Ectopic discharge in injured nerves: comparison of trigeminal and somatic afferents.

abstract：:This study determined baroreceptor reflex (BR) function in conscious rats which had received sham or electrolytic lesions of the anteroventral third ventricle (AV3V) 54-56 days previously. Resting mean arterial pressure (MAP) and heart rate (HR) values of the AV3V-lesion rats were similar to those of sham-lesion rats ...

journal_title：Brain research

authors： Lewis SJ,Whalen EJ,Beltz TG,Johnson AK

更新日期：1999-07-24 00:00:00

abstract：:In the present study, we characterized the evoked electrical activity from T(13) to S(2) dorsal roots (DRs) during glass probe-stimulation of the vagina-cervix-uterus junction (VCUJ) of female Wistar rats. The results showed that gentle stimulation of VCUJ evoked high-amplitude electrical activity in L(3) and L(6) DRs...

journal_title：Brain research

authors： Tovar A,Lara-Garcia M,Cruz Y,Pacheco P

更新日期：2013-02-16 00:00:00

abstract：:Interhemispheric connections were studied by injecting a mixture of horseradish peroxidase (HRP) and wheatgerm agglutinin conjugated with horseradish peroxidase (WGA-HRP) into multiple sites in dorsolateral occipital and parietal cortex of one cerebral hemisphere of three galagos (Galago crassicaudatus) and two owl mo...

journal_title：Brain research

authors： Beck PD,Kaas JH

更新日期：1994-07-18 00:00:00

abstract：:The effect of chronic ethanol administration on the density of basket cells in the dentate gyrus of mice selectively bred for their sensitivity to acute ethanol exposure (long-sleep, LS and short-sleep, SS) was assessed in two experiments. In addition, the effect of chronic ethanol on the density of dentate granule ce...

journal_title：Brain research

authors： Scheetz AJ,Markham JA,Fifková E

更新日期：1988-09-20 00:00:00

abstract：:Cytotoxic effects of L-glutamate and related compounds were investigated on rat glioma C6 cells in vitro. Within 12-24 h, addition of glutamate to the culture medium, resulted in degeneration of the C6 cells. The ED50 for glutamate-induced damage was about 4 mM. Seventeen structural analogues of glutamate, including a...

journal_title：Brain research

authors： Kato S,Higashida H,Higuchi Y,Hatakenaka S,Negishi K

更新日期：1984-06-15 00:00:00

abstract：:The spinal cord projections of the 3 main forelimb nerves-median, radial and ulnar, were studied in the rat dorsal horn with transganglionic transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP), or using the disappearance of fluoride resistant acid phosphatase (FRAP) after nerve section. The projection ...

journal_title：Brain research

authors： Castro-Lopes JM,Coimbra A

更新日期：1991-03-01 00:00:00

abstract：:We have applied a technique involving multi-channel linear filtering to the problem of sorting and identifying singly unit neuronal activity in records containing several simultaneously active units. The technique is effective even when the waveforms of two or more nerve impulses are superimposed. We have applied it s...

journal_title：Brain research

authors： Roberts WM,Hartline DK

更新日期：1975-08-22 00:00:00

abstract：:Adenine and guanine nucleotides have been shown to exert multiple roles in central and peripheral nervous systems, and the sequential breakdown of these nucleotides by enzymatic systems is an important step in the modulation of their extracellular effects. The aim of this study was to investigate whether nucleotide hy...

journal_title：Brain research

authors： Cruz Portela LV,Oses JP,Silveira AL,Schmidt AP,Lara DR,Oliveira Battastini AM,Ramirez G,Vinadé L,Freitas Sarkis JJ,Souza DO

更新日期：2002-09-20 00:00:00

abstract：:Work with ion-selective microelectrodes on the retina of the honeybee drone has shown that potassium is released from photoreceptors during activity and enters glial cells. Measurements of the extracellular voltage gradients indicate that, in this preparation, currents flowing through the glial cells in the 'spatial b...

journal_title：Brain research

authors： Gardner-Medwin AR,Coles JA,Tsacopoulos M

更新日期：1981-03-30 00:00:00

abstract：:Neurodegenerative disorders have attracted attention in last decades due to their high incidence in the world. The p53/miR-34a axis triggers apoptosis and suppresses viability in multiple types of cells, but little is known about its role in neurodegenerative diseases. In this study, we showed that presenilin (PS)-2, ...

journal_title：Brain research

authors： Li LH,Tu QY,Deng XH,Xia J,Hou DR,Guo K,Zi XH

更新日期：2017-05-01 00:00:00

abstract：:Genetic abnormalities in amyloid precursor protein (APP) are associated with Down's syndrome and familial Alzheimer's disease where hallmark plaques contain A beta peptides derived from APP. Both APP and its derivatives are implicated in neurodegenerative processes and may play important physiological and pathophysiol...

journal_title：Brain research

authors： Senechal Y,Prut L,Kelly PH,Staufenbiel M,Natt F,Hoyer D,Wiessner C,Dev KK

更新日期：2008-12-03 00:00:00

abstract：:Defeat stress in mice, a model of social stress, increases benzodiazepine receptor binding as measured by specific [3H]Ro15-1788 binding in vivo, but not by [3H]flunitrazepam binding in vitro. This increase occurs rapidly, by 20 min following exposure to stress, and resolves by 60 min. Increased benzodiazepine recepto...

journal_title：Brain research

authors： Miller LG,Thompson ML,Greenblatt DJ,Deutsch SI,Shader RI,Paul SM

更新日期：1987-06-30 00:00:00

abstract：:Extracellular signal-regulated kinase 1/2 (ERK1/2) plays diverse roles in the central nervous system. Activation of ERK1/2 has been observed in various types of neuronal excitation, including seizure activity in vivo and in vitro. However, studies examining ERK1/2 activity and its substrate phosphorylation in parallel...

journal_title：Brain research

authors： Yamagata Y,Nairn AC

更新日期：2015-11-02 00:00:00

abstract：:A comparison was made of the effects of left and right cerebral decortication on cytotoxic activity of natural killer and natural cytotoxic lymphocytes in the mouse. Natural killer cytotoxic activity was significantly reduced after right decortication, whereas left decortication led to a less pronounced, though still ...

journal_title：Brain research

authors： Belluardo N,Mudò G,Cella S,Bindoni M

更新日期：1990-08-06 00:00:00

abstract：:In degenerating frog sciatic nerves an in situ perfusion technique was used to measure the permeability coefficient-surface area product (PA) of endoneurial capillaries to [14C]sucrose, and the endoneurial vascular space (V). Both PA and V started to increase after the 3rd day of degeneration. The increase in PA peake...

journal_title：Brain research

authors： Weerasuriya A

更新日期：1988-03-29 00:00:00

abstract：:The role of GABA in NMDA-dependent long term depression (LTD) in the medial vestibular nuclei (MVN) was studied on rat brainstem slices. High frequency stimulation (HFS) of the primary vestibular afferents induces a long lasting reduction of the polysynaptic (N2) component of the field potentials recorded in the dorsa...

journal_title：Brain research

authors： Grassi S,Della Torre G,Capocchi G,Zampolini M,Pettorossi VE

更新日期：1995-11-20 00:00:00

abstract：:Erythropoietin (EPO) provides neuroprotection and neurorestoration after traumatic brain injury (TBI). The EPO doses used for treatment of TBI significantly increase hematocrit, which may affect the efficacy of EPO therapy for TBI. The aim of this study was to investigate whether normalization of hematocrit would affe...

journal_title：Brain research

authors： Zhang Y,Xiong Y,Mahmood A,Meng Y,Qu C,Schallert T,Chopp M

更新日期：2009-10-19 00:00:00

abstract：:Traumatic brain injury (TBI) in humans typically produces neurological suppression and a longer lasting impairment of memory clinically defined as post-traumatic amnesia. An animal model that reliably reproduces the physiological changes associated with TBI was used to assess the memory deficits following brain injury...

journal_title：Brain research

authors： Gorman LK,Shook BL,Becker DP

更新日期：1993-06-18 00:00:00

abstract：:The distinction between neural mechanisms of explicit and implicit expressions of memory has been well studied at the retrieval stage, but less at encoding. In addition, dissociations obtained in many studies are complicated by methodological difficulties in obtaining process-pure measures of different types of memory...

journal_title：Brain research

authors： Meng Y,Ye X,Gonsalves BD

更新日期：2014-10-17 00:00:00

abstract：:The present study investigated the effect of dextromethorphan and 6,7-dinitroquinoxaline-2,3-dione (DNQX) pre-treatment on the development of cocaine- and lidocaine-induced seizures. The dopaminergic action of cocaine was also studied. The NMDA antagonist dextromethorphan and the non-NMDA (AMPA/kainate) antagonist DNQ...

journal_title：Brain research

authors： Barat SA,Abdel-Rahman MS

更新日期：1997-05-09 00:00:00

abstract：:Recent anatomical evidence suggests that the shell of the nucleus accumbens, the bed nucleus of the stria terminalis, and the central nucleus of the amygdala, together referred to as the extended amygdala, may play a role in opiate dependence. The bed nucleus of the stria terminalis and the shell of the nucleus accumb...

journal_title：Brain research

authors： Walker JR,Ahmed SH,Gracy KN,Koob GF

更新日期：2000-01-31 00:00:00

abstract：:The trisomy-16 mouse is considered to be a model of human trisomy-21 (Down syndrome). We have examined the electrical membrane properties of cultured dorsal root ganglion (DRG) neurons from normal and trisomy-16 fetuses. Trisomy-16 neurons had significantly accelerated rates of action potential depolarization and repo...

journal_title：Brain research

authors： Ault B,Caviedes P,Rapoport SI

更新日期：1989-04-17 00:00:00

abstract：:Effects of alpha-adrenoceptor agents on electrophysiologically and immunohistochemically identified supraoptic nucleus (SON) vasopressin (VP) units were investigated by intracarotid infusion. Clonidine, an alpha 2-adrenoceptor agonist always excited SON units and alpha 2-adrenoceptor antagonists consistently inhibited...

journal_title：Brain research

authors： Mitchell LD,Callahan MF,Wilkin LD,Johnson AK

更新日期：1986-12-10 00:00:00

abstract：:Previous studies have indicated that amyloid precursor protein (APP) might be a trophic agent in the nervous system, possibly through the regulation of cell adhesion and the protease/protease inhibitor activity. Additionally, APP is upregulated during the development of the nervous system. In order to further study th...

journal_title：Brain research

authors： Masliah E,Mallory M,Ge N,Saitoh T

更新日期：1992-10-16 00:00:00

abstract：:The role of cat's primary auditory cortex (AI) in both pattern discrimination and sound localization has been demonstrated by observing that ablations of it disrupt these functions. This research studied effective connectivity variations as a function of modifications in the temporal pattern of acoustic stimulation. R...

journal_title：Brain research

authors： Espinosa IE,Gerstein GL

更新日期：1988-05-31 00:00:00

abstract：:Mesenchymal stem cell (MSC) transplantation has been reported to improve neurologic function after ischemic injury. However, the detailed mechanisms by which MSCs promote functional recovery are not fully understood. Interleukin-10 (IL-10) is a well-known anti-inflammatory cytokine with neuroprotective effects with re...

journal_title：Brain research

authors： Li J,Zhu H,Liu Y,Li Q,Lu S,Feng M,Xu Y,Huang L,Ma C,An Y,Zhao RC,Wang R,Qin C

更新日期：2010-06-02 00:00:00

abstract：:In the present study, we used an immunocytochemical technique at the electron microscopic level to determine if there are changes in the glutamate and GABA neurotransmitter content of the hippocampus of genetic absence epilepsy rats from Strasbourg (GAERS). We also investigated if there was mossy fiber reorganization....

journal_title：Brain research

authors： Sirvanci S,Meshul CK,Onat F,San T

更新日期：2003-10-24 00:00:00

abstract：:Previous studies have reported that schizophrenia (SZ) patients showed selective reinforcement learning deficits and abnormal feedback-related event-related potential (ERP) components. However, how the brain networks and their topological properties evolve over time during transient feedback-related cognition processi...

journal_title：Brain research

authors： Zhao Z,Wang C,Yuan Q,Zhao J,Ren Q,Xu Y,Li J,Yu Y

更新日期：2020-11-01 00:00:00

abstract：:The expression of two embryonic intermediate filaments, nestin and vimentin, in the rat brain at days 0 (control), 1, 4, 7 and 14 post-cryoinjury was studied to elucidate their roles in brain injury. Western blot analysis showed that both nestin and vimentin expressions in the ipsilateral cerebral cortex were signific...

journal_title：Brain research

authors： Moon C,Ahn M,Kim S,Jin JK,Sim KB,Kim HM,Lee MY,Shin T

更新日期：2004-12-03 00:00:00

abstract：:Structures of the medial temporal lobes are recognized to play a central role in memory processing and to be the primary sites of deterioration in Alzheimer disease (AD). Mild cognitive impairment (MCI) represents potentially an intermediate state between normal aging and AD. Proton magnetic resonance spectroscopy (MR...

journal_title：Brain research

authors： Chantal S,Braun CM,Bouchard RW,Labelle M,Boulanger Y

更新日期：2004-04-02 00:00:00