00:00

abstract：:In order to elucidate the roles of hippocampal nitric oxide (NO) synthesis in working and reference memory performance of rats, the effects of intrahippocampal injections of the NO synthase inhibitor, NG-nitro-L-arginine methyl ester (L-NAME), on this behavior were examined with a three-panel runway task. In the worki...

journal_title：Brain research

authors： Ohno M,Yamamoto T,Watanabe S

更新日期：1993-12-31 00:00:00

abstract：:As measured by extracellular single-cell recording, the responses to adenosine triphosphate (ATP) by ATP-sensitive chemoreceptors (ATP cells) on the olfactory organ of the spiny lobster are markedly suppressed by adenosine diphosphate (ADP), adenosine monophosphate (AMP) and to a lesser extent, adenosine, when each is...

journal_title：Brain research

authors： Gleeson RA,Carr WE,Trapido-Rosenthal HG

更新日期：1989-09-11 00:00:00

abstract：:1-Methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) was used to lesion the substantia nigra of rodents to look for changes in various animal models of epilepsy and seizures. MPTP, acutely administered to C57BL/6J mice, could cause seizures at high doses and enhanced maximal electroshock seizures at lower doses. Older ...

journal_title：Brain research

authors： Van Ness PC,Olsen RW,Verity MA

更新日期：1989-12-18 00:00:00

abstract：:The effects of oligemia (moderate ischemia) on the brain need to be explored because of the potential role of subtle microvascular changes in vascular cognitive impairment and dementia. Chronic bilateral common carotid artery occlusion (BCCAO) in adult rats has been used to study effects of oligemia (hypoperfusion) us...

journal_title：Brain research

authors： Schmidt-Kastner R,Aguirre-Chen C,Saul I,Yick L,Hamasaki D,Busto R,Ginsberg MD

更新日期：2005-08-02 00:00:00

abstract：:Rats with unilateral 6-hydroxydopamine lesions of the substantia nigra became briefly sedated and hypothermic after the acute injection of nicotine s.c. (0.4 or 0.8 mg/kg free base). When nicotine was repeated 5 days per week there was rapid tolerance for the sedation and slower tolerance for the hypothermia and the l...

journal_title：Brain research

authors： Lapin EP,Maker HS,Sershen H,Hurd Y,Lajtha A

更新日期：1987-03-31 00:00:00

abstract：:Administration of benzodiazepines at appropriate times in the circadian cycle induce phase-shifts in circadian locomotor activity. The possibility that benzodiazepine-induced shifts are mediated at the level of the suprachiasmatic nuclei (SCN), identified as the circadian pacemaker in mammals, was examined electrophys...

journal_title：Brain research

authors： Mason R,Biello SM,Harrington ME

更新日期：1991-06-21 00:00:00

abstract：:Intracerebral hemorrhage (ICH) is a devastating stroke with no clinically proven treatment. Deferoxamine (DFX), an iron chelator, is a promising therapy that lessens edema, mitigates peri-hematoma cell death, and improves behavioral recovery after whole-blood-induced ICH in rodents. In this model, blood is directly in...

journal_title：Brain research

authors： Warkentin LM,Auriat AM,Wowk S,Colbourne F

更新日期：2010-01-14 00:00:00

abstract：:The characterization of motor and cognitive dysfunctions following a neonatal ischemic injury is a prerequisite to investigate putative pharmacological interventions. To this end, in the present study, we evaluated the long-lasting behavioral alterations occurring after a hypoxic/ischemic injury obtained by the combin...

journal_title：Brain research

authors： Balduini W,De Angelis V,Mazzoni E,Cimino M

更新日期：2000-03-24 00:00:00

abstract：:Our previous studies have shown that tumor necrosis factor-alpha (TNF-alpha) activates solitary nucleus neurons involved in vago-vagal reflex control of gastric motility. Here, we describe the dual role of TNF-alpha as also modulating neurons in the dorsal motor nucleus of the vagus (DMN) that respond to gastric diste...

journal_title：Brain research

authors： Emch GS,Hermann GE,Rogers RC

更新日期：2002-10-04 00:00:00

abstract：:Spatial learning and memory in rodents represent close equivalents of human episodic declarative memory, which is especially sensitive to cerebral aging, neurodegeneration, and various neuropsychiatric disorders. Many tests and protocols are available for use in laboratory rodents, but Morris water maze and radial-arm...

journal_title：Brain research

authors： Pooters T,Van der Jeugd A,Callaerts-Vegh Z,D'Hooge R

更新日期：2015-09-24 00:00:00

abstract：:A recent physiological report suggested that neurotensin could inhibit the vasopressin releasing from vasopressin-producing neurons in the hypothalamic paraventricular nucleus but not in the supraoptic nucleus. In the present study, the synaptic relationship between the neurotensin-like immunoreactive and vasopressin-...

journal_title：Brain research

authors： Wang QP,Guan JL,Ochiai H,Nakai Y

更新日期：1999-07-10 00:00:00

abstract：:Corticosterone influences emotion and cognition via actions in a diversity of corticolimbic structures, including the amygdala. Since extracellular levels of corticosterone in brain have rarely been studied, we characterized a specific and sensitive enzymatic immunoassay for microdialysis quantification of corticoster...

journal_title：Brain research

authors： Bouchez G,Millan MJ,Rivet JM,Billiras R,Boulanger R,Gobert A

更新日期：2012-05-03 00:00:00

abstract：:Using the teased fiber recording method, we have compared pathophysiological properties of afferent axons injured in the infraorbital nerve (ION) vs the sciatic nerve in rats. Both myelinated and unmyelinated axons ending in ION neuromas produced much less ongoing discharge than those ending in sciatic nerve neuromas....

journal_title：Brain research

authors： Tal M,Devor M

更新日期：1992-05-01 00:00:00

abstract：:The hypothalamic angiotensin II (Ang II) system plays an important role in pituitary hormone release. Little is known about this system in the mouse brain. We studied the distribution of angiotensin-converting-enzyme (ACE), Ang II, Ang II receptor subtypes, and vasopressin in the hypothalamus of adult male mice. Autor...

journal_title：Brain research

authors： Jöhren O,Imboden H,Häuser W,Maye I,Sanvitto GL,Saavedra JM

更新日期：1997-05-23 00:00:00

abstract：:In the present studies we have examined the effects of a new calcium channel blocker, LY393615 ((N-Butyl-[5,5-bis-(4-fluorophenyl)tetrahydrofuran-2-yl]methylamine hydrochloride, NCC1048) in a model of hypoxia-hypoglycaemia in vitro and in a gerbil model of global and in two rat models of focal cerebral ischaemia in vi...

journal_title：Brain research

authors： O'Neill MJ,Hicks CA,Ward MA,Osborne DJ,Wishart G,Mathews KS,McLaughlin DP,Stamford JA,McCarty DR,Patrick KE,Roman C,Fleisch JH,Gilmore J,Boot JR

更新日期：2001-01-05 00:00:00

abstract：:Estrogen has previously been shown to significantly change sympathetic and parasympathetic system output via an action within the central nuclei responsible for regulating autonomic tone. These estrogen-induced changes were observed within 30 min of systemic administration and could be blocked by the direct microinjec...

journal_title：Brain research

authors： Saleh TM,Connell BJ,McQuaid T,Cribb AE

更新日期：2003-11-14 00:00:00

abstract：:Homer1a is implicated in depression in humans and depression-like behavior in mice. To further understand the role of Homer1a in stress-induced emotional changes, we applied very mild stress to Homer1a knockout (H1a KO) mice. The wild-type (WT) and H1a KO mice were restrained for 2h daily for 7 consecutive days at the...

journal_title：Brain research

authors： Shui Y,Wang L,Luo X,Uchiumi O,Yamamoto R,Sugai T,Kato N

更新日期：2015-04-24 00:00:00

abstract：:The behavioural response following infusion of a novel, stable substance P (SP) analogue, DiMe-C7, into the ventral tegmental area (VTA) of rats was characterized and contrasted with the response to an equal dose of the parent compound SP. DiMe-C7 produced a longer-lasting behavioural stimulation than SP as evidenced ...

journal_title：Brain research

authors： Eison AS,Eison MS,Iversen SD

更新日期：1982-04-22 00:00:00